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Search results 1 to 100 out of 216 for Prkci

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Category: Publication
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Type Details Score
Publication
28698296 | J:243895
First Author: Sarkar S
Year: 2017
Journal: Genes Dev
Title: PRKCI promotes immune suppression in ovarian cancer.
Volume: 31
Issue: 11
Pages: 1109-1121
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Publication
35675330 | J:326080
First Author: Weatherly SM
Year: 2022
Journal: PLoS Genet
Title: Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1rd8 mouse model.
Volume: 18
Issue: 6
Pages: e1009798
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Publication
27653691 | J:239118
First Author: Nakanishi Y
Year: 2016
Journal: Cell Rep
Title: Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι.
Volume: 16
Issue: 12
Pages: 3297-3310
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Publication
31378680 | J:278962
First Author: Yin N
Year: 2019
Journal: Cancer Cell
Title: Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma.
Volume: 36
Issue: 2
Pages: 156-167.e7
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Publication
19738040 | J:153508
First Author: Regala RP
Year: 2009
Journal: Cancer Res
Title: Atypical protein kinase C{iota} is required for bronchioalveolar stem cell expansion and lung tumorigenesis.
Volume: 69
Issue: 19
Pages: 7603-11
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Publication
26876178 | J:315122
First Author: Passer D
Year: 2016
Journal: Cell Rep
Title: Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation.
Volume: 14
Issue: 7
Pages: 1662-1672
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Publication
22349825 | J:244534
First Author: Kikuchi K
Year: 2013
Journal: Oncogene
Title: Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma.
Volume: 32
Issue: 3
Pages: 286-95
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Publication
23446420 | J:194840
First Author: Atwood SX
Year: 2013
Journal: Nature
Title: GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.
Volume: 494
Issue: 7438
Pages: 484-8
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Publication
15322187 | J:92719
First Author: Soloff RS
Year: 2004
Journal: J Immunol
Title: Targeted deletion of protein kinase C lambda reveals a distribution of functions between the two atypical protein kinase C isoforms.
Volume: 173
Issue: 5
Pages: 3250-60
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Publication
22579248 | J:247393
First Author: Wang C
Year: 2012
Journal: Structure
Title: Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKCι in complex with a substrate peptide from Par-3.
Volume: 20
Issue: 5
Pages: 791-801
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Publication
27226486 | J:278595
First Author: Forteza R
Year: 2016
Journal: Mol Biol Cell
Title: Conditional knockout of polarity complex (atypical) PKCι reveals an anti-inflammatory function mediated by NF-κB.
Volume: 27
Issue: 14
Pages: 2186-97
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Publication
33596087 | J:308617
First Author: Mashukova A
Year: 2021
Journal: Mol Biol Cell
Title: The cell polarity kinase Par1b/MARK2 activation selects specific NF-kB transcripts via phosphorylation of core mediator Med17/TRAP80.
Volume: 32
Issue: 8
Pages: 690-702
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Publication
22225955 | J:218585
First Author: Sajan MP
Year: 2012
Journal: Metabolism
Title: Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-ι.
Volume: 61
Issue: 4
Pages: 459-69
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Publication
19279126 | J:164628
First Author: Huber TB
Year: 2009
Journal: J Am Soc Nephrol
Title: Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome.
Volume: 20
Issue: 4
Pages: 798-806
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Publication
17641777 | J:123964
First Author: Farese RV
Year: 2007
Journal: J Clin Invest
Title: Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes.
Volume: 117
Issue: 8
Pages: 2289-301
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Publication
19887597 | J:169947
First Author: Sajan MP
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.
Volume: 298
Issue: 2
Pages: E179-92
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Publication
28073831 | J:246158
First Author: Dorfman MD
Year: 2017
Journal: Diabetes
Title: Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity.
Volume: 66
Issue: 4
Pages: 920-934
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Publication
19202134 | J:149920
First Author: Sajan MP
Year: 2009
Journal: J Lipid Res
Title: The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesity.
Volume: 50
Issue: 6
Pages: 1133-45
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Publication
34560002 | J:315700
First Author: Linares JF
Year: 2021
Journal: Mol Cell
Title: PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis.
Volume: 81
Issue: 21
Pages: 4509-4526.e10
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Publication
15630453 | J:95378
First Author: Hashimoto N
Year: 2005
Journal: J Clin Invest
Title: PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells.
Volume: 115
Issue: 1
Pages: 138-45
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Publication
28383692 | J:262316
First Author: Sheng T
Year: 2017
Journal: Cereb Cortex
Title: Learning-Induced Suboptimal Compensation for PKCι/λ Function in Mutant Mice.
