Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Joshi SS |
Year: |
2019 |
Journal: |
PLoS Genet |
Title: |
CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties. |
Volume: |
15 |
Issue: |
4 |
Pages: |
e1008034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suda T |
Year: |
1991 |
Journal: |
Exp Hematol |
Title: |
Molecular cloning and expression of mouse CD34 gene |
Volume: |
19 |
|
Pages: |
465 (Abstr.) |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
325
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
104
|
Fragment?: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; wild type |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Huettner CS |
Year: |
2003 |
Journal: |
Blood |
Title: |
Inducible expression of BCR/ABL using human CD34 regulatory elements results in a megakaryocytic myeloproliferative syndrome. |
Volume: |
102 |
Issue: |
9 |
Pages: |
3363-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ladeby R |
Year: |
2005 |
Journal: |
Glia |
Title: |
Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury. |
Volume: |
50 |
Issue: |
2 |
Pages: |
121-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bockamp EO |
Year: |
1997 |
Journal: |
J Biol Chem |
Title: |
Distinct mechanisms direct SCL/tal-1 expression in erythroid cells and CD34 positive primitive myeloid cells. |
Volume: |
272 |
Issue: |
13 |
Pages: |
8781-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hsieh MJ |
Year: |
2020 |
Journal: |
Int J Mol Sci |
Title: |
Inactivation of APC Induces CD34 Upregulation to Promote Epithelial-Mesenchymal Transition and Cancer Stem Cell Traits in Pancreatic Cancer. |
Volume: |
21 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ragone G |
Year: |
2009 |
Journal: |
Oncogene |
Title: |
The Tcl1 oncogene defines secondary hair germ cells differentiation at catagen-telogen transition and affects stem-cell marker CD34 expression. |
Volume: |
28 |
Issue: |
10 |
Pages: |
1329-38 |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; endonuclease-mediated mutation 1, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; targeted mutation 1, Akira Suzuki |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; endonuclease-mediated mutation 2, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Publication |
First Author: |
Kerr SC |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Endoglycan, a member of the CD34 family of sialomucins, is a ligand for the vascular selectins. |
Volume: |
181 |
Issue: |
2 |
Pages: |
1480-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Besson V |
Year: |
2017 |
Journal: |
Stem Cells |
Title: |
Expression Analysis of the Stem Cell Marker Pw1/Peg3 Reveals a CD34 Negative Progenitor Population in the Hair Follicle. |
Volume: |
35 |
Issue: |
4 |
Pages: |
1015-1027 |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; targeted mutation 2e, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; targeted mutation 1e, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; targeted mutation 2a, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; targeted mutation 1a, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Allele |
Name: |
CD34 antigen; targeted mutation 1, Larry A Lasky |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd34/Cd34 |
Background: |
involves: 129P2/OlaHsd * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Fieger CB |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Endoglycan, a member of the CD34 family, functions as an L-selectin ligand through modification with tyrosine sulfation and sialyl Lewis x. |
Volume: |
278 |
Issue: |
30 |
Pages: |
27390-8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466287 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3540217 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7466302 |
Age: |
embryonic day 10.5 |
Image: |
5A CD31 (upper) |
Note: |
Co-expression with Cd34 in cells in other lumens. |
Specimen Label: |
5A CD31 (upper) |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466287 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3819917 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7466302 |
Age: |
embryonic day 10.5 |
Image: |
5B CD31 (upper) |
Note: |
Co-expression with Cd34 emerging from endothelial cell layer of aorta. |
Specimen Label: |
5B CD31 (upper) |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466287 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3540217 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7466302 |
Age: |
embryonic day 10.5 |
Image: |
5B CD31 (upper) |
Note: |
Co-expression with Cd34 in cells in other lumens |
Specimen Label: |
5B CD31 (upper) |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd34/Cd34 |
Background: |
involves: 129S2/SvPas |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumaran GK |
Year: |
2020 |
Journal: |
FEBS J |
Title: |
Identification and classification of epithelial cells in nephron segments by actin cytoskeleton patterns. |
Volume: |
287 |
Issue: |
6 |
Pages: |
1176-1194 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5829446 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-03-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5829453 |
Age: |
embryonic day 10.5 |
