Type
Details
Score
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716430
Age:
postnatal week 4
Note:
Expression at the chondro-osseous junction between the growth plate cartilage and metaphysis of the proximal tibia. Staining overlapped with cathepsin B-positive (Ctsb) cells, which identified the cells as septoclasts/perivascular cells.
Specimen Label:
1f
Detected:
true
Specimen Num:
1
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716430
Age:
postnatal week 4
Note:
Expression at the chondro-osseous junction between the growth plate cartilage and metaphysis of the proximal tibia. Staining overlapped with DBA lectin-positive cells, which identified the cells as septoclasts/perivascular cells.
Specimen Label:
1g
Detected:
true
Specimen Num:
2
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Absent
Sex:
Male
Emaps:
EMAPS:3789628
Stage:
TS28
Assay Id:
MGI:7716435
Age:
postnatal week 4
Note:
Staining did not overlap with Lgals3 (MAC-2)-positive osteoclasts of the proximal tibia.
Specimen Label:
2a
Detected:
false
Specimen Num:
1
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Absent
Sex:
Male
Emaps:
EMAPS:3789628
Stage:
TS28
Assay Id:
MGI:7716430
Age:
postnatal week 4
Note:
Expression did not overlap with BSA lectin stained endothelial cells of the proximal tibia.
Specimen Label:
2b
Detected:
false
Specimen Num:
3
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Absent
Sex:
Male
Emaps:
EMAPS:3789628
Stage:
TS28
Assay Id:
MGI:7716428
Age:
postnatal week 4
Note:
Staining did not overlap with alkaline phosphatase-stained osteoblasts of the proximal tibia.
Specimen Label:
2c
Detected:
false
Specimen Num:
2
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716437
Age:
postnatal week 4
Note:
At low-magnification immunoelectron microscopy, thin and long cell processes with immunoreactivity extended along the longitudinal septa toward the transverse septa.
Specimen Label:
3a
Detected:
true
Specimen Num:
1
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716437
Age:
postnatal week 4
Note:
At the junctional area between the longitudinal and transverse septa, the end portion of the immunopositive cell processes possessed microvillus-like processes that intruded into the cartilage matrix of the transverse septa. Immunoreactive cells were rich in mitochondria. The immunoreactivity was specially condensed on the mitochondrial outer membrane as well as throughout the entire cytoplasm.
Specimen Label:
3b
Detected:
true
Specimen Num:
2
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716428
Age:
postnatal week 4
Note:
Immunoreactivity in septoclasts/perivascular cells in the chondro-osseous junction of the proximal tibia did not overlap with Ppara.
Specimen Label:
5a
Detected:
true
Specimen Num:
3
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716428
Age:
postnatal week 4
Note:
Immunoreactivity in septoclasts/perivascular cells in the chondro-osseous junction of the proximal tibia co-localized with Pparb/d.
Specimen Label:
5b
Detected:
true
Specimen Num:
4
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716428
Age:
postnatal week 4
Note:
Immunoreactivity in septoclasts/perivascular cells in the chondro-osseous junction of the proximal tibia did not overlap with Pparg.
Specimen Label:
5c
Detected:
true
Specimen Num:
5
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Not Specified
Emaps:
EMAPS:3789627
Pattern:
Regionally restricted
Stage:
TS27
Assay Id:
MGI:7716428
Age:
postnatal newborn
Note:
In the growing growth plate of newborn (postnatal week 0) mice, many immunoreactive cells were observed at the chondro-osseus junction. The immunoreactive cells possessed long processes directed toward the bottom of the growth plate cartilage.
Specimen Label:
6c
Detected:
true
Specimen Num:
7
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716428
Age:
postnatal week 1
Note:
In the tibial growth plate at suckling stages (postnatal week 1), immunopositive cells at the chondro-osseus junction were increased in number; and the distance between the immunoreactive cells was shorter than that in newborns. The number of septoclasts increased in number from E16 to postnatal week 1-2.
Specimen Label:
6d
Detected:
true
Specimen Num:
8
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716428
Age:
postnatal week 2
Note:
In the tibial growth plate at suckling stages (postnatal week 2), immunopositive cells at the chondro-osseus junction were increased in number; and the distance between the immunoreactive cells was shorter than that in newborns. The number of septoclasts increased in number from E16 to postnatal week 1-2, and the peak number was reached at postnatal week 2.
Specimen Label:
6e
Detected:
true
Specimen Num:
9
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716428
Age:
postnatal week 3
Note:
In the tibial growth plate of young mice after weaning (postnatal week 3), the distribution of immunopositive cells at the chondro-osseus junction was very similar to that at postnatal week 1.
Specimen Label:
6f
Detected:
true
Specimen Num:
10
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716428
Age:
postnatal week 4
Note:
In the tibial growth plate of young mice after weaning (postnatal week 4), the distribution of immunopositive cells at the chondro-osseus junction was very similar to that at postnatal week 1.
