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Search results 1 to 1 out of 1 for Cdkn1a

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
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Type Details Score
Protein Domain
IPR029841 | CDKN1A
Type: Family
Description: This entry represents the cyclin-dependent kinase inhibitor 1 (CDKN1A, also known as p21) from animals. It is a direct transcriptional target of p53 and may repress apoptosis []. It mediates several important physiological effects of p53, including DNA-damage-induced cell cycle checkpoints [, ]. p21 plays a critical role in regulating cell growth and the cell response to DNA damage[].
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