|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 2801 to 2900 out of 3295 for Kras

<< First    < Previous  |  Next >    Last >>
0.042s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
29202479 | J:258828
First Author: Shoag J
Year: 2018
Journal: J Clin Invest
Title: SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG.
Volume: 128
Issue: 1
Pages: 381-386
•
•
•
•
•
Publication
27728805 | J:236713
First Author: Dardenne E
Year: 2016
Journal: Cancer Cell
Title: N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Volume: 30
Issue: 4
Pages: 563-577
•
•
•
•
•
Publication
31277777 | J:309459
First Author: Shinde D
Year: 2019
Journal: Eur Urol Oncol
Title: Transcriptional Reprogramming and Inhibition of Tumor-propagating Stem-like Cells by EC-8042 in ERG-positive Prostate Cancer.
Volume: 2
Issue: 4
Pages: 415-424
•
•
•
•
•
Publication
20679199 | J:163589
First Author: Furic L
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.
Volume: 107
Issue: 32
Pages: 14134-9
•
•
•
•
•
Publication
30333152 | J:271158
First Author: Elfandy H
Year: 2019
Journal: Mol Cancer Res
Title: Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate.
Volume: 17
Issue: 2
Pages: 446-456
•
•
•
•
•
Publication
23856248 | J:201832
First Author: Zheng Y
Year: 2013
Journal: Cancer Res
Title: PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer.
Volume: 73
Issue: 17
Pages: 5426-37
•
•
•
•
•
Publication
29335436 | J:257713
First Author: Chen M
Year: 2018
Journal: Nat Commun
Title: Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism.
Volume: 9
Issue: 1
Pages: 159
•
•
•
•
•
Publication
19176516 | J:261276
First Author: Nardella C
Year: 2009
Journal: Sci Signal
Title: Differential requirement of mTOR in postmitotic tissues and tumorigenesis.
Volume: 2
Issue: 55
Pages: ra2
•
•
•
•
•
Publication
28274958 | J:243131
First Author: Patnaik A
Year: 2017
Journal: Cancer Discov
Title: Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity.
Volume: 7
Issue: 7
Pages: 750-765
•
•
•
•
•
Publication
29335545 | J:260988
First Author: Chen M
Year: 2018
Journal: Nat Genet
Title: An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
Volume: 50
Issue: 2
Pages: 206-218
•
•
•
•
•
Publication
28807943 | J:245648
First Author: Bainor AJ
Year: 2017
Journal: Cancer Res
Title: Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence.
Volume: 77
Issue: 19
Pages: 5339-5348
•
•
•
•
•
Publication
33186519 | J:300350
First Author: Guccini I
Year: 2021
Journal: Cancer Cell
Title: Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis.
Volume: 39
Issue: 1
Pages: 68-82.e9
•
•
•
•
•
Publication
28603917 | J:245657
First Author: Sackmann Sala L
Year: 2017
Journal: J Pathol
Title: A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours.
Volume: 243
Issue: 1
Pages: 51-64
•
•
•
•
•
Publication
36928314 | J:352792
 
First Author: Wang ME
Year: 2023
Journal: J Clin Invest
Title: RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis.
Volume: 133
Issue: 10
•
•
•
•
•
Publication
29309058 | J:275855
First Author: Bezzi M
Year: 2018
Journal: Nat Med
Title: Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms.
Volume: 24
Issue: 2
Pages: 165-175
•
•
•
•
•
Publication
36868226 | J:347460
First Author: Bancaro N
Year: 2023
Journal: Cancer Cell
Title: Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer.
Volume: 41
Issue: 3
Pages: 602-619.e11
•
•
•
•
•
Publication
33500545 | J:306413
First Author: Albino D
Year: 2021
Journal: Commun Biol
Title: Circulating extracellular vesicles release oncogenic miR-424 in experimental models and patients with aggressive prostate cancer.
Volume: 4
Issue: 1
Pages: 119
•
•
•
•
•
Publication
35216332 | J:321513
 
First Author: Sato H
Year: 2022
Journal: Int J Mol Sci
Title: Specific Gut Microbial Environment in Lard Diet-Induced Prostate Cancer Development and Progression.
Volume: 23
Issue: 4
•
•
•
•
•
Publication
37386128 | J:338792
First Author: Vlajic K
Year: 2023
Journal: Oncogene
Title: Appearance of tuft cells during prostate cancer progression.
Volume: 42
Issue: 31
Pages: 2374-2385
•
•
•
•
•
Publication
26206718 | J:224835
First Author: Belair CD
Year: 2015
Journal: EMBO Rep
Title: DGCR8 is essential for tumor progression following PTEN loss in the prostate.
Volume: 16
Issue: 9
Pages: 1219-32
•
•
•
•
•
Publication
29142193 | J:338791
First Author: Wozniak DJ
Year: 2017
Journal: Nat Commun
Title: PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.
Volume: 8
Issue: 1
Pages: 1508
•
•
•
•
•
Publication
32219437 | J:289861
 
