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Search results 201 to 291 out of 291 for Il2rb

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Type Details Score
Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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DO Term
DOID:0111997 | immunodeficiency 63
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Allele
Il3<em2Smoc> | MGI:7290494
Name: interleukin 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428969 | C57BL/6JSmoc-Il2rb<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Il2rb<m1Btlr> | MGI:6269414
Name: interleukin 2 receptor, beta chain; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6269415 | C57BL/6J-Il2rb<m1Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Genotype
Genotype
Symbol: Il2rb/Il2rb
Background: C57BL/6J-Il2rb
Zygosity: hm
Has Mutant Allele: true
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Publication
36446385 | J:340910
First Author: Masle-Farquhar E
Year: 2022
Journal: Immunity
Title: STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2D(hi) CD8(+) T cell dysregulation and accumulation.
Volume: 55
Issue: 12
Pages: 2386-2404.e8
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Allele
Tg(Vpreb1-IL2RB)F133Ilm | MGI:5505492
Name: transgene insertion F133, Inga-Lill Martensson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:5505501 | C57BL/6J-Tg(Vpreb1-IL2RB)F133Ilm/H
Attribute String: mutant strain, transgenic, coisogenic
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Publication
12672078 | J:199513
First Author: Licence S
Year: 2003
Journal: Eur J Immunol
Title: The VpreB1 enhancer drives developmental stage-specific gene expression in vivo.
Volume: 33
Issue: 4
Pages: 1117-26
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Publication
7946053 | -
First Author: Leonard WJ
Year: 1994
Journal: Curr Opin Immunol
Title: The defective gene in X-linked severe combined immunodeficiency encodes a shared interleukin receptor subunit: implications for cytokine pleiotropy and redundancy.
Volume: 6
Issue: 4
Pages: 631-5
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Protein Domain
IPR003531 | Hempt_rcpt_S_F1_CS
Type: Conserved_site
Description: A number of receptors for lymphokines, hematopoietic growth factors andgrowth hormone-related molecules have been found to share a common bindingdomain. These receptors are designated as hematopoietin receptors []andthe corresponding ligands as hematopoietins. Further, hematopoietins have beensubdivided into two major structural groups: Large/long and small/shorthematopoietins.One subset of individual receptor chains that are part of receptor complexes for small hematopoietins are structurally related such that their extracellular parts strictly contain the 200 amino-acids hematopoietin domain (duplicated in IL-3/-5/GM-CSF beta chain receptors KH97/AIC2B and AIC2A). They define a structural subgroup containing the following chains: Interleukin-2 receptor beta chain (IL2RB), Interleukin-2 receptor common gamma chain (IL2RG), Interleukin-3 receptor beta chain (AIC2A), Interleukin-3/-5/GM-CSF receptor common beta chain (KH97/AIC2B), Interleukin-4 receptor alpha chain (IL4RA), Interleukin-7 receptor alpha chain (IL7RA), Interleukin-9 receptor alpha chain (IL9RA). A schematic representation of the structure of these receptors is shown below: +----------------------------------------xxxxxxx---------------------------+| C C C C Extracellular XXXXXXX Cytoplasmic |+-|-|-------|--|-------------------------xxxxxxx---------------------------+| | | | Transmembrane+-+ +--+IL4RA, IL7RA and IL9RA are specific alpha chain receptors for IL-4, IL-7and IL-9 respectively, whereas IL2RB is common to IL-2 and IL-15 (IL2RA andIL15RA are not members of the hematopoietin receptor superfamily). IL2RG ispart of IL-2, IL-15, IL-7, IL-9 and IL-4 form I receptor complexes [].KH97/AIC2B chain is part of GM-CSF, IL-3 and IL-5 receptor complexes and inthe mouse, AIC2B can be substituted by AIC2A, an IL-3 specific beta chainreceptor []. Together with either IL13RA1 or IL13RA2, IL4RA is also partof the IL-13 receptor complex for which IL-4 can compete with IL-13 (IL-4receptor complex form II) [].
