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Search results 601 to 700 out of 2570 for Kras

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Category: Publication
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Type Details Score
Publication
36098964 | J:330908
First Author: Zhu LY
Year: 2022
Journal: Cancer Res
Title: Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis.
Volume: 82
Issue: 22
Pages: 4153-4163
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Publication
17114584 | J:116130
First Author: Bardeesy N
Year: 2006
Journal: Genes Dev
Title: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Volume: 20
Issue: 22
Pages: 3130-46
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Publication
21502497 | J:172048
First Author: Lapouge G
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Identifying the cellular origin of squamous skin tumors.
Volume: 108
Issue: 18
Pages: 7431-6
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Publication
27032419 | J:231905
First Author: Hendley AM
Year: 2016
Journal: Cancer Res
Title: p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia.
Volume: 76
Issue: 11
Pages: 3351-63
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Publication
22214849 | J:184382
First Author: Kinross KM
Year: 2012
Journal: J Clin Invest
Title: An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice.
Volume: 122
Issue: 2
Pages: 553-7
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Publication
28622298 | J:261205
First Author: Cammareri P
Year: 2017
Journal: Cell Death Differ
Title: TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis.
Volume: 24
Issue: 10
Pages: 1681-1693
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Publication
21490395 | J:173950
First Author: Pacheco-Pinedo EC
Year: 2011
Journal: J Clin Invest
Title: Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.
Volume: 121
Issue: 5
Pages: 1935-45
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Publication
28439013 | J:242222
First Author: Nakagawa H
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands.
Volume: 114
Issue: 19
Pages: E3806-E3815
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Publication
21684285 | J:275200
First Author: Heid I
Year: 2011
Journal: Gastroenterology
Title: Early requirement of Rac1 in a mouse model of pancreatic cancer.
Volume: 141
Issue: 2
Pages: 719-30, 730.e1-7
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Publication
32312912 | J:308467
 
First Author: Gualandi M
Year: 2020
Journal: Life Sci Alliance
Title: Oncogenic ALK F1174L drives tumorigenesis in cutaneous squamous cell carcinoma.
Volume: 3
Issue: 6
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Publication
24305049 | J:207920
First Author: Rosenfeldt MT
Year: 2013
Journal: Nature
Title: p53 status determines the role of autophagy in pancreatic tumour development.
Volume: 504
Issue: 7479
Pages: 296-300
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Publication
32900774 | J:299186
First Author: Park J
Year: 2020
Journal: Cancer Res
Title: YAP and AP-1 Cooperate to Initiate Pancreatic Cancer Development from Ductal Cells in Mice.
Volume: 80
Issue: 21
Pages: 4768-4779
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Publication
25503558 | J:217739
First Author: Van Mater D
Year: 2015
Journal: Cancer Res
Title: Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway.
Volume: 75
Issue: 3
Pages: 605-14
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Publication
29610318 | J:261816
First Author: Xu H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis.
Volume: 115
Issue: 16
Pages: 4228-4233
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Publication
24803537 | J:260283
First Author: Zhang W
Year: 2014
Journal: Sci Signal
Title: Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma.
Volume: 7
Issue: 324
Pages: ra42
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Publication
26964623 | J:231772
First Author: Ren YA
Year: 2016
Journal: Cancer Res
Title: Mutant p53 Promotes Epithelial Ovarian Cancer by Regulating Tumor Differentiation, Metastasis, and Responsiveness to Steroid Hormones.
Volume: 76
Issue: 8
Pages: 2206-18
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Publication
28475592 | J:247139
First Author: Ma L
Year: 2017
Journal: PLoS One
Title: LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer.
Volume: 12
Issue: 5
Pages: e0176844
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Publication
22628411 | J:193065
First Author: Collisson EA
Year: 2012
Journal: Cancer Discov
Title: A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.
Volume: 2
Issue: 8
Pages: 685-93
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Publication
22056382 | J:184026
First Author: Maniati E
Year: 2011
Journal: J Clin Invest
Title: Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice.
Volume: 121
Issue: 12
Pages: 4685-99
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Publication
31557131 | J:285253
 
First Author: Tu B
Year: 2019
Journal: JCI Insight
Title: YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma.
Volume: 4
Issue: 21
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Publication
26575024 | J:280480
First Author: Mace TA
Year: 2015
Journal: Oncotarget
Title: Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.
Volume: 6
Issue: 42
Pages: 44509-22
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Publication
24694735 | J:213422
First Author: Baumgart S
Year: 2014
Journal: Cancer Discov
Title: Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.
