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Search results 601 to 650 out of 650 for Tet2

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Type

Details

Score

HT Experiment

GSE172127 | Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture [scRNA-seq]


Experiment Type:	RNA-Seq
Study Type:	Baseline
Source:	GEO

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Publication

23690950 | J:203146

First Author:	Liu N
Year:	2013
Journal:	PLoS One
Title:	Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules.
Volume:	8
Issue:	5
Pages:	e62755

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Publication

33432228 | J:302194

First Author:	Rivas MA
Year:	2021
Journal:	Nat Immunol
Title:	Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.
Volume:	22
Issue:	2
Pages:	240-253

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Publication

24336202 | J:207220

First Author:	Di Stefano B
Year:	2014
Journal:	Nature
Title:	C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells.
Volume:	506
Issue:	7487
Pages:	235-9

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Publication

28053194 | J:240427

First Author:	Liu J
Year:	2017
Journal:	Blood
Title:	miR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism.
Volume:	129
Issue:	11
Pages:	1491-1502

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Publication

28596252 | J:252696

First Author:	Cull AH
Year:	2017
Journal:	J Leukoc Biol
Title:	Success in bone marrow failure? Novel therapeutic directions based on the immune environment of myelodysplastic syndromes.
Volume:	102
Issue:	2
Pages:	209-219

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Publication

36909232 | J:334978

First Author:	Zhang M
Year:	2023
Journal:	Front Physiol
Title:	Delayed denervation-induced muscle atrophy in Opg knockout mice.
Volume:	14

Pages:	1127474

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Publication

22895193 | J:187151

First Author:	Seshagiri S
Year:	2012
Journal:	Nature
Title:	Recurrent R-spondin fusions in colon cancer.
Volume:	488
Issue:	7413
Pages:	660-4

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Publication

23558522 | J:199020

First Author:	Itzykson R
Year:	2013
Journal:	Leukemia
Title:	An evolutionary perspective on chronic myelomonocytic leukemia.
Volume:	27
Issue:	7
Pages:	1441-50

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Publication

24220273 | J:206977

First Author:	Solary E
Year:	2014
Journal:	Leukemia
Title:	The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases.
Volume:	28
Issue:	3
Pages:	485-96

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Publication

25423485 | J:225280

First Author:	Shpyleva S
Year:	2014
Journal:	PLoS One
Title:	Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum.
Volume:	9
Issue:	11
Pages:	e113712

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Publication

26601783 | J:231190

First Author:	Kiladjian JJ
Year:	2016
Journal:	Leukemia
Title:	Interferon-alpha for the therapy of myeloproliferative neoplasms: targeting the malignant clone.
Volume:	30
Issue:	4
Pages:	776-81

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Publication

28449087 | J:247059

First Author:	Zhang P
Year:	2017
Journal:	Nucleic Acids Res
Title:	Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner.
Volume:	45
Issue:	12
Pages:	7118-7136

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Publication

28855337 | J:253636

First Author:	Yosefzon Y
Year:	2017
Journal:	Proc Natl Acad Sci U S A
Title:	An epigenetic switch repressing Tet1 in gonadotropes activates the reproductive axis.
Volume:	114
Issue:	38
Pages:	10131-10136

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Publication

29769264 | J:266032

First Author:	Ng SY
Year:	2018
Journal:	Blood
Title:	RhoA G17V is sufficient to induce autoimmunity and promotes T-cell lymphomagenesis in mice.
Volume:	132
Issue:	9
Pages:	935-947

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Publication

32938585 | J:299188

First Author:	Li S
Year:	2020
Journal:	Cancer Discov
Title:	Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML.
Volume:	10
Issue:	12
Pages:	1934-1949

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Publication

32961550 | J:303755

First Author:	Miller PG
Year:	2020
Journal:	Blood
Title:	Contribution of clonal hematopoiesis to adult-onset hemophagocytic lymphohistiocytosis.
Volume:	136
Issue:	26
Pages:	3051-3055

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Publication

34622806 | J:312389

First Author:	Man N
Year:	2021
Journal:	JCI Insight
Title:	p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia.
Volume:	6
Issue:	19

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Publication

34937926 | J:320564

First Author:	Shukla V
Year:	2022
Journal:	Nat Immunol
Title:	TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures.
Volume:	23
Issue:	1
Pages:	99-108

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Publication

34183665 | J:356124

First Author:	Lu Y
Year:	2021
Journal:	Cell Discov
Title:	Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture.
Volume:	7
Issue:	1
Pages:	47

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Publication

39131272 | J:361559

First Author:	Gioulbasani M
Year:	2024
Journal:	bioRxiv
Title:	TET proteins regulate Drosha expression and impact microRNAs in iNKT cells.

