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Search results 3501 to 3576 out of 3576 for Pax6

Category restricted to GXDExpression (x)

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Categories

Category: GXDExpression
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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:5646162
Assay Type: Immunohistochemistry
Annotation Date: 2017-12-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6099125
Age: postnatal adult
Image: 2I
Note: Expression clearly co-localized with Pax6 in amacrine cells.
Specimen Label: 2I
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:5543388
Assay Type: Immunohistochemistry
Annotation Date: 2014-02-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5543503
Age: postnatal day 0
Note: Co-expression with Pax6 was detected in most cortical progenitors.
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2676172
Assay Type: Immunohistochemistry
Annotation Date: 2003-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:2676233
Age: embryonic day 10.5
Image: 1G,1I
Note: Gap in expression of Pax6 and Nkx2.1 expands.
Specimen Label: 1G,1I
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2676172
Assay Type: Immunohistochemistry
Annotation Date: 2003-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691016
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:2676233
Age: embryonic day 9.5
Image: 3A
Note: Expression of Pax6 and Nkx2.1 form a distinct border.
Specimen Label: 3A
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:6436314
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6436562
Age: embryonic day 12.5
Note: Expression co-localized with that of Pax6 within dorsal telencephalic vesicles.
Specimen Label: E12.5 not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6343360
Assay Type: RNA in situ
Annotation Date: 2019-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6343379
Age: embryonic day 8.5
Note: Authors report ectopic expression in dorsal forebrain of Pax6 heterogygotes.
Specimen Label: Pax+/- E8.5 not shown
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5646162
Assay Type: Immunohistochemistry
Annotation Date: 2017-12-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6099125
Age: postnatal day 4
Image: 2G
Note: Authors state expression restricted similar to Pax6 patterns.
Specimen Label: 2G
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:5646162
Assay Type: Immunohistochemistry
Annotation Date: 2017-12-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6099125
Age: postnatal day 7
Image: 2H
Note: Expression clearly co-localized with Pax6 in amacrine cells.
Specimen Label: 2H
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:5646162
Assay Type: Immunohistochemistry
Annotation Date: 2017-12-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6099125
Age: postnatal adult
Image: 2I
Note: Expression clearly co-localized with Pax6 in amacrine cells.
Specimen Label: 2I
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:2152925
Assay Type: RNA in situ
Annotation Date: 2001-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654014
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2153749
Age: embryonic day 9.0
Image: 2E
Note: Expression resembled that of Pax6 (see assay MGI:2153750).
Specimen Label: 2E
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6437483
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6437503
Age: embryonic day 18.5
Note: Expression in Merkel cells, co-localizing with Pax6 expression.
Specimen Label: 2H/I
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6358644
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358676
Age: embryonic day 18.5
Image: 5B'
Note: In Pax6 mutants, the expression domain was shifted and restricted rostrally.
Specimen Label: 5B'
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5009297
Assay Type: RNA in situ
Annotation Date: 2011-06-29
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5009298
Age: embryonic day 14.5
Image: 6A
Note: Expression is diminished in the Pax6 mutant forebrain, but remains appropriately patterned.
Specimen Label: 6A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:7486579
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7486584
Age: embryonic day 18.5
Image: 4F
Note: Disproportionate reduction in number of expressing neurons compared to wild type and Pax6 single mutant.
Specimen Label: 4F
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5317435
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Non-Uniform
Stage: TS21
Assay Id: MGI:6293891
Age: embryonic day 13.5
Image: S2D/F
Note: Expression was increased in the peripheral retinal pigmented epithelium of the Pax6 cKO compared to control.
Specimen Label: S2D/F
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:1346822
Assay Type: RNA in situ
Annotation Date: 1999-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1349177
Age: embryonic day 10.5
Image: 5C E10.5 En2
Note: There is a rostral mesencephalic region where neither Pax6 or En2 is expressed.
