Type |
Details |
Score |
Publication |
First Author: |
Wu Z |
Year: |
2015 |
Journal: |
Cell Stem Cell |
Title: |
TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells. |
Volume: |
17 |
Issue: |
1 |
Pages: |
47-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Su Z |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner. |
Volume: |
115 |
Issue: |
32 |
Pages: |
E7522-E7531 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hao HX |
Year: |
2012 |
Journal: |
Nature |
Title: |
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. |
Volume: |
485 |
Issue: |
7397 |
Pages: |
195-200 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
171
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
123
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
224
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
204
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
164
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
154
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
77
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Culi J |
Year: |
2003 |
Journal: |
Cell |
Title: |
Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila. |
Volume: |
112 |
Issue: |
3 |
Pages: |
343-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shinada K |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
RNF43 interacts with NEDL1 and regulates p53-mediated transcription. |
Volume: |
404 |
Issue: |
1 |
Pages: |
143-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ryland GL |
Year: |
2013 |
Journal: |
J Pathol |
Title: |
RNF43 is a tumour suppressor gene mutated in mucinous tumours of the ovary. |
Volume: |
229 |
Issue: |
3 |
Pages: |
469-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Serra S |
Year: |
2018 |
Journal: |
J Clin Pathol |
Title: |
Rnf43. |
Volume: |
71 |
Issue: |
1 |
Pages: |
1-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Giannakis M |
Year: |
2014 |
Journal: |
Nat Genet |
Title: |
RNF43 is frequently mutated in colorectal and endometrial cancers. |
Volume: |
46 |
Issue: |
12 |
Pages: |
1264-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
LRP chaperone MESD (also known as mesoderm development candidate 2) represents a set of highly conserved proteins found from nematodes to humans. It is a chaperone that specifically assists with the folding of β-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). It also acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway and is essential for specification of embryonic polarity and mesoderm induction []. The Drosophila homologue, known as boca, is an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members [].The final C-terminal residues, KEDL, are the endoplasmic reticulum retention sequence as it is an ER protein specifically required for the intracellular trafficking of members of the low-density lipoprotein family of receptors (LDLRs) []. The N- and C-terminal sequences are predicted to adopt a random coil conformation, with the exception of an isolated predicted helix within the N-terminal region, The central folded domain flanked by natively unstructured regions is the necessary structure for facilitating maturation of LRP6 (Low-Density Lipoprotein Receptor-Related Protein 6 Maturation) []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the RING-type zinc finger domain of E3 ubiquitin-protein ligase RNF43. Proteins containing this domain are found in vertebrates. RNF43 acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6 [, , ]. RNF43 also interacts with NEDD-4-like ubiquitin-protein ligase-1 (NEDL1) and regulates p53-mediated transcription []. It may also be involved in cell growth control potentially through the interaction with, a chromatin-associated protein interfacing the nuclear envelope []. Mutations of RNF43 have been identified in various tumours, including colorectal cancer (CRC), endometrial cancer, mucinous ovarian tumours, gastric adenocarcinoma, pancreatic ductal adenocarcinoma, liver fluke-associated cholangiocarcinoma, hepatocellular carcinoma, and glioma [, , ]. RNF43 contains an N-terminal signal peptide, a protease-associated (PA) domain, a transmembrane (TM) domain and a C3H2C3-type RING-H2 finger domain followed by a long C-terminal region [].In frogs (Xenopus), ZNRF3 and RNF43 were seen to play a key role in limb specification, constituting a master switch along with RSPO2, which may have implications for regenerative medicine []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Carmon KS |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. |
Volume: |
108 |
Issue: |
28 |
Pages: |
11452-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Das S |
Year: |
2015 |
Journal: |
Development |
Title: |
Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche. |
Volume: |
142 |
Issue: |
12 |
Pages: |
2147-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meo Burt P |
Year: |
2018 |
Journal: |
Endocrinology |
Title: |
FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2. |
Volume: |
159 |
Issue: |
6 |
Pages: |
2386-2396 |
|
•
•
•
•
•
|
Publication |
First Author: |
Landskroner-Eiger S |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling. |
Volume: |
112 |
Issue: |
41 |
Pages: |