|
Note: |
Expressed in the cells that form the vessels, which is also positive for Cd34 and Eng. |
Specimen Label: |
1A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466287 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3819917 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7466302 |
Age: |
embryonic day 10.5 |
Image: |
5A CD31 (upper) |
Note: |
Co-expression with Cd34 in cells emerging from endothelial cell layer of aorta. |
Specimen Label: |
5A CD31 (upper) |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466287 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3540217 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7466302 |
Age: |
embryonic day 10.5 |
Image: |
5C CD31 (upper) |
Note: |
Co-expression with Cd34 in a few cells in other cavities beyond aorta. |
Specimen Label: |
5C CD31 (upper) |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1635419 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 11.5 |
Image: |
2b/d |
Note: |
Co-expressed with Cd34 in the dorsal aorta and cardinal veins region. |
Specimen Label: |
2b/d |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1620419 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 11.5 |
Image: |
2b/d |
Note: |
Co-expressed with Cd34 in the dorsal aorta and cardinal veins region. |
Specimen Label: |
2b/d |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1633219 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 11.5 |
Image: |
2b/d |
Note: |
Co-expressed with Cd34 in the dorsal aorta and cardinal veins region. |
Specimen Label: |
2b/d |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7548952 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1620417 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7549028 |
Age: |
embryonic day 10.5 |
Image: |
3C tph2+/- |
Note: |
Increased number of cells co-expressing both Pecam1 and CD34 compared to control |
Specimen Label: |
3C tph2+/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2001 |
Journal: |
DNA Seq |
Title: |
Gene structure and alternative splicing of murine podocalyxin: a member of the CD34 sialomucin family. |
Volume: |
12 |
Issue: |
5-6 |
Pages: |
407-12 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd34/Cd34<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> |
Background: |
involves: 129S6/SvEvTac * C57BL/6NCrl |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1626717 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 10.5 |
Image: |
1d/f/g |
Note: |
Co-expressed with Cd34 in large cells with prominent nuclei in the yolk sac blood islands as aggregates. |
Specimen Label: |
1d/f/g |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1633217 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 10.5 |
Image: |
1d/f/g |
Note: |
Co-expressed with Cd34 in large cells with prominent nuclei in the yolk sac blood islands as aggregates. |
Specimen Label: |
1d/f/g |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1633219 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 11.5 |
Image: |
2f/h |
Note: |
Co-expressed with Cd34 in many prominent colonies of eosinophilic and nucleate cells over the entire fetal liver parenchyma. |
Specimen Label: |
2f/h |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1633219 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 11.5 |
Image: |
3b/d |
Note: |
Co-expressed with Cd34 in a number of cells with large nuclei in large fetal blood vessels in the chorioallantoic mesenchyme. |
Specimen Label: |
3b/d |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3187219 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 11.5 |
Image: |
3b/d |
Note: |
Co-expressed with Cd34 in a number of cells with large nuclei in large fetal blood vessels in the chorioallantoic mesenchyme. |
Specimen Label: |
3b/d |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1720319 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 11.5 |
Image: |
2f/h |
Note: |
Co-expressed with Cd34 in many prominent colonies of eosinophilic and nucleate cells over the entire fetal liver parenchyma. |
Specimen Label: |
2f/h |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7514398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-08-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3187819 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7514399 |
Age: |
embryonic day 11.5 |
Image: |
3b/d |
Note: |
Co-expressed with Cd34 in a number of cells with large nuclei in large fetal blood vessels in the chorioallantoic mesenchyme. |
Specimen Label: |
3b/d |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3528200 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2005-03-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1620419 |
Pattern: |
Single cells |
Stage: |
TS19 |
Assay Id: |
MGI:3528300 |
Age: |
embryonic day 11.5 |
Image: |
3E,F |
Note: |
A few relatively large cells staying on the wall of E11.5 dorsal aorta were positively stained. These cells expressing Dnmt3b were also stained with CD34 antibodies. |
Specimen Label: |
3E,F |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3528200 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2005-03-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1734919 |
