Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
sheep |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
pig, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
lemur, mouse |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cat, domestic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock |
|
•
•
•
•
•
|
Publication |
First Author: |
Day C |
Year: |
1977 |
Journal: |
Mouse News Lett |
Title: |
HPRT mobility alteration, Hma. |
Volume: |
57 |
|
Pages: |
10 |
|
•
•
•
•
•
|
Heritable Phenotypic Marker |
Type: |
heritable_phenotypic_marker |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Nesbitt MN |
Year: |
1979 |
Journal: |
Biochem Genet |
Title: |
Isoenzyme pattern of HPRT in murine erythrocytes: control by an autosomal locus. |
Volume: |
17 |
Issue: |
9-10 |
Pages: |
957-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ben-Zur T |
Year: |
1999 |
Journal: |
Genomics |
Title: |
Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25. |
Volume: |
58 |
Issue: |
1 |
Pages: |
102-3 |
|
•
•
•
•
•
|
Allele |
Name: |
HPRT mobility alteration; wild type |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Melton DW |
Year: |
1987 |
|
Title: |
HPRT gene organization and expression |
Volume: |
4 |
|
Pages: |
34-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moore TF |
Year: |
1992 |
Journal: |
Mouse Genome |
Title: |
Failure to detect age-related reactivation at the Hprt locus |
Volume: |
90 |
Issue: |
4 |
Pages: |
687-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuehn MR |
Year: |
1987 |
Journal: |
Nature |
Title: |
A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice. |
Volume: |
326 |
Issue: |
6110 |
Pages: |
295-8 |
|
•
•
•
•
•
|
Allele |
Name: |
cytochrome P450, family 1, subfamily a, polypeptide 2; targeted mutation 1, Daniel W Nebert |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim TM |
Year: |
2008 |
Journal: |
Genesis |
Title: |
High-throughput knock-in coupling gene targeting with the HPRT minigene and Cre-mediated recombination. |
Volume: |
46 |
Issue: |
12 |
Pages: |
732-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vogel M |
Year: |
2019 |
Journal: |
Stem Cells |
Title: |
HPRT and Purine Salvaging Are Critical for Hematopoietic Stem Cell Function. |
Volume: |
37 |
Issue: |
12 |
Pages: |
1606-1614 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson S |
Year: |
1989 |
Journal: |
Cell |
Title: |
Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells. |
Volume: |
56 |
Issue: |
2 |
Pages: |
313-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bol SA |
Year: |
1998 |
Journal: |
Cancer Res |
Title: |
Elevated frequencies of benzo(a)pyrene-induced Hprt mutations in internal tissue of XPA-deficient mice. |
Volume: |
58 |
Issue: |
13 |
Pages: |
2850-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shannon M |
Year: |
1993 |
Journal: |
Biol Reprod |
Title: |
Expression of the Hprt gene during spermatogenesis: implications for sex-chromosome inactivation. |
Volume: |
49 |
Issue: |
4 |
Pages: |
770-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fukagawa T |
Year: |
1999 |
Journal: |
Nucleic Acids Res |
Title: |
The chicken HPRT gene: a counter selectable marker for the DT40 cell line. |
Volume: |
27 |
Issue: |
9 |
Pages: |
1966-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guillot PV |
Year: |
2000 |
Journal: |
Physiol Genomics |
Title: |
Targeting of human eNOS promoter to the Hprt locus of mice leads to tissue-restricted transgene expression. |
Volume: |
2 |
Issue: |
2 |
Pages: |
77-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Isamat M |
Year: |
1988 |
Journal: |
Somat Cell Mol Genet |
Title: |
Characterization, evolutionary relationships, and chromosome location of processed mouse HPRT pseudogene. |
Volume: |
14 |
Issue: |
4 |
Pages: |
359-69 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heaney JD |
Year: |
2004 |
Journal: |
Genomics |
Title: |
Tissue-specific expression of a BAC transgene targeted to the Hprt locus in mouse embryonic stem cells. |
Volume: |
83 |
Issue: |
6 |
Pages: |
1072-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGregor DB |
Year: |
1996 |
Journal: |
Toxicol In Vitro |
Title: |
Mutagenic responses of L5178Y mouse cells at the tk and hprt loci. |
Volume: |
10 |
Issue: |
5 |
Pages: |
643-647 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
218
|
Fragment?: |
false |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Skopek TR |
Year: |
1995 |
Journal: |
Environ Mol Mutagen |
Title: |
Relative sensitivity of the endogenous hprt gene and lacI transgene in ENU-treated Big Blue B6C3F1 mice. |
Volume: |
26 |
Issue: |
1 |
Pages: |
9-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Evans V |
Year: |
2000 |
Journal: |
Physiol Genomics |
Title: |
Targeting the Hprt locus in mice reveals differential regulation of Tie2 gene expression in the endothelium. |
Volume: |
2 |
Issue: |
2 |
Pages: |
67-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Doetschman T |
Year: |
