Expression was detected in a mosaic pattern in the heterozygous female. Absorptive cells in the villus portion were aggregates of either positive or negative expression.
Expression was detected in patches in the crypts. The crypts were composed of both positive and negative staining cells. Long patches were noted along the villus projection.
Expression was detected in patches in the crypts. The crypts were composed of both positive and negative staining cells. Long patches were noted along the villus projection.
Expression was strong in the intestinal epithelium, but absent from the nonepithelial tissues of the Tunica Submucosa, Tunica Muscularis and Tunica Serosa.
Disorganization of the neuronal network with abnormal aggregates surrounded by enlarged negative spaces was exacerbated. Negative spaces were larger than in beta1-null mutant.
Expression was localized to the plasma membrane of the proximal tubular segments. The basolateral surface exhibits slight immunostaining, but more intense reactivity was evident on the apical surface.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and stage IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and stage IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and stage IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and stage IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and stage IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and stage IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and stage IV tubules.
Section in situ hybridization indicated enriched expression in early proximal tubule (marker gene). Expression was detected in stage III and stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to early proximal tubule of stage IV tubules.
Expression was weak throughout the skeletal and dental mesenchyme. Expression was intense in a few layers of dental mesenchyme cells directly underlying the dental epithelium.
Expression was retained in the early suprachiasmatic nucleus unilaterally in mice displaying partial Six3 deletion. Loss of expression was only observed in regions lacking Six3.
Authors state the immature superior cervical ganglion was similar to wild type embryos, and clearly separated from the stellate (inferior cervical) ganglion.
Normal expression was detected in superior cervical ganglion axonal projections along the internal carotid artery. However, mutants demonstrated markedly deficient projections along the external carotid artery.
Expression was lacking in 2 of 5 gonads examined. (In another 2 there was faint staining that was not convincingly higher than the background staining.)
Expression downregulated indicating anterior truncation of forebrain. Authors report expression was variably affected, ranging from no difference to complete loss in the most affected embryos.
Expression was detected in most of the prismatic or cubic cells in the endocardium of the atrioventricular cushions. The endocardial cells were uniformly labeled.
Expression was detected in most of the prismatic or cubic cells in the endocardium of the atrioventricular cushions. The endocardial cells were uniformly labeled.
The decreased number of immunopositive cells in the conotruncal cushions of the mutant was due to a reduced number of migrating GFP+ neural crest cells.
Expression was detected in endothelial cells of blood capillaries in the dental papilla subjacent to the odontoblasts and in microvessels inside the dental mesenchyme.
Expression was detected in endothelial cells of blood capillaries in the dental papilla subjacent to the odontoblasts and in microvessels inside the dental mesenchyme.
Expression was detected in endothelial cells of blood capillaries in the dental papilla subjacent to the odontoblasts and in microvessels inside the dental mesenchyme.
Expression in pericytes in the vasculature, i.e. in cells tightly surrounding the endothelium, but not in endothelial cells. Higher magnification was shown in the inset.
Expression was detected in blood vessels throughout the periosteum of the tibia, the surrounding tissue and in the marrow cavity. The cartilage is free of blood vessels.
Expression was detected in the brain. Phenotypic abnormalities of some vessels were noted. The density of capillaries was reduced and the width increased.
Expression was detected in capillaries in the neocortical area. Reduced numbers of capillary sprouting sites, increased diameter and aberrant branchings were noted.
Expression was detected in capillaries in the amygdaloid region. Reduced numbers of capillary sprouting sites, increased diameter and aberrant branchings were noted.
This mutant has regions of avascularity and vessels were poorly formed and density was sparse with large avascular spaces between the blood vessels and some were thickened.
This mutant has regions of avascularity and vessels were poorly formed and density was sparse with large avascular spaces between the blood vessels and some were thickened.
Sample was from the ganglionic eminence region. Staining indicated abnormal, distended blood vessel morphologies as well as disrupted contacts with perivascular neuroepithelial cells.
Sample was from the ganglionic eminence region. Staining indicated abnormal, distended blood vessel morphologies as well as disrupted contacts with perivascular neuroepithelial cells.
Expression was detected in the diencephalon and lamina terminalis, but the region between the diencephalon and the lamina terminalis, the mammillary region, had light, punctate staining.
Expression is in the trunk. The author describes this expression as in the pronephros. Mesonephros was chosen to be consistent with the anatomical dictionary at this stage.
Expression is restricted to the luminal aspect. The authors use the term pronephros. Mesonephros was chosen to be consistent with the anatomical dictionary at this stage.
Expression was detected on the apical side of the coelomic epithelial cells and mesonephric tubules. An immunopositive reaction was found between the coelomic epithelium and underlying mesonephric tubules.
Immunopositive axons were observed projecting from the olfactory epithelium towards the olfactory bulbs. There was no obvious difference in the appearance of staining in the mutant.
The expression domain showed a border at the proximal part of the developing digits. Expression was not visible in the region of the phalange cartilage.
Expression was detected in layer VI projection neurons in the motor cortex. A significant decrease in immunopositive cell density was noted compared with wild type.
Expression was detected in layer VI projection neurons in the motor cortex. A significant decrease in immunopositive cell density was noted compared with wild type.
