Expression is in all regions of the lens except for a narrow region in the inner cortex where a decrease in signal was detected in the absence of pre-treatment with Triton X-100.
Higher expression in the inner cortical fiber cells where it was associated with fiber cell membranes and remained associated with the fiber cell membranes even after they lost their nuclei.
Increased staining was observed compared with wild type, particularly in the cytoplasm of epithelial-like cells. In some lenses, distinct nuclear Ctnnb1 was also detectable, particularly in the epithelioid cells in the fiber compartment.
Expression was most intensely localized at the anterior ends of the lens fibers, adjacent to the epithelial layer, with reactivity decreasing more posteriorly. There was partial overlap with Tob2 in some of the cytoplasmic Tob2+ granules.
Expressed throughout the kidney in mesenchymal cells in both the medullary interstitium and the nephrogenic zone, and at ureteric bud tips, except for condensing mesenchymal structures where expression was downregulated.
There was no significant difference in the expression domain in the mutant. The mesenchyme in the mutant displayed a split phenotype as a consequence of the ectopic ureteric buds.
Expression was detected in all layers of the cortical neuroepithelium, from the ventricular zone to the cortical plate. In interphase cells within the ventricular zone, immunostaining appeared to be symmetrically distributed.
Strong immunoreactivity was detected in a significant number of cells in the ventricular zone. Immunostaining in most of the dividing cells (88.3%) was symmetric. 11.7% of the cells showed asymmetric staining.
Expression was detected in the ventricular zone of the lateral cortex but ceased at the boundary of the cortex and lateral ganglionic eminence. Boundary does not coincide with the cortico-striatal sulcus but extends over lateromost field of the LGE VZ.
Expression was detected in the ventricular zone of the lateral cortex but ceased at the boundary of the cortex and lateral ganglionic eminence. Boundary does not coincide with the cortico-striatal sulcus but extends over lateromost field of the LGE VZ.
Expression was detected in the ventricular zone of the lateral cortex but ceased at the boundary of the cortex and lateral ganglionic eminence. Boundary does not coincide with the cortico-striatal sulcus but extends over lateromost field of the LGE VZ.
Expression was detected in the ventricular zone of the lateral cortex but ceased at the boundary of the cortex and lateral ganglionic eminence. Boundary does not coincide with the cortico-striatal sulcus but extends over lateromost field of the LGE VZ.
Expressed in both the nuclei of differentiating Tubb3+ neuroblast and most progenitors Tubb3- cells, which is composed of gliogenic and bipotent radial glial cells (75%) and basal progenitors (25%). Expression was absent in the mitotic condensed chromosomes.
The frequency of the cells reentering the cell cycle is given as the ratio of BrdU and Ki67 double-positive cells over the total number of BrdU-positive cells. This ratio was significantly reduced in the miR-9-2/3 double-mutant ventricular zone.
The percentage of Neurog2/BrdU double-positive progenitors was only 5.4% of the total Neurog2+ population, a fraction well below the proportion of positive progenitors expected to be in S-phase if Neurog2 was homogeneously expressed throughout the cell cycle (25.4%).
There was a gradient of expression in the dorsolateral prostate lobe with dense staining in the distal duct tips fading gradually to a faint staining in the more proximal ducts.
There was a gradient of expression in the dorsolateral prostate lobe with dense staining in the distal duct tips fading gradually to a faint staining in the more proximal ducts.
Expression was detected at a more posterior level in the bending neural folds and in cells migrating lateral to the neural folds, which appear to be hindbrain neural crest.
Expression was detected throughout the rostrocaudal extent of R3 and R5 neuroepithelium, most prominent dorsally and at the rhombomere boundaries. Neuroepithelium expression was also detected in a continuum from R1 into the forebrain.
Expression extended over the caudal two thirds of the midbrain. Expression was not throughout the thickness of the neuroepithelium, but in single neuroblasts on the pial surface of the midbrain.
Expressed exclusively in endothelial cells. Expression was easily detected in the endothelial nuclei of vessels undergoing arterial remodeling, but quantification revealed levels to be lower than the nonremodeling capillary vessels (Fig. 2B').
