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Search results 2801 to 2892 out of 2892 for Cdkn1a

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Hits by Strain

Type Details Score
Protein
P04202
Organism: Mus musculus/domesticus
Length: 390  
Fragment?: false
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Publication
19667129 | J:153844
First Author: Yamakoshi K
Year: 2009
Journal: J Cell Biol
Title: Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.
Volume: 186
Issue: 3
Pages: 393-407
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Allele
Igs2<tm1(Cdkn1a-cre/ERT2,-EGFP)Mxu> | MGI:7469624
Name: intergenic site 2; targeted mutation 1, Ming Xu
Allele Type: Targeted
Attribute String: Inducible, Recombinase, Reporter
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Publication
27668660 | J:259337
First Author: Schmitt AM
Year: 2016
Journal: Nat Genet
Title: An inducible long noncoding RNA amplifies DNA damage signaling.
Volume: 48
Issue: 11
Pages: 1370-1376
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Publication
22307631 | J:182031
First Author: Goh AM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Using targeted transgenic reporter mice to study promoter-specific p53 transcriptional activity.
Volume: 109
Issue: 5
Pages: 1685-90
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Genotype
Genotype
Symbol: Tg(Atoh1-sb11)1Mtay/? TgTn(sb-T2/Onc3)12740Njen/?
Background: involves: C3H * C57BL/6J * ICR
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
E-GEOD-31643 | Conditional ablation of the Notch2 receptor in the ocular lens
Series Id: GSE31643
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-70208 | GRP78 regulates ER homeostasis and distal epithelial cell survival during lung development
Series Id: GSE70208
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
23803760 | J:204711
First Author: Yoshimoto S
Year: 2013
Journal: Nature
Title: Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome.
Volume: 499
Issue: 7456
Pages: 97-101
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Publication
35681513 | J:325568
 
First Author: Marney CB
Year: 2022
Journal: Cells
Title: A Unique Spectrum of Spontaneous Tumors in Dino Knockout Mice Identifies Tissue-Specific Requirements for Tumor Suppression.
Volume: 11
Issue: 11
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Publication
25526089 | J:260364
First Author: Li L
Year: 2015
Journal: Cell Death Differ
Title: A unique role for p53 in the regulation of M2 macrophage polarization.
Volume: 22
Issue: 7
Pages: 1081-93
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Publication
26760213 | J:241192
First Author: Morrissy AS
Year: 2016
Journal: Nature
Title: Divergent clonal selection dominates medulloblastoma at recurrence.
Volume: 529
Issue: 7586
Pages: 351-7
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Publication
39111286 | J:353286
First Author: Wang B
Year: 2024
Journal: Cell Metab
Title: Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function.
Volume: 36
Issue: 8
Pages: 1795-1805.e6
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Genotype
Genotype
Symbol: Tg(Atoh1-sb11)1Mtay/? TgTn(sb-T2/Onc3)12740Njen/? Trp53/Trp53
Background: involves: 129S2/SvPas * C3H * C57BL/6J * ICR
Zygosity: cn
Has Mutant Allele: true
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Protein Coding Gene
MGI:98834 | Trp53
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P02340
Organism: Mus musculus/domesticus
Length: 390  
Fragment?: false
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Publication
25959802 | J:303198
First Author: Tanaka T
Year: 2015
Journal: J Reprod Dev
Title: The CDKN1B-RB1-E2F1 pathway protects mouse spermatogonial stem cells from genomic damage.
Volume: 61
Issue: 4
Pages: 305-16
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Publication
25774828 | J:221881
 
