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Search results 301 to 377 out of 377 for Dsc2

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:1794820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824396
Age: embryonic day 14.5
Image: euxassay_004326_16
Specimen Label: euxassay_004326_16
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:1794820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824396
Age: embryonic day 14.5
Image: euxassay_004326_17
Specimen Label: euxassay_004326_17
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:20182
Assay Type: RNA in situ
Annotation Date: 2015-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5636047
Age: embryonic day 13.5
Note: Expression was more prominent over the inner cell layers of the downgrowth.
Specimen Label: 6d
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:20182
Assay Type: RNA in situ
Annotation Date: 2015-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5636047
Age: embryonic day 14.5
Note: Expression was more strongly over the inner cell layers of the downgrowth. Lower level expression in the presumptive matrix region.
Specimen Label: 6e
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:20182
Assay Type: RNA in situ
Annotation Date: 2015-05-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672024
Stage: TS24
Assay Id: MGI:5636047
Age: embryonic day 16.5
Note: Barely detectable.
Specimen Label: 6f
Detected: false
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:1794820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824396
Age: embryonic day 14.5
Image: euxassay_004326_12
Specimen Label: euxassay_004326_12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:1794820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824396
Age: embryonic day 14.5
Image: euxassay_004326_13
Specimen Label: euxassay_004326_13
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:1794820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824396
Age: embryonic day 14.5
Image: euxassay_004326_14
Specimen Label: euxassay_004326_14
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:1794820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824396
Age: embryonic day 14.5
Image: euxassay_004326_15
Specimen Label: euxassay_004326_15
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:1794820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824396
Age: embryonic day 14.5
Image: euxassay_004326_16
Specimen Label: euxassay_004326_16
Detected: true
Specimen Num: 16
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•
GXD Expression
GXD Expression
 
Probe: MGI:1794820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824396
Age: embryonic day 14.5
Image: euxassay_004326_17
Specimen Label: euxassay_004326_17
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:1794820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824396
Age: embryonic day 14.5
Image: euxassay_004326_18
Specimen Label: euxassay_004326_18
Detected: true
Specimen Num: 18
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Publication
- | J:71017
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, clone IMAGE: 3498302, mRNA, partial cds
Pages: BC004663
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Publication
9389456 | J:44061
First Author: Chidgey MA
Year: 1997
Journal: Dev Dyn
Title: Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development.
Volume: 210
Issue: 3
Pages: 315-27
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Publication
8486729 | J:4712
First Author: Buxton RS
Year: 1993
Journal: J Cell Biol
Title: Nomenclature of the desmosomal cadherins.
Volume: 121
Issue: 3
Pages: 481-3
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Publication
14523549 | J:86273
First Author: Huber O
Year: 2003
Journal: Cell Mol Life Sci
Title: Structure and function of desmosomal proteins and their role in development and disease.
Volume: 60
Issue: 9
Pages: 1872-90
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Publication
7894164 | J:22181
First Author: Ishikawa H
Year: 1994
Journal: Mamm Genome
Title: cDNA cloning and chromosomal assignment of the mouse gene for desmoglein 3 (Dsg3), the pemphigus vulgaris antigen.
Volume: 5
Issue: 12
Pages: 803-4
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Publication
7959727 | J:18927
First Author: Buxton RS
Year: 1994
Journal: Genomics
Title: Mouse desmocollin (Dsc3) and desmoglein (Dsg1) genes are closely linked in the proximal region of chromosome 18.
Volume: 21
Issue: 3
Pages: 510-6
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Publication
16303847 | J:105610
First Author: Garrod DR
Year: 2005
Journal: J Cell Sci
Title: Hyper-adhesion in desmosomes: its regulation in wound healing and possible relationship to cadherin crystal structure.
Volume: 118
Issue: Pt 24
Pages: 5743-54
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Publication
9864371 | J:51903
First Author: Gallicano GI
Year: 1998
Journal: J Cell Biol
Title: Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage.