Expression was detected at a more posterior level in the bending neural folds and in cells migrating lateral to the neural folds, which appear to be hindbrain neural crest.
The staining observed with this probe generally appeared to be non-specific. However, the staining was strongest in the renal interstitium, suggesting that there might be some specific staining in this tissue.
Expression in the adult organ was detected in a sparse population of thin tubules in the outer medulla that does not colocalize with LTL. This expression was thought to be a segment of the loop of Henle.
Wnt4 signal was strongest at the junction where it contacts the ovary and two lines of signal in the mesonephric mesenchyme running medial to and parallel to the nephric duct and paramesonephric duct.
Expression is present in the urethral groove. (Originally this result was annotated to a male-specific term, but as the specimen was not sexed, it is likely the data annotator intended to use a non-gender specific term.)
Expression is present in the urethral groove. (Originally this result was annotated to a male-specific term, but as the specimen was not sexed, it is likely the data annotator intended to use a non-gender specific term.)
Expression is present in the urethral groove. (Originally this result was annotated to a male-specific term, but as the specimen was not sexed, it is likely the data annotator intended to use a non-gender specific term.)
Expression is present in the urethral groove. (Originally this result was annotated to a male-specific term, but as the specimen was not sexed, it is likely the data annotator intended to use a non-gender specific term.)
Strongly expressed in the cortex, in uninduced mesenchymal cells in the nephrogenic zone and in ureteric bud tips. A weaker signal was detected in mesenchymal cells in the medulla and around the ureter.
Expressed throughout the kidney in mesenchymal cells in both the medullary interstitium and the nephrogenic zone, and at ureteric bud tips, except for condensing mesenchymal structures where expression was downregulated.
High expression was detected in lymphatic endothelial progenitor cells upon their exit from the cardinal veins at E11.5. Less ellipticity of the nucleus was noted in the mutant compared with control.
Expression was detected in the enteric nervous system (ENS) neuronal precursors in the gut. Proliferation of these neuronal precursors was lower in the heterozygous animal compared to wild type as indicated by BrdU incorporation.
Expression was detected in several neural crest cell populations, including cells within the wall of the midgut that are enteric nervous system precursors, future spinal ganglia, and future sympathetic ganglia surrounding the aorta.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY, and 5-HT (in the stomach) and CGRP, Calb1, Nos1 and VIP (in the small intestine). Co-expression was seen with all.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with all.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with all.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP, Calb1 and Nos1 and partial co-expression with Npy and CHaT.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP, Calb1 and Nos1 and partial co-expression with Npy and CHaT.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and CGRP and partial co-expression with Calb1, Nos1, Npy and CHaT.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP, Calb1 and NPY and partial co-expression with Nos1 and CHaT.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP and NPY and partial co-expression with Calb1, Nos1 and CHaT.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP and NPY and partial co-expression with Calb1, Nos1 and CHaT.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY, and 5-HT (in the stomach) and CGRP, Calb1, Nos1 and VIP (in the small intestine). Co-expression was seen with Th, partial co-expression with 5-HT and no co-expression with the rest.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, no co-expression with CGRP, and partial-coexpression with the rest.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with NPY and partial co-expression with the rest.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and NPY and partial co-expression with the rest.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and NPY and partial co-expression with the rest.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with CGRP and NPY and partial co-expression with the rest.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and NPY and partial co-expression with the rest.
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, CGRP, Calb1, Nos1, NPY, 5-HT and VIP (in the stomach). Partial co-expression was seen with with TH, Calb1, and NPY and no co-expression with the rest.
Goosecoid expression was restricted within patches that lay mainly between, rather than within, the mesenchymal condensations destined to give rise to skeletal elements. Expression was seen within the region of the developing ankle and wrist.
Goosecoid expression was restricted within patches that lay mainly between, rather than within, the mesenchymal condensations destined to give rise to skeletal elements. Expression was seen within the region of the developing ankle and wrist.
Expression was located in an area corresponding to the posterior side of the wrist-forming region, and in the wrist itself, and in the distal joints of radius and ulna.
High expression was noted in the distal zeugopod surrounding and including the developing distal growth plates. Highest expression was restricted to distal end of both zeugopod bones and most proximal wrist bones.