12812-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nordberg RC |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
LRP receptors in chondrocytes are modulated by simulated microgravity and cyclic hydrostatic pressure. |
Volume: |
14 |
Issue: |
10 |
Pages: |
e0223245 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng SL |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Msx2 exerts bone anabolism via canonical Wnt signaling. |
Volume: |
283 |
Issue: |
29 |
Pages: |
20505-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carpenter AC |
Year: |
2015 |
Journal: |
Development |
Title: |
Wnt ligands from the embryonic surface ectoderm regulate 'bimetallic strip' optic cup morphogenesis in mouse. |
Volume: |
142 |
Issue: |
5 |
Pages: |
972-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park K |
Year: |
2011 |
Journal: |
Mol Cell Biol |
Title: |
Identification of a novel inhibitor of the canonical Wnt pathway. |
Volume: |
31 |
Issue: |
14 |
Pages: |
3038-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SP |
Year: |
2019 |
Journal: |
J Biol Chem |
Title: |
Lrp4 expression by adipocytes and osteoblasts differentially impacts sclerostin's endocrine effects on body composition and glucose metabolism. |
Volume: |
294 |
Issue: |
17 |
Pages: |
6899-6911 |
|
•
•
•
•
•
|
Publication |
First Author: |
Phillips MD |
Year: |
2011 |
Journal: |
Int J Cardiol |
Title: |
Dkk1 and Dkk2 regulate epicardial specification during mouse heart development. |
Volume: |
150 |
Issue: |
2 |
Pages: |
186-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson KK |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Molecular determinants of WNT9b responsiveness in nephron progenitor cells. |
Volume: |
14 |
Issue: |
4 |
Pages: |
e0215139 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jimbo K |
Year: |
2022 |
Journal: |
Leukemia |
Title: |
Immunoglobulin superfamily member 8 maintains myeloid leukemia stem cells through inhibition of β-catenin degradation. |
Volume: |
36 |
Issue: |
6 |
Pages: |
1550-1562 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu L |
Year: |
2014 |
Journal: |
Mol Biol Cell |
Title: |
RNA-binding protein HuR promotes growth of small intestinal mucosa by activating the Wnt signaling pathway. |
Volume: |
25 |
Issue: |
21 |
Pages: |
3308-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bryja V |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. |
Volume: |
104 |
Issue: |
16 |
Pages: |
6690-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang MK |
Year: |
2014 |
Journal: |
J Bone Miner Res |
Title: |
Reversing LRP5-dependent osteoporosis and SOST deficiency-induced sclerosing bone disorders by altering WNT signaling activity. |
Volume: |
29 |
Issue: |
1 |
Pages: |
29-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu Y |
Year: |
2013 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Pathogenic role of the Wnt signaling pathway activation in laser-induced choroidal neovascularization. |
Volume: |
54 |
Issue: |
1 |
Pages: |
141-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng R |
Year: |
2016 |
Journal: |
Diabetes |
Title: |
Interaction of PPARα With the Canonic Wnt Pathway in the Regulation of Renal Fibrosis. |
Volume: |
65 |
Issue: |
12 |
Pages: |
3730-3743 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berendsen AD |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Modulation of canonical Wnt signaling by the extracellular matrix component biglycan. |
Volume: |
108 |
Issue: |
41 |
Pages: |
17022-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ureña-Peralta JR |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Deep sequencing and miRNA profiles in alcohol-induced neuroinflammation and the TLR4 response in mice cerebral cortex. |
Volume: |
8 |
Issue: |
1 |
Pages: |
15913 |
|
•
•
•
•
•
|
Publication |
First Author: |
Semënov MV |
Year: |
2001 |
Journal: |
Curr Biol |
Title: |
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. |
Volume: |
11 |
Issue: |
12 |
Pages: |
951-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
von Marschall Z |
Year: |
2010 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling. |
Volume: |
400 |
Issue: |
3 |
Pages: |
299-304 |
|
•
•
•
•
•
|
Publication |
First Author: |
Holmen SL |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling. |
Volume: |
277 |
Issue: |
38 |
Pages: |
34727-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2006 |
Journal: |
Bone |
Title: |
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. |
Volume: |
39 |
Issue: |
4 |
Pages: |
754-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2010 |
Journal: |
Oncogene |
Title: |
Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: implication for breast cancer tumorigenesis. |
Volume: |
29 |
Issue: |
4 |
Pages: |
539-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Honda T |
Year: |
2010 |
Journal: |
Mol Biol Cell |
Title: |
PDZRN3 negatively regulates BMP-2-induced osteoblast differentiation through inhibition of Wnt signaling. |
Volume: |
21 |
Issue: |
18 |
Pages: |
3269-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei W |
Year: |
2012 |
Journal: |
Mol Cell Biol |
Title: |
The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein. |