Specimen Label: 5C E10.5 En2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1331403
Assay Type: RNA in situ
Annotation Date: 2013-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5490759
Age: embryonic day 12.5
Image: 2A
Note: Expression was detected in the pretectum. Expression overlapped with Pax6 at the caudal limits.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7336054
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3667221
Stage: TS21
Assay Id: MGI:7336061
Age: embryonic day 13.5
Image: 5A''
Note: Expression not co-localized with Pax6 in rhombic lip and beginning of subpial stream.
Specimen Label: 5A''
Detected: false
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:2152925
Assay Type: RNA in situ
Annotation Date: 2001-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1680017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2153746
Age: embryonic day 10.5
Image: 3C
Note: Expression in the olfactory placodes. Expression is the same as Pax6 (see assay MGI:2153747).
Specimen Label: 3C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7432421
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7432601
Age: embryonic day 10.5
Note: Expressed in the p3 domain ventral to the motor neuron progenitor domain (low Pax6 expression).
Specimen Label: 5C +/+ E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2152925
Assay Type: RNA in situ
Annotation Date: 2001-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614014
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2153749
Age: embryonic day 9.0
Image: 2E
Note: Expression in the pre-tectum. Expression resembled that of Pax6 (see assay MGI:2153750).
Specimen Label: 2E
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6153996
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7428954
Age: embryonic day 18.5
Image: 4G WT
Note: Expression was detected in intermediate progenitor cells; co-expression with Pax6 was noted in transitional cell type.
Specimen Label: 4G WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6437483
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3279328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6437503
Age: postnatal day 4
Note: Expression in Merkel cells in outer root sheath of hair follicle, co-localizing with Pax6 expression.
Specimen Label: 2K/L
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:2150169
Assay Type: Immunohistochemistry
Annotation Date: 2001-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:2150330
Age: embryonic day 16.5
Image: 1E
Note: Expression of GSH2 and PAX6 marks the boundary between the LGE and cortical VZ.
Specimen Label: 1E
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2676172
Assay Type: Immunohistochemistry
Annotation Date: 2003-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:2676233
Age: embryonic day 9.5
Image: 1A,1C
Note: Expression of Pax6 and Nkx2.1 forms a boundary in the ventral telencephalon.
Specimen Label: 1A,1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6693485
Assay Type: RNA in situ
Annotation Date: 2021-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6693512
Age: embryonic day 12.5
Image: 4I
Note: Expressed in the ventral telencephalon, forming a sharp crossrepressive boundary with Pax6 at the dorsal-ventral border.
Specimen Label: 4I
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7432421
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7432601
Age: embryonic day 12.5
Note: Expressed in the p3 domain ventral to the motor neuron progenitor domain (low Pax6 expression).
Specimen Label: 5C +/+ E12.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1930393
Assay Type: RNA in situ
Annotation Date: 2023-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757921
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7432878
Age: embryonic day 13.5
Note: Expressed in a region dorsal to Nkx2-2-expressing cells, also overlapped a region of low Pax6 expression.
Specimen Label: 5D
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6436314
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6436562
Age: embryonic day 14.5
Image: 1C
Note: Expression restricted to ventricular zone co-localized with that of Pax6 within dorsal telencephalic vesicles.
Specimen Label: 1C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3763264
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3560828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7491839
Age: postnatal
Image: S6A control
Note: Expression within glomerular layer in population of periglomerular neurons, non-overlapping with Pax6 expression.
Specimen Label: S6A control
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:7341461
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3521222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7341499
Age: embryonic day 14.5
Image: 1D
Note: Coexpressed with Pax6 in granule cells in the external granule cell layer.
Specimen Label: 1D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7341469
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7341507
Age: embryonic day 13.5
Image: S2B
Note: Some cells coexpressed with Pax6 in the external granule cell layer.
Specimen Label: S2B
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5543388
Assay Type: Immunohistochemistry
Annotation Date: 2014-02-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5543503
Age: embryonic day 12.5
Image: 3D/F
Note: Expression was detected in dividing cortical progenitors. Co-expression with Pax6 was detected in most cortical progenitors.
