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Search results 101 to 183 out of 183 for Fgb

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1620420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4840018
Age: embryonic day 12.5
Note: There is fibrin deposition in this mutant.
Specimen Label: Not shown
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:6449861
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-14
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:2823927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6450008
Age: postnatal newborn
Note: Some traces of fibrin deposition were evident in the glomeruli and tubuli.
Specimen Label: not shown
Detected: true
Specimen Num: 11
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693254
Age: postnatal adult
Image: UC Davis_1882044
Specimen Label: UC Davis_1882044
Detected: true
Specimen Num: 15
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•
GXD Expression
GXD Expression
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1668825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4840018
Age: embryonic day 17.5
Image: 1i
Note: There is fibrin deposition.
Specimen Label: 1i
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1668825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4840018
Age: embryonic day 17.5
Note: There is fibrin deposition in this mutant.
Specimen Label: Not shown FVII+/+/PC-/-
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1668825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4840018
Age: embryonic day 17.5
Note: There is fibrin deposition in this mutant.
Specimen Label: Not shown FVII+/-/PC-/-
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668825
Stage: TS25
Assay Id: MGI:4840018
Age: embryonic day 17.5
Note: There are no fibrin deposits in wild type embryos.
Specimen Label: Not shown wild type
Detected: false
Specimen Num: 6
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•
GXD Expression
GXD Expression
   
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668825
Stage: TS25
Assay Id: MGI:4840018
Age: embryonic day 17.5
Note: There are no fibrin deposits in this mutant embryo.
Specimen Label: Not shown FVII-/-/PC-+/+
Detected: false
Specimen Num: 7
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•
GXD Expression
GXD Expression
 
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4840018
Age: embryonic day 12.5
Note: Fibrin deposits are in the neural canal.
Specimen Label: Not shown
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4840018
Age: embryonic day 12.5
Image: 3a
Specimen Label: 3a
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
 
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4840018
Age: embryonic day 17.5
Note: There is fibrin deposition in this mutant.
Specimen Label: Not shown FVII+/+/PC-/-
Detected: true
Specimen Num: 4
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4840018
Age: embryonic day 17.5
Note: There is fibrin deposition in this mutant.
Specimen Label: Not shown FVII+/-/PC-/-
Detected: true
Specimen Num: 5
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:4840018
Age: embryonic day 17.5
Note: There are no fibrin deposits in wild type embryos.
Specimen Label: Not shown wild type
Detected: false
Specimen Num: 6
•
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•
GXD Expression
GXD Expression
   
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:4840018
Age: embryonic day 17.5
Note: There are no fibrin deposits in this mutant embryo.
Specimen Label: Not shown FVII-/-/PC-+/+
Detected: false
Specimen Num: 7
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4839927
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4840018
Age: embryonic day 14.5
Note: Fibron deposition in the brain is less than in the liver.
Specimen Label: Not shown FVII+/-/PC-/-
Detected: true
Specimen Num: 9
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•
GXD Expression
GXD Expression
 
Probe: MGI:6449861
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-14
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:2778227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6450008
Age: postnatal newborn
Note: Some traces of fibrin deposition were evident in the glomeruli and tubuli.
Specimen Label: not shown
Detected: true
Specimen Num: 11
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Publication
- | J:43900
   
First Author: Chung DW
Year: 1995
Title: Chapter 105. Hereditary disorders of fibrinogen and factor XIII
Volume: III
Pages: 3223-3240
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Publication
12750384 | J:84884
First Author: Sakao E
Year: 2003
Journal: J Biol Chem
Title: Two-peaked synchronization in day/night expression rhythms of the fibrinogen gene cluster in the mouse liver.
Volume: 278
Issue: 33
Pages: 30450-7
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Publication
11018075 | J:65092
First Author: Ishiguro K
Year: 2000
Journal: J Clin Invest
Title: Complete antithrombin deficiency in mice results in embryonic lethality.
Volume: 106
Issue: 7
Pages: 873-8
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Publication
10829076 | J:62716
First Author: Yin ZF
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Prothrombotic phenotype of protein Z deficiency.
Volume: 97
Issue: 12
Pages: 6734-8
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Publication
9819035 | J:51137
 
