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Search results 201 to 300 out of 537 for Rptor

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Category: Publication
Type Details Score
Publication
First Author: Xiao B
Year: 2020
Journal: Cell Rep
Title: Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR.
Volume: 31
Issue: 4
Pages: 107571
Publication
First Author: Haller S
Year: 2017
Journal: Cell Stem Cell
Title: mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance.
Volume: 21
Issue: 6
Pages: 806-818.e5
Publication
First Author: Hu S
Year: 2023
Journal: Hepatology
Title: Hepatocyte β-catenin loss is compensated by Insulin-mTORC1 activation to promote liver regeneration.
Volume: 77
Issue: 5
Pages: 1593-1611
Publication
First Author: Gan Z
Year: 2024
Journal: Sci Bull (Beijing)
Title: Excitatory amino acid transporter supports inflammatory macrophage responses.
Volume: 69
Issue: 15
Pages: 2405-2419
Publication
First Author: Tariq K
Year: 2022
Journal: Cell Rep
Title: Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss.
Volume: 41
Issue: 5
Pages: 111574
Publication
First Author: Yang W
Year: 2021
Journal: Dev Cell
Title: Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation.
Volume: 56
Issue: 6
Pages: 811-825.e6
Publication
First Author: Hu Y
Year: 2018
Journal: J Biol Chem
Title: Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways.
Volume: 293
Issue: 6
Pages: 2006-2014
Publication
First Author: Wiebe S
Year: 2023
Journal: Mol Brain
Title: Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP.
Volume: 16
Issue: 1
Pages: 9
Publication  
First Author: Blandino-Rosano M
Year: 2017
Journal: Nat Commun
Title: Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing.
Volume: 8
Pages: 16014
Publication
First Author: Iwata TN
Year: 2016
Journal: J Immunol
Title: Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.
Volume: 197
Issue: 6
Pages: 2250-60
Publication
First Author: Shin J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function.
Volume: 111
Issue: 8
Pages: E776-83
Publication
First Author: Tan H
Year: 2017
Journal: Immunity
Title: Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation.
Volume: 46
Issue: 3
Pages: 488-503
Publication
First Author: Xiao M
Year: 2017
Journal: Blood
Title: Osteoblasts support megakaryopoiesis through production of interleukin-9.
Volume: 129
Issue: 24
Pages: 3196-3209
Publication  
First Author: Huang B
Year: 2016
Journal: Nat Commun
Title: Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone.
Volume: 7
Pages: 13885
Publication  
First Author: Knight ZA
Year: 2014
Journal: Elife
Title: A critical role for mTORC1 in erythropoiesis and anemia.
Volume: 3
Pages: e01913
Publication
First Author: Jiang M
Year: 2017
Journal: J Cell Biochem
Title: mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis.
Volume: 118
Issue: 4
Pages: 748-753
Publication
First Author: Artinian J
Year: 2019
Journal: J Neurosci
Title: Regulation of Hippocampal Memory by mTORC1 in Somatostatin Interneurons.
Volume: 39
Issue: 43
Pages: 8439-8456
Publication
First Author: Quinn WJ 3rd
Year: 2017
Journal: J Clin Invest
Title: mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion.
Volume: 127
Issue: 11
Pages: 4207-4215
Publication
First Author: Jones DD
Year: 2016
Journal: J Clin Invest
Title: mTOR has distinct functions in generating versus sustaining humoral immunity.
Volume: 126
Issue: 11
Pages: 4250-4261
Publication
First Author: Asgarihafshejani A
Year: 2022
Journal: iScience
Title: Long-term potentiation at pyramidal cell to somatostatin interneuron synapses controls hippocampal network plasticity and memory.
Volume: 25
Issue: 5
Pages: 104259
Publication  
First Author: Canaud G
Year: 2019
Journal: Sci Transl Med
Title: Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair.
Volume: 11
Issue: 476
Publication
First Author: Peng H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells.
Volume: 495
Issue: 1
Pages: 1129-1135
Publication  
First Author: Pita-Thomas W
Year: 2019
Journal: Exp Neurol
Title: HDAC5 promotes optic nerve regeneration by activating the mTOR pathway.
Volume: 317
Pages: 271-283
Publication
First Author: Wang M
Year: 2017
Journal: Mol Cell Proteomics
Title: The Glial Cell-Derived Neurotrophic Factor (GDNF)-responsive Phosphoprotein Landscape Identifies Raptor Phosphorylation Required for Spermatogonial Progenitor Cell Proliferation.
Volume: 16
Issue: 6
Pages: 982-997
Publication
First Author: Deng D
Year: 2024
Journal: Bone Res
Title: Osteoclasts control endochondral ossification via regulating acetyl-CoA availability.
Volume: 12
Issue: 1
Pages: 49
Publication
First Author: Andrade ML
Year: 2021
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity.
Volume: 1866
Issue: 8
Pages: 158967
Publication
First Author: Li D
Year: 2016
Journal: FASEB J
Title: mTORC1 pathway disruption ameliorates brain inflammation following stroke via a shift in microglia phenotype from M1 type to M2 type.
Volume: 30
Issue: 10
Pages: 3388-3399
Publication
First Author: Reiling JH
Year: 2006
Journal: Oncogene
Title: Stress and mTORture signaling.
Volume: 25
Issue: 48
Pages: 6373-83
Publication
First Author: Saxton RA
Year: 2017
Journal: Cell
Title: mTOR Signaling in Growth, Metabolism, and Disease.
Volume: 168
Issue: 6
Pages: 960-976
Publication
First Author: Kakumoto K
Year: 2015
Journal: PLoS One
Title: mLST8 Promotes mTOR-Mediated Tumor Progression.
Volume: 10
Issue: 4
Pages: e0119015
Publication
First Author: Sato T
Year: 2009
Journal: J Biol Chem
Title: Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein.
Volume: 284
Issue: 19
Pages: 12783-91
Publication
First Author: Roberts DJ
Year: 2014
Journal: Mol Cell
Title: Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition.
Volume: 53
Issue: 4
Pages: 521-33
Publication
First Author: Gwinn DM
Year: 2008
Journal: Mol Cell
Title: AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Volume: 30
Issue: 2
Pages: 214-26
Publication
First Author: Inoki K
Year: 2011
Journal: J Clin Invest
Title: mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
Volume: 121
Issue: 6
Pages: 2181-96
Publication
First Author: Lai Y
Year: 2020
Journal: EMBO Rep
Title: DOCK5 regulates energy balance and hepatic insulin sensitivity by targeting mTORC1 signaling.
Volume: 21
Issue: 2
Pages: e49473
Publication
First Author: Karmaus PWF
Year: 2019
Journal: Nature
Title: Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.
Volume: 565
Issue: 7737
Pages: 101-105
Publication
First Author: Huynh H
Year: 2017
Journal: Cell Rep
Title: mTOR Inhibition Subdues Milk Disorder Caused by Maternal VLDLR Loss.
Volume: 19
Issue: 10
Pages: 2014-2025
Publication
First Author: Zhang X
Year: 2020
Journal: Nat Metab
Title: High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy.
Volume: 2
Issue: 1
Pages: 110-125
Publication  
First Author: Sutton LP
Year: 2015
Journal: Neuropharmacology
Title: Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine.
Volume: 99
Pages: 610-9
Publication
First Author: Ai D
Year: 2014
Journal: Circ Res
Title: Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis.
Volume: 114
Issue: 10
Pages: 1576-84
Publication
First Author: Everts B
Year: 2014
Journal: Nat Immunol
Title: TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
Volume: 15
Issue: 4
Pages: 323-32
Publication
First Author: Opejin A
Year: 2020
Journal: Cell Rep
Title: A Two-Step Process of Effector Programming Governs CD4(+) T Cell Fate Determination Induced by Antigenic Activation in the Steady State.
Volume: 33
Issue: 8
Pages: 108424
Publication
First Author: Do MH
Year: 2023
Journal: Immunity
Title: Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis.
Volume: 56
Issue: 11
Pages: 2555-2569.e5
Publication
First Author: Kogot-Levin A
Year: 2020
Journal: Cell Rep
Title: Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors.
Volume: 32
Issue: 4
Pages: 107954
Publication
First Author: Potter WB
Year: 2013
Journal: PLoS Biol
Title: Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling.
Volume: 11
Issue: 8
Pages: e1001627
Publication
First Author: Albert V
Year: 2015
Journal: Biochem Biophys Res Commun
Title: mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior.
Volume: 464
Issue: 2
Pages: 480-6
Publication
First Author: Han Y
Year: 2019
Journal: J Clin Invest
Title: Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation.
Volume: 129
Issue: 5
Pages: 1895-1909
Publication
First Author: Shi L
Year: 2019
Journal: PLoS Biol
Title: TSC1/mTOR-controlled metabolic-epigenetic cross talk underpins DC control of CD8+ T-cell homeostasis.
Volume: 17
Issue: 8
Pages: e3000420
Publication
First Author: Zhang Y
Year: 2017
Journal: J Bone Miner Res
Title: mTORC1 Inhibits NF-κB/NFATc1 Signaling and Prevents Osteoclast Precursor Differentiation, In Vitro and In Mice.
Volume: 32
Issue: 9
Pages: 1829-1840
Publication
First Author: Lee JH
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: SREBP-1a-stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1.
Volume: 115
Issue: 52
Pages: E12228-E12234
Publication
First Author: Li S
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Promoting axon regeneration in the adult CNS by modulation of the melanopsin/GPCR signaling.
Volume: 113
Issue: 7
Pages: 1937-42
Publication
First Author: Wang C
Year: 2016
Journal: Liver Int
Title: Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade.
Volume: 36
Issue: 8
Pages: 1176-86
Publication
First Author: Bridges CR
Year: 2017
Journal: Sci Rep
Title: USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors.
Volume: 7
Issue: 1
Pages: 391
Publication
First Author: Ni HM
Year: 2019
Journal: Hepatology
Title: Dual Roles of Mammalian Target of Rapamycin in Regulating Liver Injury and Tumorigenesis in Autophagy-Defective Mouse Liver.
Volume: 70
Issue: 6
Pages: 2142-2155
Publication
First Author: Linares JF
Year: 2013
Journal: Mol Cell
Title: K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells.
Volume: 51
Issue: 3
Pages: 283-96
Publication
First Author: Sengupta S
Year: 2010
Journal: Nature
Title: mTORC1 controls fasting-induced ketogenesis and its modulation by ageing.
Volume: 468
Issue: 7327
Pages: 1100-4
Publication
First Author: Gosis BS
Year: 2022
Journal: Science
Title: Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1.
Volume: 376
Issue: 6590
Pages: eabf8271
Publication
First Author: Wan M
Year: 2011
Journal: Cell Metab
Title: Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.
Volume: 14
Issue: 4
Pages: 516-27
Publication
First Author: Zhang H
Year: 2014
Journal: Curr Biol
Title: Somatic cells initiate primordial follicle activation and govern the development of dormant oocytes in mice.
Volume: 24
Issue: 21
Pages: 2501-8
Publication
First Author: Pollizzi KN
Year: 2015
Journal: PLoS One
Title: Cellular size as a means of tracking mTOR activity and cell fate of CD4+ T cells upon antigen recognition.
Volume: 10
Issue: 4
Pages: e0121710
Publication
First Author: Chen LC
Year: 2016
Journal: J Immunol
Title: A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells.
Volume: 197
Issue: 4
Pages: 1137-47
Publication
First Author: Zhang Y
Year: 2023
Journal: Cell Metab
Title: Dietary fructose-mediated adipocyte metabolism drives antitumor CD8(+) T cell responses.
Volume: 35
Issue: 12
Pages: 2107-2118.e6
Publication  
First Author: Yin N
Year: 2022
Journal: J Clin Invest
Title: SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation.
Volume: 132
Issue: 20
Publication
First Author: Wang C
Year: 2015
Journal: Hepatology
Title: 4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice.
Volume: 61
Issue: 1
Pages: 200-13
Publication
First Author: Feng P
Year: 2021
Journal: Theranostics
Title: The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis.
Volume: 11
Issue: 19
Pages: 9503-9518
Publication
First Author: Bork T
Year: 2020
Journal: Autophagy
Title: Podocytes maintain high basal levels of autophagy independent of mtor signaling.
Volume: 16
Issue: 11
Pages: 1932-1948
Publication
First Author: Lim J
Year: 2017
Journal: Sci Rep
Title: mTORC1 Signaling is a Critical Regulator of Postnatal Tendon Development.
Volume: 7
Issue: 1
Pages: 17175
Publication
First Author: Volovelsky O
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Hamartin regulates cessation of mouse nephrogenesis independently of Mtor.
Volume: 115
Issue: 23
Pages: 5998-6003
Publication
First Author: Castets P
Year: 2019
Journal: Nat Commun
Title: mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4.
Volume: 10
Issue: 1
Pages: 3187
Publication
First Author: Guridi M
Year: 2015
Journal: Sci Signal
Title: Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.
Volume: 8
Issue: 402
Pages: ra113
Publication
First Author: Liu Y
Year: 2020
Journal: Nat Commun
Title: The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Volume: 11
Issue: 1
Pages: 589
Publication
First Author: Dai Q
Year: 2017
Journal: Cell Death Differ
Title: mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression.
Volume: 24
Issue: 11
Pages: 1886-1899
Publication    
First Author: Covarrubias AJ
Year: 2016
Journal: Elife
Title: Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation.
Volume: 5
Publication    
First Author: Araujo A
Year: 2021
Journal: Elife
Title: IFN-γ mediates Paneth cell death via suppression of mTOR.
Volume: 10
Publication
First Author: Peterson TR
Year: 2011
Journal: Cell
Title: mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.
Volume: 146
Issue: 3
Pages: 408-20
Publication
First Author: Liu P
Year: 2017
Journal: Oncotarget
Title: Central role of mTORC1 downstream of YAP/TAZ in hepatoblastoma development.
Volume: 8
Issue: 43
Pages: 73433-73447
Publication
First Author: Xu XY
Year: 2009
Journal: Dev Dyn
Title: Characterization of p70 S6 kinase 1 in early development of mouse embryos.
Volume: 238
Issue: 12
Pages: 3025-34
Publication
First Author: Chakrabarti P
Year: 2010
Journal: Diabetes
Title: Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage.
Volume: 59
Issue: 4
Pages: 775-81
Publication
First Author: Kang YJ
Year: 2011
Journal: Cell Death Differ
Title: The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.
Volume: 18
Issue: 1
Pages: 133-44
Publication
First Author: Carter HN
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Contractile activity-induced mitochondrial biogenesis and mTORC1.
Volume: 303
Issue: 5
Pages: C540-7
Publication
First Author: Su KH
Year: 2016
Journal: Nat Cell Biol
Title: HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth.
Volume: 18
Issue: 5
Pages: 527-39
Publication
First Author: Dennis MD
Year: 2013
Journal: J Biol Chem
Title: Mechanistic target of rapamycin complex 1 (mTORC1)-mediated phosphorylation is governed by competition between substrates for interaction with raptor.
Volume: 288
Issue: 1
Pages: 10-9
Publication
First Author: Wolff NC
Year: 2011
Journal: Mol Cell Biol
Title: Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
Volume: 31
Issue: 9
Pages: 1870-84
Publication
First Author: Cunningham JT
Year: 2007
Journal: Nature
Title: mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
Volume: 450
Issue: 7170
Pages: 736-40
Publication
First Author: Feng D
Year: 2015
Journal: PLoS One
Title: mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC).
Volume: 10
Issue: 6
Pages: e0126240
Publication
First Author: Yi W
Year: 2017
Journal: Nat Commun
Title: The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity.
Volume: 8
Issue: 1
Pages: 254
Publication  
First Author: Huynh H
Year: 2018
Journal: Commun Biol
Title: mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1.
Volume: 1
Pages: 29
Publication
First Author: Imada S
Year: 2024
Journal: Nature
Title: Short-term post-fast refeeding enhances intestinal stemness via polyamines.
Volume: 633
Issue: 8031
Pages: 895-904
Publication
First Author: Ramírez JA
Year: 2019
Journal: J Immunol
Title: Folliculin Interacting Protein 1 Maintains Metabolic Homeostasis during B Cell Development by Modulating AMPK, mTORC1, and TFE3.
Volume: 203
Issue: 11
Pages: 2899-2908
Publication
First Author: Rodgers JT
Year: 2014
Journal: Nature
Title: mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).
Volume: 510
Issue: 7505
Pages: 393-6
Publication
First Author: Castro W
Year: 2018
Journal: Nat Immunol
Title: The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.
Volume: 19
Issue: 8
Pages: 809-820
Publication  
First Author: Huang WC
Year: 2016
Journal: Nat Commun
Title: Hyperconnectivity of prefrontal cortex to amygdala projections in a mouse model of macrocephaly/autism syndrome.
Volume: 7
Pages: 13421
Publication
First Author: Zhu X
Year: 2024
Journal: Nat Commun
Title: The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.
Volume: 15
Issue: 1
Pages: 10163
Publication
First Author: Hinden L
Year: 2022
Journal: Nat Commun
Title: Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function.
Volume: 13
Issue: 1
Pages: 1783
Publication
First Author: So L
Year: 2016
Journal: Sci Signal
Title: The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes.
Volume: 9
Issue: 430
Pages: ra57
Publication
First Author: Chen Y
Year: 2015
Journal: J Neurosci
Title: Pten Mutations Alter Brain Growth Trajectory and Allocation of Cell Types through Elevated β-Catenin Signaling.
Volume: 35
Issue: 28
Pages: 10252-67
Publication  
First Author: Lee PY
Year: 2017
Journal: Sci Immunol
Title: The metabolic regulator mTORC1 controls terminal myeloid differentiation.
Volume: 2
Issue: 11
Publication
First Author: Cho SH
Year: 2016
Journal: Nature
Title: Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.
Volume: 537
Issue: 7619
Pages: 234-238
Publication
First Author: Huang H
Year: 2019
Journal: Cell Death Dis
Title: AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration.
Volume: 10
Issue: 3
Pages: 203
Publication
First Author: Fu X
Year: 2018
Journal: J Clin Invest
Title: Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss.
Volume: 128
Issue: 11
Pages: 4938-4955