First Author: Wang S
Year: 2015
Journal: Nat Commun
Title: Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.
Volume: 6
Pages: 6517
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Publication
29928692 | J:288129
First Author: Kaneko S
Year: 2018
Journal: Sci Adv
Title: X chromosome protects against bladder cancer in females via a KDM6A-dependent epigenetic mechanism.
Volume: 4
Issue: 6
Pages: eaar5598
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Publication
16951689 | J:112660
First Author: Kirstetter P
Year: 2006
Journal: Nat Immunol
Title: Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.
Volume: 7
Issue: 10
Pages: 1048-56
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Publication
26136427 | J:271921
First Author: Iguchi T
Year: 2015
Journal: J Immunol
Title: BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells.
Volume: 195
Issue: 3
Pages: 982-93
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Publication
20708584 | J:163670
First Author: Spruce T
Year: 2010
Journal: Dev Cell
Title: An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo.
Volume: 19
Issue: 2
Pages: 207-19
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Publication
24813889 | J:210596
First Author: Pollock A
Year: 2014
Journal: Cell Rep
Title: Growth of the developing cerebral cortex is controlled by microRNA-7 through the p53 pathway.
Volume: 7
Issue: 4
Pages: 1184-96
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Publication
28495880 | J:249491
First Author: Xu EE
Year: 2017
Journal: Diabetes
Title: SOX4 Allows Facultative β-Cell Proliferation Through Repression of Cdkn1a.
Volume: 66
Issue: 8
Pages: 2213-2219
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Publication
30257220 | J:349193
First Author: Avey D
Year: 2018
Journal: Cell Rep
Title: Single-Cell RNA-Seq Uncovers a Robust Transcriptional Response to Morphine by Glia.
Volume: 24
Issue: 13
Pages: 3619-3629.e4
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Publication
33035772 | J:303508
 
First Author: Zhang L
Year: 2020
Journal: Cell Immunol
Title: PHF14 is required for germinal center B cell development.
Volume: 358
Pages: 104221
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Publication
22343890 | J:181542
First Author: Wu X
Year: 2012
Journal: Nature
Title: Clonal selection drives genetic divergence of metastatic medulloblastoma.
Volume: 482
Issue: 7386
Pages: 529-33
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Publication
25391241 | J:219650
First Author: Faria CC
Year: 2015
Journal: Cancer Res
Title: Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
Volume: 75
Issue: 1
Pages: 134-46
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Publication
24911145 | J:213794
First Author: Zhu Y
Year: 2014
Journal: J Clin Invest
Title: Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging.
Volume: 124
Issue: 7
Pages: 3263-73
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Publication
37353538 | J:338133
First Author: Matsudaira T
Year: 2023
Journal: Commun Biol
Title: Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype.
Volume: 6
Issue: 1
Pages: 665
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Genotype
Genotype
Symbol: Ptch1/Ptch1<+> Tg(Atoh1-sb11)1Mtay/? TgTn(sb-T2/Onc3)12740Njen/?
Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6J * ICR
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Igs2/Igs2<+>
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Igs2/Igs2<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Publication
20190815 | J:186051
First Author: Liu Q
Year: 2010
Journal: Oncogene
Title: A role of Miz-1 in Gfi-1-mediated transcriptional repression of CDKN1A.
Volume: 29
Issue: 19
Pages: 2843-52
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Publication
31138526 | J:277546
First Author: Xue Y
Year: 2019
Journal: Cancer Res
Title: Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo.
Volume: 79
Issue: 14
Pages: 3595-3607
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Publication
16169021 | J:106402
First Author: di Masi A
Year: 2006
Journal: Mutat Res
Title: Gene expression and apoptosis induction in p53-heterozygous irradiated mice.
Volume: 594
Issue: 1-2
Pages: 49-62
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Publication
19850742 | J:156838
First Author: Lacombe J
Year: 2010
Journal: Blood
Title: Scl regulates the quiescence and the long-term competence of hematopoietic stem cells.
Volume: 115
Issue: 4
Pages: 792-803
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Publication
20308320 | J:162589
First Author: Hoi CS
Year: 2010
Journal: Mol Cell Biol
Title: Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin.
Volume: 30
Issue: 10
Pages: 2518-36
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Publication
37348155 | J:337247
 
First Author: Grimm SL
Year: 2023
Journal: Redox Biol
Title: Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation.
Volume: 64
Pages: 102790
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Publication
20876806 | J:164646
First Author: Gruber TA
Year: 2010
Journal: Cancer Res
Title: Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia.
Volume: 70
Issue: 19
Pages: 7411-20
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Publication
24586582 | J:213763
First Author: Sanz-Moreno A
Year: 2014
Journal: PLoS One
Title: Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation.
Volume: 9
Issue: 2
Pages: e89187
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Publication
26699484 | J:228497
First Author: Gu Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: The histone H2A deubiquitinase Usp16 regulates hematopoiesis and hematopoietic stem cell function.
Volume: 113
Issue: 1
Pages: E51-60
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Publication
22039255 | J:179063
First Author: Kobayashi M
Year: 2011
Journal: Blood
Title: Regulation of murine hematopoietic stem cell quiescence by Dmtf1.
Volume: 118
Issue: 25
Pages: 6562-71
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Publication
24789767 | J:212932
First Author: Zhang Y
Year: 2014
Journal: J Pathol
Title: Tissue-specific and age-dependent effects of global Mdm2 loss.
Volume: 233
Issue: 4
Pages: 380-91
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Publication
28991228 | J:257886
First Author: Lee S
Year: 2018
Journal: Oncogene
Title: Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma.
Volume: 37
Issue: 5
Pages: 616-626
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Publication
20667977 | J:191182
First Author: Hewitt SC
Year: 2010
Journal: FASEB J
Title: Biological and biochemical consequences of global deletion of exon 3 from the ER alpha gene.
Volume: 24
Issue: 12
Pages: 4660-7
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Publication
31331961 | J:278688
 
