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Search results 1 to 100 out of 174 for Abca4

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Category: Publication
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Type Details Score
Publication
22735453 | J:225104
 
First Author: Quazi F
Year: 2012
Journal: Nat Commun
Title: ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer.
Volume: 3
Pages: 925
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Publication
24576873 | J:229504
First Author: Wu L
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Light damage in Abca4 and Rpe65rd12 mice.
Volume: 55
Issue: 3
Pages: 1910-8
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Publication
22886305 | J:191429
First Author: Han Z
Year: 2012
Journal: J Clin Invest
Title: DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice.
Volume: 122
Issue: 9
Pages: 3221-6
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Publication
9202155 | J:48634
First Author: Azarian SM
Year: 1997
Journal: FEBS Lett
Title: The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt's disease (ABCR).
Volume: 409
Issue: 2
Pages: 247-52
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Publication
10412977 | J:56317
First Author: Weng J
Year: 1999
Journal: Cell
Title: Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice.
Volume: 98
Issue: 1
Pages: 13-23
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Publication
10852960 | J:62911
First Author: Mata NL
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration.
Volume: 97
Issue: 13
Pages: 7154-9
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Publication
26720470 | J:231027
First Author: Müller PL
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Monoallelic ABCA4 Mutations Appear Insufficient to Cause Retinopathy: A Quantitative Autofluorescence Study.
Volume: 56
Issue: 13
Pages: 8179-86
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Publication
30397118 | J:267256
First Author: Lenis TL
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration.
Volume: 115
Issue: 47
Pages: E11120-E11127
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Publication
22033104 | J:185019
First Author: Conley SM
Year: 2012
Journal: Biochim Biophys Acta
Title: Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy.
Volume: 1822
Issue: 7
Pages: 1169-79
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Publication
29847651 | J:281937
First Author: Paavo M
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Mutations in GPR143/OA1 and ABCA4 Inform Interpretations of Short-Wavelength and Near-Infrared Fundus Autofluorescence.
Volume: 59
Issue: 6
Pages: 2459-2469
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Publication
19553623 | J:154653
First Author: Maeda A
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina.
Volume: 50
Issue: 11
Pages: 5435-43
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Publication
29145636 | J:255529
First Author: Molday LL
Year: 2018
Journal: Hum Mol Genet
Title: Localization and functional characterization of the p.Asn965Ser (N965S) ABCA4 variant in mice reveal pathogenic mechanisms underlying Stargardt macular degeneration.
Volume: 27
Issue: 2
Pages: 295-306
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Publication
24707049 | J:208864
First Author: Quazi F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: ATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11-cis-retinal.
Volume: 111
Issue: 13
Pages: 5024-9
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Publication
26106163 | J:223731
First Author: Charbel Issa P
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization.
Volume: 112
Issue: 27
Pages: 8415-20
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Publication
36359858 | J:331432
 
