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Search results 101 to 178 out of 178 for Uck1

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0.028s
Type Details Score
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1646922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Image: EH988; Specimen C2511
Specimen Label: EH988; Specimen C2511
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736222
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1683322
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1700022
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1832122
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310480
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423803
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EH988; Specimen C2511
Detected: false
Specimen Num: 1
Publication
First Author: Eddleston J
Year: 1999
Journal: Genomics
Title: Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp).
Volume: 56
Issue: 2
Pages: 149-59
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
Protein Domain
Type: Family
Description: Uridine-cytidine kinase (UCK), also known as uridine kinase, phosphorylates uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) []. UCK is the rate-limiting enzyme in the pyrimidine-nucleotide salvage pathway. It also catalyses the phosphorylation of several cytotoxic ribonucleoside analogs that have been investigated for possible use as chemotherapeutic agents for treatment of cancer [, , ].Two UCKs with 70% sequence identity have been reported in human: UCK1 and UCK2. This entry represents UCK1. The biological role of UCK1 remains unknown, as UCK2 is responsible for the majority or uridine and cytidine phosphorylation in cells [, ].
Publication
First Author: Van Rompay AR
Year: 2001
Journal: Mol Pharmacol
Title: Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.
Volume: 59
Issue: 5
Pages: 1181-6
Publication
First Author: Suzuki NN
Year: 2004
Journal: Structure
Title: Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase.
Volume: 12
Issue: 5
Pages: 751-64
Publication
First Author: Kang GJ
Year: 1989
Journal: J Biol Chem
Title: Cyclopentenylcytosine triphosphate. Formation and inhibition of CTP synthetase.
Volume: 264
Issue: 2
Pages: 713-8
Publication
First Author: Koizumi K
Year: 2001
Journal: Int J Mol Med
Title: Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells.
Volume: 8
Issue: 3
Pages: 273-8
Publication
First Author: van Kuilenburg AB
Year: 2016
Journal: Biochim Biophys Acta
Title: The pivotal role of uridine-cytidine kinases in pyrimidine metabolism and activation of cytotoxic nucleoside analogues in neuroblastoma.
Volume: 1862
Issue: 9
Pages: 1504-12
Publication
First Author: Kaneko S
Year: 1998
Journal: Gene
Title: Cloning, sequence analysis and expression of the basidiomycete Lentinus edodes gene uck1, encoding UMP-CMP kinase, the homologue of Saccharomyces cerevisae URA6 gene.
Volume: 211
Issue: 2
Pages: 259-66
Publication
First Author: Appleby TC
Year: 2005
Journal: Acta Crystallogr D Biol Crystallogr
Title: Structure of human uridine-cytidine kinase 2 determined by SIRAS using a rotating-anode X-ray generator and a single samarium derivative.
Volume: 61
Issue: Pt 3
Pages: 278-84
Publication
First Author: Suzuki NN
Year: 2003
Journal: Acta Crystallogr D Biol Crystallogr
Title: Crystallization and preliminary X-ray analysis of human uridine-cytidine kinase 2.
Volume: 59
Issue: Pt 8
Pages: 1477-8
Protein Domain
Type: Family
Description: Uridine-cytidine kinase (UCK), also known as uridine kinase, phosphorylates uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) []. UCK is the rate-limiting enzyme in the pyrimidine-nucleotide salvage pathway. It also catalyses the phosphorylation of several cytotoxic ribonucleoside analogs that have been investigated for possible use as chemotherapeutic agents for treatment of cancer [, , ].Two UCKs with 70% sequence identity have been reported in human: UCK1 and UCK2 []. This entry represents UCK2. UCK2 is responsible for the majority or uridine and cytidine phosphorylation in cells [, ]. It is overexpressed in some cancer cells and could be used as a target for antitumour and antiviral drugs []. The structure of UCK2 has been solved [, ].
Protein
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 283  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false