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Search results 201 to 216 out of 216 for Haus6

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0.023s
Type Details Score
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: false
Publication
First Author: Einarson MB
Year: 2004
Journal: Mol Cell Biol
Title: Human enhancer of invasion-cluster, a coiled-coil protein required for passage through mitosis.
Volume: 24
Issue: 9
Pages: 3957-71
Protein Domain
Type: Family
Description: Assembly of a robust microtubule-based mitotic spindle is essential foraccurate segregation of chromosomes to progeny []. Spindle assembly relies on the concerted action of centrosomes, spindle microtubules, molecular motors and non-motor spindle proteins []. A number of novel regulators of spindle assembly have been identified: one of these is HAUS, an 8-subunit protein complex that shares similarity with Drosophila Augmin [, ]. Plants also have a augmin complex consisting of eight subunits. Subunits AUG1 to AUG6 can be aligned with the human HAUS1 to HAUS6 proteins [].HAUS localises to interphase centrosomes and to mitotic spindle micro- tubules; its disruption induces microtubule-dependent fragmentation of centrosomes, and an increase in centrosome size. HAUS disruption results in the destabilisation of kinetochore microtubules and eventual formation of multipolar spindles. Such severe mitotic defects are alleviated by co-depletion of NuMA, indicating that both factors regulate opposing activities. HAUS disruption alters NuMA localisation, suggesting that mis-localised NuMA activity contributes to the observed spindle and centrosome defects. The Augmin complex (HAUS) is thus a critical, evolutionarily conserved multi-subunit protein complex that regulates centrosome and spindle integrity [].The HAUS (Homologous to AUgmin Subunits) individual subunits have been designated HAUS1 to HAUS8 []. HAUS augmin-like complex subunit 1 (also known as enhancer of invasion-cluster, HEI-C [], and coiled-coil domain-containing protein 5) is a coiled-coil protein required for passage through mitosis [].
Publication
First Author: Hotta T
Year: 2012
Journal: Plant Cell
Title: Characterization of the Arabidopsis augmin complex uncovers its critical function in the assembly of the acentrosomal spindle and phragmoplast microtubule arrays.
Volume: 24
Issue: 4
Pages: 1494-509
Publication
First Author: Uehara R
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.
Volume: 106
Issue: 17
Pages: 6998-7003
Publication
First Author: Lawo S
Year: 2009
Journal: Curr Biol
Title: HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.
Volume: 19
Issue: 10
Pages: 816-26