Volume: 4
Issue: 6
Pages: 688-701
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Publication
9659582 | J:52236
First Author: Malkinson AM
Year: 1998
Journal: Exp Lung Res
Title: Molecular comparison of human and mouse pulmonary adenocarcinomas.
Volume: 24
Issue: 4
Pages: 541-55
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28368414 | J:243603
First Author: Principe DR
Year: 2017
Journal: Oncogene
Title: TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function.
Volume: 36
Issue: 30
Pages: 4336-4348
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31148594 | J:310363
First Author: Tang J
Year: 2019
Journal: Lab Invest
Title: Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis.
Volume: 99
Issue: 10
Pages: 1454-1469
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Publication
21471965 | J:171810
First Author: Winslow MM
Year: 2011
Journal: Nature
Title: Suppression of lung adenocarcinoma progression by Nkx2-1.
Volume: 473
Issue: 7345
Pages: 101-4
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Publication
22425996 | J:182575
First Author: Chen Z
Year: 2012
Journal: Nature
Title: A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.
Volume: 483
Issue: 7391
Pages: 613-7
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Publication
22945650 | J:203248
First Author: To MD
Year: 2013
Journal: Oncogene
Title: Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.
Volume: 32
Issue: 34
Pages: 4028-33
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Publication
31526907 | J:302690
First Author: Kaneta Y
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: Loss of Pancreatic E-Cadherin Causes Pancreatitis-Like Changes and Contributes to Carcinogenesis.
Volume: 9
Issue: 1
Pages: 105-119
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Publication
16397221 | J:105031
First Author: Hruban RH
Year: 2006
Journal: Cancer Res
Title: Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.
Volume: 66
Issue: 1
Pages: 95-106
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Publication
33753374 | J:305534
First Author: Ancey PB
Year: 2021
Journal: Cancer Res
Title: GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy.
Volume: 81
Issue: 9
Pages: 2345-2357
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Publication
38733583 | J:349756
First Author: Shrestha H
Year: 2024
Journal: Cell Rep
Title: The Janus kinase 1 is critical for pancreatic cancer initiation and progression.
Volume: 43
Issue: 5
Pages: 114202
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25713296 | J:221201
First Author: Lahtela J
Year: 2015
Journal: Dis Model Mech
Title: The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis.
Volume: 8
Issue: 4
Pages: 393-401
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35904492 | J:330081
First Author: Chen S
Year: 2022
Journal: Cancer Discov
Title: Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Volume: 12
Issue: 10
Pages: 2434-2453
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22421440 | J:183391
First Author: Mann KM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.
Volume: 109
Issue: 16
Pages: 5934-41
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Publication
37842094 | J:341659
 
First Author: Fernandes LM
Year: 2023
Journal: Front Cell Dev Biol
Title: Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function.
Volume: 11
Pages: 1276333
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Publication
25683115 | J:309413
First Author: Chalabi-Dchar M
Year: 2015
Journal: Gastroenterology
Title: Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
Volume: 148
Issue: 7
Pages: 1452-65
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Publication
32446697 | J:314306
First Author: Armacki M
Year: 2020
Journal: Gastroenterology
Title: Protein Kinase D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From Cancer Cells That Promote Metastasis to Lung in Mice.
Volume: 159
Issue: 3
Pages: 1019-1035.e22
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Publication
29248441 | J:309349
First Author: He P
Year: 2018
Journal: Gastroenterology
Title: Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.
Volume: 154
Issue: 5
Pages: 1494-1508.e13
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Publication
22975375 | J:192907
First Author: Navas C
Year: 2012
Journal: Cancer Cell
Title: EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma.
Volume: 22
Issue: 3
Pages: 318-30
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Publication
36596776 | J:332388
First Author: Han L
Year: 2023
Journal: Nat Commun
Title: The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
Volume: 14
Issue: 1
Pages: 1
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27872088 | J:239406
First Author: Drosten M
Year: 2017
Journal: Cancer Res
Title: H-Ras and K-Ras Oncoproteins Induce Different Tumor Spectra When Driven by the Same Regulatory Sequences.
Volume: 77
Issue: 3
Pages: 707-718
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Publication
32241947 | J:286610
First Author: Badgley MA
Year: 2020
Journal: Science
Title: Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Volume: 368
Issue: 6486
Pages: 85-89
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Publication
29282223 | J:261891
First Author: Sakai E
Year: 2018
Journal: Cancer Res
Title: Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer.