Pattern: |
Single cells |
Stage: |
TS19 |
Assay Id: |
MGI:3528300 |
Age: |
embryonic day 11.5 |
Image: |
3H,I |
Note: |
A few circulating cells in the portal vein were positively stained. These cells expressing Dnmt3b were also stained with CD34 antibodies. |
Specimen Label: |
3H,I |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3528200 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2005-03-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1633219 |
Pattern: |
Single cells |
Stage: |
TS19 |
Assay Id: |
MGI:3528300 |
Age: |
embryonic day 11.5 |
Image: |
3H,I |
Note: |
A few circulating cells in the portal vein were positively stained. These cells expressing Dnmt3b were also stained with CD34 antibodies. |
Specimen Label: |
3H,I |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takeda T |
Year: |
2000 |
Journal: |
Mol Biol Cell |
Title: |
Expression of podocalyxin inhibits cell-cell adhesion and modifies junctional properties in Madin-Darby canine kidney cells. |
Volume: |
11 |
Issue: |
9 |
Pages: |
3219-32 |
|
•
•
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Protein Domain |
Type: |
Family |
Description: |
This family consists of several mammalian CD34 antigen proteins. The CD34 antigen is a human leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. CD34 is a phosphoprotein. Activation of protein kinase C (PKC) has been found to enhance CD34 phosphorylation [, ]. This family contains several eukaryotic podocalyxin proteins. Podocalyxin is a major membrane protein of the glomerular epithelium and is thought to be involved in maintenance of the architecture of the foot processes and filtration slits characteristic of this unique epithelium by virtue of its high negative charge. Podocalyxin functions as an anti-adhesin that maintains an open filtration pathway between neighbouring foot processes in the glomerular epithelium by charge repulsion []. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
603
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
539
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
603
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Fragment?: |
false |
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CL Term |
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Allele |
Name: |
transgene insertion MF6, GENSAT Project at Rockefeller University |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
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Allele |
Name: |
transgene insertion 1, Daniel G Tenen |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence, Transactivator |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
150
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Fragment?: |
true |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
178
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Fragment?: |
true |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
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Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
465
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Fragment?: |
false |
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Protein Domain |
Type: |
Family |
Description: |
Podocalyxin-like protein 2 (PODXL2), also known as Endoglycan, is a ligand for the vascular selectins []. It belongs to the CD34 family, whose members contain an N-terminal acidic region appended to the sialomucin domain []. |
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Strain |
Attribute String: |
mutant stock, transgenic |
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Allele |
Name: |
transgene insertion 29, Daniel G Tenen |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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Strain |
Attribute String: |
congenic, mutant strain, transgenic |
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Genotype |
Symbol: |
Tg(CD34-tTA,-CD34)1Dgt/? |
Background: |
involves: FVB/N |
Zygosity: |
ot |
Has Mutant Allele: |
true |
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Publication |
First Author: |
Bernitz JM |
Year: |
2016 |
Journal: |
Cell |
Title: |
Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions. |
Volume: |
167 |
Issue: |
5 |
Pages: |
1296-1309.e10 |
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Genotype |
Symbol: |
Tg(CD34)29Dgt/? |
Background: |
involves: FVB/N |
Zygosity: |
ot |
Has Mutant Allele: |
true |
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HT Experiment |
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Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
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Publication |
First Author: |
Strasser A |
Year: |
1993 |
Journal: |
Oncogene |
Title: |
E mu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1-9 |
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Publication |
First Author: |
Dao MA |
Year: |
2000 |
Journal: |
Leukemia |
Title: |
CD34: to select or not to select? That is the question. |
Volume: |
14 |
Issue: |
5 |
Pages: |
773-6 |
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•
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Publication |
First Author: |
le Viseur C |
Year: |
2008 |
