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Search results 201 to 281 out of 281 for Ago1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4425345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824504
Age: embryonic day 14.5
Image: euxassay_012863_21
Specimen Label: euxassay_012863_21
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
Probe: MGI:4425345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824504
Age: embryonic day 14.5
Image: euxassay_012863_08
Note: facial motor nucleus
Specimen Label: euxassay_012863_08
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:4425345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824504
Age: embryonic day 14.5
Image: euxassay_012863_09
Note: facial motor nucleus
Specimen Label: euxassay_012863_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:4425345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824504
Age: embryonic day 14.5
Image: euxassay_012863_15
Note: facial motor nucleus
Specimen Label: euxassay_012863_15
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
Probe: MGI:4425345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824504
Age: embryonic day 14.5
Image: euxassay_012863_16
Note: facial motor nucleus
Specimen Label: euxassay_012863_16
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
   
Probe: MGI:3587199
Assay Type: RNA in situ
Annotation Date: 2005-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:3587207
Age: embryonic day 11.5
Specimen Label: 1 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4425345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824504
Age: embryonic day 14.5
Image: euxassay_012863_09
Specimen Label: euxassay_012863_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:4425345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824504
Age: embryonic day 14.5
Image: euxassay_012863_10
Specimen Label: euxassay_012863_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:4425345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824504
Age: embryonic day 14.5
Image: euxassay_012863_14
Specimen Label: euxassay_012863_14
Detected: true
Specimen Num: 14
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Publication
17626790 | J:165967
First Author: O'Carroll D
Year: 2007
Journal: Genes Dev
Title: A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway.
Volume: 21
Issue: 16
Pages: 1999-2004
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Publication
22318144 | J:186108
First Author: Van Stry M
Year: 2012
Journal: J Virol
Title: Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection.
Volume: 86
Issue: 8
Pages: 4151-7
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Publication
30201950 | J:268670
First Author: Zhang C
Year: 2018
Journal: Nat Commun
Title: Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology.
Volume: 9
Issue: 1
Pages: 3658
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Publication
32049003 | J:288072
First Author: Adiliaghdam F
Year: 2020
Journal: Cell Rep
Title: A Requirement for Argonaute 4 in Mammalian Antiviral Defense.
Volume: 30
Issue: 6
Pages: 1690-1701.e4
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Publication
19536157 | J:150716
First Author: Chi SW
Year: 2009
Journal: Nature
Title: Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
Volume: 460
Issue: 7254
Pages: 479-86
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Publication
12526743 | J:92289
First Author: Doi N
Year: 2003
Journal: Curr Biol
Title: Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.
Volume: 13
Issue: 1
Pages: 41-6
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Publication
12414724 | J:79881
First Author: Carmell MA
Year: 2002
Journal: Genes Dev
Title: The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis.
Volume: 16
Issue: 21
Pages: 2733-42
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Publication
26850657 | J:258947
First Author: Pua HH
Year: 2016
Journal: Immunity
Title: MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production.
Volume: 44
Issue: 4
Pages: 821-32
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Publication
20424607 | J:161968
First Author: Cheloufi S
Year: 2010
Journal: Nature
Title: A dicer-independent miRNA biogenesis pathway that requires Ago catalysis.
Volume: 465
Issue: 7298
Pages: 584-9
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Publication
19345100 | J:148941
First Author: Wang J
Year: 2009
Journal: Curr Biol
Title: Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis.
Volume: 19
Issue: 8
Pages: 640-4
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Publication
20014101 | J:156954
First Author: Hu J
Year: 2010
Journal: Dev Dyn
Title: Mouse ZAR1-like (XM_359149) colocalizes with mRNA processing components and its dominant-negative mutant caused two-cell-stage embryonic arrest.
Volume: 239
Issue: 2
Pages: 407-24
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Publication
29021386 | J:286965
First Author: Hajarnis S
Year: 2018
Journal: J Am Soc Nephrol
Title: Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.
Volume: 29
Issue: 2
Pages: 518-531
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Publication
19269368 | J:145909
First Author: Schwamborn JC
Year: 2009
Journal: Cell
Title: The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors.
Volume: 136
Issue: 5
Pages: 913-25
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Publication
34907157 | J:317196
First Author: Zhang Y
Year: 2021
Journal: Cell Death Dis
Title: Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development.