First Author: Hermanova I
Year: 2020
Journal: J Exp Med
Title: Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer.
Volume: 217
Issue: 6
•
•
•
•
•
Publication
34230470 | J:307918
First Author: Zoma M
Year: 2021
Journal: Nat Commun
Title: EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer.
Volume: 12
Issue: 1
Pages: 4147
•
•
•
•
•
Publication
35584006 | J:326292
First Author: Davidson SM
Year: 2022
Journal: Cancer Res
Title: Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.
Volume: 82
Issue: 13
Pages: 2403-2416
•
•
•
•
•
Publication
25099011 | J:216207
First Author: Xie Y
Year: 2014
Journal: Mol Endocrinol
Title: Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancer.
Volume: 28
Issue: 10
Pages: 1629-39
•
•
•
•
•
Publication
29056325 | J:251968
First Author: Malek M
Year: 2017
Journal: Mol Cell
Title: PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.
Volume: 68
Issue: 3
Pages: 566-580.e10
•
•
•
•
•
Publication
32701507 | J:302324
First Author: Li F
Year: 2020
Journal: J Clin Invest
Title: ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming.
Volume: 130
Issue: 11
Pages: 5924-5941
•
•
•
•
•
Publication
23563312 | J:201460
First Author: Hanna SC
Year: 2013
Journal: J Clin Invest
Title: HIF1α and HIF2α independently activate SRC to promote melanoma metastases.
Volume: 123
Issue: 5
Pages: 2078-93
•
•
•
•
•
Publication
18840652 | J:141132
First Author: Vaahtomeri K
Year: 2008
Journal: J Cell Sci
Title: Lkb1 is required for TGFbeta-mediated myofibroblast differentiation.
Volume: 121
Issue: Pt 21
Pages: 3531-40
•
•
•
•
•
Strain
MGI:5897667 | 129.Cg-Kras<tm4Tyj> Tg(Tpo-cre)1Shk Pten<tm2.1Ppp>
Attribute String: congenic, mutant strain, targeted mutation, transgenic
•
•
•
•
•
Publication
32807988 | J:305876
First Author: Guo W
Year: 2020
Journal: Nat Genet
Title: Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips.
Volume: 52
Issue: 9
Pages: 908-918
•
•
•
•
•
Publication
28273450 | J:251063
First Author: Chen CF
Year: 2017
Journal: Cell Rep
Title: ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment.
Volume: 18
Issue: 10
Pages: 2331-2342
•
•
•
•
•
Publication
24691994 | J:210809
First Author: Le Mercier I
Year: 2014
Journal: Cancer Res
Title: VISTA Regulates the Development of Protective Antitumor Immunity.
Volume: 74
Issue: 7
Pages: 1933-44
•
•
•
•
•
Strain
MGI:6335591 | STOCK Pten<tm2.1Ppp> Tg(Alb1-cre) Tg(Alb1-HCVN)35Sml/Orl
Attribute String: mutant stock, targeted mutation, transgenic
•
•
•
•
•
Strain
MGI:4868761 | 129S1.Cg-Pten<tm2.1Ppp> Tg(TPO-cre)1Shk
Attribute String: transgenic, mutant strain, targeted mutation
•
•
•
•
•
Publication
24145418 | J:202916
First Author: Yuan P
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.
Volume: 110
Issue: 45
Pages: 18226-31
•
•
•
•
•
Publication
24200692 | J:207627
First Author: Marsh Durban V
Year: 2013
Journal: J Clin Invest
Title: Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma.
Volume: 123
Issue: 12
Pages: 5104-18
•
•
•
•
•
Publication
23796563 | J:200610
First Author: Antico Arciuch VG
Year: 2013
Journal: Cancer Res
Title: Inhibition of AMPK and Krebs cycle gene expression drives metabolic remodeling of Pten-deficient preneoplastic thyroid cells.
Volume: 73
Issue: 17
Pages: 5459-72
•
•
•
•
•
Publication
36368445 | J:332391
     
