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Search results 2701 to 2800 out of 7122 for App

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Type Details Score
Publication  
First Author: Ng CAS
Year: 2022
Journal: Neurobiol Dis
Title: Chemotherapy promotes astrocytic response to Aβ deposition, but not Aβ levels, in a mouse model of amyloid and APOE.
Volume: 175
Pages: 105915
Publication
First Author: Lee S
Year: 2023
Journal: Cell Rep
Title: APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge.
Volume: 42
Issue: 3
Pages: 112196
Publication  
First Author: Balu D
Year: 2023
Journal: Front Aging Neurosci
Title: APOE genotype and sex modulate Alzheimer's disease pathology in aged EFAD transgenic mice.
Volume: 15
Pages: 1279343
Publication
First Author: Crivelli SM
Year: 2020
Journal: Sci Rep
Title: Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe.
Volume: 10
Issue: 1
Pages: 19354
Publication
First Author: Wang N
Year: 2024
Journal: iScience
Title: Microglial apolipoprotein E particles contribute to neuronal senescence and synaptotoxicity.
Volume: 27
Issue: 6
Pages: 110006
Publication  
First Author: Cacciottolo M
Year: 2016
Journal: Neurobiol Aging
Title: The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice.
Volume: 37
Pages: 47-57
Publication
First Author: Maldonado Weng J
Year: 2019
Journal: Mol Neurodegener
Title: Synergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice.
Volume: 14
Issue: 1
Pages: 47
Publication
First Author: Christensen A
Year: 2019
Journal: FASEB J
Title: APOE genotype affects metabolic and Alzheimer-related outcomes induced by Western diet in female EFAD mice.
Volume: 33
Issue: 3
Pages: 4054-4066
Publication
First Author: Berkowitz BA
Year: 2017
Journal: FASEB J
Title: In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome.
Volume: 31
Issue: 9
Pages: 4179-4186
Publication
First Author: Blanchard JW
Year: 2020
Journal: Nat Med
Title: Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.
Volume: 26
Issue: 6
Pages: 952-963
Publication
First Author: Campagna J
Year: 2018
Journal: Sci Rep
Title: A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.
Volume: 8
Issue: 1
Pages: 17574
Publication  
First Author: Xiong M
Year: 2021
Journal: Sci Transl Med
Title: APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function.
Volume: 13
Issue: 581
Publication  
First Author: Ballasch I
Year: 2023
Journal: Brain Behav Immun
Title: Ikzf1 as a novel regulator of microglial homeostasis in inflammation and neurodegeneration.
Volume: 109
Pages: 144-161
Publication  
First Author: Eckman J
Year: 2018
Journal: Nutrients
Title: Oxidative Stress Levels in the Brain Are Determined by Post-Mortem Interval and Ante-Mortem Vitamin C State but Not Alzheimer's Disease Status.
Volume: 10
Issue: 7
Publication
First Author: Ye B
Year: 2015
Journal: Glia
Title: Dual pathways mediate β-amyloid stimulated glutathione release from astrocytes.
Volume: 63
Issue: 12
Pages: 2208-19
Publication  
First Author: Gutiérrez IL
Year: 2022
Journal: Int J Mol Sci
Title: CCL2 Inhibition of Pro-Resolving Mediators Potentiates Neuroinflammation in Astrocytes.
Volume: 23
Issue: 6
Publication
First Author: Sasner M
Year: 2024
Journal: Alzheimers Dement
Title: In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Volume: 20
Issue: 7
Pages: 4970-4984
Publication
First Author: Chen Y
Year: 2024
Journal: iScience
Title: A cingulate-hippocampal circuit mediates early depressive-like behavior in the mouse model of Alzheimer disease.
Volume: 27
Issue: 5
Pages: 109778
Publication
First Author: Adaikkan C
Year: 2022
Journal: Neuron
Title: Alterations in a cross-hemispheric circuit associates with novelty discrimination deficits in mouse models of neurodegeneration.
Volume: 110
Issue: 19
Pages: 3091-3105.e9
Publication
First Author: Kim S
Year: 2020
Journal: Sci Adv
Title: Dynamic Fas signaling network regulates neural stem cell proliferation and memory enhancement.
Volume: 6
Issue: 17
Pages: eaaz9691
Publication  
First Author: Da Mesquita S
Year: 2021
Journal: Sci Adv
Title: Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology.
Volume: 7
Issue: 21
Publication
First Author: Storck SE
Year: 2016
Journal: J Clin Invest
Title: Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier.
Volume: 126
Issue: 1
Pages: 123-36
Publication  
First Author: Cheng J
Year: 2021
Journal: Sci Adv
Title: Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology.
Volume: 7
Issue: 35
Publication
First Author: Xia Y
Year: 2022
Journal: Sci Adv
Title: Neuronal C/EBPβ/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression.
