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Search results 1201 to 1300 out of 3442 for Hprt

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Hits by Pathway

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Type Details Score
Genotype
Genotype
Symbol: Bmp2/Bmp2<+> Gpc3/Gpc3<+>
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: F2/F2<+>
Background: involves: 129P2/OlaHsd * Black Swiss
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Myf5/Myf5<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Atp1a1/Atp1a1<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * Black Swiss * CD-1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Atp1a1/Atp1a1
Background: involves: 129P2/OlaHsd * C57BL/6 * Black Swiss * CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Cdx1-cre)23Kem/?
Background: involves: C57BL/6 * FVB
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc Tg(Alb1-cre)7Gsc/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hbb-b1/Hbb-b1 Hbb-b2/Hbb-b2
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ring1/Ring1 Rnf2/Rnf2
Background: involves: 129 * C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ring1/Ring1 Rnf2/Rnf2
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Inhba/Inhba Tg(Pou5f1-EGFP)2Mnn/?
Background: involves: 129S7/SvEvBrd * C57BL/6J * CBA/CaJ
Zygosity: cx
Has Mutant Allele: true
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Publication
8894695 | J:35822
First Author: Engle SJ
Year: 1996
Journal: Hum Mol Genet
Title: HPRT-APRT-deficient mice are not a model for lesch-nyhan syndrome.
Volume: 5
Issue: 10
Pages: 1607-10
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Strain
MGI:5529809 | B6N.Cg-A<w-J> Hprt1<b-m3>
Attribute String: congenic, mutant strain, spontaneous mutation, deletion
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Strain
MGI:5657789 | (B6.Cg-A<w-J> Hprt1<b-m3>/Ems x 129S-Gt(ROSA)26Sor<tm1Sor>/J)F1
Attribute String: F1 hybrid
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Strain
MGI:3625515 | B6.129P2-Hprt1<b-m3>
Attribute String: spontaneous mutation, mutant strain, congenic
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Publication
31118497 | J:302829
First Author: Lu J
Year: 2019
Journal: Nat Rev Rheumatol
Title: Mouse models for human hyperuricaemia: a critical review.
Volume: 15
Issue: 7
Pages: 413-426
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Strain
MGI:4441511 | NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl> Hprt1<b-m3>/EshJ
Attribute String: congenic, mutant strain, spontaneous mutation, targeted mutation
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Publication
8027435 | J:17783
First Author: Heckroth JA
Year: 1994
Journal: J Comp Neurol
Title: A quantitative morphological analysis of the cerebellar nuclei in normal and lurcher mutant mice. II. Volumetric changes in cytological components.
Volume: 343
Issue: 1
Pages: 183-92
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Publication
1528024 | J:3354
First Author: Williamson DJ
Year: 1992
Journal: J Inherit Metab Dis
Title: Mouse models of hypoxanthine phosphoribosyltransferase deficiency.
Volume: 15
Issue: 4
Pages: 665-73
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Publication
2292045 | J:2057
First Author: Jinnah HA
Year: 1990
Journal: Brain Res Bull
Title: Animal models of Lesch-Nyhan syndrome.
Volume: 25
Issue: 3
Pages: 467-75
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Strain
MGI:5575501 | (129-Hprt1<b-m3> x C57BL/6)F1
Attribute String: F1 hybrid
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Strain
MGI:3706233 | 129P2/OlaHsd-Hprt1<b-m3>
Attribute String: coisogenic, mutant strain, spontaneous mutation
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Strain
MGI:2162563 | B6.129P2-Hprt1<b-m3>/J
Attribute String: congenic, mutant strain, spontaneous mutation
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Strain
MGI:5654707 | C57BL/6J-Hprt1<b-m3>
Attribute String: mutant strain, spontaneous mutation, congenic
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Strain
MGI:5656446 | (B6.129P2-Hprt1<b-m3>/J x 129S-Gt(ROSA)26Sor<tm1Sor>/J)F1
Attribute String: F1 hybrid, spontaneous mutation, targeted mutation
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Publication
11882343 | J:75479
First Author: Visser JE
Year: 2002
Journal: Brain Res Dev Brain Res
Title: Oxidative stress and dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Volume: 133
Issue: 2
Pages: 127-39
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Publication
11297820 | J:107966
First Author: Boer P
Year: 2001
Journal: Neurosci Lett
Title: Decelerated rate of dendrite outgrowth from dopaminergic neurons in primary cultures from brains of hypoxanthine phosphoribosyltransferase-deficient knockout mice.