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Publication
8552669 | J:30615
First Author: Hilton DJ
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor.
Volume: 93
Issue: 1
Pages: 497-501
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Publication
1913811 | -
First Author: Nicola NA
Year: 1991
Journal: Cell
Title: Subunit promiscuity among hemopoietic growth factor receptors.
Volume: 67
Issue: 1
Pages: 1-4
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Protein
Q01114
Organism: Mus musculus/domesticus
Length: 468  
Fragment?: false
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Protein
Q9JHX3
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
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Protein
P16297
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
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Protein
Q78PA5
Organism: Mus musculus/domesticus
Length: 468  
Fragment?: false
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Protein
B0QZX1
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
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Protein
Q8CBU1
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
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Protein
Q8C2G1
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
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Protein
Q2M2M3
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Protein
Q3TA82
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: true
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Protein
Q3UBS8
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
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Protein
B7ZD65
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Protein
A2AVE0
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
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Protein
Q3TAI3
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
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Protein
A2AGH5
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
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Protein
Q8R308
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
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Protein
Q3TEQ2
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
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Protein
Q4KKX7
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
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Protein
Q6PEU8
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein
P16872
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
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Protein
P26954
Organism: Mus musculus/domesticus
Length: 878  
Fragment?: false
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Protein
P26955
Organism: Mus musculus/domesticus
Length: 896  
Fragment?: false
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Protein
P16382
Organism: Mus musculus/domesticus
Length: 810  
Fragment?: false
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Protein
P34902
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: false
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Protein
A2VCP1
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: true
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Protein
Q3U2T6
Organism: Mus musculus/domesticus
Length: 896  
Fragment?: false
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Protein
Q3U905
Organism: Mus musculus/domesticus
Length: 810  
Fragment?: false
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Protein
Q3V057
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
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Protein
Q3UPA9
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: false
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Protein
A0A2R8VK01
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
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Protein
Q5FW78
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
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Protein
Q3U3Z0
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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Protein
Q3U3P4
Organism: Mus musculus/domesticus
Length: 790  
Fragment?: true
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Protein
Q3U2L4
Organism: Mus musculus/domesticus
Length: 652  
Fragment?: true
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Protein
Q8C9W4
Organism: Mus musculus/domesticus
Length: 456  
Fragment?: true
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Protein
A0A2I3BRC2
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
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Protein
W8DLM5
Organism: Mus musculus/domesticus
Length: 782  
Fragment?: true
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Protein
Q3U1Z1
Organism: Mus musculus/domesticus
Length: 769  
Fragment?: false
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Protein
Q3U1W0
Organism: Mus musculus/domesticus
Length: 878  
Fragment?: false
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Protein
A0A2R8VHE8
Organism: Mus musculus/domesticus
Length: 769  
Fragment?: false
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Protein
Q3TB34
Organism: Mus musculus/domesticus
Length: 670  
Fragment?: true
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Protein
Q544A9
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: true
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Protein
Q3UE66
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
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Protein
Q8QZX9
Organism: Mus musculus/domesticus
Length: 896  
Fragment?: false
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Protein
Q3U241
Organism: Mus musculus/domesticus
Length: 878  
Fragment?: false
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Publication
1400369 | -
First Author: Boulay JL
Year: 1992
Journal: J Biol Chem
Title: The interleukin-4-related lymphokines and their binding to hematopoietin receptors.
Volume: 267
Issue: 29
Pages: 20525-8
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Protein
P48356
Organism: Mus musculus/domesticus
Length: 1162  
Fragment?: false
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Protein
Q640Q2
Organism: Mus musculus/domesticus
Length: 818  
Fragment?: false
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Protein
Q3UNU8
Organism: Mus musculus/domesticus
Length: 892  
Fragment?: false
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Protein
Q3US58
Organism: Mus musculus/domesticus
Length: 894  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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