Volume: 8
Issue: 13
Pages: eabj8658
Publication  
First Author: Aparicio N
Year: 2018
Journal: Biochem Pharmacol
Title: Role of interleukin 1-beta in the inflammatory response in a fatty acid amide hydrolase-knockout mouse model of Alzheimer's disease.
Volume: 157
Pages: 202-209
Publication
First Author: Vázquez C
Year: 2015
Journal: Neurobiol Aging
Title: Endocannabinoid regulation of amyloid-induced neuroinflammation.
Volume: 36
Issue: 11
Pages: 3008-3019
Publication
First Author: Ruiz-Pérez G
Year: 2021
Journal: J Neuroinflammation
Title: Potentiation of amyloid beta phagocytosis and amelioration of synaptic dysfunction upon FAAH deletion in a mouse model of Alzheimer's disease.
Volume: 18
Issue: 1
Pages: 223
Publication  
First Author: Islam J
Year: 2022
Journal: Front Immunol
Title: GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 766919
Publication
First Author: Dong Y
Year: 2021
Journal: Commun Biol
Title: The anesthetic sevoflurane induces tau trafficking from neurons to microglia.
Volume: 4
Issue: 1
Pages: 560
Publication
First Author: Nakano-Kobayashi A
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Astrocyte-targeting therapy rescues cognitive impairment caused by neuroinflammation via the Nrf2 pathway.
Volume: 120
Issue: 33
Pages: e2303809120
Publication  
First Author: Zou Y
Year: 2021
Journal: Front Cell Dev Biol
Title: Programmed Cell Death Protein 1 Blockade Reduces Glycogen Synthase Kinase 3β Activity and Tau Hyperphosphorylation in Alzheimer's Disease Mouse Models.
Volume: 9
Pages: 769229
Publication  
First Author: Volkman R
Year: 2019
Journal: Front Neurosci
Title: Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 990
Publication
First Author: Wang S
Year: 2022
Journal: Cell
Title: TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways.
Volume: 185
Issue: 22
Pages: 4153-4169.e19
Publication
First Author: Dong X
Year: 2023
Journal: J Neuroinflammation
Title: Ogt-mediated O-GlcNAcylation inhibits astrocytes activation through modulating NF-κB signaling pathway.
Volume: 20
Issue: 1
Pages: 146
Publication      
First Author: Taha HB
Year: 2024
Journal: Geroscience
Title: Activation of the muscle-to-brain axis ameliorates neurocognitive deficits in an Alzheimer's disease mouse model via enhancing neurotrophic and synaptic signaling.
Publication
First Author: Kim N
Year: 2023
Journal: J Neuroinflammation
Title: Inhibition of microfold cells ameliorates early pathological phenotypes by modulating microglial functions in Alzheimer's disease mouse model.
Volume: 20
Issue: 1
Pages: 282
Publication
First Author: Saeki K
Year: 2024
Journal: Nat Immunol
Title: IRF8 defines the epigenetic landscape in postnatal microglia, thereby directing their transcriptome programs.
Volume: 25
Issue: 10
Pages: 1928-1942
Publication
First Author: Lee J
Year: 2020
Journal: Aging Cell
Title: Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease.
Volume: 19
Issue: 2
Pages: e13078
Publication
First Author: Lee J
Year: 2023
Journal: Nat Commun
Title: ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.
Volume: 14
Issue: 1
Pages: 8463
Publication
First Author: Moutinho M
Year: 2022
Journal: Sci Transl Med
Title: The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.
Volume: 14
Issue: 637
Pages: eabl7634
Publication
First Author: Kozyrev N
Year: 2020
Journal: J Neuropathol Exp Neurol
Title: Infiltrating Hematogenous Macrophages Aggregate Around β-Amyloid Plaques in an Age- and Sex-Dependent Manner in a Mouse Model of Alzheimer Disease.
Volume: 79
Issue: 11
Pages: 1147-1162
Publication
First Author: Bhatia HS
Year: 2022
Journal: Cell
Title: Spatial proteomics in three-dimensional intact specimens.
Volume: 185
Issue: 26
Pages: 5040-5058.e19
Publication
First Author: Kolabas ZI
Year: 2023
Journal: Cell
Title: Distinct molecular profiles of skull bone marrow in health and neurological disorders.
Volume: 186
Issue: 17
Pages: 3706-3725.e29
Publication  
First Author: Dukhinova M
Year: 2019
Journal: Neurobiol Aging
Title: Fresh evidence for major brain gangliosides as a target for the treatment of Alzheimer's disease.
Volume: 77
Pages: 128-143
Publication
First Author: Griciuc A
Year: 2019
Journal: Neuron
Title: TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.