Journal: |
Cancer Cell |
Title: |
In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties. |
Volume: |
14 |
Issue: |
1 |
Pages: |
47-58 |
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HT Experiment |
Series Id: |
GSE68725 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
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HT Experiment |
Series Id: |
GSE68724 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
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HT Experiment |
Series Id: |
GSE68723 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
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HT Experiment |
Series Id: |
E-GEOD-68958 |
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
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Publication |
First Author: |
Girousse A |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
The Release of Adipose Stromal Cells from Subcutaneous Adipose Tissue Regulates Ectopic Intramuscular Adipocyte Deposition. |
Volume: |
27 |
Issue: |
2 |
Pages: |
323-333.e5 |
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Publication |
First Author: |
Bistrup A |
Year: |
1999 |
Journal: |
J Cell Biol |
Title: |
Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. |
Volume: |
145 |
Issue: |
4 |
Pages: |
899-910 |
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Publication |
First Author: |
Buffolo M |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling. |
Volume: |
29 |
Issue: |
2 |
Pages: |
270-282.e5 |
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Publication |
First Author: |
Freitas I |
Year: |
2003 |
Journal: |
Anticancer Res |
Title: |
Stem cell recruitment and liver de-differentiation in MMTV-neu (ErbB-2) transgenic mice. |
Volume: |
23 |
Issue: |
5A |
Pages: |
3783-94 |
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Publication |
First Author: |
Boitano AE |
Year: |
2010 |
Journal: |
Science |
Title: |
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. |
Volume: |
329 |
Issue: |
5997 |
Pages: |
1345-8 |
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Publication |
First Author: |
Jia Q |
Year: |
2017 |
Journal: |
Biochem Biophys Res Commun |
Title: |
miR-17-92 promotes leukemogenesis in chronic myeloid leukemia via targeting A20 and activation of NF-κB signaling. |
Volume: |
487 |
Issue: |
4 |
Pages: |
868-874 |
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Publication |
First Author: |
Law S |
Year: |
2001 |
Journal: |
Immunol Lett |
Title: |
Facilitation of functional compartmentalization of bone marrow cells in leukemic mice by biological response modifiers: an immunotherapeutic approach. |
Volume: |
76 |
Issue: |
3 |
Pages: |
145-52 |
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Publication |
First Author: |
Ottersbach K |
Year: |
2005 |
Journal: |
Dev Cell |
Title: |
The murine placenta contains hematopoietic stem cells within the vascular labyrinth region. |
Volume: |
8 |
Issue: |
3 |
Pages: |
377-87 |
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Publication |
First Author: |
Jensen UB |
Year: |
2008 |
Journal: |
J Cell Sci |
Title: |
A distinct population of clonogenic and multipotent murine follicular keratinocytes residing in the upper isthmus. |
Volume: |
121 |
Issue: |
Pt 5 |
Pages: |
609-17 |
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Publication |
First Author: |
McKinney-Freeman SL |
Year: |
2009 |
Journal: |
Blood |
Title: |
Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells. |
Volume: |
114 |
Issue: |
2 |
Pages: |
268-78 |
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•
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Publication |
First Author: |
Santini MP |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
IGF-1Ea induces vessel formation after injury and mediates bone marrow and heart cross-talk through the expression of specific cytokines. |
Volume: |
410 |
Issue: |
2 |
Pages: |
201-7 |
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Publication |
First Author: |
Zhang H |
Year: |
2014 |
Journal: |
Stem Cells |
Title: |
Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. |
Volume: |
32 |
Issue: |
1 |
Pages: |
191-203 |
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Publication |
First Author: |
GarcÃa-Prat L |
Year: |
2020 |
Journal: |
Nat Cell Biol |
Title: |
FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age. |
Volume: |
22 |
Issue: |
11 |
Pages: |
1307-1318 |
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Publication |
First Author: |
Zhang B |
Year: |
2017 |
Journal: |
J Cell Mol Med |
Title: |
Telocytes: a potential defender in the spleen of Npc1 mutant mice. |
Volume: |
21 |
Issue: |
5 |
Pages: |
848-859 |
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Publication |
First Author: |
Ming M |
Year: |
2014 |
Journal: |
Exp Dermatol |
Title: |
Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin. |
Volume: |
23 |
Issue: |
3 |
Pages: |
207-9 |
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Publication |
First Author: |
Sastourné-Arrey Q |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury. |
Volume: |
14 |
Issue: |
1 |
Pages: |
80 |
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