This entry represents the N-terminal domain of Utp10, which is a HEAT-repeat containing protein involved in nucleolar processing of pre-18S ribosomal RNA []. Utp10 is also involved in 40S ribosome maturation []. Proteins containing this domain also include HEATR1 from humans. HEATR1 is required for optimal pre-ribosomal RNA transcription by RNA polymerase I [].
Proteins in this entry contain an armadillo-type fold, and a BP28, C-terminal domain. This entry includes U3 small nucleolar RNA-associated protein 10 (Utp10), which is a HEAT-repeat containing protein involved in nucleolar processing of pre-18S ribosomal RNA []. Utp10 is also involved in 40S ribosome maturation []. This entry also includes HEAT repeat-containing protein 1 (HEATR1) from humans. HEATR1 is required for optimal pre-ribosomal RNA transcription by RNA polymerase I [].