First Author: Jezek J
Year: 2019
Journal: J Cell Sci
Title: Synergistic repression of thyroid hyperplasia by cyclin C and Pten.
Volume: 132
Issue: 16
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Publication
28754837 | J:247940
First Author: Bosnakovski D
Year: 2017
Journal: Dis Model Mech
Title: p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy.
Volume: 10
Issue: 10
Pages: 1211-1216
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Publication
35170357 | J:322937
First Author: Auyeung VC
Year: 2022
Journal: Am J Physiol Lung Cell Mol Physiol
Title: IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis.
Volume: 322
Issue: 4
Pages: L564-L580
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Publication
31915197 | J:285817
First Author: Mondello P
Year: 2020
Journal: Cancer Discov
Title: Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma.
Volume: 10
Issue: 3
Pages: 440-459
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Publication
22936656 | J:191803
First Author: Schuettpelz LG
Year: 2012
Journal: Blood
Title: Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function.
Volume: 120
Issue: 15
Pages: 2981-9
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Publication
33631277 | J:316394
 
First Author: Doty RT
Year: 2021
Journal: Exp Hematol
Title: Single-cell analysis of erythropoiesis in Rpl11 haploinsufficient mice reveals insight into the pathogenesis of Diamond-Blackfan anemia.
Volume: 97
Pages: 66-78.e6
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Publication
25238756 | J:233368
First Author: Li J
Year: 2014
Journal: J Immunol
Title: Requirement for ssbp2 in hematopoietic stem cell maintenance and stress response.
Volume: 193
Issue: 9
Pages: 4654-62
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Publication
30876690 | J:290306
First Author: Chen X
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice.
Volume: 512
Issue: 1
Pages: 119-124
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Publication
22253232 | J:181490
First Author: Jeon BN
Year: 2012
Journal: Cancer Res
Title: KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A.
Volume: 72
Issue: 5
Pages: 1137-48
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Publication
28334846 | J:242244
First Author: Ma X
Year: 2017
Journal: Hum Mol Genet
Title: DAPL1, a susceptibility locus for age-related macular degeneration, acts as a novel suppressor of cell proliferation in the retinal pigment epithelium.
Volume: 26
Issue: 9
Pages: 1612-1621
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Publication
33268499 | J:299741
First Author: Gudmundsson KO
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence.
Volume: 117
Issue: 50
Pages: 31945-31953
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Publication
32779886 | J:296379
   
First Author: Yang D
Year: 2020
Journal: Aging Cell
Title: Histone methyltransferase Smyd3 is a new regulator for vascular senescence.
Pages: e13212
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Publication
9370275 | J:43288
First Author: Okuda M
Year: 1997
Journal: Gene
Title: Cloning and chromosome mapping of the feline genes p21WAF1 and p27Kip1.
Volume: 198
Issue: 1-2
Pages: 141-7
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Publication
10453093 | J:57338
First Author: Ostapenko VV
Year: 1999
Journal: Radiat Res
Title: Increased resistance of the radiosensitive M10 mutant cells of the L5178Y mouse lymphoma cell line to heat-induced apoptosis.
Volume: 152
Issue: 3
Pages: 321-7
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Publication
23438076 | J:198148
First Author: Yin Y
Year: 2013
Journal: Biochem J
Title: Nuclear export factor 3 is involved in regulating the expression of TGF-β3 in an mRNA export activity-independent manner in mouse Sertoli cells.
Volume: 452
Issue: 1
Pages: 67-78
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Publication
24713392 | J:210962
First Author: Wan J
Year: 2014
Journal: Am J Pathol
Title: M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease.
Volume: 184
Issue: 6
Pages: 1763-72
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Publication
26574435 | J:237668
First Author: Shizu R
Year: 2016
Journal: Biochem J
Title: PXR stimulates growth factor-mediated hepatocyte proliferation by cross-talk with the FOXO transcription factor.
Volume: 473
Issue: 3
Pages: 257-66
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Publication
20824133 | J:356941
 
