Type |
Details |
Score |
Publication |
First Author: |
Bruzzaniti A |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
Dynamin reduces Pyk2 Y402 phosphorylation and SRC binding in osteoclasts. |
Volume: |
29 |
Issue: |
13 |
Pages: |
3644-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fisslthaler B |
Year: |
2008 |
Journal: |
Circ Res |
Title: |
Inhibition of endothelial nitric oxide synthase activity by proline-rich tyrosine kinase 2 in response to fluid shear stress and insulin. |
Volume: |
102 |
Issue: |
12 |
Pages: |
1520-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pierau M |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation. |
Volume: |
183 |
Issue: |
10 |
Pages: |
6124-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martel-Gallegos G |
Year: |
2013 |
Journal: |
Biochim Biophys Acta |
Title: |
Oxidative stress induced by P2X7 receptor stimulation in murine macrophages is mediated by c-Src/Pyk2 and ERK1/2. |
Volume: |
1830 |
Issue: |
10 |
Pages: |
4650-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chung IC |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis. |
Volume: |
6 |
|
Pages: |
36214 |
|
•
•
•
•
•
|
Publication |
First Author: |
Canino J |
Year: |
2020 |
Journal: |
Biochim Biophys Acta Mol Cell Res |
Title: |
The proline-rich tyrosine kinase Pyk2 modulates integrin-mediated neutrophil adhesion and reactive oxygen species generation. |
Volume: |
1867 |
Issue: |
10 |
Pages: |
118799 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ptk2/Ptk2 Tg(Tek-cre)12Flv/? |
Background: |
involves: 129P2/OlaHsd * C3H * C57BL/6 * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ptk2/Ptk2 Tg(KRT5-cre)5132Jlj/? |
Background: |
involves: 129X1/SvJ * C57BL/6 * CBA * DBA/2J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ptk2/Ptk2<+> |
Background: |
CBA.Cg-Ptk2 |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fyn/Fyn Ptk2/Ptk2<+> |
Background: |
involves: 129X1/SvJ * C57BL/6 * CBA |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ptk2/Ptk2 Tg(Tek-cre)12Flv/? |
Background: |
involves: 129P2/OlaHsd * C3H * C57BL/6 * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Neurod6/Neurod6<+> Ptk2/Ptk2 |
Background: |
involves: 129S1/Sv * 129X1/SvJ * CD-1 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ptk2/Ptk2<+> |
Background: |
involves: C57BL/6 * CBA |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ptk2/Ptk2 Trp53/Trp53 |
Background: |
involves: C57BL/6 * CBA |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1736
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1572
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1804
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Watanabe N |
Year: |
2005 |
Journal: |
Mol Cell Biochem |
Title: |
Leupaxin binds to PEST domain tyrosine phosphatase PEP. |
Volume: |
269 |
Issue: |
1-2 |
Pages: |
13-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Canobbio I |
Year: |
2015 |
Journal: |
Biochem J |
Title: |
The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets. |
Volume: |
469 |
Issue: |
2 |
Pages: |
199-210 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marqués M |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication. |
Volume: |
106 |
Issue: |
18 |
Pages: |
7525-30 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, endonuclease-mediated mutation, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Myl2/Myl2<+> Ptk2/Ptk2 |
Background: |
involves: 129P2/OlaHsd * 129S4/SvJae |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ptk2/Ptk2<+> Trp53/Trp53 |
Background: |
involves: C57BL/6 * CBA |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1838
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1497
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1739
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Malgaretti N |
Year: |
1997 |
Journal: |
J Biol Chem |
Title: |
Mmot1, a new helix-loop-helix transcription factor gene displaying a sharp expression boundary in the embryonic mouse brain. |
Volume: |
272 |
Issue: |
28 |
Pages: |
17632-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Balasubramanian S |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
β3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouse. |
Volume: |
7 |
Issue: |
9 |
Pages: |
e45076 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iskander SM |
Year: |
2018 |
Journal: |
J Am Soc Nephrol |
Title: |
Protein Kinase 2β Is Expressed in Neural Crest-Derived Urinary Pacemaker Cells and Required for Pyeloureteric Contraction. |
Volume: |
29 |
Issue: |
4 |
Pages: |
1198-1209 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1464
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1372
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
728
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1487
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1379
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1453
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Böttger V |
Year: |
1995 |
Journal: |
Eur J Biochem |
Title: |
Epitope mapping of monoclonal antibodies to keratin 19 using keratin fragments, synthetic peptides and phage peptide libraries. |
Volume: |
231 |
Issue: |
2 |
Pages: |
475-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bjarnadottir M |
Year: |
2007 |
Journal: |
J Neurosci |
Title: |
Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/- knock-outs compared with wild-type mice. |
Volume: |
27 |
Issue: |
17 |
Pages: |
4519-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamoto S |
Year: |
2008 |
Journal: |
Nat Med |
Title: |
TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. |
Volume: |
14 |
Issue: |
7 |
Pages: |
738-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le HT |
Year: |
2006 |
Journal: |
J Neurochem |
Title: |
Reduced NMDA receptor tyrosine phosphorylation in PTPalpha-deficient mouse synaptosomes is accompanied by inhibition of four src family kinases and Pyk2: an upstream role for PTPalpha in NMDA receptor regulation. |
Volume: |
98 |
Issue: |
6 |
Pages: |
1798-809 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
798
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2477
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1052
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Ando-Akatsuka Y |
Year: |
1996 |
Journal: |
J Cell Biol |
Title: |
Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. |
Volume: |
133 |
Issue: |
1 |
Pages: |
43-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gueth-Hallonet C |
Year: |
1993 |
Journal: |
J Cell Sci |
Title: |
gamma-Tubulin is present in acentriolar MTOCs during early mouse development. |
Volume: |
105 ( Pt 1) |
|
Pages: |
157-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rothbarth K |
Year: |
1993 |
Journal: |
J Cell Sci |
Title: |
cDNA-derived molecular characteristics and antibodies to a new centrosome-associated and G2/M phase-prevalent protein. |
Volume: |
104 ( Pt 1) |
|
Pages: |
19-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith FJ |
Year: |
2002 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Cloning of human, murine, and marsupial keratin 7 and a survey of K7 expression in the mouse. |
Volume: |
297 |
Issue: |
4 |
Pages: |
818-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Porter RM |
Year: |
1998 |
Journal: |
J Biol Chem |
Title: |
cDNA cloning, expression, and assembly characteristics of mouse keratin 16. |
Volume: |
273 |
Issue: |
48 |
Pages: |
32265-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Masuhara M |
Year: |
2000 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains. |
Volume: |
268 |
Issue: |
3 |
Pages: |
697-703 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
535
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Papanicolaou KN |
Year: |
2012 |
Journal: |
Circ Res |
Title: |
Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. |
Volume: |
111 |
Issue: |
8 |
Pages: |
1012-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wajapeyee N |
Year: |
2013 |
Journal: |
Genes Dev |
Title: |
Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. |
Volume: |
27 |
Issue: |
20 |
Pages: |
2221-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung H |
Year: |
2018 |
Journal: |
Nat Neurosci |
Title: |
Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice. |
Volume: |
21 |
Issue: |
9 |
Pages: |
1218-1228 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mammalian Functional Genomics Centre |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|