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Search results 1401 to 1500 out of 1596 for Fras1

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Type Details Score
GXD Expression  
Probe: MGI:5609850
Assay Type: RNA in situ
Annotation Date: 2015-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1877124
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5609965
Age: embryonic day 16.5
Note: In developing pelage hair follicles, expression in epithelial epidermal keratinocytes and in condensing mesenchymal cells.
Specimen Label: 4A
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4425638
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824920
Age: embryonic day 14.5
Image: euxassay_016475_03
Specimen Label: euxassay_016475_03
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4425638
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824920
Age: embryonic day 14.5
Image: euxassay_016475_04
Specimen Label: euxassay_016475_04
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4425638
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824920
Age: embryonic day 14.5
Image: euxassay_016475_05
Specimen Label: euxassay_016475_05
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4425638
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824920
Age: embryonic day 14.5
Image: euxassay_016475_20
Specimen Label: euxassay_016475_20
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4425638
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824920
Age: embryonic day 14.5
Image: euxassay_016475_21
Specimen Label: euxassay_016475_21
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:5609850
Assay Type: RNA in situ
Annotation Date: 2015-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3643722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5609965
Age: embryonic day 14.5
Note: Expression in mesenchymal cells surrounding branching renal epithelia. Expression in mesenchyme surrounding the ureter.
Specimen Label: 5E
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:5578503
Assay Type: Immunohistochemistry
Annotation Date: 2014-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5578504
Age: postnatal week 9
Note: Expression is at the basement membrane.
Specimen Label: 2B
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2014-08-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3573928
Stage: TS28
Assay Id: MGI:5578614
Age: postnatal week 9
Specimen Label: 2B
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6454323
Age: embryonic day 13.5
Image: 4A my/+ left
Specimen Label: 4A my/+ left
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3639221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6454323
Age: embryonic day 13.5
Image: 4A my/my left
Note: Expression reduced in my/my mice at E13.5.
Specimen Label: 4A my/my left
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6454323
Age: embryonic day 17.5
Image: 4B my/+ left
Specimen Label: 4B my/+ left
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3639225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6454323
Age: embryonic day 17.5
Image: 4B my/my left
Note: Reduction in expression more prominent at later developmental stages.
Specimen Label: 4B my/my left
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6454323
Age: postnatal newborn
Image: 4C my/+ left
Specimen Label: 4C my/+ left
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3639227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6454323
Age: postnatal newborn
Image: 4C my/my left
Note: Reduction in expression more prominent at later developmental stages.
Specimen Label: 4C my/my left
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6454323
Age: embryonic day 14.5
Image: 4D eb/+ left
Specimen Label: 4D eb/+ left
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3639222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6454323
Age: embryonic day 14.5
Image: 4D eb/eb left
Note: Expression reduced at E14.5
Specimen Label: 4D eb/eb left
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3639227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6454323
Age: postnatal newborn
Image: 4E eb/eb left
Note: Expression almost absent at birth.
Specimen Label: 4E eb/eb left
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6454323
Age: embryonic day 14.5
Image: 5G +/- left
Specimen Label: 5G +/- left
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3639222
Stage: TS22
Assay Id: MGI:6454323
Age: embryonic day 14.5
Image: 5G -/- left
Note: No expression at basement membrane zone.
Specimen Label: 5G -/- left
Detected: false
Specimen Num: 12
GXD Expression  
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6454323
Age: postnatal newborn
Image: 4E eb/+ left
Specimen Label: 4E eb/+ left
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564078
Age: embryonic day 14.5
Note: Expression is as a clustered arrangement underneath the lamina densa in two different parts of the skin. Immunogold clusters are distributed along the length of the anchoring-like fibrils that emanate from the lamina densa and extend to cells of the connective tissue. Absent in interstitial collagen fibers.
Specimen Label: 5A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564078
Age: embryonic day 14.5
Note: Expression is as a clustered arrangement underneath the lamina densa in two different parts of the skin. Immunogold clusters are distributed along the length of the anchoring-like fibrils that emanate from the lamina densa and extend to cells of the connective tissue. Absent in interstitial collagen fibers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564079
Age: embryonic day 14.5
Note: Expression is as a clustered arrangement underneath the lamina densa in two different parts of the skin. Immunogold clusters are distributed along the length of the anchoring-like fibrils that emanate from the lamina densa and extend to cells of the connective tissue. There are also localizatiosn in the lamina lucida. Absent in interstitial collagen fibers.
Specimen Label: 5D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5609850
Assay Type: RNA in situ
Annotation Date: 2015-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3261424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5609965
Age: embryonic day 16.5
Specimen Label: 1G
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7468618
Assay Type: RNA in situ
Annotation Date: 2023-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736421
Pattern: Graded
Stage: TS21
Assay Id: MGI:7468631
Age: embryonic day 13.5
Image: 2J
Note: Gradient of expression in palatal shelf mesenchyme and mandibular process.