Volume: 303
Issue: 1
Pages: 45-8
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Publication
29305058 | J:271791
 
First Author: Zizzo MG
Year: 2018
Journal: Auton Neurosci
Title: Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease.
Volume: 210
Pages: 55-64
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Publication
35660973 | J:326670
First Author: Witteveen JS
Year: 2022
Journal: Cell Mol Life Sci
Title: HGprt deficiency disrupts dopaminergic circuit development in a genetic mouse model of Lesch-Nyhan disease.
Volume: 79
Issue: 6
Pages: 341
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Publication
1777100 | J:1847
First Author: Jinnah HA
Year: 1991
Journal: Behav Neurosci
Title: Amphetamine-induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome.
Volume: 105
Issue: 6
Pages: 1004-12
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Publication
23340293 | J:202087
First Author: Kamiyama H
Year: 2013
Journal: Clin Cancer Res
Title: Personalized chemotherapy profiling using cancer cell lines from selectable mice.
Volume: 19
Issue: 5
Pages: 1139-46
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Publication
28204548 | J:249960
First Author: Varghese S
Year: 2017
Journal: Nucleic Acids Res
Title: In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis.
Volume: 45
Issue: 4
Pages: 2029-2039
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Publication
23584856 | J:198465
First Author: Wattanachanya L
Year: 2013
Journal: Endocrinology
Title: Increased bone mass in mice lacking the adipokine apelin.
Volume: 154
Issue: 6
Pages: 2069-80
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Publication
10037486 | J:53129
First Author: Pelled D
Year: 1999
Journal: J Neurochem
Title: Abnormal purine and pyrimidine nucleotide content in primary astroglia cultures from hypoxanthine-guanine phosphoribosyltransferase-deficient transgenic mice.
Volume: 72
Issue: 3
Pages: 1139-45
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Genotype
Genotype
Symbol: Hprt1/? Impdh1/Impdh1
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/? Impdh2/Impdh2<+>
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/?
Background: B6.129P2-Hprt1
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/?
Background: involves: 129P2/OlaHsd
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/Hprt1
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/Hprt1
Background: B6.129P2-Hprt1
Zygosity: hm
Has Mutant Allele: true
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Publication
30765420 | J:270567
     
First Author: Korecki AJ
Year: 2019
Journal: Genetics
Title: Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain; Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele.
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Publication
24761428 | J:212452
 
First Author: de Leeuw CN
Year: 2014
Journal: Mol Ther Methods Clin Dev
Title: Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors.
Volume: 1
Pages: 5
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Publication
20211139 | J:167955
First Author: Greer PL
Year: 2010
Journal: Cell
Title: The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc.
Volume: 140
Issue: 5
Pages: 704-16
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Publication
22711701 | J:185266
First Author: Llano E
Year: 2012
Journal: J Cell Biol
Title: Meiotic cohesin complexes are essential for the formation of the axial element in mice.
Volume: 197
Issue: 7
Pages: 877-85
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Publication
11606457 | J:72752
First Author: Durlinger AL
Year: 2001
Journal: Endocrinology
Title: Anti-Müllerian hormone attenuates the effects of FSH on follicle development in the mouse ovary.
Volume: 142
Issue: 11
Pages: 4891-9
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Publication
15161660 | J:91094
First Author: Paisley D
Year: 2004
Journal: Am J Pathol
Title: Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout mice.
Volume: 164
Issue: 6
Pages: 2279-88
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Publication
9426063 | J:45017
First Author: de Boer J
Year: 1998
Journal: Cancer Res
Title: Disruption of the mouse xeroderma pigmentosum group D DNA repair/basal transcription gene results in preimplantation lethality.
