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Search results 101 to 108 out of 108 for Ykt6

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Type

Details

Score

Publication

20159557 | -

First Author:	Wen W
Year:	2010
Journal:	Mol Cell
Title:	Lipid-Induced conformational switch controls fusion activity of longin domain SNARE Ykt6.
Volume:	37
Issue:	3
Pages:	383-95

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Protein Domain

IPR045848 | R-SNARE_YKT6

Type:

Domain

Description:

YKT6 forms complexes with syntaxin-5 (Qa), GS28 (Qb) and either Bet1 (Qc) or GS15 (Qc). This complex regulates the early secretory pathway of eukaryotic cells at the level of the transport from the ER-Golgi intermediate compartment (ERGIC) to the cis-Golgi and transport from the trans-Golgi network to the cis-Golgi, respectively [, ]. YKT6 is a member of the R-SNARE subfamily of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins which contain coiled-coil helices (called SNARE motifs) that mediate the interactions between SNARE proteins, and a transmembrane domain.The SNARE complex mediates membrane fusion, important for trafficking of newly synthesized proteins, recycling of pre-existing proteins and organelle formation. SNARE proteins are classified into four groups, Qa-, Qb-, Qc- and R-SNAREs, depending on whether the residue in the hydrophilic centre layer of the four-helical bundle is a glutamine (Q) or arginine (R). Qa-, as well as Qb- and Qc-SNAREs, are localized to target organelle membranes, while R-SNARE is localized to vesicle membranes. They form unique complexes consisting of one member of each subgroup, that mediate fusion between a specific type of vesicles and their target organelle. Their SNARE motifs form twisted and parallel heterotetrameric helix bundles [].

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Publication

34559989 | J:325188

First Author:	Morrissey SM
Year:	2021
Journal:	Cell Metab
Title:	Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming.
Volume:	33
Issue:	10
Pages:	2040-2058.e10

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Publication

33274589 | J:319900

First Author:	Barz S
Year:	2020
Journal:	EMBO Rep
Title:	Atg1 kinase regulates autophagosome-vacuole fusion by controlling SNARE bundling.
Volume:	21
Issue:	12
Pages:	e51869

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Publication

9861047 | -

First Author:	Fasshauer D
Year:	1998
Journal:	Proc Natl Acad Sci U S A
Title:	Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs.
Volume:	95
Issue:	26
Pages:	15781-6

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Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

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Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

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Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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