Specimen Label: 2J
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2007-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3707472
Age: embryonic day 10.5
Image: 2B
Note: Expression is in the basement membrane.
Specimen Label: 2B
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2007-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3707570
Age: embryonic day 10.5
Image: 2D
Note: Expression is in the basement membrane.
Specimen Label: 2D
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2015-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5609958
Age: embryonic day 14.5
Note: Expression below the lamina densa, within sub-lamina densa, and in zone between lamina densa and epithelial surface. Clustereed in extracellular space coinciding with fibrillar structures from basement membrane, extending towards connective tissue.
Specimen Label: 1M
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6454325
Age: embryonic day 15.5
Image: S11A
Note: Expression in lamina densa, and in subepidermal region of dermal mesenchyme. Expression often in close proximity to that of Fras1.
Specimen Label: S11A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564017
Age: embryonic day 14.5
Note: Expression is in the epithelial basement membrane of the skin.
Specimen Label: 1B
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:7564017
Age: embryonic day 14.5
Note: Expression in the epithelial basement membrane of the skin in this mutant is absent.
Specimen Label: 2A
Detected: false
Specimen Num: 4
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564022
Age: embryonic day 14.5
Note: Expression is in the epithelial basement membrane of the skin.
Specimen Label: 1D
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564022
Age: embryonic day 14.5
Note: Expression in the epithelial basement membrane of the skin in this mutant is the same as in wild-type.
Specimen Label: 2G
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2015-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5609958
Age: embryonic day 14.5
Note: Clusters of expression in close proximity of dermal mesenchymal cells.
Specimen Label: 1N
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5609850
Assay Type: RNA in situ
Annotation Date: 2015-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3261524
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5609965
Age: embryonic day 16.5
Note: Prominent expression in skin regions correponding to developing digits.
Specimen Label: 1G
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2007-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3707472
Age: embryonic day 13.5
Image: 5J
Note: Expression is in the epithelial basement membranes.
Specimen Label: 5J
Detected: true
Specimen Num: 15
GXD Expression
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2007-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3707570
Age: embryonic day 13.5
Image: 5L
Note: Expression is in the epithelial basement membranes.
Specimen Label: 5L
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2015-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5609957
Age: embryonic day 14.5
Note: Expression in epithelial basement membranes.
Specimen Label: 5J
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2014-11-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5605078
Age: embryonic day 12.5
Note: Staining is throughout the meningeal basement membrane.
Specimen Label: 3g
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2007-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3707472
Age: embryonic day 12.5
Image: 1F
Note: Expression is in the basement membrane of the inner retinal layer.
Specimen Label: 1F
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2007-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3707570
Age: embryonic day 12.5
Image: 1H
Note: Expression is in the basement membrane of the inner retinal layer.
Specimen Label: 1H
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5578503
Assay Type: Immunohistochemistry
Annotation Date: 2014-08-25
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5578504
Age: embryonic day 14.5
Note: Expression is at the basement membrane.
Specimen Label: 2C
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3837756
Assay Type: Immunohistochemistry
Annotation Date: 2014-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5578614
Age: embryonic day 14.5
Note: Expression is at the basement membrane.
Specimen Label: 2C
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:2778222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564017
Age: embryonic day 14.5
Note: Expression in the epithelial basement membrane of renal tubules.
Specimen Label: 2C
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564017
Age: embryonic day 14.5
Note: Expression is in the epithelial basement membrane of the skin.
Specimen Label: 1B
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564017
Age: embryonic day 14.5
Note: Expression is in the epithelial basement membrane of the developing airways and visceral pleura in the lung.
Specimen Label: 1G
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564017
Age: embryonic day 14.5
Note: Expression is in the epithelial basement membrane of the kidney.
Specimen Label: 1L
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3803122
Stage: TS22
Assay Id: MGI:7564017
Age: embryonic day 14.5
Note: Expression in the epithelial basement membrane of the skin in this mutant is absent.
Specimen Label: 2A
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3803122
Stage: TS22
Assay Id: MGI:7564017
Age: embryonic day 14.5
Note: Expression in the epithelial basement membrane of the lung in this mutant is absent.
Specimen Label: 2B
Detected: false
Specimen Num: 5
GXD Expression  
Probe: MGI:3707380
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564017
Age: embryonic day 14.5
Note: Expression in the epithelial basement membrane of renal tubules.
Specimen Label: 2C
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564022
Age: embryonic day 14.5
Note: Expression is in the epithelial basement membrane of the skin.
Specimen Label: 1D
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564022
Age: embryonic day 14.5
Note: Expression is in the epithelial basement membrane of the developing airways and visceral pleura in the lung.
Specimen Label: 1I
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564022
Age: embryonic day 14.5
Note: Expression is in the epithelial basement membrane of the kidney.
Specimen Label: 1N
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564022
Age: embryonic day 14.5
Note: Expression in the epithelial basement membrane of the skin in this mutant is the same as in wild-type.