First Author: Dong B
Year: 2022
Journal: J Invest Dermatol
Title: FZD6 Promotes Melanoma Cell Invasion but Not Proliferation by Regulating Canonical Wnt Signaling and Epithelial‒Mesenchymal Transition.
•
•
•
•
•
Publication
22302806 | J:181347
First Author: Xiong Q
Year: 2012
Journal: J Neurosci
Title: PTEN regulation of local and long-range connections in mouse auditory cortex.
Volume: 32
Issue: 5
Pages: 1643-52
•
•
•
•
•
Publication
27052162 | J:235087
First Author: Katlinskaya YV
Year: 2016
Journal: Cell Rep
Title: Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression.
Volume: 15
Issue: 1
Pages: 171-80
•
•
•
•
•
Publication
28174173 | J:240401
First Author: Wan L
Year: 2017
Journal: Cancer Discov
Title: The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.
Volume: 7
Issue: 4
Pages: 424-441
•
•
•
•
•
Publication
37270599 | J:354056
First Author: Yang J
Year: 2023
Journal: Mol Cancer
Title: CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth.
Volume: 22
Issue: 1
Pages: 92
•
•
•
•
•
Publication
28368402 | J:247888
First Author: Cesarini V
Year: 2017
Journal: Oncogene
Title: Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo.
Volume: 36
Issue: 31
Pages: 4508-4515
•
•
•
•
•
Publication
21278735 | J:169306
First Author: Biton M
Year: 2011
Journal: Nat Immunol
Title: Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk.
Volume: 12
Issue: 3
Pages: 239-46
•
•
•
•
•
Publication
26818109 | J:231632
First Author: Jolly LA
Year: 2016
Journal: Cancer Res
Title: Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss.
Volume: 76
Issue: 7
Pages: 1804-13
•
•
•
•
•
Publication
24291004 | J:206975
First Author: Piovan E
Year: 2013
Journal: Cancer Cell
Title: Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia.
Volume: 24
Issue: 6
Pages: 766-76
•
•
•
•
•
Publication
21575859 | J:172424
First Author: Carver BS
Year: 2011
Journal: Cancer Cell
Title: Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer.
Volume: 19
Issue: 5
Pages: 575-86
•
•
•
•
•
Publication
31331961 | J:278688
 
First Author: Jezek J
Year: 2019
Journal: J Cell Sci
Title: Synergistic repression of thyroid hyperplasia by cyclin C and Pten.
Volume: 132
Issue: 16
•
•
•
•
•
Publication
30914431 | J:276351
First Author: Shurin GV
Year: 2019
Journal: Cancer Res
Title: Melanoma-Induced Reprogramming of Schwann Cell Signaling Aids Tumor Growth.
Volume: 79
Issue: 10
Pages: 2736-2747
•
•
•
•
•
Publication
25472943 | J:221978
First Author: Deuker MM
Year: 2015
Journal: Cancer Discov
Title: PI3'-kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAF-mutated melanoma.
Volume: 5
Issue: 2
Pages: 143-53
•
•
•
•
•
Publication
32782145 | J:304228
First Author: Li XX
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific Pten inactivation reveals essential role of the sympathetic nervous system activity in adipose tissue development.
Volume: 531
Issue: 2
Pages: 118-124
•
•
•
•
•
Publication
28433543 | J:243339
First Author: Kim SH
Year: 2017
Journal: J Invest Dermatol
Title: Phenformin Inhibits Myeloid-Derived Suppressor Cells and Enhances the Anti-Tumor Activity of PD-1 Blockade in Melanoma.
Volume: 137
Issue: 8
Pages: 1740-1748
•
•
•
•
•
Publication
33690225 | J:306045
 
First Author: Huang F
Year: 2021
Journal: J Clin Invest
Title: Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses.
Volume: 131
Issue: 8
•
•
•
•
•
Publication
26390244 | J:228904
First Author: Herranz D
Year: 2015
Journal: Nat Med
Title: Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.
Volume: 21
Issue: 10
Pages: 1182-9
•
•
•
•
•
Publication
23319880 | J:195067
 