First Author: Patel VN
Year: 2010
Journal: PLoS One
Title: Prediction and testing of biological networks underlying intestinal cancer.
Volume: 5
Issue: 9
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Publication
33770102 | J:304863
First Author: Lemarié M
Year: 2021
Journal: PLoS Genet
Title: IKAROS is required for the measured response of NOTCH target genes upon external NOTCH signaling.
Volume: 17
Issue: 3
Pages: e1009478
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Publication
18285661 | J:347124
First Author: Sugihara T
Year: 2008
Journal: J Radiat Res
Title: Inverse dose-rate-effects on the expressions of extra-cellular matrix-related genes in low-dose-rate gamma-ray irradiated murine cells.
Volume: 49
Issue: 3
Pages: 231-40
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Publication
23840792 | J:204327
First Author: Fozzatti L
Year: 2013
Journal: PLoS One
Title: Oncogenic Actions of the Nuclear Receptor Corepressor (NCOR1) in a Mouse Model of Thyroid Cancer.
Volume: 8
Issue: 6
Pages: e67954
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Publication
27696085 | J:288155
First Author: Ashton KJ
Year: 2017
Journal: Purinergic Signal
Title: Transcriptomic effects of adenosine 2A receptor deletion in healthy and endotoxemic murine myocardium.
Volume: 13
Issue: 1
Pages: 27-49
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Publication
26447190 | J:230670
First Author: Matthews GM
Year: 2015
Journal: Blood
Title: Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Volume: 126
Issue: 21
Pages: 2392-403
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Publication
24465590 | J:212339
First Author: Millán-Uclés A
Year: 2014
Journal: PLoS One
Title: A conditional mouse mutant in the tumor suppressor SdhD gene unveils a link between p21(WAF1/Cip1) induction and mitochondrial dysfunction.
Volume: 9
Issue: 1
Pages: e85528
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Publication
37036079 | J:335209
First Author: Ng WH
Year: 2023
Journal: mBio
Title: Role of MXRA8 in Ross River Virus Disease Pathogenesis.
Volume: 14
Issue: 2
Pages: e0058823
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Publication
24336083 | J:320704
 
First Author: Valentino T
Year: 2013
Journal: Cell Death Dis
Title: PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context.
Volume: 4
Pages: e963
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Publication
35741845 | J:333336
 
First Author: Feng M
Year: 2022
Journal: Genes (Basel)
Title: Tubulin TUBB4B Is Involved in Spermatogonia Proliferation and Cell Cycle Processes.
Volume: 13
Issue: 6
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Publication
29474906 | J:257438
First Author: Garzia L
Year: 2018
Journal: Cell
Title: A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.
Volume: 172
Issue: 5
Pages: 1050-1062.e14
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Publication
35024619 | J:335288
First Author: Wang B
Year: 2021
Journal: Nat Aging
Title: An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo.
Volume: 1
Issue: 10
Pages: 962-973
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Publication
34813734 | J:321716
First Author: Wang L
Year: 2022
Journal: Cell Metab
Title: Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity.
Volume: 34
Issue: 1
Pages: 75-89.e8
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Publication
31154022 | J:289338
First Author: Luo Y
Year: 2019
Journal: Gastroenterology
Title: Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6.
Volume: 157
Issue: 3
Pages: 744-759.e4
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Publication
19351403 | J:148507
 
First Author: Llamas B
Year: 2009
Journal: BMC Genomics
Title: Chromosome Y variants from different inbred mouse strains are linked to differences in the morphologic and molecular responses of cardiac cells to postpubertal testosterone.
Volume: 10
Pages: 150
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Publication
32727874 | J:299853
 
First Author: Kutle I
Year: 2020
Journal: J Virol
Title: Murine Cytomegalovirus M25 Proteins Sequester the Tumor Suppressor Protein p53 in Nuclear Accumulations.
Volume: 94
Issue: 20
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Publication
16110338 | J:107820
First Author: Corbo JC
Year: 2005
Journal: PLoS Genet
Title: A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.
Volume: 1
Issue: 2
Pages: e11
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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