Specimen Label: 2G
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564022
Age: embryonic day 14.5
Note: Expression in the epithelial basement membrane of the lung in this mutant is the same as in wild-type.
Specimen Label: 2H
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3707385
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564022
Age: embryonic day 14.5
Note: Expression in the epithelial basement membrane of the kidney in this mutant is the same as in wild-type.
Specimen Label: 2I
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:7468618
Assay Type: RNA in situ
Annotation Date: 2023-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3818518
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:7468631
Age: embryonic day 10.75
Image: 2D
Note: Gradient of expression in mesenchyme of maxillary process.
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6199518
Assay Type: Immunohistochemistry
Annotation Date: 2018-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6199614
Age: postnatal newborn
Note: Expressed in distinct regions, anchoring plaques, in the dermis close to the basement membrane. Stained patches often occurred where anchoring fibrils fuse. Collagen VII and Fras1 often occur at opposite sides of anchoring plaques.
Specimen Label: 3c
Detected: true
Specimen Num: 1
DO Term
Publication
First Author: Grüneberg H
Year: 1971
Journal: J Embryol Exp Morphol
Title: Exocrine glands and the Chievitz organ of some mouse mutants.
Volume: 25
Issue: 2
Pages: 247-61
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: endonuclease-mediated mutation, mutant stock
Strain
Attribute String: coisogenic
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele  
Name: Fras1 related extracellular matrix protein 2; Bench to Bassinet Program (B2B/CVDC), mutation 3270 Cecilia Lo
Allele Type: Chemically induced (ENU)
Strain
Attribute String: coisogenic, chemically induced mutation, mutant strain
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: inbred strain, spontaneous mutation
Strain
Attribute String: F1 hybrid, mutant stock
Strain
Attribute String: mutant stock
Strain
Attribute String: mutant stock, targeted mutation
Strain
Attribute String: chemically induced mutation, coisogenic, mutant strain
Strain
Attribute String: chemically induced mutation, coisogenic, mutant strain
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Frem1/Frem1<+>
Background: C57BL/6J-Frem1
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Frem1/Frem1
Background: involves: 129 * C57BL * C57BL/6 * DBA
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem1/Frem1
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem2/Frem2
Background: C57BL/6J-Frem2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem2/Frem2
Background: C57BL/6J-Frem2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem3/Frem3
Background: C57BL/6N-Frem3/BayMmucd
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem2/Frem2<+>
Background: involves: MY/HuLeJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Frem2/Frem2<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Frem1/Frem1<+>
Background: involves: 129 * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Frem1/Frem1<+>
Background: involves: 129
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Davisson MT
Year: 1976
Journal: J Hered
Title: Genes on chromosome 3 of the mouse.
Volume: 67
Issue: 3
Pages: 155-6
Publication
First Author: Eicher EM
Year: 1980
Journal: J Hered
Title: Assignment of LH XVI to chromosome 3 in the mouse.
Volume: 71
Issue: 5
Pages: 315-8
Strain
Attribute String: mutant strain, endonuclease-mediated mutation, coisogenic
Genotype
Symbol: Frem2/Frem2
Background: C57BL/6J-Frem2 Frem2
Zygosity: ht
Has Mutant Allele: true
Allele
Name: glutamate receptor interacting protein 1; targeted mutation 1, Ralf H Adams
Allele Type: Targeted
Attribute String: Null/knockout
Allele  
Name: Fraser extracellular matrix complex subunit 1; blood filled blisters
Allele Type: Chemically induced (ENU)
Allele
Name: Fraser extracellular matrix complex subunit 1; targeted mutation 1, George Chalepakis
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: Fraser extracellular matrix complex subunit 1; rounded foot
Allele Type: Chemically induced (ENU)
Attribute String: Null/knockout
Publication  
First Author: Fox S
Year: 1977
Journal: Mouse News Lett
Title: Er - Gpd-1 linkage.
Volume: 57
Pages: 21
Publication
First Author: Hentges KE
Year: 2006
Journal: Gene Expr Patterns
Title: Novel lethal mouse mutants produced in balancer chromosome screens.
Volume: 6
Issue: 6
Pages: 653-65
Publication      
First Author: The Mouse Genome Project at The Baylor College of Medicine
Year: 2004
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the Mouse Mutagenesis for Developmental Defects Program
Protein Domain
Type: Family
Description: FREM1 (FRAS1-related extracellular matrix protein 1) is an extracellular matrix protein that forms a ternary complex in the basement membrane with FRAS1 and FREM2 during epidermal development []. FREM1 also appears to act as a dermal mediator of basement membrane adhesion independently of the FRAS1 []. Mutations in the FREM1 gene cause two rare syndromes - bifid nose with or without anorectal and renal anomalies syndrome (BNAR; OMIM #608980) and Manitoba oculotrichoanal syndrome (MOTA; OMIM #248450) - whose phenotypic characteristics overlap those seen in individuals with Fraser syndrome [].
Allele  
Name: glutamate receptor interacting protein 1; eye blebs
Allele Type: Spontaneous