Volume: 58
Issue: 1
Pages: 89-94
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Publication
15967816 | J:99636
First Author: Curino AC
Year: 2005
Journal: J Cell Biol
Title: Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy.
Volume: 169
Issue: 6
Pages: 977-85
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Publication
16359901 | J:104662
First Author: Cao R
Year: 2005
Journal: Mol Cell
Title: Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing.
Volume: 20
Issue: 6
Pages: 845-54
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Publication
20488244 | J:162428
First Author: Matte A
Year: 2010
Journal: Free Radic Biol Med
Title: Peroxiredoxin-2 expression is increased in beta-thalassemic mouse red cells but is displaced from the membrane as a marker of oxidative stress.
Volume: 49
Issue: 3
Pages: 457-66
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Publication
15825168 | J:99670
First Author: Mann EA
Year: 2005
Journal: Int J Cancer
Title: Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model.
Volume: 116
Issue: 4
Pages: 500-5
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Publication
28418886 | J:274113
First Author: Romain B
Year: 2017
Journal: Oncotarget
Title: Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration.
Volume: 8
Issue: 24
Pages: 38351-38366
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Publication
19593386 | J:151594
First Author: Zoltewicz JS
Year: 2009
Journal: PLoS One
Title: Wnt signaling is regulated by endoplasmic reticulum retention.
Volume: 4
Issue: 7
Pages: e6191
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Publication
21447558 | J:171272
First Author: Rinon A
Year: 2011
Journal: Development
Title: p53 coordinates cranial neural crest cell growth and epithelial-mesenchymal transition/delamination processes.
Volume: 138
Issue: 9
Pages: 1827-38
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Publication
23383107 | J:195912
First Author: Haefliger JA
Year: 2013
Journal: PLoS One
Title: Reduction of connexin36 content by ICER-1 contributes to insulin-secreting cells apoptosis induced by oxidized LDL particles.
Volume: 8
Issue: 1
Pages: e55198
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Publication
16002705 | J:100733
First Author: Chen M
Year: 2005
Journal: J Immunol
Title: Hepatocytes express abundant surface class I MHC and efficiently use transporter associated with antigen processing, tapasin, and low molecular weight polypeptide proteasome subunit components of antigen processing and presentation pathway.
Volume: 175
Issue: 2
Pages: 1047-55
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Publication
19864563 | J:158310
First Author: Thams S
Year: 2009
Journal: J Neurosci
Title: Classical major histocompatibility complex class I molecules in motoneurons: new actors at the neuromuscular junction.
Volume: 29
Issue: 43
Pages: 13503-15
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Publication
29376892 | J:260798
First Author: Stavrou EX
Year: 2018
Journal: J Clin Invest
Title: Factor XII and uPAR upregulate neutrophil functions to influence wound healing.
Volume: 128
Issue: 3
Pages: 944-959
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Publication
19391114 | J:149892
First Author: Uchimura T
Year: 2009
Journal: Genesis
Title: Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development.
Volume: 47
Issue: 6
Pages: 374-84
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Publication
12393413 | J:115559
First Author: Cardoso EM
Year: 2002
Journal: Blood
Title: Increased hepatic iron in mice lacking classical MHC class I molecules.
Volume: 100
Issue: 12
Pages: 4239-41
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Publication
14568937 | J:119214
First Author: Hart G
Year: 2003
Journal: J Immunol
Title: Ly49D receptor expressed on immature B cells regulates their IFN-gamma secretion, actin polymerization, and homing.
Volume: 171
Issue: 9
Pages: 4630-8
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Publication
17307940 | J:121876
First Author: Mullarky IK
Year: 2007
Journal: Infect Immun
Title: Gamma interferon suppresses erythropoiesis via interleukin-15.
Volume: 75
Issue: 5
Pages: 2630-3
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Publication
37727456 | J:340792
 
First Author: Whiley PAF
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure.
