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Search results 401 to 500 out of 529 for Aqp3

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Type Details Score
Publication
21178974 | J:186879
First Author: Gaeggeler HP
Year: 2011
Journal: Kidney Int
Title: Vasopressin-dependent coupling between sodium transport and water flow in a mouse cortical collecting duct cell line.
Volume: 79
Issue: 8
Pages: 843-52
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Publication
17377981 | J:120884
First Author: Varadaraj K
Year: 2007
Journal: Dev Dyn
Title: Functional expression of aquaporins in embryonic, postnatal, and adult mouse lenses.
Volume: 236
Issue: 5
Pages: 1319-28
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Publication
16079275 | J:100191
First Author: Verkman AS
Year: 2005
Journal: J Cell Sci
Title: More than just water channels: unexpected cellular roles of aquaporins.
Volume: 118
Issue: Pt 15
Pages: 3225-32
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Publication
20121927 | J:160026
First Author: Larsen HS
Year: 2009
Journal: Eur J Oral Sci
Title: Aquaporin expression patterns in the developing mouse salivary gland.
Volume: 117
Issue: 6
Pages: 655-62
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Publication
28384265 | J:245619
First Author: Darrah R
Year: 2017
Journal: PLoS One
Title: Growth deficits in cystic fibrosis mice begin in utero prior to IGF-1 reduction.
Volume: 12
Issue: 4
Pages: e0175467
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Publication
15550389 | J:95502
First Author: Qian CN
Year: 2005
Journal: J Biol Chem
Title: Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium.
Volume: 280
Issue: 5
Pages: 3938-45
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Publication
9757370 | J:52315
First Author: Knoers NV
Year: 1998
Journal: Curr Opin Pediatr
Title: Aquaporin molecular biology and clinical abnormalities of the water transport channels.
Volume: 10
Issue: 4
Pages: 428-34
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Publication
10232700 | J:56223
First Author: Verkman AS
Year: 1999
Journal: J Am Soc Nephrol
Title: Lessons on renal physiology from transgenic mice lacking aquaporin water channels.
Volume: 10
Issue: 5
Pages: 1126-35
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Publication
24904084 | J:316110
First Author: Guo Q
Year: 2015
Journal: J Am Soc Nephrol
Title: Adam10 mediates the choice between principal cells and intercalated cells in the kidney.
Volume: 26
Issue: 1
Pages: 149-59
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Publication
11066060 | J:65472
First Author: Offenberg H
Year: 2000
Journal: Mol Reprod Dev
Title: mRNAs encoding aquaporins are present during murine preimplantation development.
Volume: 57
Issue: 4
Pages: 323-30
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Publication
10788316 | J:63371
First Author: Edashige K
Year: 2000
Journal: Cryobiology
Title: Expression of mRNAs of the aquaporin family in mouse oocytes and embryos.
Volume: 40
Issue: 2
Pages: 171-5
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Publication
12031518 | J:80146
First Author: Huang D
Year: 2002
Journal: Hear Res
Title: Expression patterns of aquaporins in the inner ear: evidence for concerted actions of multiple types of aquaporins to facilitate water transport in the cochlea.
Volume: 165
Issue: 1-2
Pages: 85-95
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Publication
22479204 | J:183847
First Author: Bedzhov I
Year: 2012
Journal: PLoS Genet
Title: Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin.
Volume: 8
Issue: 3
Pages: e1002609
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Publication
29357412 | J:283152
First Author: Boivin FJ
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: β-Catenin in stromal progenitors controls medullary stromal development.
Volume: 314
Issue: 6
Pages: F1177-F1187
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Publication
26847765 | J:250201
 
First Author: Tanahashi H
Year: 2016
Journal: Sci Rep
Title: Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.
Volume: 6
Pages: 20241
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Publication
18172001 | J:132020
First Author: Makita R
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.
Volume: 294
Issue: 3
Pages: F542-53
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Publication
18177851 | J:131012
First Author: Marose TD
Year: 2008
Journal: Dev Biol
Title: Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.
