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Search results 301 to 373 out of 373 for Tgm6

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Hits by Strain

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Type Details Score
Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Tg(tetO-BRAF*V600E)29Lc/? Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129/Sv * C57BL/6J * FVB * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Nras/Nras Stk11/Stk11 Tg(Tyr-cre/ERT2)13Bos/?
Background: B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nras Cdkn2a Stk11
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(KRT14-rtTA)F42Efu/? Tg(tetO-EDN1,-lacZ)9Mhus/? Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mc1r/Mc1r Tg(KRT14-rtTA)F42Efu/? Tg(tetO-EDN1,-lacZ)9Mhus/? Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf<+> Ezh2/Ezh2<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ezh2/Ezh2<+> Nras/Nras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Tyr-cre/ERT2)13Bos/?
Background: STOCK Tg(Tyr-cre/ERT2)13Bos Gt(ROSA)26Sor/Gt(ROSA)26Sor/Cvrk
Zygosity: cn
Has Mutant Allele: true
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Publication
23123854 | J:189208
First Author: Mitra D
Year: 2012
Journal: Nature
Title: An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.
Volume: 491
Issue: 7424
Pages: 449-53
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Publication
28011934 | J:252348
First Author: Dominguez D
Year: 2017
Journal: J Immunol
Title: Exogenous IL-33 Restores Dendritic Cell Activation and Maturation in Established Cancer.
Volume: 198
Issue: 3
Pages: 1365-1375
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Publication
31471106 | J:282377
First Author: Rivadeneira DB
Year: 2019
Journal: Immunity
Title: Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance.
Volume: 51
Issue: 3
Pages: 548-560.e4
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Publication
33184221 | J:329418
First Author: Infarinato NR
Year: 2020
Journal: Genes Dev
Title: BMP signaling: at the gate between activated melanocyte stem cells and differentiation.
Volume: 34
Issue: 23-24
Pages: 1713-1734
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Publication
25252692 | J:220627
First Author: Burd CE
Year: 2014
Journal: Cancer Discov
Title: Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma.
Volume: 4
Issue: 12
Pages: 1418-29
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Publication
35672316 | J:325350
First Author: Murphy BM
Year: 2022
Journal: Nat Commun
Title: Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.
Volume: 13
Issue: 1
Pages: 3153
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Publication
27135738 | J:239472
First Author: Souroullas GP
Year: 2016
Journal: Nat Med
Title: An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.
Volume: 22
Issue: 6
Pages: 632-40
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Publication
20697345 | J:164588
First Author: Monahan KB
Year: 2010
Journal: Oncogene
Title: Somatic p16(INK4a) loss accelerates melanomagenesis.
Volume: 29
Issue: 43
Pages: 5809-17
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Publication
33086062 | J:306533
First Author: Maitituoheti M
Year: 2020
Journal: Cell Rep
Title: Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.
Volume: 33
Issue: 3
Pages: 108293
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Publication
29993000 | J:265039
First Author: Tokuo H
Year: 2018
Journal: Sci Rep
Title: Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis.
Volume: 8
Issue: 1
Pages: 10449
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Publication
19282848 | J:151023
First Author: Dankort D
Year: 2009
Journal: Nat Genet
Title: Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.
Volume: 41
Issue: 5
Pages: 544-52
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Publication
22039523 | J:179725
First Author: Landrette SF
Year: 2011
Journal: PLoS One
Title: piggyBac transposon somatic mutagenesis with an activated reporter and tracker (PB-SMART) for genetic screens in mice.
Volume: 6
Issue: 10
Pages: e26650
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Publication
29339718 | J:257726
First Author: Parfejevs V
Year: 2018
Journal: Nat Commun
Title: Injury-activated glial cells promote wound healing of the adult skin in mice.
Volume: 9
Issue: 1
Pages: 236
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Publication
22172720 | J:178598
First Author: Damsky WE
Year: 2011
Journal: Cancer Cell
Title: β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas.
Volume: 20
Issue: 6
Pages: 741-54
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Publication
34348144 | J:311103
First Author: Eshiba S
Year: 2021
Journal: Cell Rep
Title: Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi.
Volume: 36
Issue: 5
Pages: 109492
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Publication
27977682 | J:238714
First Author: Pytel D
Year: 2016
Journal: PLoS Genet
Title: PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.
Volume: 12
Issue: 12
Pages: e1006518
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Publication
35267510 | J:327289
 
