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Search results 1 to 100 out of 109 for Pkhd1

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Category: Publication
Type Details Score
Publication
First Author: Zhang MZ
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells.
Volume: 101
Issue: 8
Pages: 2311-6
Publication
First Author: Williams SS
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Tissue-specific regulation of the mouse Pkhd1 (ARPKD) gene promoter.
Volume: 307
Issue: 3
Pages: F356-68
Publication
First Author: Bakeberg JL
Year: 2011
Journal: J Am Soc Nephrol
Title: Epitope-tagged Pkhd1 tracks the processing, secretion, and localization of fibrocystin.
Volume: 22
Issue: 12
Pages: 2266-77
Publication
First Author: Yang C
Year: 2023
Journal: J Mol Med (Berl)
Title: Pkhd1(cyli/cyli) mice have altered renal Pkhd1 mRNA processing and hormonally sensitive liver disease.
Volume: 101
Issue: 9
Pages: 1141-1151
Publication
First Author: Menezes LF
Year: 2004
Journal: Kidney Int
Title: Polyductin, the PKHD1 gene product, comprises isoforms expressed in plasma membrane, primary cilium, and cytoplasm.
Volume: 66
Issue: 4
Pages: 1345-55
Publication
First Author: Mai W
Year: 2005
Journal: Mol Biol Cell
Title: Inhibition of Pkhd1 impairs tubulomorphogenesis of cultured IMCD cells.
Volume: 16
Issue: 9
Pages: 4398-409
Publication
First Author: Hu B
Year: 2011
Journal: Exp Cell Res
Title: Cystogenesis in ARPKD results from increased apoptosis in collecting duct epithelial cells of Pkhd1 mutant kidneys.
Volume: 317
Issue: 2
Pages: 173-87
Publication
First Author: Hiesberger T
Year: 2004
Journal: J Clin Invest
Title: Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice.
Volume: 113
Issue: 6
Pages: 814-25
Publication
First Author: Hiesberger T
Year: 2005
Journal: J Biol Chem
Title: Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis.
Volume: 280
Issue: 11
Pages: 10578-86
Publication
First Author: Richards T
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling.
Volume: 1865
Issue: 2
Pages: 378-390
Publication
First Author: Ward CJ
Year: 2002
Journal: Nat Genet
Title: The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein.
Volume: 30
Issue: 3
Pages: 259-69
Publication
First Author: Zhang J
Year: 2010
Journal: Hum Mol Genet
Title: Polycystic kidney disease protein fibrocystin localizes to the mitotic spindle and regulates spindle bipolarity.
Volume: 19
Issue: 17
Pages: 3306-19
Publication
First Author: Patel V
Year: 2011
Journal: J Am Soc Nephrol
Title: Tagged fibrocystin sheds its secrets.
Volume: 22
Issue: 12
Pages: 2148-50
Publication
First Author: Huang W
Year: 2018
Journal: J Immunol
Title: A Novel Pkhd1 Mutation Interacts with the Nonobese Diabetic Genetic Background To Cause Autoimmune Cholangitis.
Volume: 200
Issue: 1
Pages: 147-162
Publication
First Author: Nishio S
Year: 2010
Journal: J Am Soc Nephrol
Title: Loss of oriented cell division does not initiate cyst formation.
Volume: 21
Issue: 2
Pages: 295-302
Publication
First Author: Kaimori JY
Year: 2007
Journal: Hum Mol Genet
Title: Polyductin undergoes notch-like processing and regulated release from primary cilia.
Volume: 16
Issue: 8
Pages: 942-56
Publication
First Author: Gallagher AR
Year: 2008
Journal: Am J Pathol
Title: Biliary and pancreatic dysgenesis in mice harboring a mutation in Pkhd1.
Volume: 172
Issue: 2
Pages: 417-29
Publication
First Author: Williams SS
Year: 2008
Journal: Pediatr Nephrol
Title: Kidney cysts, pancreatic cysts, and biliary disease in a mouse model of autosomal recessive polycystic kidney disease.
Volume: 23
Issue: 5
Pages: 733-41
Publication
First Author: Xiong H
Year: 2002
Journal: Genomics
Title: A novel gene encoding a TIG multiple domain protein is a positional candidate for autosomal recessive polycystic kidney disease.
Volume: 80
Issue: 1
Pages: 96-104
Publication
First Author: Nagasawa Y
Year: 2002
Journal: J Am Soc Nephrol
Title: Identification and characterization of Pkhd1, the mouse orthologue of the human ARPKD gene.
Volume: 13
Issue: 9
Pages: 2246-58
Publication
First Author: Moser M
Year: 2005
Journal: Hepatology
Title: A mouse model for cystic biliary dysgenesis in autosomal recessive polycystic kidney disease (ARPKD).
Volume: 41
Issue: 5
Pages: 1113-21
Publication
First Author: Shan D
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Heterozygous Pkhd1C642* mice develop cystic liver disease and proximal tubule ectasia that mimics radiographic signs of medullary sponge kidney.
