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Search results 101 to 185 out of 185 for Laptm5

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:2681809
Assay Type: Northern blot
Annotation Date: 2003-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610518
Stage: TS18
Assay Id: MGI:2681813
Age: embryonic day 11.0
Specimen Label: Heart
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2681809
Assay Type: Northern blot
Annotation Date: 2003-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185818
Stage: TS18
Assay Id: MGI:2681813
Age: embryonic day 11.0
Specimen Label: Head
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2681809
Assay Type: Northern blot
Annotation Date: 2003-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684618
Stage: TS18
Assay Id: MGI:2681813
Age: embryonic day 11.0
Specimen Label: Liver
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2681809
Assay Type: Northern blot
Annotation Date: 2003-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185718
Stage: TS18
Assay Id: MGI:2681813
Age: embryonic day 11.0
Specimen Label: Body
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6444324
Assay Type: RT-PCR
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6445530
Age: postnatal week 5
Specimen Label: wild type control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6444324
Assay Type: RT-PCR
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6445530
Age: postnatal week 5
Specimen Label: miR-183C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7779674
Assay Type: RT-PCR
Annotation Date: 2024-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3800524
Stage: TS24
Assay Id: MGI:7779762
Age: embryonic day 16.0
Specimen Label: M
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7779674
Assay Type: RT-PCR
Annotation Date: 2024-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914324
Stage: TS24
Assay Id: MGI:7779762
Age: embryonic day 16.0
Specimen Label: AC
Detected: true
Specimen Num: 2
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Publication
8661146 | J:34144
First Author: Adra CN
Year: 1996
Journal: Genomics
Title: LAPTM5: a novel lysosomal-associated multispanning membrane protein preferentially expressed in hematopoietic cells.
Volume: 35
Issue: 2
Pages: 328-37
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Publication
8839844 | J:35784
First Author: Scott LM
Year: 1996
Journal: Blood
Title: E3, a hematopoietic-specific transcript directly regulated by the retinoic acid receptor alpha.
Volume: 88
Issue: 7
Pages: 2517-30
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Publication
18562292 | J:137202
First Author: Fouladkou F
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization.
Volume: 105
Issue: 25
Pages: 8585-90
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Publication
24108661 | J:356581
First Author: Pazin DE
Year: 2014
Journal: J Orthop Res
Title: Gene signature of the embryonic meniscus.
Volume: 32
Issue: 1
Pages: 46-53
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Publication
9611252 | J:48250
First Author: Iwama A
Year: 1998
Journal: Nucleic Acids Res
Title: Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.
Volume: 26
Issue: 12
Pages: 3034-43
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Publication
21308776 | J:233118
First Author: Abdallah BM
Year: 2011
Journal: J Bone Miner Res
Title: DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Volume: 26
Issue: 7
Pages: 1457-71
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Publication
20439489 | J:163558
First Author: Tarantino C
Year: 2010
Journal: FASEB J
Title: miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells.
Volume: 24
Issue: 9
Pages: 3255-63
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Publication
23341629 | J:193822
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
17116753 | -
First Author: Pak Y
Year: 2006
Journal: J Cell Biol
Title: Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination.
Volume: 175
Issue: 4
Pages: 631-45
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Allele
Laptm5<em2Smoc> | MGI:7290782
Name: lysosomal-associated protein transmembrane 5; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6475671 | C57BL/6JSmoc-Laptm5<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Laptm5<em1Smoc> | MGI:7290781
Name: lysosomal-associated protein transmembrane 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6475670 | C57BL/6JSmoc-Laptm5<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR018397 | Lysosomal-assoc_TM_prot5
Type: Family
Description: The lysosome associated protein transmembrane (LAPTM) family is comprised of three members: LAPTM5, LAPTM4a and LAPTM4b; they are lysosome-associated transmembrane proteins, found in mammals, insects and nematodes.This entry represents LAPTM5, which is a lysosomal protein expressed in cells of lymphoid and myeloid origin. LAPTM5 trafficking from the Golgi to the lysosome requires its association with the ubiquitin ligase Nedd4 and the clathrin adaptor GGA3 []. LAPTM5 negatively regulates T and B cell receptor signaling by directly interacting with these receptors and mediating their down-regulation [, ]. It is also a positive regulator of NF-kB and MAPK signaling allowing efficient proinflammatory cytokine production in response to macrophage activation [].
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Protein
Q3U2D0
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
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Protein
B1ASF7
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: true
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Publication
11980562 | -
First Author: Hogue DL
Year: 2002
Journal: Biochem J
Title: Lysosome-associated protein transmembrane 4 alpha (LAPTM4 alpha) requires two tandemly arranged tyrosine-based signals for sorting to lysosomes.
Volume: 365
Issue: Pt 3
Pages: 721-30
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Publication
10519401 | -
First Author: Cabrita MA
Year: 1999
Journal: Cancer Res
Title: Mouse transporter protein, a membrane protein that regulates cellular multidrug resistance, is localized to lysosomes.
Volume: 59
Issue: 19
Pages: 4890-7
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Publication
19787053 | -
First Author: Inoue J
Year: 2009
Journal: PLoS One
Title: Lysosomal-associated protein multispanning transmembrane 5 gene (LAPTM5) is associated with spontaneous regression of neuroblastomas.
Volume: 4
Issue: 9
Pages: e7099
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Protein Domain
IPR018396 | LAPTM_4A/5
Type: Family
Description: The lysosome associated protein transmembrane (LAPTM) family is comprised of three members: LAPTM5, LAPTM4a and LAPTM4b; they are lysosome-associated transmembrane proteins, found in mammals, insects and nematodes.This entry represents LAPTM4 alpha (LAPTM4A) and LAPTM45. LAPTM4A regulates the intracellular compartmentalisation of amphipathic solutes and possibly the sensitivity of cells toward anthracyclines, antibiotics, ionophores, nucleobases and organic cations [, ]. LAPTM5 may have functional role during embryogenesis and in adult hematopoietic cells [].
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Protein
Q61168
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q3UD11
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q3TBF2
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q8BFZ0
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q544S4
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q3TBE8
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q3TD09
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: false
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Protein
Q6A0D3
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: true
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Protein
Q3TAZ4
Organism: Mus musculus/domesticus
Length: 231  
Fragment?: false
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Protein
Q3T982
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: true
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Protein
F6WX18
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: true
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Protein
Q3TBQ5
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q3TC76
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
F8WH95
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: true
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Protein
Q3U6X9
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q3TBK6
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q60961
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: false
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Protein
Q8BG66
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: false
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Protein
E9QLR3
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
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Protein
Q9CRX2
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
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Publication
29038051 | J:255655
First Author: Nam KN
Year: 2018
Journal: Biochim Biophys Acta
Title: Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice.
Volume: 1864
Issue: 1
Pages: 152-161
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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