First Author: Vázquez-Naharro A
Year: 2022
Journal: Cancers (Basel)
Title: Loxl3 Promotes Melanoma Progression and Dissemination Influencing Cell Plasticity and Survival.
Volume: 14
Issue: 5
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Publication
28753606 | J:244004
First Author: Ruiz R
Year: 2017
Journal: PLoS Genet
Title: The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas.
Volume: 13
Issue: 7
Pages: e1006913
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Publication
29490280 | J:271104
First Author: Moore AR
Year: 2018
Journal: Cell Rep
Title: GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma.
Volume: 22
Issue: 9
Pages: 2455-2468
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Publication
32686704 | J:298942
First Author: Tagliatela AC
Year: 2020
Journal: Sci Rep
Title: Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion.
Volume: 10
Issue: 1
Pages: 11958
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Publication
28202513 | J:242087
First Author: Steinberg SM
Year: 2017
Journal: Cancer Res
Title: Myeloid Cells That Impair Immunotherapy Are Restored in Melanomas with Acquired Resistance to BRAF Inhibitors.
Volume: 77
Issue: 7
Pages: 1599-1610
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Publication
30664764 | J:282386
First Author: Cheng WC
Year: 2019
Journal: Nat Immunol
Title: Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle.
Volume: 20
Issue: 2
Pages: 206-217
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Publication
27400148 | J:259419
First Author: Riedel A
Year: 2016
Journal: Nat Immunol
Title: Tumor-induced stromal reprogramming drives lymph node transformation.
Volume: 17
Issue: 9
Pages: 1118-27
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Publication
25673642 | J:224242
First Author: Xie X
Year: 2015
Journal: Cancer Discov
Title: Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma.
Volume: 5
Issue: 4
Pages: 410-23
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Publication
37335131 | J:340270
First Author: Adaku N
Year: 2023
Journal: Cancer Res
Title: Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis.
Volume: 83
Issue: 18
Pages: 3013-3025
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Publication
27775706 | J:240803
First Author: Moynihan KD
Year: 2016
Journal: Nat Med
Title: Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.
Volume: 22
Issue: 12
Pages: 1402-1410
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Publication
33951424 | J:306664
First Author: DeVito NC
Year: 2021
Journal: Cell Rep
Title: Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy.
Volume: 35
Issue: 5
Pages: 109071
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Ezh2/Ezh2<+> Nras/Nras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129S4/SvJae * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
28463229 | J:244758
First Author: Olvedy M
Year: 2017
Journal: J Clin Invest
Title: Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma.
Volume: 127
Issue: 6
Pages: 2310-2325
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Publication
31017901 | J:275837
First Author: Joshi SS
Year: 2019
Journal: PLoS Genet
Title: CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties.
Volume: 15
Issue: 4
Pages: e1008034
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Publication
30905671 | J:275676
First Author: Sullivan MR
Year: 2019
Journal: Cell Metab
Title: Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting.
Volume: 29
Issue: 6
Pages: 1410-1421.e4
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Publication
28053125 | J:240920
First Author: Cain-Hom C
Year: 2017
Journal: Nucleic Acids Res
Title: Efficient mapping of transgene integration sites and local structural changes in Cre transgenic mice using targeted locus amplification.
Volume: 45
Issue: 8
Pages: e62
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Publication
28202614 | J:252719
First Author: Erkes DA
Year: 2017
Journal: J Immunol
Title: Virus-Specific CD8+ T Cells Infiltrate Melanoma Lesions and Retain Function Independently of PD-1 Expression.
Volume: 198
Issue: 7
Pages: 2979-2988
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Publication
27760326 | J:240819
First Author: Kohlhapp FJ
Year: 2016
Journal: Cell Rep
Title: Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.
Volume: 17
Issue: 4
Pages: 957-965
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Publication
31685822 | J:281598
First Author: Sun Q
Year: 2019
Journal: Nat Commun
Title: A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease.
Volume: 10
Issue: 1
Pages: 5023
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Publication
37076619 | J:340038
First Author: Sun Q
Year: 2023
Journal: Nature
Title: Dedifferentiation maintains melanocyte stem cells in a dynamic niche.
Volume: 616
Issue: 7958
Pages: 774-782
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Publication
28486109 | J:242574
First Author: Spranger S
Year: 2017
Journal: Cancer Cell
Title: Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy.
Volume: 31
Issue: 5
Pages: 711-723.e4
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Publication
34939927 | J:318008
   
First Author: Urtatiz O
Year: 2021
Journal: Elife
Title: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma.
Volume: 10
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Publication
- | J:312561
     