Volume: 14
Pages: 1234712
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Publication
35721752 | J:325984
 
First Author: Moody SC
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: The Impact of Activin A on Fetal Gonocytes: Chronic Versus Acute Exposure Outcomes.
Volume: 13
Pages: 896747
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Publication
10379885 | J:55802
First Author: Kumar TR
Year: 1999
Journal: Mol Endocrinol
Title: Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis.
Volume: 13
Issue: 6
Pages: 851-65
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Publication
9716414 | J:49552
First Author: Ferguson CA
Year: 1998
Journal: Genes Dev
Title: Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition.
Volume: 12
Issue: 16
Pages: 2636-49
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Publication
7885473 | J:23923
First Author: Matzuk MM
Year: 1995
Journal: Nature
Title: Functional analysis of activins during mammalian development.
Volume: 374
Issue: 6520
Pages: 354-6
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Publication
15580568 | J:95138
First Author: Inanlou MR
Year: 2005
Journal: Dev Dyn
Title: Abnormal development of the intercostal muscles and the rib cage in Myf5-/- embryos leads to pulmonary hypoplasia.
Volume: 232
Issue: 1
Pages: 43-54
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Publication
10725239 | J:60987
First Author: Kablar B
Year: 2000
Journal: Development
Title: Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent.
Volume: 127
Issue: 8
Pages: 1627-39
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Publication
23254194 | J:194605
First Author: Kenny S
Year: 2013
Journal: Endocrinology
Title: Gastric expression of plasminogen activator inhibitor (PAI)-1 is associated with hyperphagia and obesity in mice.
Volume: 154
Issue: 2
Pages: 718-26
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Publication
20228268 | J:161559
First Author: LaRusch GA
Year: 2010
Journal: Blood
Title: Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis.
Volume: 115
Issue: 24
Pages: 5111-20
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Publication
9787139 | J:114200
First Author: Russell JE
Year: 1998
Journal: Blood
Title: Reversal of lethal alpha- and beta-thalassemias in mice by expression of human embryonic globins.
Volume: 92
Issue: 9
Pages: 3057-63
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Publication
32745462 | J:297475
First Author: Ghoti H
Year: 2020
Journal: Am J Pathol
Title: Heparanase Level and Procoagulant Activity Are Increased in Thalassemia and Attenuated by Janus Kinase 2 Inhibition.
Volume: 190
Issue: 10
Pages: 2146-2154
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Publication
30209118 | J:269870
First Author: Artuso I
Year: 2018
Journal: Blood
Title: Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model.
Volume: 132
Issue: 21
Pages: 2286-2297
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Publication
19734452 | J:154187
First Author: Chen ML
Year: 2009
Journal: Blood
Title: Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction.
Volume: 114
Issue: 19
Pages: 4045-53
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Publication
17493845 | J:141719
First Author: Voon HP
Year: 2007
Journal: Blood Cells Mol Dis
Title: Co-inheritance of alpha- and beta-thalassaemia in mice ameliorates thalassaemic phenotype.
Volume: 39
Issue: 2
Pages: 184-8
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Publication
26058667 | J:294892
First Author: Matte A
Year: 2015
Journal: Antioxid Redox Signal
Title: The Interplay Between Peroxiredoxin-2 and Nuclear Factor-Erythroid 2 Is Important in Limiting Oxidative Mediated Dysfunction in β-Thalassemic Erythropoiesis.
Volume: 23
Issue: 16
Pages: 1284-97
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Publication
23499761 | J:214895
First Author: Nabors LK
Year: 2013
Journal: Exp Hematol
Title: Overlapping roles for endothelial selectins in murine hematopoietic stem/progenitor cell homing to bone marrow.
Volume: 41
Issue: 7
Pages: 588-96
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Publication
9329976 | J:101979
First Author: Munoz FM
Year: 1997
Journal: J Clin Invest
Title: Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice.
Volume: 100
Issue: 8
Pages: 2099-106
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Publication
11466371 | J:120485
First Author: Chun T
Year: 2001
Journal: J Immunol
Title: Functional roles of TAP and tapasin in the assembly of M3-N-formylated peptide complexes.
