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Search results 701 to 800 out of 1154 for Ins2

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Type Details Score
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
23894189 | J:208935
First Author: Ghazarian L
Year: 2013
Journal: Diabetes
Title: Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT-cell stimulation: role of suppressive macrophages.
Volume: 62
Issue: 11
Pages: 3785-96
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Publication
24127484 | J:206540
First Author: Mohan JF
Year: 2013
Journal: J Exp Med
Title: Pathogenic CD4⁺ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes.
Volume: 210
Issue: 11
Pages: 2403-14
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Publication
24114270 | J:201964
First Author: Fu X
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation.
Volume: 110
Issue: 44
Pages: 17892-7
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Publication
15467835 | J:93420
First Author: Georgia S
Year: 2004
Journal: J Clin Invest
Title: Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.
Volume: 114
Issue: 7
Pages: 963-8
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Publication
27495224 | J:252010
First Author: Thayer TC
Year: 2016
Journal: Diabetes
Title: Peripheral Proinsulin Expression Controls Low-Avidity Proinsulin-Reactive CD8 T Cells in Type 1 Diabetes.
Volume: 65
Issue: 11
Pages: 3429-3439
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Publication
30796028 | J:273801
First Author: Pearson JA
Year: 2019
Journal: Diabetes
Title: Altered Gut Microbiota Activate and Expand Insulin B15-23-Reactive CD8+ T Cells.
Volume: 68
Issue: 5
Pages: 1002-1013
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Publication
26953160 | J:252132
First Author: Pearson JA
Year: 2016
Journal: Diabetes
Title: Proinsulin Expression Shapes the TCR Repertoire but Fails to Control the Development of Low-Avidity Insulin-Reactive CD8+ T Cells.
Volume: 65
Issue: 6
Pages: 1679-89
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Publication
8631275 | J:32017
First Author: Offield MF
Year: 1996
Journal: Development
Title: PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum.
Volume: 122
Issue: 3
Pages: 983-95
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Publication
16962573 | J:119565
First Author: Boyer DF
Year: 2006
Journal: Dev Biol
Title: Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression.
Volume: 298
Issue: 2
Pages: 616-31
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Publication
11577200 | J:72169
First Author: Lammert E
Year: 2001
Journal: Science
Title: Induction of pancreatic differentiation by signals from blood vessels.
Volume: 294
Issue: 5542
Pages: 564-7
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Publication
27292642 | J:238301
First Author: Henley KD
Year: 2016
Journal: Cell Rep
Title: Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.
Volume: 15
Issue: 12
Pages: 2637-2650
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Publication
35435956 | J:341884
 
First Author: Ramzy A
Year: 2022
Journal: Endocrinology
Title: Insulin Null β-cells Have a Prohormone Processing Defect That Is Not Reversed by AAV Rescue of Proinsulin Expression.
Volume: 163
Issue: 6
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Publication
32715748 | J:296858
First Author: Botezelli JD
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Adipose depot-specific upregulation of Ucp1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice.
Volume: 319
Issue: 3
Pages: E529-E539
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27656411 | J:270437
First Author: Neumann UH
Year: 2016
Journal: Mol Metab
Title: Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival.
Volume: 5
Issue: 8
Pages: 731-736
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Publication
22065673 | J:178627
First Author: Mohan JF
Year: 2011
Journal: J Exp Med
Title: Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion.
Volume: 208
Issue: 12
Pages: 2375-83
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Publication
31836691 | J:285328
First Author: Bettini M
Year: 2020
Journal: Diabetes
Title: A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells.
Volume: 69
Issue: 3
Pages: 392-400
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Publication
29029025 | J:256398
First Author: Ramzy A
Year: 2018
Journal: Endocrinology
Title: Insulin-Deficient Mouse β-Cells Do Not Fully Maturebut Can Be Remedied Through Insulin Replacementby Islet Transplantation.
Volume: 159
Issue: 1
Pages: 83-102
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27145011 | J:239731
First Author: Dionne DA
Year: 2016
Journal: Endocrinology
Title: Caloric Restriction Paradoxically Increases Adiposity in Mice With Genetically Reduced Insulin.
Volume: 157
Issue: 7
Pages: 2724-34
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16289958 | J:106579
First Author: Nakayama M
Year: 2005
Journal: J Autoimmun
Title: Thymic expression of mutated B16:A preproinsulin messenger RNA does not reverse acceleration of NOD diabetes associated with insulin 2 (thymic expressed insulin) knockout.
Volume: 25
Issue: 3
Pages: 193-8
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Publication
15889095 | J:98583
First Author: Nakayama M
Year: 2005
Journal: Nature
Title: Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.
Volume: 435
Issue: 7039
Pages: 220-3
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Publication
17459508 | J:136741
 