First Author: Ng ESY
Year: 2022
Journal: Cells
Title: Membrane Attack Complex Mediates Retinal Pigment Epithelium Cell Death in Stargardt Macular Degeneration.
Volume: 11
Issue: 21
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Publication
29229934 | J:280356
First Author: Anderson DMG
Year: 2017
Journal: Sci Rep
Title: Bis(monoacylglycero)phosphate lipids in the retinal pigment epithelium implicate lysosomal/endosomal dysfunction in a model of Stargardt disease and human retinas.
Volume: 7
Issue: 1
Pages: 17352
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Publication
18235027 | J:132587
First Author: Liu J
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery.
Volume: 49
Issue: 2
Pages: 772-80
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Publication
33137194 | J:298298
First Author: Meleppat RK
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: In Situ Morphologic and Spectral Characterization of Retinal Pigment Epithelium Organelles in Mice Using Multicolor Confocal Fluorescence Imaging.
Volume: 61
Issue: 13
Pages: 1
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Publication
26420842 | J:226542
First Author: Trapani I
Year: 2015
Journal: Hum Mol Genet
Title: Improved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease.
Volume: 24
Issue: 23
Pages: 6811-25
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Publication
16638746 | J:114357
First Author: Bui TV
Year: 2006
Journal: J Biol Chem
Title: Characterization of native retinal fluorophores involved in biosynthesis of A2E and lipofuscin-associated retinopathies.
Volume: 281
Issue: 26
Pages: 18112-9
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15067110 | J:89615
First Author: Radu RA
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration.
Volume: 101
Issue: 16
Pages: 5928-33
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Publication
31989709 | J:304072
First Author: Fang Y
Year: 2020
Journal: FASEB J
Title: Fundus autofluorescence, spectral-domain optical coherence tomography, and histology correlations in a Stargardt disease mouse model.
Volume: 34
Issue: 3
Pages: 3693-3714
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Publication
21156790 | J:170397
First Author: Ma L
Year: 2011
Journal: J Biol Chem
Title: C20-D3-vitamin A slows lipofuscin accumulation and electrophysiological retinal degeneration in a mouse model of Stargardt disease.
Volume: 286
Issue: 10
Pages: 7966-74
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Publication
18515570 | J:141801
First Author: Radu RA
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation.
Volume: 49
Issue: 9
Pages: 3821-9
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21721517 | J:176983
First Author: Tsybovsky Y
Year: 2011
Journal: Biochemistry
Title: Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4.
Volume: 50
Issue: 32
Pages: 6855-66
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Publication
21435020 | J:331783
First Author: Li Q
Year: 2011
Journal: Exp Dermatol
Title: Expression of the Abca-subfamily of genes in Abcc6-/- mice--upregulation of Abca4.
Volume: 20
Issue: 5
Pages: 452-4
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Publication
23840644 | J:203718
First Author: Anderson OA
Year: 2013
Journal: PLoS One
Title: A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome.
Volume: 8
Issue: 6
Pages: e67263
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Publication
29773803 | J:262864
First Author: Chen Y
Year: 2018
Journal: Nat Commun
Title: A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.
Volume: 9
Issue: 1
Pages: 1976
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Publication
22039245 | J:191397
First Author: Yamamoto K
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: A novel bisretinoid of retina is an adduct on glycerophosphoethanolamine.
Volume: 52
Issue: 12
Pages: 9084-90
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Publication
22570475 | J:331434
First Author: Boyer NP
Year: 2012
Journal: J Biol Chem
Title: Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.
Volume: 287
Issue: 26
Pages: 22276-86
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Publication
21464132 | J:173786
First Author: Radu RA
Year: 2011
Journal: J Biol Chem
Title: Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration.
Volume: 286
Issue: 21
Pages: 18593-601
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Publication
22786896 | J:213974
First Author: Secondi R
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Fundus autofluorescence findings in a mouse model of retinal detachment.
Volume: 53
Issue: 9
Pages: 5190-7
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Publication
19478335 | J:152624
First Author: Wu Y
Year: 2009
Journal: J Biol Chem
Title: Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease.
Volume: 284
Issue: 30
Pages: 20155-66
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Publication
25712131 | J:221141
First Author: Zhang N
Year: 2015
Journal: Hum Mol Genet
Title: Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.
Volume: 24
Issue: 11
Pages: 3220-37
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26468292 | J:276301
First Author: Perusek L
Year: 2015
Journal: J Biol Chem
Title: Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium.
Volume: 290
Issue: 48
Pages: 29035-44
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Publication
19304658 | J:150515
First Author: Maeda A
Year: 2009
Journal: J Biol Chem
Title: Involvement of all-trans-retinal in acute light-induced retinopathy of mice.
Volume: 284
Issue: 22
Pages: 15173-83
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Publication
28348233 | J:242022
First Author: Lenis TL
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease.
Volume: 114
Issue: 15
Pages: 3987-3992
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32265302 | J:292103
First Author: Liao C
Year: 2020
Journal: J Biol Chem
Title: Activation of JNK signaling promotes all-trans-retinal-induced photoreceptor apoptosis in mice.
Volume: 295
Issue: 20
Pages: 6958-6971
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25970164 | J:278265
First Author: Bavik C
Year: 2015
Journal: PLoS One
Title: Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity.
Volume: 10
Issue: 5
Pages: e0124940
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31319418 | J:277705
First Author: Lu W
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Oral Delivery of the P2Y12 Receptor Antagonist Ticagrelor Prevents Loss of Photoreceptors in an ABCA4-/- Mouse Model of Retinal Degeneration.
Volume: 60
Issue: 8
Pages: 3046-3053
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Publication
34376700 | J:313876
First Author: Meleppat RK
Year: 2021
Journal: Sci Rep
Title: In vivo multimodal retinal imaging of disease-related pigmentary changes in retinal pigment epithelium.
Volume: 11
Issue: 1
Pages: 16252
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18048333 | J:128487
First Author: Kim SR
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model.
Volume: 104
Issue: 49
Pages: 19273-8
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27432952 | J:234395
First Author: Tan LX
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Protective responses to sublytic complement in the retinal pigment epithelium.
Volume: 113
Issue: 31
Pages: 8789-94
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21357388 | J:181440
First Author: Grey AC
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Spatial localization of A2E in the retinal pigment epithelium.
Volume: 52
Issue: 7
Pages: 3926-33
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11431429 | J:70248
First Author: Mata NL
Year: 2001
Journal: Invest Ophthalmol Vis Sci
Title: Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration.
Volume: 42
Issue: 8
Pages: 1685-90
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22639870 | J:187447
First Author: Guha S
Year: 2012
Journal: J Neurochem
Title: Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.
Volume: 122
Issue: 4
Pages: 823-33
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18085472 | J:130834
First Author: Qtaishat NM
Year: 2007
Journal: Curr Eye Res
Title: Preservation of retinoid influx into eye tissues of ABCR-deficient mice.
Volume: 32
Issue: 12
Pages: 1073-82
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29725296 | J:280304
 