Volume: 143
Issue: 7
Pages: 2009-22
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Publication
12724416 | J:83058
First Author: Ciani L
Year: 2003
Journal: Mol Cell Biol
Title: Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.
Volume: 23
Issue: 10
Pages: 3575-82
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Publication
14673151 | J:87593
First Author: Cheng X
Year: 2004
Journal: Mol Cell Biol
Title: Assessment of splice variant-specific functions of desmocollin 1 in the skin.
Volume: 24
Issue: 1
Pages: 154-63
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Publication
16418220 | J:105239
First Author: Den Z
Year: 2006
Journal: J Cell Sci
Title: Desmocollin 3 is required for pre-implantation development of the mouse embryo.
Volume: 119
Issue: Pt 3
Pages: 482-9
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Publication
15775979 | J:97223
First Author: Tunggal JA
Year: 2005
Journal: EMBO J
Title: E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions.
Volume: 24
Issue: 6
Pages: 1146-56
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Publication
11781569 | J:73084
First Author: Vasioukhin V
Year: 2001
Journal: Nat Cell Biol
Title: Desmoplakin is essential in epidermal sheet formation.
Volume: 3
Issue: 12
Pages: 1076-85
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Publication
9847250 | J:51129
First Author: Bierkamp C
Year: 1999
Journal: Development
Title: Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice.
Volume: 126
Issue: 2
Pages: 371-81
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Publication
29913133 | J:309667
First Author: Kousa YA
Year: 2018
Journal: J Invest Dermatol
Title: IRF6 and AP2A Interaction Regulates Epidermal Development.
Volume: 138
Issue: 12
Pages: 2578-2588
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Publication
30689641 | J:272423
First Author: Choi YJ
Year: 2019
Journal: PLoS Genet
Title: RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.
Volume: 15
Issue: 1
Pages: e1007914
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Publication
23271346 | J:192592
First Author: Sotiropoulou PA
Year: 2013
Journal: Genes Dev
Title: BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.
Volume: 27
Issue: 1
Pages: 39-51
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Publication
18809908 | J:144091
First Author: Tinkle CL
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity.
Volume: 105
Issue: 40
Pages: 15405-10
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Publication
17130451 | J:118301
First Author: Patel S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition.
Volume: 103
Issue: 49
Pages: 18668-73
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Publication
32546759 | J:293699
First Author: Lin JI
Year: 2020
Journal: Commun Biol
Title: Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.
Volume: 3
Issue: 1
Pages: 312
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Publication
23260145 | J:193325
First Author: Boj SF
Year: 2012
Journal: Cell
Title: Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.
Volume: 151
Issue: 7
Pages: 1595-607
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:345476
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
31872082 | J:285432
 
First Author: Hamada Y
Year: 2020
Journal: Biochem Biophys Rep
Title: G790del mutation in DSC2 alone is insufficient to develop the pathogenesis of ARVC in a mouse model.
Volume: 21
Pages: 100711
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Allele
Dsc2<em1Smoc> | MGI:7289402
Name: desmocollin 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
25078903 | -
First Author: Tong Z
Year: 2014
Journal: Mol Cell Proteomics
Title: Identification of candidate substrates for the Golgi Tul1 E3 ligase using quantitative diGly proteomics in yeast.
Volume: 13
Issue: 11
Pages: 2871-82
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Publication
31368600 | -
First Author: Schmidt O
Year: 2019
Journal: EMBO J
Title: Endosome and Golgi-associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism.
