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Search results 801 to 900 out of 1539 for Cat

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Protein Domain
Type: Family
Description: This family is a member of the Class IIA subfamily of the haloacid dehalogenase superfamily of aspartate-nucleophile hydrolases. Sequences in this family are all from eukaryotes. One sequence is called "Cat Eye Syndrome critical region protein 5"(CECR5) []. This gene has been cloned from a pericentromere region of human chromosome 22 believed to be the location of the gene or genes responsible for Cat Eye Syndrome. This is one of a number of candidate genes. The Schizosaccharomyces pombe (Fission yeast) sequence is annotated as "phosphatidyl synthase,"however this is due entirely to a C-terminal region of the protein (outside the region of similarity covered by this entry) which is highly homologous to a family of CDP-alcohol phosphatidyltransferases. The physical connection of the phosphatidyl synthase and the HAD-superfamily hydrolase domain in S. pombe may, however, be an important clue to the substrate for the hydrolases in this group.
Protein Domain
Type: Homologous_superfamily
Description: Chloramphenicol acetyltransferase (CAT) catalyses the acetyl-CoA dependent acetylation of chloramphenicol, resulting in the inactivation of the antibiotic. The crystal structure of the type III enzyme from Escherichia coli with chloramphenicol bound has been determined. CAT is a trimer of identical subunits (monomer Mr 25,000) and the trimeric structure is stabilised by a number of hydrogen bonds, some of which result in the extension of a β-sheet across the subunit interface. Chloramphenicol binds in a deep pocket located at the boundary between adjacent subunits of the trimer, such that the majority of residues forming the binding pocket belong to one subunit while the catalytically essential histidine belongs to the adjacent subunit. His195 is appropriately positioned to act as a general base catalyst in the reaction, and the required tautomeric stabilisation is provided by an unusual interaction with a main-chain carbonyl oxygen [].This superfamily represents a domain characteristic of trimeric enzymes with the active sites being located in between subunits, including chloramphenicol acetyltransferase.
Publication
First Author: Suzuki A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs.
Volume: 107
Issue: 8
Pages: 3594-9
Publication
First Author: Parlakian A
Year: 2004
Journal: Mol Cell Biol
Title: Targeted inactivation of serum response factor in the developing heart results in myocardial defects and embryonic lethality.
Volume: 24
Issue: 12
Pages: 5281-9
Publication
First Author: Yasuda T
Year: 2016
Journal: J Clin Invest
Title: Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis.
Volume: 126
Issue: 6
Pages: 2064-76
Publication
First Author: Laurie LE
Year: 2016
Journal: PLoS One
Title: The Transcription Factor Hand1 Is Involved In Runx2-Ihh-Regulated Endochondral Ossification.
Volume: 11
Issue: 2
Pages: e0150263
Publication
First Author: Schweizer U
Year: 2002
Journal: J Cell Biol
Title: Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult.
Volume: 156
Issue: 2
Pages: 287-97
Publication
First Author: Haigh JJ
Year: 2000
Journal: Development
Title: Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state.
Volume: 127
Issue: 7
Pages: 1445-53
Publication
First Author: Yamauchi Y
Year: 1999
Journal: Dev Biol
Title: A novel transgenic technique that allows specific marking of the neural crest cell lineage in mice.
Volume: 212
Issue: 1
Pages: 191-203
Publication
First Author: Ishii Y
Year: 2006
Journal: J Neurochem
Title: Mouse brains deficient in neuronal PDGF receptor-beta develop normally but are vulnerable to injury.
Volume: 98
Issue: 2
Pages: 588-600
Publication
First Author: Holzenberger M
Year: 2000
Journal: Genesis
Title: Ubiquitous postnatal LoxP recombination using a doxycycline auto-inducible Cre transgene (DAI-Cre).