1988 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Targeted mutation of the Hprt gene in mouse embryonic stem cells. |
Volume: |
85 |
Issue: |
22 |
Pages: |
8583-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Palais G |
Year: |
2009 |
Journal: |
Physiol Genomics |
Title: |
Targeted transgenesis at the HPRT locus: an efficient strategy to achieve tightly controlled in vivo conditional expression with the tet system. |
Volume: |
37 |
Issue: |
2 |
Pages: |
140-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lock LF |
Year: |
1986 |
Journal: |
Mol Cell Biol |
Title: |
Methylation of the mouse hprt gene differs on the active and inactive X chromosomes. |
Volume: |
6 |
Issue: |
3 |
Pages: |
914-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pravtcheva DD |
Year: |
1994 |
Journal: |
J Exp Zool |
Title: |
Mosaic expression of an Hprt transgene integrated in a region of Y heterochromatin. |
Volume: |
268 |
Issue: |
6 |
Pages: |
452-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Selfridge J |
Year: |
1992 |
Journal: |
Somat Cell Mol Genet |
Title: |
Gene targeting using a mouse HPRT minigene/HPRT-deficient embryonic stem cell system: inactivation of the mouse ERCC-1 gene. |
Volume: |
18 |
Issue: |
4 |
Pages: |
325-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Doetschman T |
Year: |
1987 |
Journal: |
Nature |
Title: |
Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. |
Volume: |
330 |
Issue: |
6148 |
Pages: |
576-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsuda H |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines. |
Volume: |
42 |
Issue: |
3 |
Pages: |
413-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Masson W |
Year: |
1996 |
Journal: |
Mamm Genome |
Title: |
The use of compound heterozygotes and Hprt selection to analyze X-linked mottled alleles associated with prenatal lethality. |
Volume: |
7 |
Issue: |
7 |
Pages: |
486-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Palella TD |
Year: |
1989 |
Journal: |
Gene |
Title: |
Expression of human HPRT mRNA in brains of mice infected with a recombinant herpes simplex virus-1 vector. |
Volume: |
80 |
Issue: |
1 |
Pages: |
137-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skopek TR |
Year: |
1992 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mutational spectrum at the Hprt locus in splenic T cells of B6C3F1 mice exposed to N-ethyl-N-nitrosourea. |
Volume: |
89 |
Issue: |
17 |
Pages: |
7866-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Minami T |
Year: |
2003 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Ets motifs are necessary for endothelial cell-specific expression of a 723-bp Tie-2 promoter/enhancer in Hprt targeted transgenic mice. |
Volume: |
23 |
Issue: |
11 |
Pages: |
2041-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hosoya T |
Year: |
2022 |
Journal: |
J Am Soc Nephrol |
Title: |
Xanthine Oxidoreductase Inhibitors Suppress the Onset of Exercise-Induced AKI in High HPRT Activity Urat1-Uox Double Knockout Mice. |
Volume: |
33 |
Issue: |
2 |
Pages: |
326-341 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guibinga GH |
Year: |
2013 |
Journal: |
Hum Mol Genet |
Title: |
Deficiency of the purine metabolic gene HPRT dysregulates microRNA-17 family cluster and guanine-based cellular functions: a role for EPAC in Lesch-Nyhan syndrome. |
Volume: |
22 |
Issue: |
22 |
Pages: |
4502-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dobrovolsky VN |
Year: |
2003 |
Journal: |
Mutagenesis |
Title: |
Pms2 deficiency results in increased mutation in the Hprt gene but not the Tk gene of Tk(+/-) transgenic mice. |
Volume: |
18 |
Issue: |
4 |
Pages: |
365-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Walker VE |
Year: |
1993 |
Journal: |
Mutat Res |
Title: |
A mouse model for the study of in vivo mutational spectra: sequence specificity of ethylene oxide at the hprt locus. |
Volume: |
288 |
Issue: |
1 |
Pages: |
151-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cvetkovic B |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
Appropriate tissue- and cell-specific expression of a single copy human angiotensinogen transgene specifically targeted upstream of the HPRT locus by homologous recombination. |
Volume: |
275 |
Issue: |
2 |
Pages: |
1073-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sturm K |
Year: |
1999 |
Journal: |
Int J Dev Biol |
Title: |
Pgk1 and Hprt gene activity in the peri-implantation mouse embryo is influenced by the parental origin of the X-chromosome. |
Volume: |
43 |
Issue: |
1 |
Pages: |
69-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reid LH |
Year: |
1990 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells. |
Volume: |
87 |
Issue: |
11 |
Pages: |
4299-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vivian JL |
Year: |
1999 |
Journal: |
Biotechniques |
Title: |
Temporal, spatial and tissue-specific expression of a myogenin-lacZ transgene targeted to the Hprt locus in mice. |
Volume: |
27 |
Issue: |
1 |
Pages: |
154-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kushi A |
Year: |
1998 |
Journal: |