Volume: 314
Issue: 1
Pages: 112-26
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Publication
29237740 | J:292950
First Author: Hinze C
Year: 2018
Journal: J Am Soc Nephrol
Title: GRHL2 Is Required for Collecting Duct Epithelial Barrier Function and Renal Osmoregulation.
Volume: 29
Issue: 3
Pages: 857-868
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Publication
20487527 | J:161404
 
First Author: Stevens J
Year: 2010
Journal: BMC Dev Biol
Title: Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow.
Volume: 10
Pages: 54
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Publication
20364088 | J:161480
First Author: Mellitzer G
Year: 2010
Journal: J Clin Invest
Title: Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival.
Volume: 120
Issue: 5
Pages: 1708-21
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Publication
16973757 | J:115933
First Author: Suh JM
Year: 2006
Journal: Mol Endocrinol
Title: The expression profiles of nuclear receptors in the developing and adult kidney.
Volume: 20
Issue: 12
Pages: 3412-20
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Publication
19367412 | J:151683
First Author: Parreira KS
Year: 2009
Journal: Pflugers Arch
Title: Expression patterns of the aquaporin gene family during renal development: influence of genetic variability.
Volume: 458
Issue: 4
Pages: 745-59
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Publication
36343245 | J:332093
First Author: Szeto IYY
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.
Volume: 119
Issue: 46
Pages: e2122121119
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Publication
27362799 | J:307439
First Author: Chen SR
Year: 2016
Journal: Cell Death Dis
Title: Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.
Volume: 7
Issue: 6
Pages: e2281
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Publication
25803581 | J:232968
First Author: Boivin FJ
Year: 2015
Journal: PLoS One
Title: Stromally expressed β-catenin modulates Wnt9b signaling in the ureteric epithelium.
Volume: 10
Issue: 3
Pages: e0120347
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Publication
19855135 | J:154589
First Author: Jeong HW
Year: 2009
Journal: J Clin Invest
Title: Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice.
Volume: 119
Issue: 11
Pages: 3290-300
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Publication
32857879 | J:332131
First Author: Perera SN
Year: 2020
Journal: Glia
Title: Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach.
Volume: 68
Issue: 12
Pages: 2550-2584
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
27059301 | J:233702
First Author: Su Z
Year: 2016
Journal: FEBS Lett
Title: LncRNA H19 functions as a competing endogenous RNA to regulate AQP3 expression by sponging miR-874 in the intestinal barrier.
Volume: 590
Issue: 9
Pages: 1354-64
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Publication
22397925 | J:185468
First Author: Nilsson L
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Disruption of cyclooxygenase-2 prevents downregulation of cortical AQP2 and AQP3 in response to bilateral ureteral obstruction in the mouse.
Volume: 302
Issue: 11
Pages: F1430-9
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Publication
12239222 | -
First Author: Roudier N
Year: 2002
Journal: J Biol Chem
Title: AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL.
Volume: 277
Issue: 48
Pages: 45854-9
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Allele
Aqp3<em1Smoc> | MGI:7288314
Name: aquaporin 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6474787 | C57BL/6-Aqp3<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Aqp3<tm1Ask> | MGI:2150021
Name: aquaporin 3; targeted mutation 1, Alan S Verkman
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Aqp3/Aqp3
Background: involves: C57BL/6J * CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aqp3/Aqp3
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aqp3/Aqp3 Aqp4/Aqp4
Background: involves: C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aqp3/Aqp3 Aqp4/Aqp4
Background: involves: C57BL/6J * CD-1
Zygosity: cx
Has Mutant Allele: true
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Publication
7517548 | -
First Author: Ishibashi K
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells.