First Author: Broze GJ Jr
Year: 1998
Journal: Blood Coagul Fibrinolysis
Title: Tissue factor pathway inhibitor gene disruption.
Volume: 9 Suppl 1
Pages: S89-92
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Publication
9788960 | J:50527
First Author: Jalbert LR
Year: 1998
Journal: J Clin Invest
Title: Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice.
Volume: 102
Issue: 8
Pages: 1481-8
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Publication
12218060 | J:80043
First Author: Gu JM
Year: 2002
Journal: J Biol Chem
Title: Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality.
Volume: 277
Issue: 45
Pages: 43335-43
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Publication
15914557 | J:118491
First Author: Tolhurst G
Year: 2005
Journal: Blood
Title: Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling.
Volume: 106
Issue: 5
Pages: 1644-51
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Publication
11891199 | J:75302
First Author: Iwaki T
Year: 2002
Journal: Am J Pathol
Title: Fibrinogen stabilizes placental-maternal attachment during embryonic development in the mouse.
Volume: 160
Issue: 3
Pages: 1021-34
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Publication
9384381 | J:44294
First Author: Rosen ED
Year: 1997
Journal: Nature
Title: Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.
Volume: 390
Issue: 6657
Pages: 290-4
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Publication
10749569 | J:61481
First Author: Chan JC
Year: 2000
Journal: J Clin Invest
Title: Combined factor VII/protein C deficiency results in intrauterine coagulopathy in mice.
Volume: 105
Issue: 7
Pages: 897-903
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Publication
16824188 | J:129287
First Author: Yang H
Year: 2006
Journal: J Thromb Haemost
Title: Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo.
Volume: 4
Issue: 10
Pages: 2230-7
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Publication
7613034 | J:24378
First Author: Mills KA
Year: 1995
Journal: Mamm Genome
Title: Genetic mapping near the myd locus on mouse chromosome 8.
Volume: 6
Issue: 4
Pages: 278-80
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Publication
20152176 | J:157920
First Author: Zovein AC
Year: 2010
Journal: Dev Cell
Title: Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism.
Volume: 18
Issue: 1
Pages: 39-51
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Publication
27140400 | J:237076
First Author: Crosswhite PL
Year: 2016
Journal: J Clin Invest
Title: CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity.
Volume: 126
Issue: 6
Pages: 2254-66
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Publication
11159184 | J:67398
First Author: Chan JC
Year: 2001
Journal: Am J Pathol
Title: The characterization of mice with a targeted combined deficiency of protein c and factor XI.
Volume: 158
Issue: 2
Pages: 469-79
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Publication
21305474 | J:170493
First Author: Pfister S
Year: 2011
Journal: Int J Dev Biol
Title: Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos.
Volume: 55
Issue: 1
Pages: 45-58
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Publication
16707424 | J:109061
First Author: Fenske TS
Year: 2006
Journal: Cancer Res
Title: Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice.
Volume: 66
Issue: 10
Pages: 5029-38
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Publication
16452087 | J:263376
First Author: Trinidad JC
Year: 2006
Journal: Mol Cell Proteomics
Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
Volume: 5
Issue: 5
Pages: 914-22
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Publication
30571485 | J:295059
First Author: Patel MM
Year: 2018
Journal: J Am Heart Assoc
Title: Role of ADTRP (Androgen-Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function.
Volume: 7
Issue: 22
Pages: e010690
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Publication
36920550 | J:336100
First Author: Brütsch SM
Year: 2023
Journal: Cell Mol Life Sci
Title: Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome.
Volume: 80
Issue: 4
Pages: 89
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Publication
28071719 | J:265607
 
First Author: Naba A
Year: 2017
Journal: Sci Rep
Title: Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Volume: 7
Pages: 40495
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Publication
22159717 | J:265604
First Author: Naba A
Year: 2012
Journal: Mol Cell Proteomics
Title: The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Volume: 11
Issue: 4
Pages: M111.014647
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
9883527 | J:51865
First Author: Archibald AL
Year: 1998
Journal: Anim Genet
Title: RFLP and linkage analysis of the porcine fibrinogen loci--FGA, FGB and FGG.
Volume: 29
Issue: 6
Pages: 471-2
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Allele
Fgb<em1Smoc> | MGI:7289673
Name: fibrinogen beta chain; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
4472824 | -
First Author: Kay AB
Year: 1974
Journal: Br J Haematol
Title: The identification of fibrinopeptide B as a chemotactic agent derived from human fibrinogen.
Volume: 27
Issue: 4
Pages: 669-77
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Publication
10666208 | -
First Author: Duga S
Year: 2000
Journal: Blood
Title: Missense mutations in the human beta fibrinogen gene cause congenital afibrinogenemia by impairing fibrinogen secretion.
Volume: 95
Issue: 4
Pages: 1336-41
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Publication
1634610 | -
First Author: Koopman J
Year: 1992
Journal: J Clin Invest
Title: Molecular basis of fibrinogen Naples associated with defective thrombin binding and thrombophilia. Homozygous substitution of B beta 68 Ala----Thr.
Volume: 90
Issue: 1
Pages: 238-44
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Protein Domain
IPR037580 | Fibrinogen_beta
Type: Family
Description: Fibrinogens are cleaved by thrombin to yield fibrins, which polymerize to form the insoluble fibrin clot which blocks sites of vascular injury, preventing further blood loss. The clot is subsequently degraded by plasmin (fibrinolysis) []. There are three fibrinogens, alpha, beta and gamma []. Thrombin activates fibrinogen to release a fibrinopeptide []. The newly exposed N terminus forms an Glu-Lys isopeptide bond, which is stabilized by factor XIIIA []. Fibrinogen is also required for successful pregnancy, and in knockout mice fatal uterine bleeding occurs around the tenth day of gestation [].This entry represents the beta chain of fibrinogen (FGB). Cleavage by thrombin releases fibrinopeptidase B, a chemotactic agent []. Mutations in the FGB gene can lead to congenital afibrinogenemia, which can cause a hemphilia [], or congenital dysfibrinogenemia, frequently asymptomatic [].
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Publication
7649481 | J:28436
First Author: Suh TT
Year: 1995
Journal: Genes Dev
Title: Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice.
Volume: 9
Issue: 16
Pages: 2020-33
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Publication
155369 | -
 
First Author: Lebedeva IV
Year: 1979
Journal: Zdravookhr Ross Fed
Title: [Economic effectiveness of dispensary care in textile enterprises].
Issue: 4
Pages: 14-6
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Publication
2404012 | -
First Author: Lord ST
Year: 1990
Journal: J Biol Chem
Title: Analysis of fibrinogen A alpha-fusion proteins. Mutants which inhibit thrombin equivalently are not equally good substrates.
Volume: 265
Issue: 2
Pages: 838-43
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Publication
2143188 | -
First Author: Kirschbaum NE
Year: 1990
Journal: J Biol Chem
Title: A unique proteolytic fragment of human fibrinogen containing the A alpha COOH-terminal domain of the native molecule.
Volume: 265
Issue: 23
Pages: 13669-76
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Protein
Q8K0E8
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
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Protein
Q3TGR2
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
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