Specimen Label: 3D/F
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7524696
Assay Type: RNA in situ
Annotation Date: 2023-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7524725
Age: embryonic day 12.5
Image: 7H
Note: Domain continues caudally to putative reticular nucleus. Domain expressing Lhx1, Isl1 and Pax6 but not Lhx5.
Specimen Label: 7H
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:6360659
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360729
Age: embryonic day 14.5
Image: 3J
Note: Expression was detected in V0 interneurons. There was some co-expression with Pax6 positive interneurons.
Specimen Label: 3J
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6360657
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360730
Age: embryonic day 14.5
Image: 3M
Note: Expression was detected in ventral V0 interneurons. There was some co-expression with Pax6 positive interneurons.
Specimen Label: 3M
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6356547
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360726
Age: embryonic day 14.5
Image: 3A
Note: Expression was detected in V2a interneurons. There was no co-expression with Pax6 positive interneurons.
Specimen Label: 3A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6360657
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360730
Age: embryonic day 14.5
Image: 4A
Note: Expression was detected in ventral V0 interneurons. There was some co-expression with Pax6 positive interneurons.
Specimen Label: 4A
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5014292
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6360698
Age: postnatal day 25
Image: S1M
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true into adulthood.
Specimen Label: S1M
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6358643
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358675
Age: embryonic day 18.5
Image: 4D'
Note: In Pax6 mutants, the domain of expression expands rostrally to cover the entire rostrocaudal axis of the neocortex.
Specimen Label: 4D'
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6358640
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3525727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6358650
Age: postnatal day 0
Image: 2D
Note: The rostral domain of expression in the wild type cortex exhibits a rostral restriction in Pax6 mutants.
Specimen Label: 2D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:2676482
Assay Type: RNA in situ
Annotation Date: 2003-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:2676606
Age: embryonic day 9.5
Image: 1J
Note: Size of expression domain not altered compared to wild-type. Gap between En1 and Pax6 domains is reduced.
Specimen Label: 1J
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7336054
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7336061
Age: embryonic day 13.5
Image: 5A
Note: Expression predomininantly in nuclear transitory zone; not co-localized with Pax6 expression in rhombic lip and beginning of subpial stream.
Specimen Label: 5A
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:6437484
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3539028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6437506
Age: postnatal day 4
Note: Expression within dermal matrix or inner root sheath of hair follicles from body skin. No overlap with Pax6 expression.
Specimen Label: S1B/C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7461445
Age: embryonic day 11.5
Image: 2L
Note: Expressed in differentiating cells in the mantle zone of the ventral telencephalon, in regions where Pax6 had no expression.
Specimen Label: 2L
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:6437484
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3279228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6437506
Age: postnatal day 4
Note: Expression within dermal matrix or inner root sheath of hair follicles from body skin. No overlap with Pax6 expression.
Specimen Label: S1B/C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6356547
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360726
Age: embryonic day 14.5
Image: 5G
Note: In the mutant, there were cells co-expressing Vsx2 and Pax6 and occasionally cells co-expressing Gata3 and Vsx2.
Specimen Label: 5G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5014292
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6360698
Age: embryonic day 13.5
Image: S1A
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1A
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5014292
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6360698
Age: embryonic day 15.5
Image: S1D
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1D
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5014292
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757725
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6360698
Age: embryonic day 17.5
Image: S1G
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1G
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5014292
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6360698
Age: postnatal day 4
Image: S1J
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1J
Detected: true
Specimen Num: 7
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6358640
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3525627
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6358650
Age: postnatal day 0
Image: 2D
Note: The rostral domain of expression in the wild type cortex exhibits a rostral restriction in Pax6 mutants.
