Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6251497 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:6251523 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
FcgR1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6251497 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6251524 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
FcgR1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6251497 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684626 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6251525 |
Age: |
embryonic day 19.5 |
|
|
Specimen Label: |
FcgR1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamaji K |
Year: |
2005 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Evidence for Cd101 but not Fcgr1 as candidate for type 1 diabetes locus, Idd10. |
Volume: |
331 |
Issue: |
2 |
Pages: |
536-42 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
330
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Prins JB |
Year: |
1993 |
Journal: |
Science |
Title: |
Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice. |
Volume: |
260 |
Issue: |
5108 |
Pages: |
695-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bersellini Farinotti A |
Year: |
2019 |
Journal: |
J Exp Med |
Title: |
Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons. |
Volume: |
216 |
Issue: |
8 |
Pages: |
1904-1924 |
|
•
•
•
•
•
|
Publication |
First Author: |
Podolin PL |
Year: |
1997 |
Journal: |
J Immunol |
Title: |
Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1. |
Volume: |
159 |
Issue: |
4 |
Pages: |
1835-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gavin AL |
Year: |
2000 |
Journal: |
Immunogenetics |
Title: |
Mouse FcgammaRI: identification and functional characterization of five new alleles. |
Volume: |
51 |
Issue: |
3 |
Pages: |
206-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2019 |
Journal: |
J Clin Invest |
Title: |
Neuronal FcγRI mediates acute and chronic joint pain. |
Volume: |
129 |
Issue: |
9 |
Pages: |
3754-3769 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ikegami H |
Year: |
2003 |
Journal: |
Ann N Y Acad Sci |
Title: |
Congenic mapping and candidate sequencing of susceptibility genes for Type 1 diabetes in the NOD mouse. |
Volume: |
1005 |
|
Pages: |
196-204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scott CL |
Year: |
2018 |
Journal: |
Immunity |
Title: |
The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages. |
Volume: |
49 |
Issue: |
2 |
Pages: |
312-325.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kotov DI |
Year: |
2023 |
Journal: |
Cell |
Title: |
Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis. |
Volume: |
186 |
Issue: |
25 |
Pages: |
5536-5553.e22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van Hove H |
Year: |
2019 |
Journal: |
Nat Neurosci |
Title: |
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1021-1035 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2023 |
Journal: |
Nature |
Title: |
Reprogramming tumour-associated macrophages to outcompete cancer cells. |
Volume: |
619 |
Issue: |
7970 |
Pages: |
616-623 |
|
•
•
•
•
•
|
Allele |
Name: |
deletion, Chr 3, Synbal 1 |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
No functional change |
|
•
•
•
•
•
|
Publication |
First Author: |
Mutant Mouse Regional Resource Centers |
Year: |
2004 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Poole A |
Year: |
1997 |
Journal: |
EMBO J |
Title: |
The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. |
Volume: |
16 |
Issue: |
9 |
Pages: |
2333-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamasaki S |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
Mincle is an ITAM-coupled activating receptor that senses damaged cells. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1179-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nimmerjahn F |
Year: |
2005 |
Journal: |
Immunity |
Title: |
FcgammaRIV: a novel FcR with distinct IgG subclass specificity. |
Volume: |
23 |
Issue: |
1 |
Pages: |
41-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mancardi DA |
Year: |
2008 |
Journal: |
J Clin Invest |
Title: |
FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammation. |
Volume: |
118 |
Issue: |
11 |
Pages: |
3738-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jakus Z |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Critical but overlapping role of FcgammaRIII and FcgammaRIV in activation of murine neutrophils by immobilized immune complexes. |
Volume: |
180 |
Issue: |
1 |
Pages: |
618-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Syed SN |
Year: |
2009 |
Journal: |
Eur J Immunol |
Title: |
Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a. |
Volume: |
39 |
Issue: |
12 |
Pages: |
3343-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
DiLillo DJ |
Year: |
2014 |
Journal: |
Nat Med |
Title: |
Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo. |
Volume: |
20 |
Issue: |
2 |
Pages: |
143-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Negishi-Koga T |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Immune complexes regulate bone metabolism through FcRγ signalling. |
Volume: |
6 |
|
Pages: |
6637 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hogarth PM |
Year: |
1987 |
Journal: |
Immunogenetics |
Title: |
The mouse Fc receptor for IgG (Ly-17): molecular cloning and specificity. |
Volume: |
26 |
Issue: |
3 |
Pages: |
161-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hibbs ML |
Year: |
1986 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The murine Fc receptor for immunoglobulin: purification, partial amino acid sequence, and isolation of cDNA clones. |
Volume: |
83 |
Issue: |
18 |
Pages: |
6980-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhalerao J |
Year: |
1995 |
Journal: |
J Biol Chem |
Title: |
