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Search results 101 to 135 out of 135 for Tpt1

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Type Details Score
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
31019096 | -
First Author: Munir A
Year: 2019
Journal: RNA
Title: NAD+-dependent RNA terminal 2' and 3' phosphomonoesterase activity of a subset of Tpt1 enzymes.
Volume: 25
Issue: 7
Pages: 783-792
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GO Term
GO:0000215 | tRNA 2'-phosphotransferase activity
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Publication
9915792 | -
First Author: Spinelli SL
Year: 1999
Journal: J Biol Chem
Title: Transient ADP-ribosylation of a 2'-phosphate implicated in its removal from ligated tRNA during splicing in yeast.
Volume: 274
Issue: 5
Pages: 2637-44
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Publication
11705403 | -
First Author: Steiger MA
Year: 2001
Journal: Biochemistry
Title: Substrate recognition by a yeast 2'-phosphotransferase involved in tRNA splicing and by its Escherichia coli homolog.
Volume: 40
Issue: 46
Pages: 14098-105
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Protein Domain
IPR022928 | RNA_2'-PTrans_KptA
Type: Family
Description: This entry represents KptA, a putative RNA 2'-phosphotransferase. KptA, a functional Tpt1 protein homologue from Escherichia coli is strikingly similar to yeast Tpt1 in its kinetic parameters, although E. coli is not known to have a 2'-phosphorylated RNA substrate [, ].
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Protein Coding Gene
MGI:1333115 | Trpt1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
8392224 | -
First Author: Culver GM
Year: 1993
Journal: Science
Title: An NAD derivative produced during transfer RNA splicing: ADP-ribose 1"-2" cyclic phosphate.
Volume: 261
Issue: 5118
Pages: 206-8
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Publication
30202863 | -
First Author: Munir A
Year: 2018
Journal: Nucleic Acids Res
Title: NAD+-dependent synthesis of a 5'-phospho-ADP-ribosylated RNA/DNA cap by RNA 2'-phosphotransferase Tpt1.
Volume: 46
Issue: 18
Pages: 9617-9624
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Publication
2154680 | -
First Author: McCraith SM
Year: 1990
Journal: Mol Cell Biol
Title: A highly specific phosphatase from Saccharomyces cerevisiae implicated in tRNA splicing.
Volume: 10
Issue: 3
Pages: 1049-55
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Protein Domain
IPR002745 | Ptrans_KptA/Tpt1
Type: Family
Description: This entry includes Tpt1 and its homologues from all domains of life. Tpt1 was first discovered as an essential component of the fungal tRNA splicing pathway, which characteristically generates a 2'-PO4, 3'-5' phosphodiester splice junction during the tRNA ligation reaction []. It is an enzyme that catalyzes the transfer of an internal RNA 2'-monophosphate (2'-PO4) to NAD+ to form a 2'-OH RNA, ADP-ribose 1"-2"cyclic phosphate, and nicotinamide []. Interestingly, many Tpt1 homologues have no obvious need for an RNA 2'-phosphotransferase because: (i) they lack tRNA introns; and/or (ii) they are not known to have an enzymatic pathway that generates 2'-PO4, 3'-5' phosphodiester RNA structures. There are more evidence showing that Tpt1 homologues are not limited to the canonical activity of Tpt1 healing the 2'-PO4, 3'-5' phosphodiester RNA splice junction formed during fungal and plant tRNA splicing []. Instead, the ADP-ribosyl transfer to a phosphorylated substrate is the unifying mechanistic feature of Tpt1-catalyzed reactions. For instance, some Tpt1 homologues have been shown to catalyze the transfer of ADP-ribose from NAD+ to a 5'-monophosphate end of RNA or DNA to install a 5'-phospho-ADP-ribose cap structure [].
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Protein
Q8K3A2
Organism: Mus musculus/domesticus
Length: 249  
Fragment?: false
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