Mamm Genome |
Title: |
Generation of mutant mice with large chromosomal deletion by use of irradiated ES cells--analysis of large deletion around hprt locus of ES cell. |
Volume: |
9 |
Issue: |
4 |
Pages: |
269-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magin TM |
Year: |
1992 |
Journal: |
Gene |
Title: |
A position- and orientation-dependent element in the first intron is required for expression of the mouse hprt gene in embryonic stem cells. |
Volume: |
122 |
Issue: |
2 |
Pages: |
289-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lyon MF |
Year: |
1987 |
Journal: |
Cytogenet Cell Genet |
Title: |
Localization of the Hprt locus by in situ hybridization and distribution of loci on the mouse X-chromosome. |
Volume: |
44 |
Issue: |
2-3 |
Pages: |
163-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klarmann B |
Year: |
1995 |
Journal: |
Int J Radiat Biol |
Title: |
Mutant frequency at the H-2K class 1 and HPRT genes in T lymphocytes from the X-ray-exposed mouse. |
Volume: |
67 |
Issue: |
4 |
Pages: |
421-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dobrovolsky VN |
Year: |
1999 |
Journal: |
Environ Mol Mutagen |
Title: |
Molecular analysis of in vivo mutations induced by N-ethyl-N-nitrosourea in the autosomal Tk and the X-linked Hprt genes of mouse lymphocytes. |
Volume: |
34 |
Issue: |
1 |
Pages: |
30-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Noda A |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Creation of Mice Bearing a Partial Duplication of HPRT Gene Marked with a GFP Gene and Detection of Revertant Cells In Situ as GFP-Positive Somatic Cells. |
Volume: |
10 |
Issue: |
8 |
Pages: |
e0136041 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diaz M |
Year: |
2003 |
Journal: |
Mol Cancer Res |
Title: |
Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta. |
Volume: |
1 |
Issue: |
11 |
Pages: |
836-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
George AM |
Year: |
1994 |
Journal: |
Genomics |
Title: |
Analysis of Mnk, the murine homologue of the locus for Menkes disease, in normal and mottled (Mo) mice. |
Volume: |
22 |
Issue: |
1 |
Pages: |
27-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
McEwan C |
Year: |
2003 |
Journal: |
Transgenic Res |
Title: |
A simple genotyping assay for the Hprt null allele in mice produced from the HM-1 and E14TG2a mouse embryonic stem cell lines. |
Volume: |
12 |
Issue: |
4 |
Pages: |
519-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Francke U |
Year: |
1979 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Assignment of the gene for cytoplasmic superoxide dismutase (Sod-1) to a region of chromosome 16 and of Hprt to a region of the X chromosome in the mouse. |
Volume: |
76 |
Issue: |
10 |
Pages: |
5230-3 |
|
•
•
•
•
•
|
Allele |
Name: |
hemoglobin beta chain complex; targeted mutation 1.1, Thomas M Ryan |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Law ML |
Year: |
1984 |
Journal: |
Cytogenet Cell Genet |
Title: |
Genes coding for ouabain resistance (OUBR) and HPRT are syntenic in the mouse genome. (Abstracts of meeting presentations: Human gene mapping 7, Los Angeles Conference (1983) Seventh International Workshop on Human Gene Mapping) |
Volume: |
37 (1-4) |
|
Pages: |
518 (Abstr.) (399-616) |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Huo Y |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Humanized Mouse Model of Cooley's Anemia. |
Volume: |
284 |
Issue: |
8 |
Pages: |
4889-96 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hbb/Hbb<+> |
Background: |
involves: C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hbb/Hbb |
Background: |
involves: C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Sauer J |
Year: |
1999 |
Journal: |
J Bacteriol |
Title: |
Expression of the Methanobacterium thermoautotrophicum hpt gene, encoding hypoxanthine (Guanine) phosphoribosyltransferase, in Escherichia coli. |
Volume: |
181 |
Issue: |
6 |
Pages: |
1958-62 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entryconsists of the hypoxanthine/guanine phosphoribosyltransferase (HPRT) and HPRT-like proteins. HPRT catalyses a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis []. HPRT-like proteins may catalyse a purine salvage reaction, the substrate is unknown. |
|
•
•
•
•
•
|
Publication |
First Author: |
Ratcliff R |
Year: |
1993 |
Journal: |
Nat Genet |
Title: |
Production of a severe cystic fibrosis mutation in mice by gene targeting. |
Volume: |
4 |
Issue: |
1 |
Pages: |
35-41 |
|
•
•
•
•
•
|
Allele |
Name: |
inhibin beta-A; targeted mutation 1, Martin M Matzuk |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
rhomboid 5 homolog 1; targeted mutation 1.1, Andrew JH Smith |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Allele |
Name: |
hemoglobin alpha chain complex; targeted mutation 1.1, Andrew JH Smith |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Allele |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Frederic Jaisser |
Allele Type: |
Targeted |
Attribute String: |