First Author: Moriyama H
Year: 2007
Journal: Diabetes Res Clin Pract
Title: Insulin as a T cell antigen in type 1 diabetes supported by the evidence from the insulin knockout NOD mice.
Volume: 77 Suppl 1
Pages: S155-60
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26696124 | J:233842
First Author: Neumann UH
Year: 2016
Journal: Endocrinology
Title: Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy.
Volume: 157
Issue: 3
Pages: 1007-12
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16039605 | J:99957
First Author: Schechter R
Year: 2005
Journal: Biochem Biophys Res Commun
Title: The effect of insulin deficiency on tau and neurofilament in the insulin knockout mouse.
Volume: 334
Issue: 4
Pages: 979-86
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Publication
32644973 | J:298233
 
First Author: Lee J
Year: 2020
Journal: JCI Insight
Title: Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production.
Volume: 5
Issue: 16
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12925730 | J:85309
First Author: Moriyama H
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse.
Volume: 100
Issue: 18
Pages: 10376-81
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Publication
24943217 | J:312759
First Author: Bettini M
Year: 2014
Journal: J Immunol
Title: TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
Volume: 193
Issue: 2
Pages: 571-9
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Publication
23722904 | J:201431
First Author: Wright J
Year: 2013
Journal: J Clin Invest
Title: Dominant protein interactions that influence the pathogenesis of conformational diseases.
Volume: 123
Issue: 7
Pages: 3124-34
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14688305 | J:87572
First Author: Faideau B
Year: 2004
Journal: J Immunol
Title: Expression of preproinsulin-2 gene shapes the immune response to preproinsulin in normal mice.
Volume: 172
Issue: 1
Pages: 25-33
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Publication
12475795 | J:107164
 
First Author: Dubois-Lafforgue D
Year: 2002
Journal: Diabetes
Title: Proinsulin 2 knockout NOD mice: a model for genetic variation of insulin gene expression in type 1 diabetes.
Volume: 51 Suppl 3
Pages: S489-93
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Publication
12639991 | J:82522
First Author: Thébault-Baumont K
Year: 2003
Journal: J Clin Invest
Title: Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice.
Volume: 111
Issue: 6
Pages: 851-7
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Publication
21817126 | J:180723
First Author: Alejandro EU
Year: 2011
Journal: FASEB J
Title: Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription.
Volume: 25
Issue: 11
Pages: 3884-95
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Publication
26631740 | J:246400
First Author: Paul L
Year: 2016
Journal: Diabetes
Title: Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells.
Volume: 65
Issue: 3
Pages: 687-98
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15930104 | J:98803
First Author: Collombat P
Year: 2005
Journal: Development
Title: The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas.
Volume: 132
Issue: 13
Pages: 2969-80
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16423820 | J:104222
First Author: Fazio EN
Year: 2005
Journal: J Endocrinol
Title: Altered Glut-2 accumulation and beta-cell function in mice lacking the exocrine-specific transcription factor, Mist1.
Volume: 187
Issue: 3
Pages: 407-18
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16306355 | J:104307
First Author: Wilson ME
Year: 2005
Journal: Diabetes
Title: The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas.
Volume: 54
Issue: 12
Pages: 3402-9
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26576643 | J:321242
First Author: Nivlet L
Year: 2016
Journal: J Mol Endocrinol
Title: Expression and functional studies of the GDNF family receptor alpha 3 in the pancreas.
Volume: 56
Issue: 2
Pages: 77-90
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17141632 | J:144661
First Author: Zhang W
Year: 2006
Journal: Cell Metab
Title: PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.
Volume: 4
Issue: 6
Pages: 491-7
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31519700 | J:282308
First Author: Romer AI
Year: 2019
Journal: Diabetes
Title: Murine Perinatal β-Cell Proliferation and the Differentiation of Human Stem Cell-Derived Insulin-Expressing Cells Require NEUROD1.
Volume: 68
Issue: 12
Pages: 2259-2271
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22675211 | J:185601
First Author: Shih HP
Year: 2012
Journal: Development
Title: A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.
Volume: 139
Issue: 14
Pages: 2488-99
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30620636 | J:274021
First Author: Bethea M
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: The islet-expressed Lhx1 transcription factor interacts with Islet-1 and contributes to glucose homeostasis.
Volume: 316
Issue: 3
Pages: E397-E409
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Publication
32540877 | J:296970
First Author: Ho KH
Year: 2020
Journal: Diabetes
Title: Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation.
Volume: 69
Issue: 9
Pages: 1936-1947
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Publication
20627083 | J:163847
First Author: Schaffer AE
Year: 2010
Journal: Dev Cell
Title: Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.
Volume: 18
Issue: 6
Pages: 1022-9
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17537793 | J:122518
First Author: Nelson SB
Year: 2007
Journal: Development
Title: The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells.
Volume: 134
Issue: 13
Pages: 2491-500
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20678473 | J:164907
First Author: Chen H
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Impaired pancreatic development in Hif2-alpha deficient mice.
Volume: 399
Issue: 3
Pages: 440-5
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21081123 | J:168019
First Author: Plank JL
Year: 2011
Journal: Dev Biol
Title: Influence and timing of arrival of murine neural crest on pancreatic beta cell development and maturation.
Volume: 349
Issue: 2
Pages: 321-30
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24477974 | J:210093
First Author: Rachdi L
Year: 2014
Journal: Diabetologia
Title: Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass.
Volume: 57
Issue: 5
Pages: 960-9
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Publication
19628478 | J:152918
First Author: Smith R
Year: 2009
Journal: Hum Mol Genet
Title: Mutant huntingtin interacts with {beta}-tubulin and disrupts vesicular transport and insulin secretion.
Volume: 18
Issue: 20
Pages: 3942-54
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Publication
32165492 | J:291485
 
