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Search results 801 to 879 out of 879 for Sox17

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Type Details Score
GXD Expression
Probe: MGI:7543618
Assay Type: RNA in situ
Annotation Date: 2023-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1725616
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:7543630
Age: embryonic day 9.75
Image: 4H
Note: Expressed not only in the ventral pancreatic bud, but also in the region where Sox17 was intrinsically expressed (presumptive gall bladder region).
Specimen Label: 4H
Detected: true
Specimen Num: 12
GXD Expression
Probe: MGI:7541030
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160517
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541116
Age: embryonic day 5.0
Image: S3c -/-
Note: Positive cells did not exhibit epithelial structure but they appeared as a clump (accumulated Sox17 too), and exhibited defects in apical-basolateral polarity.
Specimen Label: S3c -/-
Detected: true
Specimen Num: 24
GXD Expression
Probe: MGI:7541030
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160517
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541116
Age: embryonic day 5.5
Image: S3d -/-
Note: Positive cells did not exhibit epithelial structure but they appeared as a clump (accumulated Sox17 too), and exhibited defects in apical-basolateral polarity.
Specimen Label: S3d -/-
Detected: true
Specimen Num: 26
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Li W
Year: 2019
Journal: Cell Commun Signal
Title: TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination.
Volume: 17
Issue: 1
Pages: 162
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Zorn AM
Year: 1999
Journal: Mol Cell
Title: Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin.
Volume: 4
Issue: 4
Pages: 487-98
Protein Domain
Type: Domain
Description: This is the central region of eukaryotic SOX17 and 18 transcription factor proteins []. It lies just downstream of the HMG-box domain, and is followed by a C-terminal domain.
Allele
Name: SRY (sex determining region Y)-box 17; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: regulatory region 270; endonuclease-mediated mutation 1, Mark A Magnuson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
Allele
Name: SRY (sex determining region Y)-box 17; targeted mutation 1, Sean J Morrison
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Strain
Attribute String: coisogenic, targeted mutation, mutant strain
Allele
Name: SRY (sex determining region Y)-box 17; targeted mutation 2, Sean J Morrison
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
HT Experiment
Series Id: GSE33353
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
Strain
Attribute String: congenic, mutant strain, targeted mutation
Allele
Name: SRY (sex determining region Y)-box 17; targeted mutation 2.1, Heiko Lickert
Allele Type: Targeted
Attribute String: Recombinase
Allele
Name: SRY (sex determining region Y)-box 17; targeted mutation 1, Heiko Lickert
Allele Type: Targeted
Attribute String: Recombinase
Genotype
Symbol: Sox17/Sox17
Background: BKa.129-Sox17
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Rr270/Rr270
Background: involves: CD-1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Allele
Name: SRY (sex determining region Y)-box 17; targeted mutation 4.1, Heiko Lickert
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Sox17/Sox17 Tg(Cdh5-cre/ERT2)1Rha/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17<+> Tbx1/Tbx1
Background: involves: 129S6/SvEvTac * 129/Sv * C57BL/6J * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17<+>
Background: involves: 129S2/SvPas * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fgf8/Fgf8 Sox17/Sox17<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17<+> Tg(CAG-cat,-EGFP)1Rbns/?
Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mesp1/Mesp1<+> Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17 Tg(Nfat1c-cre)1Bz/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Perl AK
Year: 2005
Journal: Genesis
Title: Normal lung development and function after Sox9 inactivation in the respiratory epithelium.
Volume: 41
Issue: 1
Pages: 23-32
Publication
First Author: Cheng CW
Year: 2017
Journal: Cell
Title: Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes.
Volume: 168
Issue: 5
Pages: 775-788.e12
Publication
First Author: Frankenberg S
Year: 2011
Journal: Dev Cell
Title: Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling.
Volume: 21
Issue: 6
Pages: 1005-13
Publication
First Author: Zhang K
Year: 2013
Journal: Dev Biol
Title: Depletion of Suds3 reveals an essential role in early lineage specification.
Volume: 373
Issue: 2
Pages: 359-72
Publication  
First Author: Liu Y
Year: 2022
Journal: Gene Expr Patterns
Title: Expression patterns and biological function of BCL2L10 during mouse preimplantation development.