Volume: 26
Issue: 2
Pages: 157-9
Publication  
First Author: Ohi Y
Year: 2007
Journal: Brain Res
Title: Platelet-derived growth factor (PDGF)-BB inhibits AMPA receptor-mediated synaptic transmission via PDGF receptor-beta in murine nucleus tractus solitarius.
Volume: 1159
Pages: 77-85
Publication
First Author: Mitsui S
Year: 2007
Journal: Cereb Cortex
Title: A transcriptional enhancer that directs telencephalon-specific transgene expression in mouse brain.
Volume: 17
Issue: 3
Pages: 522-30
Publication
First Author: Yun K
Year: 2018
Journal: PLoS One
Title: Constitutive metanephric mesenchyme-specific expression of interferon-gamma causes renal dysplasia by regulating Sall1 expression.
Volume: 13
Issue: 5
Pages: e0197356
Publication
First Author: Zhang QY
Year: 2017
Journal: Hepatology
Title: The novel intracellular protein CREG inhibits hepatic steatosis, obesity, and insulin resistance.
Volume: 66
Issue: 3
Pages: 834-854
Publication
First Author: Ye P
Year: 2019
Journal: Hepatology
Title: Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression.
Volume: 69
Issue: 5
Pages: 1946-1964
Publication
First Author: Schuler M
Year: 2005
Journal: Genesis
Title: Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouse.
Volume: 41
Issue: 4
Pages: 165-70
Publication
First Author: Kelavkar UP
Year: 2006
Journal: Neoplasia
Title: Conditional expression of human 15-lipoxygenase-1 in mouse prostate induces prostatic intraepithelial neoplasia: the FLiMP mouse model.
Volume: 8
Issue: 6
Pages: 510-22
Publication  
First Author: Okubo Y
Year: 2021
Journal: Development
Title: Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways.
Volume: 148
Issue: 19
Publication
First Author: Hoesl E
Year: 2008
Journal: J Mol Cell Cardiol
Title: Tamoxifen-inducible gene deletion in the cardiac conduction system.
Volume: 45
Issue: 1
Pages: 62-9
Publication
First Author: Noda K
Year: 2014
Journal: PLoS One
Title: Rho-kinase inhibition ameliorates metabolic disorders through activation of AMPK pathway in mice.
Volume: 9
Issue: 11
Pages: e110446
Publication
First Author: Dewachter I
Year: 2002
Journal: J Neurosci
Title: Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
Volume: 22
Issue: 9
Pages: 3445-53
Publication
First Author: Kallenborn-Gerhardt W
Year: 2012
Journal: J Neurosci
Title: NADPH oxidase-4 maintains neuropathic pain after peripheral nerve injury.
Volume: 32
Issue: 30
Pages: 10136-45
Publication
First Author: Jiang X
Year: 2015
Journal: Hypertension
Title: Tumor necrosis factor receptor-associated factor 3 is a positive regulator of pathological cardiac hypertrophy.
Volume: 66
Issue: 2
Pages: 356-67
Publication
First Author: Zhang X
Year: 2020
Journal: J Am Heart Assoc
Title: NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity.
Volume: 9
Issue: 16
Pages: e016419
Publication
First Author: Sato M
Year: 2005
Journal: Mol Reprod Dev
Title: Production of CETD transgenic mouse line allowing ablation of any type of specific cell population.
Volume: 72
Issue: 1
Pages: 54-67
Publication
First Author: Zhou Z
Year: 2015
Journal: Dev Cell
Title: RNA Binding Protein Nanos2 Organizes Post-transcriptional Buffering System to Retain Primitive State of Mouse Spermatogonial Stem Cells.
Volume: 34
Issue: 1
Pages: 96-107
Publication
First Author: Niimi Y
Year: 2019
Journal: Dev Biol
Title: Essential role of mouse Dead end1 in the maintenance of spermatogonia.