Volume: 38
Issue: 15
Pages: e101433
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Protein Domain
IPR019413 | Dsc3_ub-like_dom
Type: Domain
Description: This is the N-terminal ubiquitin-like domain of DSC E3 ubiquitin ligase complex subunit 3 (Dsc3). Dsc3 is a component of the DSC E3 ubiquitin ligase complex (a Golgi-specific protein ubiquitination system) that functions in protein homeostasis under non-stress conditions, playing a role in protein quality control through endosome and Golgi-associated degradation pathway (EGAD) which targets membrane proteins at Golgi and endosomes for degradation by cytosolic proteasomes [, , ]. Dsc3 is also involved in endocytic protein trafficking [].Yeast DSC E3 ubiquitin ligase complex is the homologue of Hrd1 E3 ligase complex from mammals, in which Dsc1, Dsc2 and Dsc3 corresponds to Hrd1, Der1, and Usa1, respectively. Dsc3 is a Herp-like protein that acts as a bridge between Dsc1 and Dsc2 for their interaction [].
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Protein Domain
IPR025390 | Dsc3_C
Type: Domain
Description: This is the C-terminal domain of DSC E3 ubiquitin ligase complex subunit 3 (Dsc3), which contains two transmembrane helices and a characteristic GFDRL sequence motif. Dsc3 is a component of the DSC E3 ubiquitin ligase complex (a Golgi-specific protein ubiquitination system) that functions in protein homeostasis under non-stress conditions, playing a role in protein quality control through endosome and Golgi-associated degradation pathway (EGAD) which targets membrane proteins at Golgi and endosomes for degradation by cytosolic proteasomes [, , ]. Dsc3 is also involved in endocytic protein trafficking [].Yeast DSC E3 ubiquitin ligase complex is the homologue of Hrd1 E3 ligase complex from mammals, in which Dsc1, Dsc2 and Dsc3 corresponds to Hrd1, Der1, and Usa1, respectively. Dsc3 is a Herp-like protein that acts as a bridge between Dsc1 and Dsc2 for their interaction [].
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Protein Domain
IPR045226 | Dsc3
Type: Family
Description: This entry represents DSC E3 ubiquitin ligase complex subunit 3 (Dsc3), a component of the DSC E3 ubiquitin ligase complex (a Golgi-specific protein ubquitination system) that functions in protein homeostasis under non-stress conditions, playing a role in protein quality control through endosome and Golgi-associated degradation pathway (EGAD) which targets membrane proteins at Golgi and endosomes for degradation by cytosolic proteasomes [, , ]. Dsc3 is also involved in endocytic protein trafficking []. Dsc3 has an ubiquitin-like domain and two C-terminal transmembrane regions.Yeast DSC E3 ubiquitin ligase complex is the homologue of Hrd1 E3 ligase complex from mammals, in which Dsc1, Dsc2 and Dsc3 corresponds to Hrd1, Der1, and Usa1, respectively. Dsc3 is a Herp-like protein that acts as a bridge between Dsc1 and Dsc2 for their interaction [].
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Publication
21777356 | -
First Author: Arlt H
Year: 2011
Journal: Traffic
Title: An overexpression screen in Saccharomyces cerevisiae identifies novel genes that affect endocytic protein trafficking.
Volume: 12
Issue: 11
Pages: 1592-603
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Publication
21504829 | -
First Author: Stewart EV
Year: 2011
Journal: Mol Cell
Title: Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.
Volume: 42
Issue: 2
Pages: 160-71
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Publication
29355480 | -
   
First Author: Yang X
Year: 2018
Journal: Elife
Title: Sorting of a multi-subunit ubiquitin ligase complex in the endolysosome system.
Volume: 7
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Publication
15739220 | J:104624
First Author: Johns SA
Year: 2005
Journal: Dev Dyn
Title: Foxn1 is required for tissue assembly and desmosomal cadherin expression in the hair shaft.
Volume: 232
Issue: 4
Pages: 1062-8
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Publication
9074502 | J:39723
First Author: Marsden MD
Year: 1997
Journal: Gene
Title: Cloning and transcriptional analysis of the promoter of the human type 2 desmocollin gene (DSC2).
Volume: 186
Issue: 2
Pages: 237-47
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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