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Publication

16606617 | J:114350

First Author:	Cho YS
Year:	2006
Journal:	J Biol Chem
Title:	Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor.
Volume:	281
Issue:	26
Pages:	17588-98

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Protein

Q3UQU6

Organism:	Mus musculus/domesticus
Length:	173
Fragment?:	true

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Protein

G3UXC9

Organism:	Mus musculus/domesticus
Length:	104
Fragment?:	true

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Protein Domain

IPR007759 | Asxl_HARE-HTH

Type:

Domain

Description:

This domain, known as the HARE-HTH domain, adopts the winged helix-turn-helix fold and is predicted to bind DNA. It can be found at the N terminus of the ASXL protein. It can also be found in several other eukaryotic chromatin proteins (such as HB1 in plants), diverse restriction endonucleases and DNA glycosylases, the RNA polymerase delta subunit of Gram-positive bacteria and certain bacterial proteins that combine features of the RNA polymerase alpha-subunit and sigma factors []. The genetic interaction of the HARE-HTH containing ASXL with the methyl cytosine hydroxylating Tet2 protein is suggestive of a role for the domain in discriminating sequences with DNA modifications such as hmC []. Bacterial versions include fusions to diverse restriction endonucleases, and a DNA glycosylase where it may play a similar role in detecting modified DNA. Certain bacterial version of the HARE-HTH domain show fusions to the helix-hairpin-helix domain of the RNA polymerase alpha subunit and the HTH domains found in regions 3 and 4 of the sigma factors []. These versions are predicted to function as a novel inhibitor of the binding of RNA polymerase to transcription start sites, similar to the Bacillus delta protein [, ].This domain consists of four α-helices (helices I-II-III-IV) and an antiparallel β-sheet composed of three short β-strands at the top of a "twisted tripod"formed by helices II, III, and IV [].The Asx-like (Asxl) proteins includes Asxl1-3. They are putative Polycomb group (PcG) proteins, which act by forming multiprotein complexes that are required to maintain the transcriptionally repressive state of homeotic genes throughout development. Asxl1 is involved in transcriptional regulation mediated by ligand-bound retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG) [].The delta protein is a dispensable subunit of Bacillus subtilis RNA polymerase (RNAP) that has major effects on the biochemical properties of the purified enzyme. In the presence of delta, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increasedefficiency of RNA synthesis because of enhanced recycling []. The delta protein, contains two distinct regions, an N-terminal domain and a glutamate and aspartate residue-rich C-terminal region []. It participates in both the initiation and recycling phases of transcription.

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Publication

34621263 | J:312385

First Author:	Rivas MA
Year:	2021
Journal:	Front Immunol
Title:	Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes.
Volume:	12

Pages:	688493

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Publication

38048324 | J:360014

First Author:	Feng J
Year:	2023
Journal:	PLoS Pathog
Title:	NSUN2-mediated m5C modification of HBV RNA positively regulates HBV replication.
Volume:	19
Issue:	12
Pages:	e1011808

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Publication

29615405 | J:264226

First Author:	Inaba T
Year:	2018
Journal:	Blood
Title:	The enigma of monosomy 7.
Volume:	131
Issue:	26
Pages:	2891-2898

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Publication

33705482 | J:304554

First Author:	Ono R
Year:	2021
Journal:	PLoS One
Title:	Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models.
Volume:	16
Issue:	3
Pages:	e0248425

•

Publication

10336502 | -

First Author:	López de Saro FJ
Year:	1999
Journal:	J Biol Chem
Title:	Expression, abundance, and RNA polymerase binding properties of the delta factor of Bacillus subtilis.
Volume:	274
Issue:	22
Pages:	15953-8

•

Publication

7545758 | -

First Author:	López de Saro FJ
Year:	1995
Journal:	J Mol Biol
Title:	Structural analysis of the Bacillus subtilis delta factor: a protein polyanion which displaces RNA from RNA polymerase.
Volume:	252
Issue:	2
Pages:	189-202

•

Publication

20310067 | -

First Author:	Motácková V
Year:	2010
Journal:	Proteins
Title:	Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase and its classification based on structural homologs.
Volume:	78
Issue:	7
Pages:	1807-10

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Publication

31649729 | J:311748

First Author:	Malloy MA
Year:	2019
Journal:	Front Genet
Title:	Perinatal Bisphenol A Exposure and Reprogramming of Imprinted Gene Expression in the Adult Mouse Brain.
Volume:	10

Pages:	951

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Publication

35502657 | J:334535

First Author:	Chakraborty R
Year:	2022
Journal:	Circulation
Title:	Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.
Volume:	145
Issue:	23
Pages:	1720-1737

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Protein

P59598

Organism:	Mus musculus/domesticus
Length:	1514
Fragment?:	false

•

Protein

Q8BZ32

Organism:	Mus musculus/domesticus
Length:	1370
Fragment?:	false

•

Protein

Q8C4A5

Organism:	Mus musculus/domesticus
Length:	2259
Fragment?:	false

•

Protein

Q24JP2

Organism:	Mus musculus/domesticus
Length:	1514
Fragment?:	false

•

Protein

B2RUG8

Organism:	Mus musculus/domesticus
Length:	1418
Fragment?:	false

•

Protein

F6WV21

Organism:	Mus musculus/domesticus
Length:	1370
Fragment?:	false

•

Protein

D3Z112

Organism:	Mus musculus/domesticus
Length:	597
Fragment?:	false

•

Protein

A0A2I3BQW0

Organism:	Mus musculus/domesticus
Length:	1513
Fragment?:	false

•

Protein

D6REV1

Organism:	Mus musculus/domesticus
Length:	1370
Fragment?:	false

•

Protein

A0A668KLS4

Organism:	Mus musculus/domesticus
Length:	2260
Fragment?:	false

•

Protein

Q8BJR0

Organism:	Mus musculus/domesticus
Length:	495
Fragment?:	true

•

Protein

D6RI62

Organism:	Mus musculus/domesticus
Length:	403
Fragment?:	true

•

Publication

22186017 | -

First Author:	Aravind L
Year:	2012
Journal:	Cell Cycle
Title:	The HARE-HTH and associated domains: novel modules in the coordination of epigenetic DNA and protein modifications.
Volume:	11
Issue:	1
Pages:	119-31

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Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

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Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

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Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Search results 601 to 650 out of 650 for Tet2

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