First Author: Baumann D
Year: 2020
Journal: Development
Title: Role of nutrient-driven O-GlcNAc-post-translational modification in pancreatic exocrine and endocrine islet development.
Volume: 147
Issue: 7
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Publication
31682591 | J:295434
First Author: Trojanowski BM
Year: 2020
Journal: J Endocrinol
Title: Elevated β-cell stress levels promote severe diabetes development in mice with MODY4.
Volume: 244
Issue: 2
Pages: 323-337
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Publication
21388963 | J:172083
First Author: Liu J
Year: 2011
Journal: J Biol Chem
Title: Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development.
Volume: 286
Issue: 17
Pages: 15352-60
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Publication
23093780 | J:194010
First Author: Iglesias J
Year: 2012
Journal: J Clin Invest
Title: PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.
Volume: 122
Issue: 11
Pages: 4105-17
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19502415 | J:154416
First Author: Du A
Year: 2009
Journal: Diabetes
Title: Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.
Volume: 58
Issue: 9
Pages: 2059-69
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Publication
20138042 | J:236958
First Author: Lu J
Year: 2010
Journal: Gastroenterology
Title: Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.
Volume: 138
Issue: 5
Pages: 1954-65
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Publication
21852533 | J:174673
First Author: Yang YP
Year: 2011
Journal: Genes Dev
Title: Context-specific α- to-β-cell reprogramming by forced Pdx1 expression.
Volume: 25
Issue: 16
Pages: 1680-5
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Publication
26169832 | J:228228
First Author: Bonnavion R
Year: 2015
Journal: Mol Cell Biol
Title: Islet Cells Serve as Cells of Origin of Pancreatic Gastrin-Positive Endocrine Tumors.
Volume: 35
Issue: 19
Pages: 3274-83
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Publication
31923647 | J:306907
First Author: Kodani N
Year: 2020
Journal: iScience
Title: FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression.
Volume: 23
Issue: 1
Pages: 100798
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Publication
31806625 | J:284574
First Author: Moon JH
Year: 2020
Journal: Diabetes
Title: Serotonin Regulates Adult β-Cell Mass by Stimulating Perinatal β-Cell Proliferation.
Volume: 69
Issue: 2
Pages: 205-214
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Publication
31509750 | J:281075
First Author: Xue J
Year: 2019
Journal: Cell Rep
Title: CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells.
Volume: 28
Issue: 11
Pages: 2892-2904.e7
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Publication
29507125 | J:260492
First Author: Tsuchiya Y
Year: 2018
Journal: J Cell Biol
Title: IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells.
Volume: 217
Issue: 4
Pages: 1287-1301
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23271347 | J:192591
First Author: van Arensbergen J
Year: 2013
Journal: Genes Dev
Title: Ring1b bookmarks genes in pancreatic embryonic progenitors for repression in adult β cells.
Volume: 27
Issue: 1
Pages: 52-63
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Publication
23354125 | J:196410
First Author: Wakae-Takada N
Year: 2013
Journal: Diabetologia
Title: Molecular basis for the regulation of islet beta cell mass in mice: the role of E-cadherin.
Volume: 56
Issue: 4
Pages: 856-66
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Publication
25343275 | J:234890
First Author: Li F
Year: 2015
Journal: Endocrinology
Title: Conditional deletion of Men1 in the pancreatic β-cell leads to glucagon-expressing tumor development.
Volume: 156
Issue: 1
Pages: 48-57
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Publication
22187431 | J:182446
First Author: Kon N
Year: 2012
Journal: J Biol Chem
Title: Inactivation of arf-bp1 induces p53 activation and diabetic phenotypes in mice.
Volume: 287
Issue: 7
Pages: 5102-11
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Publication
27572106 | J:287368
 