First Author: Keng VW
Year: 2012
Journal: Sarcoma
Title: Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.
Volume: 2012
Pages: 620834
•
•
•
•
•
Publication
30662519 | J:307277
First Author: Lui JW
Year: 2019
Journal: J Cancer
Title: The Efficiency of Verteporfin as a Therapeutic Option in Pre-Clinical Models of Melanoma.
Volume: 10
Issue: 1
Pages: 1-10
•
•
•
•
•
Publication
31375534 | J:289994
First Author: Etzerodt A
Year: 2019
Journal: J Exp Med
Title: Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.
Volume: 216
Issue: 10
Pages: 2394-2411
•
•
•
•
•
Publication
24746818 | J:277956
First Author: Luo X
Year: 2014
Journal: Cell Rep
Title: Isolation and molecular characterization of circulating melanoma cells.
Volume: 7
Issue: 3
Pages: 645-53
•
•
•
•
•
Publication
33953176 | J:306090
First Author: Di Leo L
Year: 2021
Journal: Nat Commun
Title: Loss of Ambra1 promotes melanoma growth and invasion.
Volume: 12
Issue: 1
Pages: 2550
•
•
•
•
•
Publication
36332622 | J:332355
First Author: Han M
Year: 2022
Journal: Cancer Cell
Title: FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine prostate cancer.
Volume: 40
Issue: 11
Pages: 1306-1323.e8
•
•
•
•
•
Publication
24736544 | J:212454
First Author: Ho PC
Year: 2014
Journal: Cancer Res
Title: Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.
Volume: 74
Issue: 12
Pages: 3205-17
•
•
•
•
•
Publication
28986383 | J:249341
First Author: Brady DC
Year: 2017
Journal: Cancer Res
Title: Copper Chelation Inhibits BRAFV600E-Driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors.
Volume: 77
Issue: 22
Pages: 6240-6252
•
•
•
•
•
Publication
18199538 | J:131418
First Author: Yeager N
Year: 2008
Journal: Cancer Res
Title: Mammalian target of rapamycin is the key effector of phosphatidylinositol-3-OH-initiated proliferative signals in the thyroid follicular epithelium.
Volume: 68
Issue: 2
Pages: 444-9
•
•
•
•
•
Publication
31122699 | J:291195
First Author: Zhang SJ
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific PTEN and EGFR dysfunctions affect neuromuscular junction development by impairing Agrin signaling and autophagy.
Volume: 515
Issue: 1
Pages: 50-56
•
•
•
•
•
Publication
30824837 | J:285318
First Author: Long JE
Year: 2019
Journal: Cell Death Differ
Title: Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation.
Volume: 26
Issue: 11
Pages: 2416-2429
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Tg(Pbsn-cre)8113ANg/?
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pik3cd/Pik3cd Pten/Pten Cd19/Cd19<+>
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Eif4e/Eif4e Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Tg(TPO-cre)1Shk/?
Background: 129S1.Cg-Pten Tg(TPO-cre)1Shk
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cdkn1b/Cdkn1b Pten/Pten Tg(TPO-cre)1Shk/?
Background: 129S1.Cg-Cdkn1b Tg(TPO-cre)1Shk Pten
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cdkn1b/Cdkn1b<+> Pten/Pten Tg(TPO-cre)1Shk/?
Background: 129S1.Cg-Cdkn1b Tg(TPO-cre)1Shk Pten
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Tnfrsf4/Tnfrsf4<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Tg(GFAP-TAg121)1Tvd/?
Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * DBA/2 * FVB/N
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten
Background: involves: 129S1/Sv
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten<+> Spry1/Spry1 Spry2/Spry2 Tg(Osr1-cre)4Mrt/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Tg(Osr1-cre)4Mrt/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Tg(Cnp-EGFR)10Nrat/? Tg(Dhh-cre)1Mejr/?
Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten<+> Tg(Cnp-EGFR)10Nrat/? Tg(Dhh-cre)1Mejr/?
Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Tg(Dhh-cre)1Mejr/?
Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Trp53/Trp53 Tg(TPO-cre)1Shk/?
Background: 129.Cg-Tg(TPO-cre)1Shk Trp53 Pten
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Kras/Kras<+> Pten/Pten Tg(TPO-cre)1Shk/?
Background: 129.Cg-Kras Tg(Tpo-cre)1Shk Pten
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Braf/Braf<+> Pten/Pten Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pten/Pten Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S1/Sv * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Braf/Braf<+> Pten/Pten<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
8041720 | J:91409
First Author: Kim SH
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice.
Volume: 91
Issue: 15
Pages: 6914-8
•
•
•
•
•
Protein Coding Gene
MGI:88190 | Braf
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
HT Experiment
GSE74960 | Role of the histone demethylase KDM2B in hematopoietic homeostasis and malignancies [Kras background mouse gene expression]
Series Id: E-GEOD-74960
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
Publication
19174523 | J:146290
First Author: Klinakis A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Igf1r as a therapeutic target in a mouse model of basal-like breast cancer.
Volume: 106
Issue: 7
Pages: 2359-64
•
•
•
•
•
Publication
8227147 | J:96717
First Author: Kim SH
Year: 1993
Journal: J Cell Biol
Title: Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia.
Volume: 123
Issue: 4
Pages: 877-93
•
•
•
•
•
Allele
Kras<tm1Bbd> | MGI:3582830
 
Name: Kirsten rat sarcoma viral oncogene homolog; targeted mutation 1, Mariano Barbacid
Allele Type: Targeted
•
•
•
•
•
Allele
Kras<tm5Tyj> | MGI:3813896
Name: Kirsten rat sarcoma viral oncogene homolog; targeted mutation 5, Tyler Jacks
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Strain
MGI:3813920 | B6;129-Kras<tm5Tyj>/J
Attribute String: mutant stock, targeted mutation
•
•
•
•
•
Strain
MGI:5505639 | B6(Cg)-Kras<tm5Tyj>/J
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom