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Search results 1101 to 1153 out of 1153 for Ptf1a

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Type Details Score
HT Experiment
GSE55831 | Transcription Factor Network Specifying Inhibitory versus Excitatory Neurons in the Dorsal Spinal Cord [RNA-Seq]
Series Id: E-GEOD-55831
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1758520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7580782
Age: embryonic day 12.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2B'
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7580782
Age: embryonic day 10.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2A'
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7580782
Age: embryonic day 9.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2E
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7580782
Age: embryonic day 10.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2F
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:6695727
Age: embryonic day 9.5
Image: S3A/D Pdx-1
Note: Expression coincide with that of Ptf1a in vast majority of pancreatic epithelial cells from E9.5 to E10.5.
Specimen Label: S3A/D Pdx-1
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1715219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7580782
Age: embryonic day 11.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2G
Detected: true
Specimen Num: 18
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Publication
19067490 | -
First Author: Jiang Z
Year: 2008
Journal: PLoS Biol
Title: Exdpf is a key regulator of exocrine pancreas development controlled by retinoic acid and ptf1a in zebrafish.
Volume: 6
Issue: 11
Pages: e293
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GXD Expression
GXD Expression
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6695727
Age: embryonic day 10.5
Image: 5B Pdx-1
Note: Expression in pancreatic progenitor cells of dorsal pancreatic bud at E10.5 coinciding with Ptf1a and Ngn3 in scattered cells throughout pancreatic epithelium.
Specimen Label: 5B Pdx-1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6695359
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6695730
Age: embryonic day 10.5
Image: 5B Ngn3
Note: Expression in pancreatic progenitor cells of dorsal pancreatic bud at E10.5 coinciding with Ptf1a and Pdx1 in scattered cells throughout pancreatic epithelium.
Specimen Label: 5B Ngn3
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7520313
Age: embryonic day 12.5
Image: 3B/C
Note: Expression was predominantly localized in the ventricular zone. Overlapping Ptf1a and Olig2 expression in GABAergic precursors was observed in the intermediary region of the ventricular zone.
Specimen Label: 3B/C
Detected: true
Specimen Num: 1
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MP Term
MP:0021095 | abnormal dorsal interneuron 4 morphology
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Allele
Ptf1a<tm2Macd> | MGI:3771319
 
Name: pancreas specific transcription factor, 1a; targeted mutation 2, Raymond MacDonald
Allele Type: Targeted
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Allele
Ptf1a<tm3.1Mgn> | MGI:6470589
Name: pancreas specific transcription factor, 1a; targeted mutation 3.1, Mark A Magnuson
Allele Type: Targeted
Attribute String: Epitope tag, Reporter
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Allele
Ptf1a<tm3.1(rtTA)Mgn> | MGI:5467924
Name: pancreas specific transcription factor, 1a; targeted mutation 3.1, Mark A Magnuson
Allele Type: Targeted
Attribute String: RMCE-ready, Transactivator
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GXD Expression
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194375
Age: embryonic day 12.5
Image: 3A,G
Note: Triple labeling indicated that some Olig2-positive cells express Ptf1a (marker for GABAergic neuron progenitors) and other Olig2-positive cells express Lhx1 and Lhx5 (which mark postmitotic GABAergic neurons). The results indicate that Olig2 is expressed in both mitotic and postmitotic cells.
Specimen Label: 3A,G
Detected: true
Specimen Num: 2
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Publication
21844183 | -
First Author: Li Y
Year: 2011
Journal: Cancer Res
Title: Downregulation of RBMS3 is associated with poor prognosis in esophageal squamous cell carcinoma.
Volume: 71
Issue: 19
Pages: 6106-15
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Publication
23091072 | -
First Author: Jayasena CS
Year: 2012
Journal: J Cell Biol
Title: Rbms3 functions in craniofacial development by posttranscriptionally modulating TGF-β signaling.
Volume: 199
Issue: 3
Pages: 453-66
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Protein Domain
IPR034406 | RBMS3_RRM2
Type: Domain
Description: This entry represents the RNA recognition motif 2 (RRM2) of RBMS3 (RNA-binding motif, single-stranded-interacting protein 3). RBMS3 contains two RNA binding motifs and is closely related to the structure of the c-myc gene single-strand binding proteins (MSSPs). RBMS3 has been shown to exhibit tumour suppressor function via regulation of c-Myc and to bind/stabilize RNA in vitro []. It may posttranscriptionally regulate the transforming growth factor beta receptor pathway []. RBMS3 regulates the expression of Ptf1a (pancreas transcription factor 1 alpha subunit) [].
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Strain
MGI:6474321 | B6;129S6-Ptfl1a<tm3.1Mgn>/Vu
Attribute String: targeted mutation, mutant stock
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Strain
MGI:5312105 | B6.129S6(SJL)-Ptf1a<tm3.1(rtTA)Mgn>/Mmjax
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Ptf1a/Ptf1a
Background: involves: 129S6/SvEvTac
Zygosity: hm
Has Mutant Allele: true
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GXD Expression
GXD Expression
Probe: MGI:5560706
Assay Type: RNA in situ
Annotation Date: 2014-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5561118
Age: embryonic day 12.5
Image: 4B, A/B inlay, B/C inlay
Note: Expression was detected in ventricular layer. The signal overlaps with the caudal two thirds of Ptf1a (A/B inlay) and Mash1 (Ascl1 - B/C inlay). There was a gap in the expression domain (bracket) that is positive for Ptf1a and Mash1 (Ascl1).
Specimen Label: 4B, A/B inlay, B/C inlay
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5560706
Assay Type: RNA in situ
Annotation Date: 2014-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5561118
Age: embryonic day 12.5
Image: 4B', A'/B' inlay, B'/C' inlay
Note: Expression was detected in the ventricular layer. The signal overlaps with the caudal two thirds of Ptf1a (A/B inlay) and Mash1 (Ascl1 - B/C inlay). There was a gap in the expression domain (bracket) that is positive for Ptf1a and Mash1 (Ascl1).
Specimen Label: 4B', A'/B' inlay, B'/C' inlay
Detected: true
Specimen Num: 4
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HT Experiment
GSE108803 | Genome-wide chromatin accessibility and transcriptome profiling shows that minimal epigenome changes lead to coordinated transcriptional dysregulation of hedgehog signaling in Danforth's short tail mice (RNA-seq)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Cbll<Tg(Alb-KL)7-2Mhos> | MGI:3771564
Name: cerebelless; transgene insertion 7-2, Mikio Hoshino
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Null/knockout
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Allele
Ascl1<tm1(Neurog2)Fgu> | MGI:2388165
Name: achaete-scute family bHLH transcription factor 1; targeted mutation 1, Francois Guillemot
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
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Genotype
Genotype
Symbol: Ascl1/Ascl1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cbll/Cbll
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Allele
Lbx1<em1Mwil> | MGI:6864154
Name: ladybird homeobox 1; endonuclease-mediated mutation 1, Megan J Wilson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Tlx3<tm1Sjk> | MGI:2180105
Name: T cell leukemia, homeobox 3; targeted mutation 1, Stanley J Korsmeyer
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Tlx1/Tlx1 Tlx3/Tlx3
Background: involves: 129S2/SvPas * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ascl1/Ascl1 Neurog2/Neurog2
Background: involves: 129 * 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ptf1a/Ptf1a<+> Cbll/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ptf1a/Ptf1a
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tlx3/Tlx3
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax3/Pax3<+> Rbpj/Rbpj
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Publication
33786818 | J:308613
First Author: Schinzel F
Year: 2021
Journal: J Comp Neurol
Title: The Lbx1 lineage differentially contributes to inhibitory cell types of the dorsal cochlear nucleus, a cerebellum-like structure, and the cerebellum.
Volume: 529
Issue: 11
Pages: 3032-3045
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Publication
20807526 | J:165713
First Author: Pierreux CE
Year: 2010
Journal: Dev Biol
Title: Epithelial: Endothelial cross-talk regulates exocrine differentiation in developing pancreas.
Volume: 347
Issue: 1
Pages: 216-27
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Publication
29995913 | J:264433
First Author: Irhimeh MR
Year: 2018
Journal: PLoS One
Title: Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin-/VEGF-R2+ endothelial progenitor cells.
Volume: 13
Issue: 7
Pages: e0200194
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Publication
24370451 | J:206882
First Author: Hanotel J
Year: 2014
Journal: Dev Biol
Title: The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube.
Volume: 386
Issue: 2
Pages: 340-57
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Publication
19969077 | J:160281
First Author: Kobberup S
Year: 2010
Journal: Mech Dev
Title: Conditional control of the differentiation competence of pancreatic endocrine and ductal cells by Fgf10.
Volume: 127
Issue: 3-4
Pages: 220-34
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Protein Coding Gene
MGI:1351209 | Tlx3
Type: protein_coding_gene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Lbx1/Lbx1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Allele
Ascl1<tm1And> | MGI:1857470
Name: achaete-scute family bHLH transcription factor 1; targeted mutation 1, David J Anderson
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Ascl1/Ascl1
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
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Protein
Q8BWL5
Organism: Mus musculus/domesticus
Length: 431  
Fragment?: false
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Protein
Q8BKJ2
Organism: Mus musculus/domesticus
Length: 355  
Fragment?: false
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Protein
A0A6I8MX12
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
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Protein Coding Gene
MGI:96919 | Ascl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104867 | Lbx1
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Rbpj<tm1Hon> | MGI:3583755
Name: recombination signal binding protein for immunoglobulin kappa J region; targeted mutation 1, Tasuku Honjo
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Protein Coding Gene
MGI:96522 | Rbpj
Type: protein_coding_gene
Organism: mouse, laboratory
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