Volume: 445
Issue: 1
Pages: 103-112
Strain
Attribute String: congenic, targeted mutation, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, endonuclease-mediated mutation, congenic
Strain
Attribute String: mutant strain, congenic, targeted mutation, endonuclease-mediated mutation
Publication
First Author: Kotredes KP
Year: 2024
Journal: Alzheimers Dement
Title: Characterizing molecular and synaptic signatures in mouse models of late-onset Alzheimer's disease independent of amyloid and tau pathology.
Volume: 20
Issue: 6
Pages: 4126-4146
Publication  
First Author: Chen Y
Year: 2019
Journal: J Neuroimmunol
Title: Oxymatrine can attenuate pathological deficits of Alzheimer's disease mice through regulation of neuroinflammation.
Volume: 334
Pages: 576978
Strain
Attribute String: endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Mesp1/Mesp1<+> Rbpj/Rbpj Tg(CAG-cat,-Notch1)1Ysa/?
Background: involves: 129P2/OlaHsd * C3H * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mesp1/Mesp1<+> Pofut1/Pofut1 Tg(CAG-cat,-Notch1)1Ysa/?
Background: involves: C3H * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Aplp2/Aplp2 App/App
Background: involves: 129/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: App/App
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-TBX3)1Vmc/? Tg(Myh6-cre)2182Mds/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-TBX3)1Vmc/? Tg(Nppa-cre)m-3+4Vmc/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-ALOX15)1868Klv/? Tg(Pbsn-cre)4Prb/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-ALOX15)1868Klv/Tg(CAG-cat,-ALOX15)1868Klv Tg(Pbsn-cre)4Prb/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Speer6-ps1/Speer6-ps1<+> Tg(CAG-cat,-Creg1)#Yal/?
Background: involves: C57BL/6J * DBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: A1cf/A1cf<+> Tg(CAG-cat,-Dusp14)4Lyg/?
Background: involves: C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: A1cf/A1cf<+> Tg(CAG-cat,-Tcf25)1Xdgz/?
Background: involves: C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Mpz-cre)94Imeg/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)1Brn/? Tg(GFAP-cre)25Mes/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Tek-cre)1Ywa/?
Background: involves: C57BL/6 * DBA/2 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)1Brn/? Tg(Pomc-cre)5Brn/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(DBH-cre)6-8Koba/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(DBH-cre)9-9Koba/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(rtetR-tetO-cre)1Mhz/?
Background: involves: C57BL/6 * CBA * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Dkk3-cre)D9Tfur/?
Background: involves: C3H * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Grin2c-cre/PGR)25Mim/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Icam5-cre)DYyos/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Myh7-cre)1Zli/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Nes-cre/Esr1*)4Ynj/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tagln/Tagln<+> Tg(CAG-cat,-lacZ)1Brn/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)1Brn/? Tg(Tagln-cre/ERT2)1Feil/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Rr437-cre)#Hmd/?
Background: involves: C3H * C57BL/6 * C57BL/6J * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Nes-cre)1Nogu/? Tg(CAG-cat,-lacZ)34Pva/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Grp/Grp<+> Tg(CAG-cat,-lacZ)34Pva/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(NES-cre)#Ajde/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Chx10-cre)5Tfur/?
Background: involves: C3H * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Crx-cre/ERT2)1Tfur/?
Background: involves: C3H * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Goulet B
Year: 2004
Journal: Mol Cell
Title: A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor.
Volume: 14
Issue: 2
Pages: 207-19
Publication
First Author: Chiariotti L
Year: 1991
Journal: Biochim Biophys Acta
Title: Structure and expression of the negative growth factor mouse beta-galactoside binding protein gene.
Volume: 1089
Issue: 1
Pages: 54-60
Publication
First Author: Singh IS
Year: 1991
Journal: Biochem Biophys Res Commun
Title: Molecular cloning and characterization of the promoter region of the mouse regulatory subunit RII beta of type II cAMP-dependent protein kinase.
Volume: 178
Issue: 1
Pages: 221-6
Publication
First Author: Nanba E
Year: 1991
Journal: Biochem Biophys Res Commun
Title: Organization of the mouse acid beta-galactosidase gene.