Volume: 103
Issue: 5
Pages: 820-835.e7
Publication  
First Author: Gnoth K
Year: 2022
Journal: Biomolecules
Title: Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice.
Volume: 12
Issue: 3
Publication
First Author: Petrov AM
Year: 2019
Journal: FASEB J
Title: The key genes, phosphoproteins, processes, and pathways affected by efavirenz-activated CYP46A1 in the amyloid-decreasing paradigm of efavirenz treatment.
Volume: 33
Issue: 8
Pages: 8782-8798
Publication  
First Author: Liu Y
Year: 2024
Journal: J Neurosci
Title: Imbalance in Glucose Metabolism Regulates the Transition of Microglia from Homeostasis to Disease-Associated Microglia Stage 1.
Volume: 44
Issue: 20
Publication
First Author: Stoyanov S
Year: 2021
Journal: Glia
Title: Attenuation of the extracellular matrix restores microglial activity during the early stage of amyloidosis.
Volume: 69
Issue: 1
Pages: 182-200
Publication
First Author: Baik SH
Year: 2016
Journal: Glia
Title: Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model.
Volume: 64
Issue: 12
Pages: 2274-2290
Publication  
First Author: Liu J
Year: 2023
Journal: eNeuro
Title: Prevention of Alzheimer Pathology by Blocking Neuregulin Signaling on Microglia.
Volume: 10
Issue: 11
Publication  
First Author: Gyoneva S
Year: 2016
Journal: Neuroscience
Title: Altered motility of plaque-associated microglia in a model of Alzheimer's disease.
Volume: 330
Pages: 410-20
Publication
First Author: Zhou T
Year: 2022
Journal: Nat Commun
Title: Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice.
Volume: 13
Issue: 1
Pages: 6233
Publication
First Author: Le LHD
Year: 2024
Journal: Sci Rep
Title: Partial microglial depletion and repopulation exert subtle but differential effects on amyloid pathology at different disease stages.
Volume: 14
Issue: 1
Pages: 30912
Publication
First Author: Wang Y
Year: 2015
Journal: Cell
Title: TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
Volume: 160
Issue: 6
Pages: 1061-71
Publication  
First Author: Wendt S
Year: 2022
Journal: Redox Biol
Title: Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress.
Volume: 56
Pages: 102448
Publication
First Author: Baik SH
Year: 2019
Journal: Cell Metab
Title: A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease.
Volume: 30
Issue: 3
Pages: 493-507.e6
Publication
First Author: Puntambekar SS
Year: 2022
Journal: Mol Neurodegener
Title: CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease.
Volume: 17
Issue: 1
Pages: 47
Publication  
First Author: Choi C
Year: 2023
Journal: Life Sci Alliance
Title: DSCR1 deficiency ameliorates the Aβ pathology of Alzheimer's disease by enhancing microglial activity.
Volume: 6
Issue: 2
Publication  
First Author: Barrett T
Year: 2019
Journal: Neuroscience
Title: p35 Hemizygous Deletion in 5xFAD Mice Increases Aβ Plaque Load in Males but Not in Females.
Volume: 417
Pages: 45-56
Publication
First Author: Mishra P
Year: 2023
Journal: Cell Rep
Title: Rescue of Alzheimer's disease phenotype in a mouse model by transplantation of wild-type hematopoietic stem and progenitor cells.
Volume: 42
Issue: 8
Pages: 112956
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication  
First Author: Kumar S
Year: 2023
Journal: JCI Insight
Title: Role of the caspase-8/RIPK3 axis in Alzheimer's disease pathogenesis and Aβ-induced NLRP3 inflammasome activation.
Volume: 8
Issue: 3
Publication
First Author: Gowrishankar S
Year: 2017
Journal: J Cell Biol
Title: Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology.
Volume: 216
Issue: 10
Pages: 3291-3305
Publication
First Author: Paouri E
Year: 2017
Journal: J Neurosci
Title: Peripheral Tumor Necrosis Factor-Alpha (TNF-α) Modulates Amyloid Pathology by Regulating Blood-Derived Immune Cells and Glial Response in the Brain of AD/TNF Transgenic Mice.
Volume: 37
Issue: 20
Pages: 5155-5171
Publication
First Author: Lin PB
Year: 2023
Journal: Alzheimers Dement
Title: INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer's disease.
Volume: 19
Issue: 6
Pages: 2528-2537
Publication  
First Author: Beck SJ
Year: 2016
Journal: Nat Commun
Title: Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.
Volume: 7
Pages: 11483
Publication
First Author: Devi L
Year: 2013
Journal: PLoS One
Title: Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.
Volume: 8
Issue: 10
Pages: e77335
Publication  
First Author: Varbanov H
Year: 2023
Journal: Neurobiol Dis
Title: Rescue of synaptic and cognitive functions in polysialic acid-deficient mice and dementia models by short polysialic acid fragments.