Volume: 12
Issue: 12
Pages: 1161
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Publication
19898466 | J:158290
First Author: Rybak A
Year: 2009
Journal: Nat Cell Biol
Title: The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2.
Volume: 11
Issue: 12
Pages: 1411-20
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Publication
20102707 | J:160269
First Author: Michon F
Year: 2010
Journal: Dev Biol
Title: Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs.
Volume: 340
Issue: 2
Pages: 355-68
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Publication
22508726 | J:183920
First Author: Chen J
Year: 2012
Journal: Genes Dev
Title: The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling.
Volume: 26
Issue: 8
Pages: 803-15
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Ago1<tm1Smoc> | MGI:7786803
Name: argonaute RISC catalytic subunit 1; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:7788630 | C57BL/6JSmoc-Ago1<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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HT Experiment
E-GEOD-32935 | The Expression of MicroRNA and microRNA Clusters in the Aging Heart
Series Id: GSE32935
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
19767612 | J:173016
First Author: Vickers TA
Year: 2009
Journal: Nucleic Acids Res
Title: Off-target and a portion of target-specific siRNA mediated mRNA degradation is Ago2 'Slicer' independent and can be mediated by Ago1.
Volume: 37
Issue: 20
Pages: 6927-41
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Publication
22539551 | -
First Author: Schirle NT
Year: 2012
Journal: Science
Title: The crystal structure of human Argonaute2.
Volume: 336
Issue: 6084
Pages: 1037-40
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Publication
20675357 | -
First Author: Chu Y
Year: 2010
Journal: Nucleic Acids Res
Title: Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter.
Volume: 38
Issue: 21
Pages: 7736-48
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Publication
17932509 | -
First Author: Höck J
Year: 2007
Journal: EMBO Rep
Title: Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.
Volume: 8
Issue: 11
Pages: 1052-60
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Publication
28114302 | -
First Author: Golden RJ
Year: 2017
Journal: Nature
Title: An Argonaute phosphorylation cycle promotes microRNA-mediated silencing.
Volume: 542
Issue: 7640
Pages: 197-202
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Protein Domain
IPR028602 | AGO2
Type: Family
Description: Argonaute proteins are involved in RNA interference (RNAi) and microRNA (miRNA) pathways. They can be classified into three paralogous groups: Argonaute-like proteins, which are similar to Arabidopsis thaliana AGO1; Piwi-like proteins, which are closely related to D. melanogaster PIWI (P-element induced wimpy testis); and the Caenorhabditis elegans-specific group 3 Argonautes []. Protein argonaute-2 (AGO2) belongs to the first group (Argonaute-like proteins). It is a component of the RNA-induced silencing complex (RISC) that functions in RNA-mediated gene silencing (RNAi) [, ]. AGO2 is the catalytic engine that drives mRNA cleavage in the RNAi pathway []. AGO2 suffers a phosphorylation cycle that is triggered by target engagement and negatively regulates target association, which is essential to maintain the global efficiency of miRNA-mediated silencing []. It is also the primary AGO variant involved in modulating expression of progesterone receptor by antigene RNAs []. AGO1 and AGO2 reside in three complexes with distinct Dicer and RNA-induced silencing complex activities []. The structure of AGO2 has been solved [].
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Publication
19174539 | J:144999
First Author: Su H
Year: 2009
Journal: Genes Dev
Title: Essential and overlapping functions for mammalian Argonautes in microRNA silencing.
Volume: 23
Issue: 3
Pages: 304-17
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Publication
10534406 | J:58290
First Author: Koesters R
Year: 1999
Journal: Genomics
Title: Human eukaryotic initiation factor EIF2C1 gene: cDNA sequence, genomic organization, localization to chromosomal bands 1p34-p35, and expression.
Volume: 61
Issue: 2
Pages: 210-8
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Publication
22529925 | J:356974
First Author: Zhang X
Year: 2012
Journal: PLoS One
Title: The expression of microRNA and microRNA clusters in the aging heart.
Volume: 7
Issue: 4
Pages: e34688
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Publication
18073770 | -
First Author: Hutvagner G
Year: 2008
Journal: Nat Rev Mol Cell Biol
Title: Argonaute proteins: key players in RNA silencing.
Volume: 9
Issue: 1
Pages: 22-32
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Protein
Q8CJG0
Organism: Mus musculus/domesticus
Length: 860  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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