Volume: 178
Issue: 1
Pages: 158-64
Publication
First Author: Li F
Year: 2021
Journal: Cell
Title: Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem.
Volume: 184
Issue: 14
Pages: 3762-3773.e10
Publication
First Author: Patwardhan S
Year: 1991
Journal: Oncogene
Title: EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.
Volume: 6
Issue: 6
Pages: 917-28
Publication
First Author: Tulchinsky EM
Year: 1990
Journal: Gene
Title: Structure of gene mts1, transcribed in metastatic mouse tumor cells.
Volume: 87
Issue: 2
Pages: 219-23
Publication
First Author: Shibuya N
Year: 2009
Journal: Antioxid Redox Signal
Title: 3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain.
Volume: 11
Issue: 4
Pages: 703-14
Publication
First Author: Bernard O
Year: 1996
Journal: Genomics
Title: Structure and chromosomal localization of the genomic locus encoding the Kiz1 LIM-kinase gene.
Volume: 35
Issue: 3
Pages: 593-6
Publication
First Author: Steiner F
Year: 1998
Journal: Genomics
Title: Structure and expression of the gene encoding murine M-protein, a sarcomere-specific member of the immunoglobulin superfamily.
Volume: 49
Issue: 1
Pages: 83-95
Publication
First Author: Engert JC
Year: 1995
Journal: Nucleic Acids Res
Title: Activation of a muscle-specific enhancer by the Ski proto-oncogene.
Volume: 23
Issue: 15
Pages: 2988-94
Publication
First Author: Muggleton-Harris AL
Year: 1987
Journal: Development
Title: Rescue of developmental lens abnormalities in chimaeras of noncataractous and congenital cataractous mice.
Volume: 99
Issue: 4
Pages: 473-80
Publication
First Author: Sukhova GK
Year: 2003
Journal: J Clin Invest
Title: Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice.
Volume: 111
Issue: 6
Pages: 897-906
Publication
First Author: Maehr R
Year: 2005
Journal: J Clin Invest
Title: Cathepsin L is essential for onset of autoimmune diabetes in NOD mice.
Volume: 115
Issue: 10
Pages: 2934-43
Publication
First Author: Shi GP
Year: 2003
Journal: Circ Res
Title: Deficiency of the cysteine protease cathepsin S impairs microvessel growth.
Volume: 92
Issue: 5
Pages: 493-500
Publication
First Author: Yang H
Year: 2005
Journal: J Immunol
Title: Cathepsin S is required for murine autoimmune myasthenia gravis pathogenesis.
Volume: 174
Issue: 3
Pages: 1729-37
Publication
First Author: Dey S
Year: 2015
Journal: Cell
Title: Cyclic Regulation of Sensory Perception by a Female Hormone Alters Behavior.
Volume: 161
Issue: 6
Pages: 1334-44
Publication
First Author: Sherr CJ
Year: 1985
Journal: Cell
Title: The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1.
Volume: 41
Issue: 3
Pages: 665-76
Publication
First Author: Kobayashi Y
Year: 2001
Journal: J Vet Med Sci
Title: Molecular cloning of feline hepatocyte growth factor (HGF) cDNA.
Volume: 63
Issue: 2
Pages: 211-4
Publication
First Author: Bienz-Tadmor B
Year: 1985
Journal: EMBO J
Title: The 5' region of the p53 gene: evolutionary conservation and evidence for a negative regulatory element.
Volume: 4
Issue: 12
Pages: 3209-13
Publication
First Author: Gilbert DA
Year: 1988
Journal: Genomics
Title: Chromosomal mapping of lysosomal enzyme structural genes in the domestic cat.
Volume: 2
Issue: 4
Pages: 329-36
Publication
First Author: Breuer B
Year: 1989
Journal: Gene
Title: Cloning and characterization of the mouse histone H1(0) promoter region.
Volume: 81
Issue: 2
Pages: 307-14