Specimen Label:
6g
Detected:
true
Specimen Num:
11
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716428
Age:
postnatal week 9
Note:
In the growth plate at sub-adult stage (postnatal week 9), numerous immunopositive cells were arranged along the chondro-osseus junction with a distribution pattern similar to that at the postnatal week 3 or 4 stage, but a decrease in number of immunoreactive cells with a distribution at wider distances from one another was clearly observed. The number of septoclasts at postnatal week 9 decreased to about 40% of the number found at postnatal week 2.
Specimen Label:
6h
Detected:
true
Specimen Num:
12
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Not Specified
Stage:
TS28
Assay Id:
MGI:7716435
Age:
postnatal week 4
Note:
Septoclasts at postnatal week 4 had several long processes that elongated toward the transverse septa.
Specimen Label:
8a
Detected:
true
Specimen Num:
2
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Not Specified
Stage:
TS28
Assay Id:
MGI:7716435
Age:
postnatal week 4
Note:
A number of short (approximately 3 um in length) spines from the septoclast apexes were observed.
Specimen Label:
8b
Detected:
true
Specimen Num:
3
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Not Specified
Stage:
TS28
Assay Id:
MGI:7716435
Age:
postnatal week 9
Note:
In postnatal week 9 mice, immunopositive septoclasts were smaller than those of postnatal week 4 mice and there were fewer cell processes.
Specimen Label:
8c
Detected:
true
Specimen Num:
4
•
•
•
•
•
GXD Expression
Probe:
MGI:7715247
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Not Specified
Stage:
TS28
Assay Id:
MGI:7716435
Age:
postnatal week 9
Note:
Short (approximately 1 um) spines extended from the septoclast apexes to the transverse septa.
Specimen Label:
8d
Detected:
true
Specimen Num:
5
•
•
•
•
•
GXD Expression
Probe:
MGI:7715256
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:1914228
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716440
Age:
postnatal week 4
Note:
Staining co-localized with Fabp5 in septoclasts/perivascular cells in the chondro-osseous junction of the proximal tibia.
Specimen Label:
5b
Detected:
true
Specimen Num:
1
•
•
•
•
•
GXD Expression
Probe:
MGI:7715256
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Regionally restricted
Stage:
TS28
Assay Id:
MGI:7716440
Age:
postnatal week 4
Note:
Staining co-localized with Fabp5 in septoclasts/perivascular cells in the chondro-osseous junction of the proximal tibia.
Specimen Label:
5b
Detected:
true
Specimen Num:
1
•
•
•
•
•
GXD Expression
Probe:
MGI:7715250
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Not Specified
Emaps:
EMAPS:3550524
Pattern:
Regionally restricted
Stage:
TS24
Assay Id:
MGI:7716431
Age:
embryonic day 16.5
Note:
Double immunostaining for Fabp5 and cathepsin B (Ctsb), cells showing co-localization of both proteins were observed in the growth plate.
Specimen Label:
6b
Detected:
true
Specimen Num:
2
•
•
•
•
•
GXD Expression
Probe:
MGI:7715252
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:1914228
Pattern:
Not Specified
Stage:
TS28
Assay Id:
MGI:7716436
Age:
postnatal week 4
Note:
Lgals3 (MAC-2) is a marker for osteoclasts. Staining did not overlap with Fabp5 in the proximal tibia.
Specimen Label:
2a
Detected:
true
Specimen Num:
1
•
•
•
•
•
GXD Expression
Probe:
MGI:7715252
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Present
Sex:
Male
Emaps:
EMAPS:3789628
Pattern:
Not Specified
Stage:
TS28
Assay Id:
MGI:7716436
Age:
postnatal week 4
Note:
Lgals3 (MAC-2) is a marker for osteoclasts. Staining did not overlap with Fabp5 in the proximal tibia.
Specimen Label:
2a
Detected:
true
Specimen Num:
1
•
•
•
•
•
GXD Expression
Probe:
MGI:7715254
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Absent
Sex:
Male
Emaps:
EMAPS:3789628
Stage:
TS28
Assay Id:
MGI:7716439
Age:
postnatal week 4
Note:
Staining did not overlap with Fabp5 in septoclasts/perivascular cells in the chondro-osseous junction of the proximal tibia.
Specimen Label:
5a
Detected:
false
Specimen Num:
1
•
•
•
•
•
GXD Expression
Probe:
MGI:7715258
Assay Type:
Immunohistochemistry
Annotation Date:
2024-09-10
Strength:
Absent
Sex:
Male
Emaps:
EMAPS:3789628
Stage:
TS28
Assay Id:
MGI:7716441
Age:
postnatal week 4
Note:
Staining did not overlap with Fabp5 in septoclasts/perivascular cells in the chondro-osseous junction of the proximal tibia.
Specimen Label:
5c
Detected:
false
Specimen Num:
1
•
•
•
•
•