Volume: 46
Pages: 119285
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Sox17/Sox17 Tg(Mx1-cre)1Cgn/?
Background: involves: 129/Sv * C3H * C57BL/6 * C57BL/Ka * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17 Tg(Foxa3-cre)1Khk/?
Background: involves: 129 * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nipbl/Nipbl<+> Sox17/Sox17<+>
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nipbl/Nipbl<+> Sox17/Sox17<+>
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox17/Sox17<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fgf3/Fgf3<+> Fgf8/Fgf8<+> Sox17/Sox17<+>
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fgfr1/Fgfr1 Fgfr2/Fgfr2 Sox17/Sox17<+>
Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Horowitz E
Year: 2005
Journal: Mol Hum Reprod
Title: Patterns of expression of sperm flagellar genes: early expression of genes encoding axonemal proteins during the spermatogenic cycle and shared features of promoters of genes encoding central apparatus proteins.
Volume: 11
Issue: 4
Pages: 307-17
Publication
First Author: Hara K
Year: 2009
Journal: Dev Biol
Title: Evidence for crucial role of hindgut expansion in directing proper migration of primordial germ cells in mouse early embryogenesis.
Volume: 330
Issue: 2
Pages: 427-39
Publication
First Author: Pierce SE
Year: 2021
Journal: Nat Cell Biol
Title: LKB1 inactivation modulates chromatin accessibility to drive metastatic progression.
Volume: 23
Issue: 8
Pages: 915-924
Publication
First Author: Lin SC
Year: 2010
Journal: Development
Title: Klf5 regulates lineage formation in the pre-implantation mouse embryo.
Volume: 137
Issue: 23
Pages: 3953-63
Publication
First Author: Lee JW
Year: 2023
Journal: Exp Mol Med
Title: SOX17-mediated LPAR4 expression plays a pivotal role in cardiac development and regeneration after myocardial infarction.
Volume: 55
Issue: 7
Pages: 1424-1436
Publication
First Author: Yang D
Year: 2014
Journal: Development
Title: miR-335 promotes mesendodermal lineage segregation and shapes a transcription factor gradient in the endoderm.
Volume: 141
Issue: 3
Pages: 514-25
Publication
First Author: Taylor-Weiner H
Year: 2015
Journal: J Cell Sci
Title: Traction forces mediated by integrin signaling are necessary for definitive endoderm specification.
Volume: 128
Issue: 10
Pages: 1961-8
Publication
First Author: Chatagnon A
Year: 2015
Journal: Nucleic Acids Res
Title: RAR/RXR binding dynamics distinguish pluripotency from differentiation associated cis-regulatory elements.
Volume: 43
Issue: 10
Pages: 4833-54
Publication  
First Author: Vargel Ö
Year: 2016
Journal: Sci Rep
Title: Activation of the TGFβ pathway impairs endothelial to haematopoietic transition.
Volume: 6
Pages: 21518
Publication
First Author: Shi Y
Year: 2021
Journal: Biol Reprod
Title: Functional roles of the chromatin remodeler SMARCA5 in mouse and bovine preimplantation embryos†.
Volume: 105
Issue: 2
Pages: 359-370
Genotype
Symbol: Sox17/Sox17 Tg(Tek-cre)12Flv/?
Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * C57BL/Ka
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fgf3/Fgf3 Fgf8/Fgf8<+> Sox17/Sox17<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fgf3/Fgf3<+> Fgf8/Fgf8 Sox17/Sox17<+>
Background: involves: 129P2/OlaHsd * 129S * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fgf3/Fgf3 Fgf8/Fgf8 Sox17/Sox17<+>
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17<+>
Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Sox17/Sox17
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Setdb1/Setdb1<+> Sox17/Sox17<+> Tg(CAG-cat,-EGFP)1Rbns/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Setdb1/Setdb1 Sox17/Sox17<+> Tg(CAG-cat,-EGFP)1Rbns/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
Publication
First Author: Chew LJ
Year: 2011
Journal: J Neurosci
Title: SRY-box containing gene 17 regulates the Wnt/β-catenin signaling pathway in oligodendrocyte progenitor cells.
Volume: 31
Issue: 39
Pages: 13921-35
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7