Expression was more specific and restricted to the posterior regions of the limb and extended more prominently into the proximal zeugopod to include the olecranon. Expression was excluded from the developing distal growth plates.
Expression in gonocytes was underwent nuclear to cytoplasmic translocation at E18.5 The number of cells with nuclear only expression was low, while cytoplasmic only or cytoplasmic and nuclear increased.
Expression in gonocytes was underwent nuclear to cytoplasmic translocation at E18.5 The translocation is correlated with expression of Gfra1. The majority of gonocytes with cytoplasmic expression only also expressed Gfra1.
Hybridization signal was detected on most types of germ cell. Signal was detectable in meiotic and post-meiotic cells within the adluminal compartment. However, the intensity of signal was considerable lower than in the basally-located cells.
Expression was detected throughout the entire width of the neural plate and tube. Expression was more intense where tube was not yet closed. Signal was stronger near the lumen of the tube.
Expression was detected throughout the entire width of the neural plate and tube. Expression was more intense where tube was not yet closed. Signal was stronger near the lumen of the tube.
Expression was detected in the right ventricle and the forming ventricular septum. Transcripts localized to the outer proliferative compact layer of the ventricular myocardium and to a much lesser extent in the trabeculae.
The pattern of labelling does not differ greatly from the previous stage. The number of neurofilament-positive cells or fibers appears increased. Description of the pattern was summarized in Table 2.
Strong immunoreactivity was seen in a subset of fibrocytes in the spiral ligament mostly near the border with the bony shell of the cochlea. A thread-like staining pattern suggested that staining was localized on the cell processes.
Expression was seen in yolk sac mesoderm in patches of cells lining the perimeter of the blood islands. Morphology of the cells indicate that expression is mainly confined to endothelial cell precursors.
Expression was detected in the starburst amacrine cells that had migrated to the appropriate cell layers as in wild type. There were regions where the somata were clumped in the mutant.
Immunostained cells were observed in the ganglion cell layer (many of which are likely to be displaced amacrines). Immunreactivity was observed in bright puncta, frequently positioned adjacent to the nucleus and the apical dendrite.
Expression was detected in postmitotic retinal ganglion cells (RGC's) in the ventrotemporal retina. Co-label with Zic2 was seen in ipsilateral RGC's. Few of the RGC's were co-labeled with EdU when injected at E11.
Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Zic2 was seen in ipsilateral RGC's. Few of the RGC's were co-labeled with EdU when injected at E12.
Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Zic2 was seen in ipsilateral RGC's. The number of RGC's co-labeled with EdU was higher when injected at E13 than when injected at previous ages.
Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Zic2 was seen in ipsilateral RGC's. The number of RGC's co-labeled with EdU was highest when injected at E14 than when injected at previous ages.
Expression was detected in ipsilateral retinal ganglion cells (RGC's) in the ventrotemporal retina. Co-label was seen with Isl1, which labels all postmitotic RGC's. Few of the RGC's were co-labeled with EdU when injected at E11.
Expression was detected in ipsilateral retinal ganglion cells in the ventrotemporal retina. Co-label was seen with Isl1, which labels all postmitotic RGC's. Few of the RGC's were co-labeled with EdU when injected at E12.
Expression was detected in ipsilateral retinal ganglion cells in the ventrotemporal retina. The number of RGC's co-labeled with EdU when injected at E14 was similar between samples taken at E15.5 and E16.5.
Expression was detected in ipsilateral retinal ganglion cells in the ventrotemporal retina. The number of RGC's co-labeled with EdU when injected at E15 was similar to when injected at E14.
Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. The number of RGC's co-labeled with EdU when injected at E14 was similar between samples taken at E15.5 and E16.5.
Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. The number of RGC's co-labeled with EdU when injected at E15 was similar to when injected at E14.
Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Isl2 was seen in contralateral RGC's. Some RGC's were co-labeled with EdU when injected at E13.
Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Isl2 was seen in contralateral RGC's. The number of RGC's co-labeled with EdU was higher when injected at E14 than when injected at E13.
Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Isl2 was seen in contralateral RGC's. RGC proliferation, as determined by co-label with EdU, during late development was substantial until E15 and decreased thereafter.
Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Isl2 was seen in contralateral RGC's. RGC proliferation, as determined by co-label with EdU, was decreased when injected at E16 than when injected at previous ages.
Expression was detected in contralateral retinal ganglion cells (RGC's) in the ventrotemporal retina. Co-label with Isl1 was seen in postmitotic RGC's. Some contralateral RGC's were co-labeled with EdU when injected at E13.
Expression was detected in contralateral retinal ganglion cells (RGC's) in the ventrotemporal retina. Co-label with Isl1 was seen in postmitotic RGC's. More contralateral RGC's were co-labeled with EdU when injected at E14 than when injected at E13.
Expression was detected in contralateral retinal ganglion cells (RGC's) in the ventrotemporal retina. Co-label with Isl1 was seen in postmitotic RGC's. More contralateral RGC's were co-labeled with EdU when injected at E15 than when injected at E14.
Expression was detected in contralateral retinal ganglion cells (RGC's) in the ventrotemporal retina. Co-label with Isl1 was seen in postmitotic RGC's. The number of contralateral RGC's co-labeled with EdU when injected at E16 sharply decreased.
Expression was detected in ipsilateral retinal ganglion cells in the ventrotemporal retina. The number of RGC's co-labeled with EdU was similar when injected at E14 than when injected at E13.
Expression was detected in ipsilateral retinal ganglion cells in the ventrotemporal retina. The number of RGC's co-labeled with EdU was similar when injected at E15 than when injected at E14.
Expression was detected in ipsilateral retinal ganglion cells in the ventrotemporal retina. The number of RGC's co-labeled with EdU was sharply lower when injected at E16 than when injected at E15.
Expressed in the dermal lymphatic sprouts, which were dilated and failed to migrate toward the midline of the embryo. There was an increased number of cells in lymphatic vessels.
Expression was restricted to the caudal part of the ventral thalamus, the dorsal midline of the dorsal thalamus and pretectum, with a mediolateral expansion on the dorsal surface of the caudal pretectum.
Expression was restricted to the caudal part of the ventral thalamus, the dorsal midline of the dorsal thalamus and pretectum, with a mediolateral expansion on the dorsal surface of the caudal pretectum.
Wnt-3 was expressed in a single domain coinciding with the dorsal thalamus. Expression was strongest in ventricular cells of the dorsal midline, from where it extended ventrally. Thus, expression was strongest dorsally.
Expression was detected in the early embryonic ventral lateral geniculate nucleus, the reticular thalamic nucleus and the zona incerta. Expression was conserved primarily along the anterioposterior axis of the lateral geniculate nucleus.
Expression was detected in the early embryonic ventral lateral geniculate nucleus, the reticular thalamic nucleus and the zona incerta. Expression was conserved primarily along the anterioposterior axis of the lateral geniculate nucleus.
Expression was detected in the early embryonic ventral lateral geniculate nucleus, the reticular thalamic nucleus and the zona incerta. Expression was conserved primarily along the anterioposterior axis of the lateral geniculate nucleus.
Sections were taken at different coronal levels of embryonic ventral lateral geniculate nucleus. Expression was seen at level 2 (this section), but not 3. Expression was seen in the external medullary lamina at levels 1 and 2.
Sections were taken at different coronal levels of embryonic ventral lateral geniculate nucleus. Expression was seen at levels 2 (this section) and 3, but not 1. Expression was seen in the external medullary lamina at levels 2 and 3.
Sections were taken at different coronal levels of embryonic ventral lateral geniculate nucleus. Expression was seen at levels 2 and 3 (this section), but not 1. Expression was seen in the external medullary lamina at levels 2 and 3.
Sections were taken at different coronal levels of embryonic ventral lateral geniculate nucleus. Expression was seen at levels 2 (this section) and 3, but not 1. Expression was seen in the external medullary lamina at levels 2 and 3.
Sections were taken at different coronal levels of embryonic ventral lateral geniculate nucleus. Expression was seen at levels 2 and 3 (this section), but not 1. Expression was seen in the external medullary lamina at levels 2 and 3.
