|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 292 out of 292 for Ehmt1

<< First    < Previous  |  Next >    Last >>
0.027s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication    
First Author: Zylicz JJ
Year: 2018
Journal: Elife
Title: G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst.
Volume: 7
Publication
First Author: Deguchi K
Year: 2013
Journal: Biol Reprod
Title: Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells.
Volume: 88
Issue: 2
Pages: 36
Publication
First Author: Dan J
Year: 2014
Journal: Dev Cell
Title: Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing.
Volume: 29
Issue: 1
Pages: 7-19
Publication
First Author: Yamaji M
Year: 2008
Journal: Nat Genet
Title: Critical function of Prdm14 for the establishment of the germ cell lineage in mice.
Volume: 40
Issue: 8
Pages: 1016-22
Publication
First Author: Hatazawa Y
Year: 2018
Journal: FASEB J
Title: Reduced Dnmt3a increases Gdf5 expression with suppressed satellite cell differentiation and impaired skeletal muscle regeneration.
Volume: 32
Issue: 3
Pages: 1452-1467
Publication
First Author: Trojer P
Year: 2009
Journal: J Biol Chem
Title: Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.
Volume: 284
Issue: 13
Pages: 8395-405
Publication
First Author: Lyons DB
Year: 2014
Journal: Cell Rep
Title: Heterochromatin-mediated gene silencing facilitates the diversification of olfactory neurons.
Volume: 9
Issue: 3
Pages: 884-92
Publication    
First Author: Zylicz JJ
Year: 2015
Journal: Elife
Title: Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development.
Volume: 4
Publication
First Author: Benlhabib H
Year: 2011
Journal: Mol Cell Biol
Title: Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia.
Volume: 31
Issue: 10
Pages: 1949-58
Publication
First Author: Ideno H
Year: 2013
Journal: Gene Expr Patterns
Title: Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development.
Volume: 13
Issue: 3-4
Pages: 84-90
Publication
First Author: Sridharan R
Year: 2013
Journal: Nat Cell Biol
Title: Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency.
Volume: 15
Issue: 7
Pages: 872-82
Publication
First Author: Kuroki S
Year: 2017
Journal: PLoS Genet
Title: Rescuing the aberrant sex development of H3K9 demethylase Jmjd1a-deficient mice by modulating H3K9 methylation balance.
Volume: 13
Issue: 9
Pages: e1007034
Publication
First Author: Inagawa M
Year: 2013
Journal: Mech Dev
Title: Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.
Volume: 130
Issue: 11-12
Pages: 519-31
Publication
First Author: Tachibana M
Year: 2007
Journal: EMBO J
Title: Functional dynamics of H3K9 methylation during meiotic prophase progression.
Volume: 26
Issue: 14
Pages: 3346-59
Publication
First Author: Pirouz M
Year: 2013
Journal: PLoS Genet
Title: A critical function of Mad2l2 in primordial germ cell development of mice.
Volume: 9
Issue: 8
Pages: e1003712
Publication
First Author: Holt JE
Year: 2014
Journal: Development
Title: The APC/C activator FZR1 is essential for meiotic prophase I in mice.
Volume: 141
Issue: 6
Pages: 1354-65
Publication
First Author: Matsuura T
Year: 2017
Journal: Sci Rep
Title: Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin.
Volume: 7
Issue: 1
Pages: 12462
Publication  
First Author: Bukova I
Year: 2021
Journal: Front Cell Dev Biol
Title: Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate.
Volume: 9
Pages: 620692
Publication
First Author: Wang J
Year: 2007
Journal: Nature
Title: Opposing LSD1 complexes function in developmental gene activation and repression programmes.
Volume: 446
Issue: 7138
Pages: 882-7
Publication  
First Author: Zhang F
Year: 2021
Journal: Front Cell Dev Biol
Title: Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.
Volume: 9
Pages: 642931
Publication
First Author: Allis CD
Year: 2007
Journal: Cell
Title: New nomenclature for chromatin-modifying enzymes.
Volume: 131
Issue: 4
Pages: 633-6
Publication      
First Author: Overbeek PA
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Overbeek Lentiviral Transgenic Lines
Publication
First Author: Prokopuk L
Year: 2022
Journal: Reproduction
Title: An essential role for Polycomb Repressive Complex 2 in the mouse ovary.
Volume: 163
Issue: 3
Pages: 167-182
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication    
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 4
Pages: 167-80
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
UniProt Feature
Begin: 2
Description: Histone-lysine N-methyltransferase EHMT1
Type: chain
End: 1296
UniProt Feature
Begin: 186
Description: N6-methyllysine; by EHMT1 and EHMT2
Type: modified residue
End: 186
Protein
Organism: Mus musculus/domesticus
Length: 1248  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1243  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 24  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: false
UniProt Feature
Begin: 370
Description: N6,N6-dimethyllysine; by EHMT1 and EHMT2; alternate
Type: modified residue
End: 370
Allele
Name: euchromatic histone methyltransferase 1; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: euchromatic histone methyltransferase 1; targeted mutation 1, Yoichi Shinkai
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: euchromatic histone methyltransferase 1; targeted mutation 1.1, Alexander Tarakhovsky
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Protein Domain
Type: Family
Description: Histone-lysine N-methyltransferase EHMT1, () mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin []. H3K9me is a specific tag for repression of epigenetic transcription, recruiting HP1 proteins to methylated histones. EHMT1 also methylates 'Lys-27' of histone H3 (H3K27me), but weakly []. EHMT1 also dimethylates other proteins, including 'Lys-373' of p53 []. EHMT1 forms a heterodimer with EHMT2 [], and is a component of the E2F6.com-1 complex in G0 phase []. EHMT1 contains eight ankyrin repeats which bind the monomethylated RELA subunit of NF-kappa-B, a SET domain which interacts with WIZ [], and a pre-SET domain that binds three zinc ions via cysteine residues [].
Genotype
Symbol: Ehmt1/Ehmt1 Tg(Camk2a-cre)2Gsc/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ehmt1/Ehmt1<+>
Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: ht
Has Mutant Allele: true
DO Term
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Protein
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 155  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 441  
Fragment?: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Publication
First Author: Yu Y
Year: 2012
Journal: Mol Cell
Title: Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA.
Volume: 46
Issue: 1
Pages: 7-17
Publication
First Author: Rathert P
Year: 2008
Journal: Nat Chem Biol
Title: Protein lysine methyltransferase G9a acts on non-histone targets.
Volume: 4
Issue: 6
Pages: 344-6
Protein Domain
Type: Family
Description: Histone-lysine N-methyltransferase EHMT2 () mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin []. H3K9me is a specific tag for repression of epigenetic transcription, recruiting HP1 proteins to methylated histones. EHMT2 also monomethylates 'Lys-56' of histone H3 (H3K56me1) during the G1 phase of the cell cycle [], and methylates 'Lys-27' of histone H3 (H3K27me) []. EHMT2 also dimethylates other proteins [], including 'Lys-373' of p53 []. EHMT2 forms a heterdimer with EHMT1 [], and is a component of the E2F6.com-1 complex in G0 phase []. EHMT2 contains seven ankyrin repeats which bind the monomethylated RELA subunit of NF-kappa-B, a SET domain which interacts with WIZ [], and a pre-SET domain that binds three zinc ions via cysteine residues [].
Protein
Organism: Mus musculus/domesticus
Length: 1263  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1229  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1229  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 615  
Fragment?: true
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112