Volume: 180
Pages: 106079
Publication  
First Author: Gauba E
Year: 2019
Journal: Neurobiol Dis
Title: Cyclophilin D deficiency attenuates mitochondrial F1Fo ATP synthase dysfunction via OSCP in Alzheimer's disease.
Volume: 121
Pages: 138-147
Publication
First Author: Kumar P
Year: 2024
Journal: Nat Commun
Title: Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology.
Volume: 15
Issue: 1
Pages: 2823
Publication
First Author: Park K
Year: 2024
Journal: Curr Biol
Title: Memory encoding and retrieval by retrosplenial parvalbumin interneurons are impaired in Alzheimer's disease model mice.
Volume: 34
Issue: 2
Pages: 434-443.e4
Publication  
First Author: Li H
Year: 2022
Journal: Neurobiol Aging
Title: Loss of SST and PV positive interneurons in the ventral hippocampus results in anxiety-like behavior in 5xFAD mice.
Volume: 117
Pages: 165-178
Publication
First Author: Hur JY
Year: 2020
Journal: Nature
Title: The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease.
Volume: 586
Issue: 7831
Pages: 735-740
Publication
First Author: Ali F
Year: 2019
Journal: J Alzheimers Dis
Title: Parvalbumin-Positive Neuron Loss and Amyloid-β Deposits in the Frontal Cortex of Alzheimer's Disease-Related Mice.
Volume: 72
Issue: 4
Pages: 1323-1339
Publication
First Author: Caccavano A
Year: 2020
Journal: J Neurosci
Title: Inhibitory Parvalbumin Basket Cell Activity is Selectively Reduced during Hippocampal Sharp Wave Ripples in a Mouse Model of Familial Alzheimer's Disease.
Volume: 40
Issue: 26
Pages: 5116-5136
Publication      
First Author: Bouin A
Year: 2024
Journal: Mol Psychiatry
Title: New rabies viral resources for multi-scale neural circuit mapping.
Publication
First Author: Wilson CA
Year: 2020
Journal: Sci Rep
Title: Effects of optogenetic stimulation of basal forebrain parvalbumin neurons on Alzheimer's disease pathology.
Volume: 10
Issue: 1
Pages: 15456
Publication
First Author: Tian J
Year: 2023
Journal: iScience
Title: Low-temperature resin embedding of the whole brain for various precise structures dissection.
Volume: 26
Issue: 5
Pages: 106705
Publication
First Author: Tian J
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Dissection of the long-range projections of specific neurons at the synaptic level in the whole mouse brain.
Volume: 119
Issue: 40
Pages: e2202536119
Publication  
First Author: Angel A
Year: 2020
Journal: Int J Mol Sci
Title: Caspase-6 Knockout in the 5xFAD Model of Alzheimer's Disease Reveals Favorable Outcome on Memory and Neurological Hallmarks.
Volume: 21
Issue: 3
Publication  
First Author: Herzer S
Year: 2018
Journal: Front Mol Neurosci
Title: Deletion of Specific Sphingolipids in Distinct Neurons Improves Spatial Memory in a Mouse Model of Alzheimer's Disease.
Volume: 11
Pages: 206
Publication
First Author: Walter S
Year: 2019
Journal: Acta Neuropathol
Title: The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease.
Volume: 137
Issue: 2
Pages: 239-257
Publication  
First Author: Tian J
Year: 2019
Journal: Sci Transl Med
Title: Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer's disease.
Volume: 11
Issue: 505
Publication
First Author: Kisler K
Year: 2023
Journal: Mol Neurodegener
Title: Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier.
Volume: 18
Issue: 1
Pages: 7
Publication
First Author: Gräff J
Year: 2012
Journal: Nature
Title: An epigenetic blockade of cognitive functions in the neurodegenerating brain.
Volume: 483
Issue: 7388
Pages: 222-6
Publication
First Author: Morshed N
Year: 2020
Journal: Mol Syst Biol
Title: Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.
Volume: 16
Issue: 12
Pages: e9819
Publication
First Author: Lorenzetto E
Year: 2014
Journal: Brain Struct Funct
Title: Distribution of different isoforms of receptor protein tyrosine phosphatase γ (Ptprg-RPTP γ) in adult mouse brain: upregulation during neuroinflammation.
Volume: 219
Issue: 3
Pages: 875-90
Strain
Attribute String: transgenic, F1 hybrid
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: transgenic, F1 hybrid
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: targeted mutation, transgenic, mutant strain, congenic
Strain
Attribute String: F1 hybrid, mutant strain, transgenic
Strain
Attribute String: F1 hybrid, mutant strain, transgenic
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: F1 hybrid, mutant strain, transgenic
Strain
Attribute String: transgenic, F1 hybrid
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: F1 hybrid, mutant strain, transgenic