First Author: Lu W
Year: 2018
Journal: Front Pharmacol
Title: The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration.
Volume: 9
Pages: 242
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15870200 | J:99240
First Author: Fishkin NE
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate.
Volume: 102
Issue: 20
Pages: 7091-6
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16411761 | J:106138
First Author: Maiti P
Year: 2006
Journal: Biochemistry
Title: Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation.
Volume: 45
Issue: 3
Pages: 852-60
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23548623 | J:215296
First Author: Sparrow JR
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Quantitative fundus autofluorescence in mice: correlation with HPLC quantitation of RPE lipofuscin and measurement of retina outer nuclear layer thickness.
Volume: 54
Issue: 4
Pages: 2812-20
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23964074 | J:203956
First Author: Guha S
Year: 2013
Journal: FASEB J
Title: Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor.
Volume: 27
Issue: 11
Pages: 4500-9
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18263807 | J:136885
First Author: Pawar AS
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Recovery of rod photoresponses in ABCR-deficient mice.
Volume: 49
Issue: 6
Pages: 2743-55
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Publication
23761084 | J:214191
First Author: Charbel Issa P
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology.
Volume: 54
Issue: 8
Pages: 5602-12
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30126999 | J:265537
First Author: Kaur G
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration.
Volume: 115
Issue: 36
Pages: 9014-9019
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23211825 | J:214581
First Author: Dobri N
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: A1120, a nonretinoid RBP4 antagonist, inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis.
Volume: 54
Issue: 1
Pages: 85-95
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29860462 | J:263183
First Author: Prokopiou E
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Omega-3 Fatty Acids Supplementation: Therapeutic Potential in a Mouse Model of Stargardt Disease.
Volume: 59
Issue: 7
Pages: 2757-2767
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9490294 | J:45816
First Author: Nasonkin I
Year: 1998
Journal: Hum Genet
Title: Mapping of the rod photoreceptor ABC transporter (ABCR) to 1p21-p22.1 and identification of novel mutations in Stargardt's disease.
Volume: 102
Issue: 1
Pages: 21-6
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33187113 | J:303513
 