Specimen Label: 2D
Detected: true
Specimen Num: 4
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•
•
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GXD Expression
GXD Expression
Probe: MGI:6358641
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358673
Age: embryonic day 18.5
Image: 3B'
Note: In Pax6 mutant, the boundary between strong and weak layer 5 expression is shifted rostrally. The domain of strong expression in layers 2/3 was absent throughout the neocortex.
Specimen Label: 3B'
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6358639
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358672
Age: embryonic day 18.5
Image: 3D'
Note: In Pax6 mutants, the rostral domain is essentially absent, and high levels of expression continue to the rostral pole of the neocortex.
Specimen Label: 3D'
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6358642
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358674
Age: embryonic day 18.5
Image: 4B'
Note: In Pax6 mutants, expression constricted rostrally, and there was virtually no expression detected in any layers in the caudal half of the neocortex.
Specimen Label: 4B'
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6358645
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358677
Age: embryonic day 18.5
Image: 5D'
Note: In Pax6 mutants a domain of lower expression was not evident, but a small domain of reduced expression was apparent and restricted to a more rostral position.
Specimen Label: 5D'
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7314968
Assay Type: RNA in situ
Annotation Date: 2022-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7314984
Age: embryonic day 13.5
Image: 2A
Note: Variable levels of let-7d expression within Pax6-expressing progenitors along apical-basal axis of Pax6 domain. Higher levels of expression in basal region compared to those located more apically.
Specimen Label: 2A
Detected: true
Specimen Num: 21
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•
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GXD Expression
GXD Expression
 
Probe: MGI:5707367
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5707612
Age: embryonic day 18.0
Note: Expression deeper in the cerebellar anlage and inner granule cell layer co-expressed Pax6. There was no co-expression with Pax6 in the rhombic lip.
Specimen Label: 3A
Detected: true
Specimen Num: 1
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•
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GXD Expression
GXD Expression
 
Probe: MGI:5707367
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5707612
Age: embryonic day 18.0
Note: Expression deeper in the cerebellar anlage and inner granule cell layer co-expressed Pax6. There was no co-expression with Pax6 in the rhombic lip.
Specimen Label: 3C
Detected: true
Specimen Num: 3
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•
•
•
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GXD Expression
GXD Expression
Probe: MGI:2150169
Assay Type: Immunohistochemistry
Annotation Date: 2003-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:2676238
Age: embryonic day 10.5
Image: 1H,1I
Note: Expressed in gap in expression of Pax6 and Nkx2.1 expands, partially overlapping with Pax6 expression, expanded more ventrally into Nkx2.1-positive domain.
Specimen Label: 1H,1I
Detected: true
Specimen Num: 2
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•
•
•
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GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7461456
Age: embryonic day 9.5
Image: 4B/C
Note: Expressed in a narrower region, extending from the floorplate to the roofplate, whose alar domain overlaps a central portion of the diencephalic domain of Pax6 expression.
Specimen Label: 4B/C
Detected: true
Specimen Num: 1
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•
•
•
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GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7461445
Age: embryonic day 8.5
Image: 1D
Note: Expressed throughout much of the diencephalon, with strongest expression in alar regions overlapping the middle of the diencephalic domain of Pax6 expression (summarized in Fig 1M).
Specimen Label: 1D
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7461445
Age: embryonic day 8.5
Image: 1E
Note: Expressed throughout much of the diencephalon, with strongest expression in alar regions overlapping the middle of the diencephalic domain of Pax6 expression (summarized in Fig 1M).
Specimen Label: 1E
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7434439
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3521627
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7434448
Age: postnatal day 0
Image: 1D
Note: Coexpressed with Pax6 in the outer most layers of the external granule cell layer, limited to 1-2 cell layers from the meninges.
