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Search results 201 to 272 out of 272 for Thpo

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Type Details Score
Publication
30664659 | J:270484
First Author: Song Y
Year: 2019
Journal: Nat Commun
Title: A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies.
Volume: 10
Issue: 1
Pages: 366
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Publication
27723723 | J:240722
First Author: Das R
Year: 2016
Journal: Nat Med
Title: Microenvironment-dependent growth of preneoplastic and malignant plasma cells in humanized mice.
Volume: 22
Issue: 11
Pages: 1351-1357
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Publication
24633240 | J:207289
First Author: Rongvaux A
Year: 2014
Journal: Nat Biotechnol
Title: Development and function of human innate immune cells in a humanized mouse model.
Volume: 32
Issue: 4
Pages: 364-72
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Publication
27581357 | J:237212
First Author: Ellegast JM
Year: 2016
Journal: Blood
Title: inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice.
Volume: 128
Issue: 17
Pages: 2130-2134
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Publication
- | J:311907
     
First Author: Sefik E
Year: 2021
Journal: bioRxiv
Title: Viral replication in human macrophages enhances an inflammatory cascade and interferon driven chronic COVID-19 in humanized mice,
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Publication
37957324 | J:350466
First Author: Evans KT
Year: 2023
Journal: Nat Cell Biol
Title: Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis.
Volume: 25
Issue: 12
Pages: 1848-1859
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Publication
8799165 | J:35594
First Author: Kieran MW
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.
Volume: 93
Issue: 17
Pages: 9126-31
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Publication
31515941 | J:286003
First Author: Hashwah H
Year: 2019
Journal: EMBO Mol Med
Title: The IL-6 signaling complex is a critical driver, negative prognostic factor, and therapeutic target in diffuse large B-cell lymphoma.
Volume: 11
Issue: 10
Pages: e10576
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Publication
39813317 | J:361219
First Author: Brandao W
Year: 2025
Journal: Sci Transl Med
Title: Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy.
Volume: 17
Issue: 781
Pages: eadk3690
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Publication
36630911 | J:337514
First Author: Giannou AD
Year: 2023
Journal: Immunity
Title: Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22.
Volume: 56
Issue: 1
Pages: 125-142.e12
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Publication
37550517 | J:340839
First Author: Grockowiak E
Year: 2023
Journal: Nat Cancer
Title: Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms.
Volume: 4
Issue: 8
Pages: 1193-1209
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Publication
37870318 | J:358168
First Author: Wang Y
Year: 2023
Journal: EMBO Rep
Title: Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL-1R/TLR signals.
Volume: 24
Issue: 12
Pages: e57485
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Publication
31582725 | J:282733
First Author: Gerlini R
Year: 2019
Journal: Cell Death Dis
Title: Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice.
Volume: 10
Issue: 10
Pages: 747
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Publication
10943842 | J:63425
First Author: Tamura K
Year: 2000
Journal: Cell
Title: Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis.
Volume: 102
Issue: 2
Pages: 221-31
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Publication
21664343 | J:174962
First Author: Sugiyama D
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Hepatoblasts comprise a niche for fetal liver erythropoiesis through cytokine production.
Volume: 410
Issue: 2
Pages: 301-6
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Publication
10963672 | J:64380
First Author: Puech A
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region.
Volume: 97
Issue: 18
Pages: 10090-5
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Publication
9405660 | J:45079
First Author: Puech A
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Comparative mapping of the human 22q11 chromosomal region and the orthologous region in mice reveals complex changes in gene organization.
Volume: 94
Issue: 26
Pages: 14608-13
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Publication
10337614 | J:54501
First Author: Lund J
Year: 1999
Journal: Mamm Genome
Title: Sequence-ready physical map of the mouse chromosome 16 region with conserved synteny to the human velocardiofacial syndrome region on 22q11.2.
Volume: 10
Issue: 5
Pages: 438-43
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Publication
25773539 | J:236440
First Author: You L
Year: 2015
Journal: J Biol Chem
Title: The chromatin regulator Brpf1 regulates embryo development and cell proliferation.
Volume: 290
Issue: 18
Pages: 11349-64
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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GO Term
GO:0038163 | thrombopoietin-mediated signaling pathway
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Allele
Thpo<em1Smoc> | MGI:7292778
Name: thrombopoietin; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Thpo<tm1(THPO)Smoc> | MGI:7292779
Name: thrombopoietin; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6429663 | C57BL/6JSmoc-Thpo<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6429664 | C57BL/6JSmoc-Thpo<tm1(THPO)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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DO Term
DOID:0061002 | congenital amegakaryocytic thrombocytopenia 2
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Strain
MGI:7751772 | STOCK Prkdc<scid> Il2rg<em1Smoc> Thpo<tm1(THPO)Smoc>/Smoc
Attribute String: endonuclease-mediated mutation, mutant stock, spontaneous mutation, targeted mutation
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Publication
25468569 | J:261836
First Author: Xiao N
Year: 2015
Journal: Blood
Title: Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl.
Volume: 125
Issue: 6
Pages: 941-8
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Publication
21263445 | J:171008
First Author: Landrette SF
Year: 2011
Journal: Leukemia
Title: The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells.
Volume: 25
Issue: 4
Pages: 655-62
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Publication
38792002 | J:349371
 
First Author: Vosbeck K
Year: 2024
Journal: Cancers (Basel)
Title: Neuropilin2 in Mesenchymal Stromal Cells as a Potential Novel Therapeutic Target in Myelofibrosis.
Volume: 16
Issue: 10
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Publication
26878174 | J:232420
First Author: Zhang B
Year: 2016
Journal: J Clin Invest
Title: Heterogeneity of leukemia-initiating capacity of chronic myelogenous leukemia stem cells.
Volume: 126
Issue: 3
Pages: 975-91
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Publication
28034873 | J:238990
First Author: Favale F
Year: 2016
Journal: Blood
Title: An incomplete trafficking defect to the cell-surface leads to paradoxical thrombocytosis for human and murine MPL P106L.
Volume: 128
Issue: 26
Pages: 3146-3158
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Publication
32417303 | J:297135
 
First Author: Rommel MGE
Year: 2020
Journal: Exp Hematol
Title: Signaling properties of murine MPL and MPL mutants after stimulation with thrombopoietin and romiplostim.
Volume: 85
Pages: 33-46.e6
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Publication
27799160 | J:238923
First Author: Iwamura C
Year: 2017
Journal: Blood
Title: Sensing of the microbiota by NOD1 in mesenchymal stromal cells regulates murine hematopoiesis.
Volume: 129
Issue: 2
Pages: 171-176
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Publication
29514790 | J:274109
First Author: Xiao P
Year: 2018
Journal: Blood Adv
Title: Sipa1 deficiency-induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm.
Volume: 2
Issue: 5
Pages: 534-548
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Publication
26552707 | J:229021
First Author: Nakamura-Ishizu A
Year: 2015
Journal: J Exp Med
Title: CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow.
Volume: 212
Issue: 12
Pages: 2133-46
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Publication
10480362 | J:57492
First Author: Smith M
Year: 1999
Journal: Hum Genet
Title: Genomic organisation of the human chordin gene and mutation screening of candidate Cornelia de Lange syndrome genes.
Volume: 105
Issue: 1-2
Pages: 104-11
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Publication
26147434 | J:238394
First Author: Kohlscheen S
Year: 2015
Journal: PLoS One
Title: Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance.
Volume: 10
Issue: 7
Pages: e0131866
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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