Expression in pancreatic progenitor cells of dorsal pancreatic bud at E10.5 coinciding with Pdx1 and Ngn3 expression in scattered cells throughout pancreatic epithelium.
Expression in pancreatic progenitor cells of dorsal pancreatic bud at E10.5 coinciding with Ptf1a and Pdx1 in scattered cells throughout pancreatic epithelium.
The tip-restricted expression pattern of expression persists through successive branching and growth of the pancreatic tree. All Cpa1-positive cells co-express Pdx1 and constitute a subset of Pdx1-positive epithelial cells (representing 13.6% of total Pdx1-positive cells at E13.5).
The tip-restricted expression pattern of expression persists through successive branching and growth of the pancreatic tree. Expression levels vary among tip cells. All Cpa1-positive cells co-express Pdx1 and constitute a subset of Pdx1-positive epithelial cells (representing 16.8% of total Pdx1-positive cells at E14.5).
By E12.5, there were well-formed primary branches in the pancreas, and Cpa1 expression was largely restricted to the branching tips. All Cpa1-positive cells co-express Pdx1 and constitute a subset of Pdx1-positive epithelial cells (representing 13.3% of total Pdx1-positive cells at E12.5).