Volume: 78
Issue: 5
Pages: 1334-1346
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Publication
27215660 | J:236047
First Author: Gruber R
Year: 2016
Journal: Gastroenterology
Title: YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.
Volume: 151
Issue: 3
Pages: 526-39
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Publication
29604291 | J:273105
First Author: Kimura Y
Year: 2018
Journal: Gastroenterology
Title: ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.
Volume: 155
Issue: 1
Pages: 194-209.e2
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Publication
21423204 | J:174632
First Author: Mullany LK
Year: 2011
Journal: Oncogene
Title: Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.
Volume: 30
Issue: 32
Pages: 3522-36
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Publication
24737887 | J:208835
First Author: Schmit F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PI3K isoform dependence of PTEN-deficient tumors can be altered by the genetic context.
Volume: 111
Issue: 17
Pages: 6395-400
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24717934 | J:310016
First Author: Morran DC
Year: 2014
Journal: Gut
Title: Targeting mTOR dependency in pancreatic cancer.
Volume: 63
Issue: 9
Pages: 1481-9
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Publication
25311989 | J:225421
First Author: Wu CY
Year: 2014
Journal: Gastroenterology
Title: PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
Volume: 147
Issue: 6
Pages: 1405-16.e7
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Publication
25133424 | J:215828
First Author: Chamberlain CE
Year: 2014
Journal: J Clin Invest
Title: Menin determines K-RAS proliferative outputs in endocrine cells.
Volume: 124
Issue: 9
Pages: 4093-101
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Publication
30887098 | J:290284
First Author: Shrestha A
Year: 2019
Journal: Cell Mol Life Sci
Title: A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development.
Volume: 76
Issue: 14
Pages: 2817-2832
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Publication
26438693 | J:226535
First Author: Ocal O
Year: 2015
Journal: Dis Model Mech
Title: A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.
Volume: 8
Issue: 10
Pages: 1201-11
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30296435 | J:309357
First Author: Görgülü K
Year: 2019
Journal: Gastroenterology
Title: Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice.
Volume: 156
Issue: 1
Pages: 203-217.e20
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Publication
21965329 | J:178461
First Author: Pearson HB
Year: 2011
Journal: J Clin Invest
Title: SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.
Volume: 121
Issue: 11
Pages: 4257-67
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Publication
24753163 | J:214343
First Author: Cai Z
Year: 2014
Journal: Dev Dyn
Title: Role of heparan sulfate proteoglycans in optic disc and stalk morphogenesis.
Volume: 243
Issue: 10
Pages: 1310-6
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24284065 | J:310318
First Author: Li H
Year: 2014
Journal: J Cell Sci
Title: Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development.
Volume: 127
Issue: Pt 3
Pages: 571-82
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28489818 | J:252525
First Author: Tammela T
Year: 2017
Journal: Nature
Title: A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.
Volume: 545
Issue: 7654
Pages: 355-359
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22464334 | J:243760
First Author: Farago AF
Year: 2012
Journal: Cell
Title: SnapShot: Lung cancer models.
Volume: 149
Issue: 1
Pages: 246-246.e1
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26119937 | J:234215
First Author: Hessmann E
Year: 2016
Journal: Oncogene
Title: MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies.
Volume: 35
Issue: 13
Pages: 1609-18
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24058167 | J:202949
First Author: Chang DR
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Lung epithelial branching program antagonizes alveolar differentiation.
Volume: 110
Issue: 45
Pages: 18042-51
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24366883 | J:208170
First Author: James MA
Year: 2014
Journal: Cancer Res
Title: CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis.
Volume: 74
Issue: 4
Pages: 1116-27
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11528387 | J:71546
First Author: Zhang Z
Year: 2001
Journal: Nat Genet
Title: Wildtype Kras2 can inhibit lung carcinogenesis in mice.
Volume: 29
Issue: 1
Pages: 25-33
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16247446 | J:107330
First Author: Wang Y
Year: 2006
Journal: Oncogene
Title: Prevention of lung cancer progression by bexarotene in mouse models.
Volume: 25
Issue: 9
Pages: 1320-9
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24354449 | J:312156
First Author: Luo F
Year: 2014
Journal: Int J Exp Pathol
Title: Wild-type K-ras has a tumour suppressor effect on carcinogen-induced murine colorectal adenoma formation.
Volume: 95
Issue: 1
Pages: 8-15
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11360188 | J:69250
First Author: Liu ML
Year: 2001
Journal: Oncogene
Title: Haploid loss of Ki-ras delays mammary tumor progression in C3 (1)/SV40 Tag transgenic mice.