Volume: 167
Issue: 3
Pages: 1507-14
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Publication
23863903 | J:205830
First Author: Kanaseki T
Year: 2013
Journal: J Immunol
Title: ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides.
Volume: 191
Issue: 4
Pages: 1547-55
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Publication
15112318 | J:109752
First Author: Trousdale RK
Year: 2004
Journal: Mol Reprod Dev
Title: Bromodomain containing 2 (Brd2) is expressed in distinct patterns during ovarian folliculogenesis independent of FSH or GDF9 action.
Volume: 68
Issue: 3
Pages: 261-8
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Publication
12488339 | J:81408
First Author: Baker PJ
Year: 2003
Journal: Endocrinology
Title: Failure of normal Leydig cell development in follicle-stimulating hormone (FSH) receptor-deficient mice, but not FSHbeta-deficient mice: role for constitutive FSH receptor activity.
Volume: 144
Issue: 1
Pages: 138-45
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Publication
30060157 | J:265699
First Author: Roy S
Year: 2018
Journal: Endocrinology
Title: Oocyte-Derived Factors (GDF9 and BMP15) and FSH Regulate AMH Expression Via Modulation of H3K27AC in Granulosa Cells.
Volume: 159
Issue: 9
Pages: 3433-3445
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Publication
14551232 | J:87442
First Author: Johnston H
Year: 2004
Journal: Endocrinology
Title: Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse.
Volume: 145
Issue: 1
Pages: 318-29
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Publication
15837572 | J:105115
First Author: Murtie JC
Year: 2005
Journal: Neurobiol Dis
Title: PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination.
Volume: 19
Issue: 1-2
Pages: 171-82
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Publication
7477327 | J:29811
First Author: Jones SN
Year: 1995
Journal: Nature
Title: Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53.
Volume: 378
Issue: 6553
Pages: 206-8
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Publication
8943068 | J:37047
First Author: Jones SN
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.
Volume: 93
Issue: 24
Pages: 14106-11
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Publication
11857802 | J:75119
First Author: Steinman HA
Year: 2002
Journal: Genesis
Title: Generation of an Mdm2 conditional allele in mice.
Volume: 32
Issue: 2
Pages: 142-4
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Publication
24163099 | J:211903
First Author: Frum RA
Year: 2014
Journal: Nucleic Acids Res
Title: The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing.
Volume: 42
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Pages: 926-40
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Journal: Dev Biol
Title: FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region.
Volume: 297
Issue: 1
Pages: 141-57
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Strain
MGI:2162984 | B6.129S7-Sod2<tm1Leb>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
8790408 | J:36148
First Author: Lebovitz RM
Year: 1996
Journal: Proc Natl Acad Sci U S A
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Pages: 9782-7
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Title: Age-dependent mitochondrial energy dynamics in the mice heart: role of superoxide dismutase-2.
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Journal: PLoS One
Title: Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle.
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Issue: 12
Pages: e81879
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Year: 2022
Journal: Physiol Rep
Title: Heterozygous SOD2 deletion selectively impairs SERCA function in the soleus of female mice.
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Issue: 10
Pages: e15285
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Publication
10598322 | J:103295
First Author: Jackson RM
Year: 1999
Journal: Exp Lung Res
Title: Survival, lung injury, and lung protein nitration in heterozygous MnSOD knockout mice in hyperoxia.
Volume: 25
Issue: 7
Pages: 631-46
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Journal: Stem Cells
Title: Mitochondrial superoxide production negatively regulates neural progenitor proliferation and cerebral cortical development.
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Publication
14980699 | J:88798
First Author: Liang LP
Year: 2004
Journal: Free Radic Biol Med
Title: Mitochondrial oxidative stress and increased seizure susceptibility in Sod2(-/+) mice.
Volume: 36
Issue: 5
Pages: 542-54
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Publication
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Year: 2008
Journal: Toxicol Appl Pharmacol
Title: Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2(+/-) mice: two-stage oxidative injury.
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