Volume: 27
Issue: 6
Pages: 3284-3293
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Publication
24877563 | J:216249
First Author: Sajan MP
Year: 2014
Journal: Mol Endocrinol
Title: PKCλ haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.
Volume: 28
Issue: 7
Pages: 1097-107
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Publication
16136042 | J:101716
First Author: Burguière E
Year: 2005
Journal: Nat Neurosci
Title: Spatial navigation impairment in mice lacking cerebellar LTD: a motor adaptation deficit?
Volume: 8
Issue: 10
Pages: 1292-4
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Publication
9819385 | J:148082
First Author: Kotani K
Year: 1998
Journal: Mol Cell Biol
Title: Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes.
Volume: 18
Issue: 12
Pages: 6971-82
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8575788 | J:29381
First Author: Quaderi NA
Year: 1995
Journal: Genomics
Title: Genetic mapping of a gene encoding an atypical protein kinase C, protein kinase C lambda, to the proximal region of mouse chromosome 3.
Volume: 29
Issue: 3
Pages: 815-6
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Publication
18628308 | J:139809
First Author: Kishikawa M
Year: 2008
Journal: J Cell Sci
Title: aPKC enables development of zonula adherens by antagonizing centripetal contraction of the circumferential actomyosin cables.
Volume: 121
Issue: Pt 15
Pages: 2481-92
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Publication
19768116 | J:153614
First Author: Dard N
Year: 2009
Journal: PLoS One
Title: Inactivation of aPKClambda reveals a context dependent allocation of cell lineages in preimplantation mouse embryos.
Volume: 4
Issue: 9
Pages: e7117
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Publication
29305916 | J:262164
First Author: Yang Y
Year: 2018
Journal: Biochim Biophys Acta
Title: PKCλ/ι regulates Th17 differentiation and house dust mite-induced allergic airway inflammation.
Volume: 1864
Issue: 3
Pages: 934-941
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Publication
24096077 | J:202823
First Author: Worthmann K
Year: 2013
Journal: Am J Pathol
Title: Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) λ/ι.
Volume: 183
Issue: 6
Pages: 1945-59
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Publication
24092753 | J:204985
First Author: Xing B
Year: 2013
Journal: J Biol Chem
Title: Atypical protein kinase Cλ is critical for growth factor receptor-induced dorsal ruffle turnover and cell migration.
Volume: 288
Issue: 46
Pages: 32827-36
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Publication
14615604 | J:87746
First Author: Bandyopadhyay G
Year: 2004
Journal: Mol Endocrinol
Title: Protein kinase C-lambda knockout in embryonic stem cells and adipocytes impairs insulin-stimulated glucose transport.
Volume: 18
Issue: 2
Pages: 373-83
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Publication
24019538 | J:201737
First Author: Niessen MT
Year: 2013
Journal: J Cell Biol
Title: aPKCλ controls epidermal homeostasis and stem cell fate through regulation of division orientation.
Volume: 202
Issue: 6
Pages: 887-900
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Publication
23334392 | J:311485
First Author: Hartleben B
Year: 2013
Journal: J Am Soc Nephrol
Title: aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation.
Volume: 24
Issue: 2
Pages: 253-67
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Publication
29032894 | J:258056
 
First Author: Sajan MP
Year: 2018
Journal: Neurobiol Aging
Title: Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's disease.
Volume: 61
Pages: 225-237
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32589943 | J:296308
First Author: Kudo Y
Year: 2020
Journal: Cancer Cell
Title: PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression.
Volume: 38
Issue: 2
Pages: 247-262.e11
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Publication
30610188 | J:270586
First Author: Nayak RC
Year: 2019
Journal: Nat Commun
Title: The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors.
Volume: 10
Issue: 1
Pages: 46
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33207226 | J:300513
First Author: Kasashima H
Year: 2021
Journal: Dev Cell
Title: Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population.
Volume: 56
Issue: 1
Pages: 95-110.e10
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21653884 | J:173454
First Author: Sengupta A
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity and blood formation.
Volume: 108
Issue: 24
Pages: 9957-62
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Publication
12975478 | J:118462
First Author: Matsumoto M
Year: 2003
Journal: J Clin Invest
Title: PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity.
Volume: 112
Issue: 6
Pages: 935-44
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Publication
25617472 | J:232677
First Author: Metz PJ
Year: 2015
Journal: J Immunol
Title: Regulation of asymmetric division and CD8+ T lymphocyte fate specification by protein kinase Cζ and protein kinase Cλ/ι.