Volume: 316
Issue: 3
Pages: F463-F472
Publication
First Author: Wang S
Year: 2007
Journal: Mol Cell Biol
Title: Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.
Volume: 27
Issue: 8
Pages: 3241-52
Publication
First Author: Kim I
Year: 2008
Journal: J Am Soc Nephrol
Title: Fibrocystin/polyductin modulates renal tubular formation by regulating polycystin-2 expression and function.
Volume: 19
Issue: 3
Pages: 455-68
Publication
First Author: Fabris L
Year: 2022
Journal: FASEB J
Title: Dysregulation of the Scribble/YAP/β-catenin axis sustains the fibroinflammatory response in a PKHD1-/- mouse model of congenital hepatic fibrosis.
Volume: 36
Issue: 6
Pages: e22364
Publication
First Author: Zhang YJ
Year: 2023
Journal: FASEB J
Title: Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells: A mechanistic connection between the kidney defects in cpk mice and human ARPKD.
Volume: 37
Issue: 7
Pages: e23008
Publication
First Author: Boddu R
Year: 2014
Journal: J Mol Med (Berl)
Title: Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.
Volume: 92
Issue: 10
Pages: 1045-56
Publication
First Author: Garcia-Gonzalez MA
Year: 2007
Journal: Hum Mol Genet
Title: Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.
Volume: 16
Issue: 16
Pages: 1940-50
Publication
First Author: Patel V
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: miR-17~92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease.
Volume: 110
Issue: 26
Pages: 10765-70
Publication
First Author: Hossain Z
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.
Volume: 104
Issue: 5
Pages: 1631-6
Publication
First Author: Fedeles SV
Year: 2011
Journal: Nat Genet
Title: A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation.
Volume: 43
Issue: 7
Pages: 639-47
Publication
First Author: Hiesberger T
Year: 2006
Journal: J Biol Chem
Title: Proteolytic cleavage and nuclear translocation of fibrocystin is regulated by intracellular Ca2+ and activation of protein kinase C.
Volume: 281
Issue: 45
Pages: 34357-64
Publication
First Author: Woollard JR
Year: 2007
Journal: Kidney Int
Title: A mouse model of autosomal recessive polycystic kidney disease with biliary duct and proximal tubule dilatation.
Volume: 72
Issue: 3
Pages: 328-36
Publication
First Author: Nagano J
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling.
Volume: 338
Issue: 2
Pages: 880-9
Publication
First Author: Masyuk TV
Year: 2012
Journal: Gastroenterology
Title: Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease.
Volume: 142
Issue: 3
Pages: 622-633.e4
Publication
First Author: Kim I
Year: 2008
Journal: J Biol Chem
Title: Polycystin-2 expression is regulated by a PC2-binding domain in the intracellular portion of fibrocystin.
Volume: 283
Issue: 46
Pages: 31559-66
Publication
First Author: Masyuk AI
Year: 2010
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia.
Volume: 299
Issue: 4
Pages: G990-9
Publication
First Author: Outeda P
Year: 2017
Journal: Kidney Int
Title: A novel model of autosomal recessive polycystic kidney questions the role of the fibrocystin C-terminus in disease mechanism.
Volume: 92
Issue: 5
Pages: 1130-1144
Publication
First Author: Hu Q
Year: 2010
Journal: Science
Title: A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution.
Volume: 329
Issue: 5990
Pages: 436-9
Publication
First Author: Masyuk TV
Year: 2014
Journal: Am J Pathol
Title: Centrosomal abnormalities characterize human and rodent cystic cholangiocytes and are associated with Cdc25A overexpression.
Volume: 184
Issue: 1
Pages: 110-21
Publication
First Author: Walker RV
Year: 2023
Journal: Nat Commun
Title: Fibrocystin/Polyductin releases a C-terminal fragment that translocates into mitochondria and suppresses cystogenesis.
Volume: 14
Issue: 1
Pages: 6513
Publication
First Author: Follit JA
Year: 2014
Journal: PLoS Genet
Title: Arf4 is required for Mammalian development but dispensable for ciliary assembly.
Volume: 10
Issue: 2
Pages: e1004170
Publication
First Author: Lian P
Year: 2014
Journal: PLoS One
Title: Loss of polycystin-1 inhibits Bicc1 expression during mouse development.
Volume: 9
Issue: 3
Pages: e88816
Publication
First Author: Tran U
Year: 2010
Journal: Development
Title: The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity.
Volume: 137
Issue: 7
Pages: 1107-16
Publication  
First Author: Yue H
Year: 2021
Journal: Front Neurol
Title: Down-Regulation of Inpp5e Associated With Abnormal Ciliogenesis During Embryonic Neurodevelopment Under Inositol Deficiency.
Volume: 12
Pages: 579998
Publication
First Author: Makita R
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.
Volume: 294
Issue: 3
Pages: F542-53
Publication
First Author: Pierreux CE
Year: 2006
Journal: Gastroenterology
Title: The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.
Volume: 130
Issue: 2
Pages: 532-41
Publication
First Author: Rasouly HM
Year: 2016
Journal: Kidney Int
Title: Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.