Inducible, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Frederic Jaisser |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inducible, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Allele |
Name: |
keratin 18; targeted mutation 1, Thomas M Magin |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
PMS1 homolog 1, mismatch repair system component; targeted mutation 1, Michael Liskay |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant stock |
|
•
•
•
•
•
|
Strain |
Attribute String: |
Not specified |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Tomaszewski J |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Essential roles of inhibin beta A in mouse epididymal coiling. |
Volume: |
104 |
Issue: |
27 |
Pages: |
11322-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Davis AA |
Year: |
2000 |
Journal: |
Mol Cell Neurosci |
Title: |
Activin A promotes progenitor differentiation into photoreceptors in rodent retina. |
Volume: |
15 |
Issue: |
1 |
Pages: |
11-21 |
|
•
•
•
•
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Publication |
First Author: |
Moore CS |
Year: |
1998 |
Journal: |
Dev Dyn |
Title: |
Expression and function of activin beta A during mouse cardiac cushion tissue formation. |
Volume: |
212 |
Issue: |
4 |
Pages: |
548-62 |
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•
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Allele |
Name: |
follistatin; targeted mutation 1, Martin M Matzuk |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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•
•
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•
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Allele |
Name: |
rhomboid 5 homolog 1; targeted mutation 2.1, Andrew JH Smith |
Allele Type: |
Targeted |
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•
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•
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Allele |
Name: |
huntingtin; targeted mutation 3, Peter J Detloff |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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•
•
•
•
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Allele |
Name: |
hemoglobin alpha chain complex; targeted mutation 2.1, Andrew JH Smith |
Allele Type: |
Targeted |
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•
•
•
•
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Allele |
Name: |
cystic fibrosis transmembrane conductance regulator; targeted mutation 1, University of Cambridge |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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•
•
•
•
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Allele |
Name: |
leucine rich repeat containing 17; targeted mutation 1, Nigel Killeen |
Allele Type: |
Targeted |
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•
•
•
•
•
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Genotype |
Symbol: |
Inhba/Inhba |
Background: |
either: (129S/SvEv-Inhba) or (involves: 129S7/SvEvBrd * C57BL/6) |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Genotype |
Symbol: |
Inhba/Inhba |
Background: |
involves: 129S7/SvEvBrd |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rhbdf1/Hba/Rhbdf1/Hba |
Background: |
involves: 129P2/OlaHsd * C57BL/6 * CBA |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rhbdf1/Hba/Rhbdf1/Hba |
Background: |
involves: 129P2/OlaHsd * C57BL/6 * CBA |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Inhba/Inhba<+> |
Background: |
B6.129S7-Inhba |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Inhba/Inhba |
Background: |
involves: 129S7/SvEvBrd * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Publication |
First Author: |
Stacey A |
Year: |
1994 |
Journal: |
Mol Cell Biol |
Title: |
Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice. |
Volume: |
14 |
Issue: |
2 |
Pages: |
1009-16 |
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•
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•
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MP Term |
|
•
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•
|
MP Term |
|
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•
|
Publication |
First Author: |
Wu CL |
Year: |
1993 |
Journal: |
Nat Genet |
Title: |
Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice. |
Volume: |
3 |
Issue: |
3 |
Pages: |
235-40 |
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•
•
•
•
•
|
Publication |
First Author: |
Jinnah HA |
Year: |
1992 |
Journal: |
Mol Cell Neurosci |
Title: |
Localization of hypoxanthine-guanine phosphoribosyltransferase mRNA in the mouse brain by in situ hybridization. |
Volume: |
3 |
Issue: |
1 |
Pages: |
64-78 |
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•
•
•
•
|
Publication |
First Author: |
Pickell L |
Year: |
2011 |
Journal: |
Mamm Genome |
Title: |
Targeted insertion of two Mthfr promoters in mice reveals temporal- and tissue-specific regulation. |
Volume: |
22 |
Issue: |
11-12 |
Pages: |
635-47 |
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