Expression was detected in the ventricular zone. There was a gap in the expression domain that coincided with the Pax2 domain in an adjacent section. More rostrally, expression was adjacent to a weaker Pax2 domain.
In Pax2 mutants, the gap, which is normallly devoid of Shh expression is lost, so that the Shh-expressing regions at the preoptic area and the ventral hypothalamus join together and there is no longer an interruption in Shh expression along the A-P axis.
In Pax2 mutants, the gap, which is normallly devoid of Shh expression is lost, so that the Shh-expressing regions at the preoptic area and the ventral hypothalamus join together and there is no longer an interruption in Shh expression along the A-P axis.