Specimen Label: 1D
Detected: true
Specimen Num: 4
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•
•
•
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GXD Expression
GXD Expression
Probe: MGI:1331403
Assay Type: RNA in situ
Annotation Date: 2013-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5490759
Age: embryonic day 12.5
Image: 2A
Note: Expression was detected in the ventral thalamus. Expression overlapped with both Pax6 and Dlx2 at their caudal edges. Expression ended at the ventral/dorsal thalamus boundary.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7524695
Assay Type: RNA in situ
Annotation Date: 2023-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7524724
Age: embryonic day 12.5
Image: 7E
Note: At more caudal level, thalamocortical axon bundle does not express Lhx5. Domain expressing Lhx1, Isl1 and Pax6 but not Lhx5. Expression in putative ventral lateral geniculate nucleus.
Specimen Label: 7E
Detected: true
Specimen Num: 14
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7524694
Assay Type: RNA in situ
Annotation Date: 2023-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7524723
Age: embryonic day 12.5
Image: 7B
Note: At more caudal level, thalamocortical axon bundle does not express Lhx1. Domain expressing Lhx1, Isl1 and Pax6 but not Lhx5. Expression in putative ventral lateral geniculate nucleus.
Specimen Label: 7B
Detected: true
Specimen Num: 14
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6360651
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360727
Age: embryonic day 14.5
Image: 5F
Note: In mutants, expression was detected in interneurons, but there was no co-expression with Pax6 interneurons. Some cells co-expressed Gata3 and Vsx2.
Specimen Label: 5F
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6293890
Assay Type: RNA in situ
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293896
Age: embryonic day 13.5
Image: 1C Proximal Control
Note: There was a spatial dose-dependent inverse relationship between Pax6 and Sox9, with a significant negative correlation between the mRNA levels. A central to peripheral gradient was noted for Sox9 transcripts.
Specimen Label: 1C Proximal Control
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6293890
Assay Type: RNA in situ
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293896
Age: embryonic day 13.5
Image: 1C Middle Control
Note: There was a spatial dose-dependent inverse relationship between Pax6 and Sox9, with a significant negative correlation between the mRNA levels. A central to peripheral gradient was noted for Sox9 transcripts.
Specimen Label: 1C Middle Control
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6293890
Assay Type: RNA in situ
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293896
Age: embryonic day 13.5
Image: 1C Distal Control
Note: There was a spatial dose-dependent inverse relationship between Pax6 and Sox9, with a significant negative correlation between the mRNA levels. A central to peripheral gradient was noted for Sox9 transcripts.
Specimen Label: 1C Distal Control
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7286347
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7286370
Age: embryonic day 14.5
Image: 2D/D'
Note: Expression was abnormal in the cortex and showed no obvious decrease on the pallial side of the pallial-subpallial boundary. Expression in subpallium continued across the boundary deep into the lateral cortex where they now overlapped high Pax6 expression.
Specimen Label: 2D/D'
Detected: true
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7461445
Age: embryonic day 8.5
Image: 1F
Note: Expressed throughout much of the diencephalon, with strongest expression in alar regions overlapping the middle of the diencephalic domain of Pax6 expression. No expression in the telencephalon (summarized in Fig 1M).
Specimen Label: 1F
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6360651
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360727
Age: embryonic day 14.5
Image: 3D
Note: Expression was detected in V2b interneurons. There was some co-expression with Pax6 positive interneurons settled in the ventral spinal cord and not when they migrated out of the ventricular zone.
Specimen Label: 3D
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6360651
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360727
Age: embryonic day 14.5
Image: 4B
Note: Expression was detected in V2b interneurons. There was some co-expression with Pax6 positive interneurons settled in the ventral spinal cord and not when they migrated out of the ventricular zone.
Specimen Label: 4B
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7621468
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7621559
Age: embryonic day 12.5
Image: 6C ESCO2cKO
Note: In the conditional mutant, expression was lower in the lateral area of the cortex. Co-expression with Casp3 and Pax6 indicated that increased apoptosis was mainly in intermediate progenitor cells (Eomes+) and and cells in transition stage between radial glia progenitor cells/intermediate progenitor cells (Eomes+/Pax6+).
Specimen Label: 6C ESCO2cKO
Detected: true
Specimen Num: 6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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