Volume: 90
Issue: 6
Pages: 1262-1273
Publication
First Author: Badgandi HB
Year: 2017
Journal: J Cell Biol
Title: Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.
Volume: 216
Issue: 3
Pages: 743-760
Publication
First Author: Higashiyama H
Year: 2017
Journal: Development
Title: Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia.
Volume: 144
Issue: 10
Pages: 1906-1917
Publication
First Author: Desgrange A
Year: 2017
Journal: Development
Title: HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis.
Volume: 144
Issue: 24
Pages: 4704-4719
Publication
First Author: De Vas MG
Year: 2015
Journal: Development
Title: Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors.
Volume: 142
Issue: 5
Pages: 871-82
Publication  
First Author: Niborski LL
Year: 2021
Journal: Dis Model Mech
Title: Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.
Volume: 14
Issue: 5
Publication      
First Author: The Mammalian Genetics Unit at Harwell
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK
Publication
First Author: Yates LL
Year: 2010
Journal: Hum Mol Genet
Title: The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
Volume: 19
Issue: 23
Pages: 4663-76
Publication      
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
Publication
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication  
First Author: Kuo IY
Year: 2019
Journal: Sci Signal
Title: Polycystin 2 regulates mitochondrial Ca2+ signaling, bioenergetics, and dynamics through mitofusin 2.
Volume: 12
Issue: 580
Publication
First Author: He QY
Year: 2006
Journal: Bioinformatics
Title: G8: a novel domain associated with polycystic kidney disease and non-syndromic hearing loss.
Volume: 22
Issue: 18
Pages: 2189-91
Publication
First Author: Raman A
Year: 2017
Journal: J Am Soc Nephrol
Title: Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease.
Volume: 28
Issue: 9
Pages: 2708-2719
Publication
First Author: Wang Q
Year: 2018
Journal: Kidney Int
Title: Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease.
Volume: 93
Issue: 2
Pages: 403-415
Publication
First Author: Cao Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models.
Volume: 106
Issue: 51
Pages: 21819-24
Publication
First Author: Trott JF
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis.
Volume: 315
Issue: 6
Pages: F1855-F1868
Publication  
First Author: Grosch M
Year: 2021
Journal: J Cell Sci
Title: A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
Volume: 134
Issue: 16
Publication
First Author: Zhou X
Year: 2015
Journal: Hum Mol Genet
Title: Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
Volume: 24
Issue: 14
Pages: 3982-93
Publication
First Author: Aboudehen K
Year: 2017
Journal: J Am Soc Nephrol
Title: Hepatocyte Nuclear Factor-1β Regulates Urinary Concentration and Response to Hypertonicity.
Volume: 28
Issue: 10
Pages: 2887-2900
Publication
First Author: Ye H
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: The regulatory 1α subunit of protein kinase A modulates renal cystogenesis.
Volume: 313
Issue: 3
Pages: F677-F686
Publication
First Author: Aboudehen K
Year: 2018
Journal: J Biol Chem
Title: Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling.
Volume: 293
Issue: 24
Pages: 9388-9398
Publication
First Author: Besse W
Year: 2017
Journal: J Clin Invest
Title: Isolated polycystic liver disease genes define effectors of polycystin-1 function.
Volume: 127
Issue: 5
Pages: 1772-1785
Publication
First Author: Hogan MC
Year: 2003
Journal: Hum Mol Genet
Title: PKHDL1, a homolog of the autosomal recessive polycystic kidney disease gene, encodes a receptor with inducible T lymphocyte expression.
Volume: 12
Issue: 6
Pages: 685-98
Publication
First Author: Gresh L
Year: 2004
Journal: EMBO J
Title: A transcriptional network in polycystic kidney disease.
Volume: 23
Issue: 7
Pages: 1657-68
Publication
First Author: Belyea BC
Year: 2023
Journal: Clin Sci (Lond)
Title: Overexpression of notch signaling in renin cells leads to a polycystic kidney phenotype.
Volume: 137
Issue: 1
Pages: 35-45
Publication
First Author: Ferrè S
Year: 2019
Journal: Kidney Int
Title: Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation.
Volume: 96
Issue: 6
Pages: 1359-1373
Publication
First Author: Flowers EM
Year: 2018
Journal: Nat Commun
Title: Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.
Volume: 9
Issue: 1
Pages: 814
Publication  
First Author: Lakhia R
Year: 2020
Journal: JCI Insight
Title: Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression.
Volume: 5
Issue: 7
Publication      
First Author: Ishikawa Y
Year: 2019
Journal: J Am Soc Nephrol
Title: Spliced XBP1 Rescues Renal Interstitial Inflammation Due to Loss of Sec63 in Collecting Ducts.
Publication
First Author: Chen L
Year: 2015
Journal: J Clin Invest
Title: Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease.
Volume: 125
Issue: 6
Pages: 2399-412
Publication
First Author: Cai Y
Year: 2014
Journal: J Clin Invest
Title: Altered trafficking and stability of polycystins underlie polycystic kidney disease.
Volume: 124
Issue: 12
Pages: 5129-44