First Author: Jabri Y
Year: 2020
Journal: Int J Mol Sci
Title: Cell-Type-Specific Complement Profiling in the ABCA4-/- Mouse Model of Stargardt Disease.
Volume: 21
Issue: 22
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17032653 | J:117483
First Author: Maeda A
Year: 2006
Journal: J Biol Chem
Title: Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice.
Volume: 281
Issue: 49
Pages: 37697-704
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28302729 | J:242772
First Author: Reyes-Reveles J
Year: 2017
Journal: J Biol Chem
Title: Phagocytosis-dependent ketogenesis in retinal pigment epithelium.
Volume: 292
Issue: 19
Pages: 8038-8047
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Publication
15277666 | J:99461
First Author: Kim SR
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E.
Volume: 101
Issue: 32
Pages: 11668-72
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27274068 | J:234295
First Author: Ueda K
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Photodegradation of retinal bisretinoids in mouse models and implications for macular degeneration.
Volume: 113
Issue: 25
Pages: 6904-9
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29871924 | J:267104
First Author: Racz B
Year: 2018
Journal: J Biol Chem
Title: A non-retinoid antagonist of retinol-binding protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle.
Volume: 293
Issue: 29
Pages: 11574-11588
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28395299 | J:258464
First Author: Zhao J
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Multimodal Fundus Imaging of Sodium Iodate-Treated Mice Informs RPE Susceptibility and Origins of Increased Fundus Autofluorescence.
Volume: 58
Issue: 4
Pages: 2152-2159
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24231350 | J:207755
First Author: Chen Y
Year: 2013
Journal: J Clin Invest
Title: Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration.
Volume: 123
Issue: 12
Pages: 5119-34
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25414195 | J:230293
First Author: Zhao J
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Preparative and biosynthetic insights into pdA2E and isopdA2E, retinal-derived fluorophores of retinal pigment epithelial lipofuscin.
Volume: 55
Issue: 12
Pages: 8241-50
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28192797 | J:257639
First Author: Zhao J
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Aberrant Buildup of All-Trans-Retinal Dimer, a Nonpyridinium Bisretinoid Lipofuscin Fluorophore, Contributes to the Degeneration of the Retinal Pigment Epithelium.
Volume: 58
Issue: 2
Pages: 1063-1075
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26075817 | J:225430
First Author: Zhang J
Year: 2015
Journal: J Clin Invest
Title: Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
Volume: 125
Issue: 7
Pages: 2781-94
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Publication
18658157 | J:142322
First Author: Maeda A
Year: 2008
Journal: J Biol Chem
Title: Retinopathy in mice induced by disrupted all-trans-retinal clearance.
Volume: 283
Issue: 39
Pages: 26684-93
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30038866 | J:280303
 
First Author: Taubitz T
Year: 2018
Journal: PeerJ
Title: Ultrastructural alterations in the retinal pigment epithelium and photoreceptors of a Stargardt patient and three Stargardt mouse models: indication for the central role of RPE melanin in oxidative stress.
Volume: 6
Pages: e5215
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24712709 | J:213619
First Author: Wu Y
Year: 2014
Journal: Biochem J
Title: Retinal metabolism in humans induces the formation of an unprecedented lipofuscin fluorophore 'pdA2E'.
Volume: 460
Issue: 3
Pages: 343-52
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24706818 | J:208628
First Author: Nociari MM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium.
Volume: 111
Issue: 14
Pages: E1402-8
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22184108 | J:182451
First Author: Chen Y
Year: 2012
Journal: J Biol Chem
Title: Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration.
Volume: 287
Issue: 7
Pages: 5059-69
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Publication
33154094 | J:331629
First Author: Ortega JT
Year: 2021
Journal: Mol Pharmacol
Title: Protective Effects of Flavonoids in Acute Models of Light-Induced Retinal Degeneration.
Volume: 99
Issue: 1
Pages: 60-77
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Publication
26225634 | J:230948
First Author: Schur RM
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Manganese-Enhanced MRI for Preclinical Evaluation of Retinal Degeneration Treatments.
Volume: 56
Issue: 8
Pages: 4936-42
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Publication
22198730 | J:280311
First Author: Maeda A
Year: 2011
Journal: Nat Chem Biol
Title: Primary amines protect against retinal degeneration in mouse models of retinopathies.
Volume: 8
Issue: 2
Pages: 170-8
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30018116 | J:280617
First Author: Gao S
Year: 2018
Journal: Mol Pharmacol
Title: Protective Effect of a Locked Retinal Chromophore Analog against Light-Induced Retinal Degeneration.
Volume: 94
Issue: 4
Pages: 1132-1144
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Publication
25617130 | J:280312
 
First Author: Puntel A
Year: 2015
Journal: Biomaterials
Title: Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles.
Volume: 44
Pages: 103-10
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Publication
34863682 | J:319666
 
First Author: Tao L
Year: 2022
Journal: Exp Eye Res
Title: Repressing c-Jun N-terminal kinase signaling mitigates retinal pigment epithelium degeneration in mice with failure to clear all-trans-retinal.
Volume: 214
Pages: 108877
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Publication
29162627 | J:280317
First Author: Orban T
Year: 2018
Journal: J Pharmacol Exp Ther
Title: A Combination of G Protein-Coupled Receptor Modulators Protects Photoreceptors from Degeneration.
Volume: 364
Issue: 2
Pages: 207-220
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Publication
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