Volume: 194
Issue: 5
Pages: 2249-59
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Publication
26076315 | J:226198
First Author: Osada SI
Year: 2015
Journal: J Invest Dermatol
Title: Atypical Protein Kinase C Isoform, aPKCλ, Is Essential for Maintaining Hair Follicle Stem Cell Quiescence.
Volume: 135
Issue: 11
Pages: 2584-2592
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30660448 | J:295068
First Author: Noguchi N
Year: 2019
Journal: J Dermatol Sci
Title: Atypical protein kinase C isoforms differentially regulate directional keratinocyte migration during wound healing.
Volume: 93
Issue: 2
Pages: 101-108
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Publication
16931174 | J:115984
First Author: Kovac J
Year: 2007
Journal: Gene Expr Patterns
Title: Expression of the atypical protein kinase C (aPKC) isoforms iota/lambda and zeta during mouse embryogenesis.
Volume: 7
Issue: 1-2
Pages: 187-96
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Publication
15024028 | J:89285
First Author: Murray NR
Year: 2004
Journal: J Cell Biol
Title: Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
Volume: 164
Issue: 6
Pages: 797-802
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27760826 | J:308383
First Author: Xiong X
Year: 2016
Journal: J Biol Chem
Title: Pleckstrin Homology (PH) Domain Leucine-rich Repeat Protein Phosphatase Controls Cell Polarity by Negatively Regulating the Activity of Atypical Protein Kinase C.
Volume: 291
Issue: 48
Pages: 25167-25178
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8797824 | J:35282
First Author: Díaz-Meco MT
Year: 1996
Journal: Cell
Title: The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C.
Volume: 86
Issue: 5
Pages: 777-86
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15657073 | J:95628
First Author: Plusa B
Year: 2005
Journal: J Cell Sci
Title: Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo.
Volume: 118
Issue: Pt 3
Pages: 505-15
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Publication
21659643 | J:191854
First Author: Qi Y
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Cdc42 controls vascular network assembly through protein kinase Cι during embryonic vasculogenesis.
Volume: 31
Issue: 8
Pages: 1861-70
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23213435 | J:184584
First Author: Seidl S
Year: 2012
Journal: Biol Open
Title: Functional comparison of protein domains within aPKCs involved in nucleocytoplasmic shuttling.
Volume: 1
Issue: 5
Pages: 436-45
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38092754 | J:343423
First Author: Muta Y
Year: 2023
Journal: Nat Commun
Title: Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis.
Volume: 14
Issue: 1
Pages: 8075
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22359542 | J:185224
First Author: Scotti ML
Year: 2012
Journal: PLoS One
Title: Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia.
Volume: 7
Issue: 2
Pages: e30509
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29789715 | J:274161
First Author: Vorhagen S
Year: 2018
Journal: Oncogene
Title: Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis.
Volume: 37
Issue: 37
Pages: 5136-5146
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30827887 | J:273246
First Author: Reina-Campos M
Year: 2019
Journal: Cancer Cell
Title: Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer.
Volume: 35
Issue: 3
Pages: 385-400.e9
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23791731 | J:199829
First Author: Hirate Y
Year: 2013
Journal: Curr Biol
Title: Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos.
Volume: 23
Issue: 13
Pages: 1181-94
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19528321 | J:149986
First Author: McCaffrey LM
Year: 2009
Journal: Genes Dev
Title: The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis.
Volume: 23
Issue: 12
Pages: 1450-60
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19549684 | J:153162
First Author: Mashukova A
Year: 2009
Journal: J Cell Sci
Title: Rescue of atypical protein kinase C in epithelia by the cytoskeleton and Hsp70 family chaperones.
Volume: 122
Issue: Pt 14
Pages: 2491-503
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17313651 | J:225407
First Author: Fritzius T
Year: 2007
Journal: FEBS J
Title: WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta.
Volume: 274
Issue: 6
Pages: 1552-66
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27487217 | J:269076
First Author: Maître JL
Year: 2016
Journal: Nature
Title: Asymmetric division of contractile domains couples cell positioning and fate specification.
Volume: 536
Issue: 7616
Pages: 344-348
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19147581 | J:143707
First Author: Murray NR
Year: 2009
Journal: Cancer Res
Title: Protein kinase C betaII and PKCiota/lambda: collaborating partners in colon cancer promotion and progression.
Volume: 69
Issue: 2
Pages: 656-62
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30552022 | J:305332
First Author: Nakanishi Y
Year: 2018
Journal: Immunity
Title: Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance.
Volume: 49
Issue: 6
Pages: 1132-1147.e7
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34818553 | J:332501
First Author: Kenchappa RS
Year: 2021
Journal: Cell Rep
Title: Protein kinase C(ι) and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities.