Volume: 20
Issue: 16
Pages: 2044-9
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16247444 | J:107333
First Author: Wang Y
Year: 2006
Journal: Oncogene
Title: A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
Volume: 25
Issue: 8
Pages: 1277-80
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18062963 | J:133431
First Author: Patek CE
Year: 2008
Journal: Exp Cell Res
Title: Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.
Volume: 314
Issue: 5
Pages: 1105-14
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9294608 | J:42943
First Author: Koera K
Year: 1997
Journal: Oncogene
Title: K-ras is essential for the development of the mouse embryo.
Volume: 15
Issue: 10
Pages: 1151-9
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16720837 | J:115071
First Author: Braun BS
Year: 2006
Journal: Blood
Title: Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo.
Volume: 108
Issue: 6
Pages: 2041-4
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20832755 | J:164198
First Author: Hatley ME
Year: 2010
Journal: Cancer Cell
Title: Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21.
Volume: 18
Issue: 3
Pages: 282-93
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24525739 | J:210533
First Author: Zhong R
Year: 2014
Journal: Cancer Res
Title: Bioluminescent imaging of HPV-positive oral tumor growth and its response to image-guided radiotherapy.
Volume: 74
Issue: 7
Pages: 2073-81
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22430205 | J:187582
First Author: Zhou C
Year: 2013
Journal: Oncogene
Title: The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis.
Volume: 32
Issue: 7
Pages: 903-9
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15093544 | J:89333
First Author: Tuveson DA
Year: 2004
Journal: Cancer Cell
Title: Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.
Volume: 5
Issue: 4
Pages: 375-87
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Publication
28846072 | J:247853
First Author: Tarnawsky SP
Year: 2017
Journal: J Clin Invest
Title: Mice expressing KrasG12D in hematopoietic multipotent progenitor cells develop neonatal myeloid leukemia.
Volume: 127
Issue: 10
Pages: 3652-3656
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Publication
15289303 | J:91877
First Author: Caulin C
Year: 2004
Journal: Cancer Res
Title: Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity.
Volume: 64
Issue: 15
Pages: 5054-8
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17317860 | J:145429
First Author: Zhang J
Year: 2007
Journal: Blood
Title: Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways.
Volume: 109
Issue: 12
Pages: 5238-41
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29047229 | J:257131
 
First Author: Parikh N
Year: 2018
Journal: Aging Cell
Title: Enhanced inflammation and attenuated tumor suppressor pathways are associated with oncogene-induced lung tumors in aged mice.
Volume: 17
Issue: 1
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21381032 | J:171248
First Author: van der Weyden L
Year: 2011
Journal: J Pathol
Title: Acute sensitivity of the oral mucosa to oncogenic K-ras.
Volume: 224
Issue: 1
Pages: 22-32
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Publication
19435821 | J:205246
First Author: Abel TW
Year: 2009
Journal: Mol Cancer Res
Title: GFAP-Cre-mediated activation of oncogenic K-ras results in expansion of the subventricular zone and infiltrating glioma.
Volume: 7
Issue: 5
Pages: 645-53
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25629724 | J:219792
 
First Author: Schlomann U
Year: 2015
Journal: Nat Commun
Title: ADAM8 as a drug target in pancreatic cancer.
Volume: 6
Pages: 6175
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Publication
18271008 | J:135568
First Author: Calcagno SR
Year: 2008
Journal: Int J Cancer
Title: Oncogenic K-ras promotes early carcinogenesis in the mouse proximal colon.
Volume: 122
Issue: 11
Pages: 2462-70
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22653055 | J:190477
First Author: Sangodkar J
Year: 2012
Journal: J Clin Invest
Title: Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response.
Volume: 122
Issue: 7
Pages: 2637-51
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23168260 | J:196340
First Author: Mallette FA
Year: 2012
Journal: Cell Rep
Title: JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5.
Volume: 2
Issue: 5
Pages: 1233-43
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Publication
27651310 | J:237838
First Author: Jang HJ
Year: 2016
Journal: Cancer Res
Title: Chronic Stress Facilitates Lung Tumorigenesis by Promoting Exocytosis of IGF2 in Lung Epithelial Cells.
Volume: 76
Issue: 22
Pages: 6607-6619
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Publication
16823377 | J:111642
First Author: To MD
Year: 2006
Journal: Nat Genet
Title: A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice.
Volume: 38
Issue: 8
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