Volume: |
32 |
Issue: |
19 |
Pages: |
3903-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fei C |
Year: |
2013 |
Journal: |
Mol Cell Biol |
Title: |
Smurf1-mediated Lys29-linked nonproteolytic polyubiquitination of axin negatively regulates Wnt/β-catenin signaling. |
Volume: |
33 |
Issue: |
20 |
Pages: |
4095-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu J |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. |
Volume: |
110 |
Issue: |
50 |
Pages: |
20224-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schafer ST |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
The Wnt adaptor protein ATP6AP2 regulates multiple stages of adult hippocampal neurogenesis. |
Volume: |
35 |
Issue: |
12 |
Pages: |
4983-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chin EN |
Year: |
2015 |
Journal: |
Mol Cell Biol |
Title: |
Lrp5 Has a Wnt-Independent Role in Glucose Uptake and Growth for Mammary Epithelial Cells. |
Volume: |
36 |
Issue: |
6 |
Pages: |
871-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khan SK |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Induced GnasR201H expression from the endogenous Gnas locus causes fibrous dysplasia by up-regulating Wnt/β-catenin signaling. |
Volume: |
115 |
Issue: |
3 |
Pages: |
E418-E427 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerlach JP |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
TMEM59 potentiates Wnt signaling by promoting signalosome formation. |
Volume: |
115 |
Issue: |
17 |
Pages: |
E3996-E4005 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nayak G |
Year: |
2018 |
Journal: |
Development |
Title: |
Developmental vascular regression is regulated by a Wnt/β-catenin, MYC and CDKN1A pathway that controls cell proliferation and cell death. |
Volume: |
145 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lian G |
Year: |
2019 |
Journal: |
Cereb Cortex |
Title: |
Formin 2 Regulates Lysosomal Degradation of Wnt-Associated β-Catenin in Neural Progenitors. |
Volume: |
29 |
Issue: |
5 |
Pages: |
1938-1952 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stypulkowski E |
Year: |
2021 |
Journal: |
J Biol Chem |
Title: |
Rab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes. |
Volume: |
296 |
|
Pages: |
100488 |
|
•
•
•
•
•
|
Publication |
First Author: |
Palsgaard J |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5). |
Volume: |
287 |
Issue: |
15 |
Pages: |
12016-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhat N |
Year: |
2022 |
Journal: |
FASEB J |
Title: |
TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk. |
Volume: |
36 |
Issue: |
3 |
Pages: |
e22185 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koo BK |
Year: |
2012 |
Journal: |
Nature |
Title: |
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. |
Volume: |
488 |
Issue: |
7413 |
Pages: |
665-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sugiura T |
Year: |
2008 |
Journal: |
Exp Cell Res |
Title: |
A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95. |
Volume: |
314 |
Issue: |
7 |
Pages: |
1519-28 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
172
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Moosa S |
Year: |
2019 |
Journal: |
Am J Hum Genet |
Title: |
Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta. |
Volume: |
105 |
Issue: |
4 |
Pages: |
836-843 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan KS |
Year: |
2017 |
Journal: |
Nature |
Title: |
Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal. |
Volume: |
545 |
Issue: |
7653 |
Pages: |
238-242 |
|
•
•
•
•
•
|
Publication |
First Author: |
MacDonald BT |
Year: |
2007 |
Journal: |
Bone |
Title: |
Bone mass is inversely proportional to Dkk1 levels in mice. |
Volume: |
41 |
Issue: |
3 |
Pages: |
331-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi HY |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo. |
Volume: |
4 |
Issue: |
11 |
Pages: |
e7930 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1597
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1877
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
774
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1535
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the RING-type zinc finger domain of E3 ubiquitin-protein ligase ZNRF3 (Zinc/RING finger protein 3), a transmembrane enzyme () homologue of Ring finger protein 43 (RNF43). It is predominantly found in vertebrates.In humans, ZNRF3 acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6 [, , ]. ZNRF3 also functions as a tumour suppressor in the intestinal stem cell zone by restricting the size of the intestinal stem cell zone []. In frogs (Xenopus), ZNRF3 and RNF43 were seen to play a key role in limb specification, constituting a master switch along with RSPO2, which may have implications for regenerative medicine []. Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. Some of these domains bind zinc, but many do not; instead binding other metals such as iron, or no metal at all. For example, some family members form salt bridges to stabilise the finger-like folds. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis (African clawed frog), however they are now recognised to bind DNA, RNA, protein and/or lipid substrates [, , , , ]. Their binding properties depend on the amino acid sequence of the finger domains and of the linker between fingers, as well as on the higher-order structures and the number of fingers. Znf domains are often found in clusters, where fingers can have different binding specificities. There are many superfamilies of Znf motifs, varying in both sequence and structure. They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. For example, Znf-containing proteins function in gene transcription, translation, mRNA trafficking, cytoskeleton organisation, epithelial development, cell adhesion, protein folding, chromatin remodelling and zinc sensing, to name but a few []. Zinc-binding motifs are stable structures, and they rarely undergo conformational changes upon binding their target. |
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•
•
•
•
•
|
Publication |
First Author: |
Szenker-Ravi E |
Year: |
2018 |
Journal: |
Nature |
Title: |
RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. |
Volume: |
557 |
Issue: |
7706 |
Pages: |
564-569 |
|
•
•
•
•
•
|
Publication |
First Author: |
Støle TP |
Year: |
2022 |
Journal: |
Front Cell Dev Biol |
Title: |
The female syndecan-4-/- heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels. |
Volume: |
10 |
|
Pages: |
908126 |
|
•
•
•
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•
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Publication |
First Author: |
Lai KKY |
Year: |
2017 |
Journal: |
Gastroenterology |
Title: |
Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6. |
Volume: |
152 |
Issue: |
6 |
Pages: |
1477-1491 |
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•
•
•
•
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Publication |
First Author: |
Tuo J |
Year: |
2015 |
Journal: |
J Transl Med |
Title: |
Wnt signaling in age-related macular degeneration: human macular tissue and mouse model. |
Volume: |
13 |
|
Pages: |
330 |
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•
•
•
•
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Publication |
First Author: |
Wang D |
Year: |
2013 |
Journal: |
Genes Dev |
Title: |
Structural basis for R-spondin recognition by LGR4/5/6 receptors. |
Volume: |
27 |
Issue: |
12 |
Pages: |
1339-44 |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
784
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
657
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
743
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
249
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
424
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
415
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
459
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
265
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
913
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
265
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
430
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
461
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
448
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
422
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
424
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
390
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
442
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1614
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1613
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1614
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1639
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1613
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Matthews JM |
Year: |
2002 |
Journal: |
IUBMB Life |
Title: |
Zinc fingers--folds for many occasions. |
Volume: |
54 |
Issue: |
6 |
Pages: |
351-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gamsjaeger R |
Year: |
2007 |
Journal: |
Trends Biochem Sci |
Title: |
Sticky fingers: zinc-fingers as protein-recognition motifs. |
Volume: |
32 |
Issue: |
2 |
Pages: |
63-70 |
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•
•
•
•
•
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Publication |
First Author: |
Hall TM |
Year: |
2005 |
Journal: |
Curr Opin Struct Biol |
Title: |
Multiple modes of RNA recognition by zinc finger proteins. |
Volume: |
15 |
Issue: |
3 |
Pages: |
367-73 |
|
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•
•
•
•
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Publication |
First Author: |
Brown RS |
Year: |
2005 |
Journal: |
Curr Opin Struct Biol |
Title: |
Zinc finger proteins: getting a grip on RNA. |
Volume: |
15 |
Issue: |
1 |
Pages: |
94-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klug A |
Year: |
1999 |
Journal: |
J Mol Biol |
Title: |
Zinc finger peptides for the regulation of gene expression. |
Volume: |
293 |
Issue: |
2 |
Pages: |
215-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Laity JH |
Year: |
2001 |
Journal: |
Curr Opin Struct Biol |
Title: |
Zinc finger proteins: new insights into structural and functional diversity. |
Volume: |
11 |
Issue: |
1 |
Pages: |
39-46 |
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•
•
•
•
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