Volume: 91
Issue: 14
Pages: 6269-73
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Protein Domain
IPR023275 | Aquaporin_3
Type: Family
Description: Aquaporins are water channels, present in both higher and lower organisms, that belong to the major intrinsic protein family. Most aquaporins are highly selective for water, though some also facilitate the movement of small uncharged molecules such as glycerol []. In higher eukaryotes these proteins play diverse roles in the maintenance of water homeostasis, indicating that membrane water permeability can be regulated independently of solute permeability. In microorganisms however, many of which do not contain aquaporins, they do not appear to play such a broad role. Instead, they assist specific microbial lifestyles within the environment, e.g. they confer protection against freeze-thaw stress and may help maintain water permeability at low temperatures []. The regulation of aquaporins is complex, including transcriptional, post-translational, protein-trafficking and channel-gating mechanisms that are frequently distinct for each family member.Structural studies show that aquaporins are present in the membrane as tetramers, though each monomer contains its own channel [, , ]. The monomer has an overall "hourglass"structure made up of three structural elements: an external vestibule, an internal vestibule, and an extended pore which connects the two vestibules. Substrate selectivity is conferred by two mechanisms. Firstly, the diameter of the pore physically limits the size of molecules that can pass through the channel. Secondly, specific amino acids within the molecule regulate the preference for hydrophobic or hydrophilic substrates.Aquaporins are classified into two subgroups: the aquaporins (also known as orthodox aquaporins), which transport only water, and the aquaglyceroporins, which transport glycerol, urea, and other small solutes in addition to water [, ].Aquaporin-3 (AQP3) forms a water-specific channel that renders the kidney medullary collecting duct highly permeability to water. It may function as a water and urea exit mechanism in antidiuresis in collecting duct cells, and is also slightly permeable to urea and glycerol. It may also play an important role in gastrointestinal tract water transport and in glycerol metabolism. It is widely expressed in epithelial cells of kidney (collecting ducts []) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Expression studies have shown that cells transfected with AQP3 cDNA react strongly with anti-GIL antibodies []. These studies hence report the first cases of human AQP3 deficiency and offer the molecular basis of a new blood group system, GIL, believed to be encoded by AQP3 [].
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Publication
26837049 | J:233327
First Author: Watanabe S
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells.
Volume: 471
Issue: 1
Pages: 191-7
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HT Experiment
GSE131196 | SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE139587 | SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms (scRNA-seq: batch2)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
9806845 | J:51114
First Author: Koyama N
Year: 1998
Journal: Genomics
Title: Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene.
Volume: 54
Issue: 1
Pages: 169-72
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Publication
35086002 | J:323041
 
First Author: Zhang B
Year: 2022
Journal: Redox Biol
Title: Aquaporin-9 facilitates liver regeneration following hepatectomy.
Volume: 50
Pages: 102246
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Publication
17636116 | J:123305
First Author: Liu Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Aquaporin 9 is the major pathway for glycerol uptake by mouse erythrocytes, with implications for malarial virulence.
Volume: 104
Issue: 30
Pages: 12560-4
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Publication
9486146 | J:46296
First Author: Chou CL
Year: 1998
Journal: Am J Physiol
Title: Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice.
Volume: 274
Issue: 2 Pt 1
Pages: C549-54
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Publication
18241265 | J:169519
First Author: Mirza R
Year: 2008
Journal: Br J Dermatol
Title: Increased expression of aquaporin-3 in the epidermis of DHCR24 knockout mice.
Volume: 158
Issue: 4
Pages: 679-84
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Publication
24784577 | J:217140
First Author: Cano-Peñalver JL
Year: 2014
Journal: FASEB J
Title: Integrin-linked kinase regulates tubular aquaporin-2 content and intracellular location: a link between the extracellular matrix and water reabsorption.
Volume: 28
Issue: 8
Pages: 3645-59
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Publication
11773623 | J:130418
First Author: Nejsum LN
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Functional requirement of aquaporin-5 in plasma membranes of sweat glands.
Volume: 99
Issue: 1
Pages: 511-6
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Publication
26377795 | J:323064
First Author: Nam BY
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Double transduction of a Cre/LoxP lentiviral vector: a simple method to generate kidney cell-specific knockdown mice.
Volume: 309
Issue: 12
Pages: F1060-9
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