Volume: 37
Issue: 8
Pages: 110054
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19142224 | J:144995
First Author: Hirose T
Year: 2009
Journal: PLoS One
Title: An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.
Volume: 4
Issue: 1
Pages: e4194
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24391875 | J:211115
First Author: Yamanaka T
Year: 2013
Journal: PLoS One
Title: Loss of aPKCλ in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains.
Volume: 8
Issue: 12
Pages: e84036
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15766745 | J:98298
First Author: Michaut MA
Year: 2005
Journal: Dev Biol
Title: Phosphorylated MARCKS: a novel centrosome component that also defines a peripheral subdomain of the cortical actin cap in mouse eggs.
Volume: 280
Issue: 1
Pages: 26-37
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18032449 | J:130194
First Author: Costa MR
Year: 2008
Journal: Development
Title: Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex.
Volume: 135
Issue: 1
Pages: 11-22
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33547760 | J:304327
First Author: Chen Z
Year: 2021
Journal: Genesis
Title: Atypical protein kinase C is essential for embryonic vascular development in mice.
Volume: 59
Issue: 3
Pages: e23412
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16792529 | J:225409
First Author: Fritzius T
Year: 2006
Journal: Biochem J
Title: A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda.
Volume: 399
Issue: 1
Pages: 9-20
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10934474 | J:69174
First Author: Joberty G
Year: 2000
Journal: Nat Cell Biol
Title: The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.
Volume: 2
Issue: 8
Pages: 531-9
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10934475 | J:63704
First Author: Lin D
Year: 2000
Journal: Nat Cell Biol
Title: A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity.
Volume: 2
Issue: 8
Pages: 540-7
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19668197 | J:158132
First Author: Mori D
Year: 2009
Journal: Nat Cell Biol
Title: An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics.
Volume: 11
Issue: 9
Pages: 1057-68
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7513693 | J:17835
First Author: Akimoto K
Year: 1994
Journal: J Biol Chem
Title: A new member of the third class in the protein kinase C family, PKC lambda, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells.
Volume: 269
Issue: 17
Pages: 12677-83
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12832475 | J:84324
First Author: Imamura T
Year: 2003
Journal: Mol Cell Biol
Title: Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin.
Volume: 23
Issue: 14
Pages: 4892-900
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28643773 | J:250568
 
First Author: Dütting S
Year: 2017
Journal: Nat Commun
Title: A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis.
Volume: 8
Pages: 15838
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23354168 | J:195218
First Author: Nakayama M
Year: 2013
Journal: Nat Cell Biol
Title: Spatial regulation of VEGF receptor endocytosis in angiogenesis.
Volume: 15
Issue: 3
Pages: 249-60
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33129760 | J:300338
First Author: De La Cena KOC
Year: 2021
Journal: Am J Pathol
Title: Transmembrane and Immunoglobulin Domain Containing 1, a Putative Tumor Suppressor, Induces G2/M Cell Cycle Checkpoint Arrest in Colon Cancer Cells.
Volume: 191
Issue: 1
Pages: 157-167
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14983036 | J:88645
First Author: Gharavi AG
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Mapping a locus for susceptibility to HIV-1-associated nephropathy to mouse chromosome 3.
Volume: 101
Issue: 8
Pages: 2488-93
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30157434 | J:271615
First Author: Haag N
Year: 2018
Journal: Cell Rep
Title: The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea.
Volume: 24
Issue: 9
Pages: 2418-2431.e6
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20152182 | J:157918
First Author: Wang J
Year: 2010
Journal: Dev Cell
Title: CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain.
Volume: 18
Issue: 1
Pages: 114-25
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30126902 | J:270954
 
First Author: Bankaitis ED
Year: 2018
Journal: Development
Title: ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche.
Volume: 145
Issue: 18
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14685273 | J:87877
First Author: Parkinson SJ
Year: 2004
Journal: EMBO J
Title: Identification of PKCzetaII: an endogenous inhibitor of cell polarity.
Volume: 23
Issue: 1
Pages: 77-88
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15581362 | J:94676
First Author: Miura A
Year: 2004
Journal: Biochemistry
Title: Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes.
Volume: 43
Issue: 49
Pages: 15503-9
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18466329 | J:139368
First Author: Wang G
Year: 2008
Journal: J Neurochem
Title: Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain development.
Volume: 106
Issue: 2
Pages: 718-33
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Publication
26944093 | J:231671
First Author: Xu B
Year: 2016
Journal: Dev Biol
Title: Protein tyrosine kinase 7 is essential for tubular morphogenesis of the Wolffian duct.
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