First Author: Kim-Muller JY
Year: 2016
Journal: Nat Commun
Title: Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice.
Volume: 7
Pages: 12631
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Publication
37364986 | J:338878
First Author: Abarinov V
Year: 2023
Journal: Genes Dev
Title: Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain.
Volume: 37
Issue: 11-12
Pages: 490-504
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Publication
22120711 | J:186115
First Author: Lu J
Year: 2012
Journal: Oncogene
Title: Reexpression of oncoprotein MafB in proliferative β-cells and Men1 insulinomas in mouse.
Volume: 31
Issue: 31
Pages: 3647-54
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Publication
36941669 | J:334331
First Author: Melzer MK
Year: 2023
Journal: BMC Biol
Title: TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration.
Volume: 21
Issue: 1
Pages: 55
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Publication
33811703 | J:309372
First Author: Padgett LR
Year: 2021
Journal: FASEB J
Title: Deoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development.
Volume: 35
Issue: 5
Pages: e21473
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Publication
36458554 | J:333559
 
First Author: Rupani DN
Year: 2023
Journal: Development
Title: Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling.
Volume: 150
Issue: 2
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Publication
31160417 | J:278248
 
First Author: Chen C
Year: 2019
Journal: Development
Title: Evidence of a developmental origin for β-cell heterogeneity using a dual lineage-tracing technology.
Volume: 146
Issue: 13
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Publication
37739117 | J:341686
 
First Author: Mehanna S
Year: 2023
Journal: Dev Biol
Title: Beclin1 is essential for the pancreas development.
Volume: 504
Pages: 113-119
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Publication
31875961 | J:291600
First Author: Rodríguez-Seguel E
Year: 2020
Journal: J Pathol
Title: Loss of GATA4 causes ectopic pancreas in the stomach.
Volume: 250
Issue: 4
Pages: 362-373
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Publication
25063451 | J:214089
First Author: Hale MA
Year: 2014
Journal: Development
Title: The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.
Volume: 141
Issue: 16
Pages: 3123-33
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Publication
31201281 | J:280517
First Author: Spaeth JM
Year: 2019
Journal: Diabetes
Title: The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function.
Volume: 68
Issue: 9
Pages: 1806-1818
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Publication
21953612 | J:189468
First Author: Lenoir O
Year: 2011
Journal: Diabetes
Title: Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9.
Volume: 60
Issue: 11
Pages: 2861-71
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Publication
26075820 | J:225743
First Author: Um SH
Year: 2015
Journal: J Clin Invest
Title: S6K1 controls pancreatic β cell size independently of intrauterine growth restriction.
Volume: 125
Issue: 7
Pages: 2736-47
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Publication
18227155 | J:134078
First Author: Hezel AF
Year: 2008
Journal: Mol Cell Biol
Title: Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms.
Volume: 28
Issue: 7
Pages: 2414-25
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Publication
11430820 | J:70004
First Author: Scheuner D
Year: 2001
Journal: Mol Cell
Title: Translational control is required for the unfolded protein response and in vivo glucose homeostasis.
Volume: 7
Issue: 6
Pages: 1165-76
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Publication
15980866 | J:99633
First Author: Scheuner D
Year: 2005
Journal: Nat Med
Title: Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis.
Volume: 11
Issue: 7
Pages: 757-64
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Publication
36529318 | J:332289
 
First Author: Dobosz AM
Year: 2022
Journal: Mol Metab
Title: Inhibition of stearoyl-CoA desaturase 1 in the mouse impairs pancreatic islet morphogenesis and promotes loss of β-cell identity and α-cell expansion in the mature pancreas.
Volume: 67
Pages: 101659
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Publication
30487608 | J:267771
First Author: Mamidi A
Year: 2018
Journal: Nature
Title: Mechanosignalling via integrins directs fate decisions of pancreatic progenitors.
Volume: 564
Issue: 7734
Pages: 114-118
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Publication
22461559 | J:184016
First Author: Afelik S
Year: 2012
Journal: Development
Title: Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells.
Volume: 139
Issue: 10
Pages: 1744-53
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Publication
26156633 | J:225823
First Author: Martin D
Year: 2015
Journal: Dev Biol
Title: REST represses a subset of the pancreatic endocrine differentiation program.
Volume: 405
Issue: 2
Pages: 316-27
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Publication
21965615 | J:181009
First Author: Magenheim J
Year: 2011
Journal: Development
Title: Blood vessels restrain pancreas branching, differentiation and growth.
Volume: 138
Issue: 21
Pages: 4743-52
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Publication
32332159 | J:293253
First Author: Osipovich AB
Year: 2020
Journal: Diabetes
Title: Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells.
Volume: 69
Issue: 7
Pages: 1476-1491
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