First Author: Urtatiz1 O
Year: 2021
Journal: bioRxiv
Title: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma.
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Publication
32066953 | J:292988
First Author: Wang H
Year: 2020
Journal: Nat Immunol
Title: CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Volume: 21
Issue: 3
Pages: 298-308
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Publication
28886380 | J:252491
First Author: Grinberg-Bleyer Y
Year: 2017
Journal: Cell
Title: NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer.
Volume: 170
Issue: 6
Pages: 1096-1108.e13
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Publication
25848750 | J:227784
First Author: Mann MB
Year: 2015
Journal: Nat Genet
Title: Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma.
Volume: 47
Issue: 5
Pages: 486-95
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Publication
29033351 | J:253959
First Author: Köhler C
Year: 2017
Journal: Cell Stem Cell
Title: Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.
Volume: 21
Issue: 5
Pages: 679-693.e6
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Publication
29033353 | J:253978
First Author: Moon H
Year: 2017
Journal: Cell Stem Cell
Title: Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure.
Volume: 21
Issue: 5
Pages: 665-678.e6
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Publication
34473941 | J:324261
First Author: Li MY
Year: 2021
Journal: Dev Cell
Title: UV-induced reduction in Polycomb repression promotes epidermal pigmentation.
Volume: 56
Issue: 18
Pages: 2547-2561.e8
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Publication
30008323 | J:264236
First Author: Zingg D
Year: 2018
Journal: Cancer Cell
Title: EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
Volume: 34
Issue: 1
Pages: 69-84.e14
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Publication
30951662 | J:284490
First Author: Varum S
Year: 2019
Journal: Cell Stem Cell
Title: Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation.
Volume: 24
Issue: 4
Pages: 637-653.e9
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Publication
23332765 | J:193498
First Author: Burd CE
Year: 2013
Journal: Cell
Title: Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.
Volume: 152
Issue: 1-2
Pages: 340-51
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Publication
23454771 | J:196375
First Author: Knight DA
Year: 2013
Journal: J Clin Invest
Title: Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Volume: 123
Issue: 3
Pages: 1371-81
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Publication
31257073 | J:277539
First Author: Lionarons DA
Year: 2019
Journal: Cancer Cell
Title: RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance.
Volume: 36
Issue: 1
Pages: 68-83.e9
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Publication
22573620 | J:185553
First Author: Hari L
Year: 2012
Journal: Development
Title: Temporal control of neural crest lineage generation by Wnt/β-catenin signaling.
Volume: 139
Issue: 12
Pages: 2107-17
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Publication
36131018 | J:335416
First Author: Karras P
Year: 2022
Journal: Nature
Title: A cellular hierarchy in melanoma uncouples growth and metastasis.
Volume: 610
Issue: 7930
Pages: 190-198
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Publication
21663796 | J:173080
First Author: Rabbani P
Year: 2011
Journal: Cell
Title: Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration.
Volume: 145
Issue: 6
Pages: 941-955
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Publication
27341128 | J:240369
First Author: Das SK
Year: 2016
Journal: Oncotarget
Title: Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.
Volume: 7
Issue: 30
Pages: 46848-46861
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Publication
31375534 | J:289994
First Author: Etzerodt A
Year: 2019
Journal: J Exp Med
Title: Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.
Volume: 216
Issue: 10
Pages: 2394-2411
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Publication
34099918 | J:308669
First Author: Jacquelot N
Year: 2021
Journal: Nat Immunol
Title: Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma.
Volume: 22
Issue: 7
Pages: 851-864
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Publication
37516803 | J:339727
First Author: Arumi-Planas M
Year: 2023
Journal: Oncogene
Title: Microenvironmental Snail1-induced immunosuppression promotes melanoma growth.
Volume: 42
Issue: 36
Pages: 2659-2672
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Publication
23436574 | J:196071
First Author: van der Weyden L
Year: 2013
Journal: J Pathol
Title: Cancer of mice and men: old twists and new tails.
Volume: 230
Issue: 1
Pages: 4-16
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Publication
35525247 | J:324929
First Author: Reticker-Flynn NE
Year: 2022
Journal: Cell
Title: Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.
Volume: 185
Issue: 11
Pages: 1924-1942.e23
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Publication
29343435 | J:272341
First Author: Zhao F
Year: 2018
Journal: Immunity
Title: Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization.
Volume: 48
Issue: 1
Pages: 147-160.e7
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Publication
27134165 | J:231435
First Author: Takeo M
Year: 2016
Journal: Cell Rep
Title: EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling.
Volume: 15
Issue: 6
Pages: 1291-302
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Publication
34285232 | J:307921
First Author: Jeong SH
Year: 2021
Journal: Nat Commun
Title: Refractoriness of STING therapy is relieved by AKT inhibitor through effective vascular disruption in tumour.
Volume: 12
Issue: 1
Pages: 4405
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Publication
36150390 | J:330167
First Author: Mandula JK
Year: 2022
Journal: Cancer Cell
Title: Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
Volume: 40
Issue: 10
Pages: 1145-1160.e9
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Publication
37451271 | J:346107
First Author: Meiser P
Year: 2023
Journal: Cancer Cell
Title: A distinct stimulatory cDC1 subpopulation amplifies CD8(+) T cell responses in tumors for protective anti-cancer immunity.
Volume: 41
Issue: 8
Pages: 1498-1515.e10
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Publication
34912121 | J:338087
First Author: Xu Z
Year: 2022
Journal: Nature
Title: Anatomically distinct fibroblast subsets determine skin autoimmune patterns.
Volume: 601
Issue: 7891
Pages: 118-124
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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