Molecular cloning, characterization, and genetic mapping of the cDNA coding for a novel secretory protein of mouse. Demonstration of alternative splicing in skin and cartilage. |
Volume: |
270 |
Issue: |
27 |
Pages: |
16385-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sears DW |
Year: |
1990 |
Journal: |
J Immunol |
Title: |
Molecular cloning and expression of the mouse high affinity Fc receptor for IgG. |
Volume: |
144 |
Issue: |
1 |
Pages: |
371-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Osman N |
Year: |
1992 |
Journal: |
J Immunol |
Title: |
Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene. |
Volume: |
148 |
Issue: |
5 |
Pages: |
1570-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quilliam AL |
Year: |
1993 |
Journal: |
Immunology |
Title: |
Biochemical characterization of murine Fc gamma RI. |
Volume: |
78 |
Issue: |
3 |
Pages: |
358-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barnes N |
Year: |
2002 |
Journal: |
Immunity |
Title: |
FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. |
Volume: |
16 |
Issue: |
3 |
Pages: |
379-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ioan-Facsinay A |
Year: |
2002 |
Journal: |
Immunity |
Title: |
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. |
Volume: |
16 |
Issue: |
3 |
Pages: |
391-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou H |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
Microtubule-associated serine/threonine kinase-205 kDa and Fc gamma receptor control IL-12 p40 synthesis and NF-kappa B activation. |
Volume: |
172 |
Issue: |
4 |
Pages: |
2559-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ikegami H |
Year: |
1995 |
Journal: |
J Clin Invest |
Title: |
Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping. |
Volume: |
96 |
Issue: |
4 |
Pages: |
1936-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Vugt MJ |
Year: |
1996 |
Journal: |
Blood |
Title: |
FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo. |
Volume: |
87 |
Issue: |
9 |
Pages: |
3593-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng P |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Expression and secretion of TNF-α in mouse taste buds: a novel function of a specific subset of type II taste cells. |
Volume: |
7 |
Issue: |
8 |
Pages: |
e43140 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Beavis PA |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors. |
Volume: |
110 |
Issue: |
36 |
Pages: |
14711-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gordan S |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity. |
Volume: |
29 |
Issue: |
10 |
Pages: |
3033-3046.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frederico B |
Year: |
2022 |
Journal: |
Dev Cell |
Title: |
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential. |
Volume: |
57 |
Issue: |
16 |
Pages: |
1957-1975.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chikina AS |
Year: |
2020 |
Journal: |
Cell |
Title: |
Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption. |
Volume: |
183 |
Issue: |
2 |
Pages: |
411-428.e16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sahin M |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors. |
Volume: |
38 |
Issue: |
5 |
Pages: |
110303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nimmerjahn F |
Year: |
2005 |
Journal: |
Science |
Title: |
Divergent immunoglobulin g subclass activity through selective Fc receptor binding. |
Volume: |
310 |
Issue: |
5753 |
Pages: |
1510-2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zietara N |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Immunoglobulins drive terminal maturation of splenic dendritic cells. |
Volume: |
110 |
Issue: |
6 |
Pages: |
2282-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bloemendaal FM |
Year: |
2017 |
Journal: |
Gastroenterology |
Title: |
Anti-Tumor Necrosis Factor With a Glyco-Engineered Fc-Region Has Increased Efficacy in Mice With Colitis. |
Volume: |
153 |
Issue: |
5 |
Pages: |
1351-1362.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar V |
Year: |
2006 |
Journal: |
J Clin Invest |
Title: |
Cell-derived anaphylatoxins as key mediators of antibody-dependent type II autoimmunity in mice. |
Volume: |
116 |
Issue: |
2 |
Pages: |
512-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nimmerjahn F |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity. |
Volume: |
104 |
Issue: |
20 |
Pages: |
8433-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baudino L |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice. |
Volume: |
180 |
Issue: |
3 |
Pages: |
1948-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rossi O |
Year: |
2019 |
Journal: |
Immunology |
Title: |
The essential role of complement in antibody-mediated resistance to Salmonella. |
Volume: |
156 |
Issue: |
1 |
Pages: |
69-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Jong JM |
Year: |
2006 |
Journal: |
Mol Immunol |
Title: |
Murine Fc receptors for IgG are redundant in facilitating presentation of immune complex derived antigen to CD8+ T cells in vivo. |
Volume: |
43 |
Issue: |
13 |
Pages: |
2045-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rodriguez W |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
C-reactive protein-mediated suppression of nephrotoxic nephritis: role of macrophages, complement, and Fcgamma receptors. |
Volume: |
178 |
Issue: |
1 |
Pages: |
530-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Dam AD |
Year: |
2017 |
Journal: |
Int J Obes (Lond) |
Title: |
IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bandukwala HS |
Year: |
2007 |
Journal: |
J Exp Med |
Title: |
Signaling through Fc gamma RIII is required for optimal T helper type (Th)2 responses and Th2-mediated airway inflammation. |
Volume: |
204 |
Issue: |
8 |
Pages: |
1875-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
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Year: |
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