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Search results 101 to 200 out of 1380 for a

Category restricted to InteractionExperiment (x)

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Categories

Category: InteractionExperiment
Type Details Score
Interaction Experiment
Description: Involvement of Rabring7 in EGF receptor degradation as an E3 ligase.
Interaction Experiment
Description: Caveolin-1 interacts with alpha-synuclein and mediates toxic actions of cellular alpha-synuclein overexpression.
Interaction Experiment
Description: Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes.
Interaction Experiment
Description: Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration.
Interaction Experiment
Description: Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice.
Interaction Experiment
Description: Two conserved domains in PCIF1 mediate interaction with pancreatic transcription factor PDX-1.
Interaction Experiment
Description: Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency.
Interaction Experiment
Description: Interactions in the network of Usher syndrome type 1 proteins.
Interaction Experiment
Description: The NH2-terminal propeptide of type I procollagen acts intracellularly to modulate cell function.
Interaction Experiment
Description: Kinesin light-chain KLC3 expression in testis is restricted to spermatids.
Interaction Experiment
Description: Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.
Interaction Experiment
Description: Impaired DNA damage checkpoint response in MIF-deficient mice.
Interaction Experiment
Description: Cell cycle adaptations of embryonic stem cells.
Interaction Experiment
Description: Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family.
Interaction Experiment
Description: An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway.
Interaction Experiment
Description: Antiproliferative role of dopamine: loss of D2 receptors causes hormonal dysfunction and pituitary hyperplasia.
Interaction Experiment
Description: Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors.
Interaction Experiment
Description: Regulation of endogenous SH2 domain-containing inositol 5-phosphatase (SHIP2) in 3T3-L1 and human preadipocytes.
Interaction Experiment
Description: Crosstalk between PKCzeta and the IL4/Stat6 pathway during T-cell-mediated hepatitis.
Interaction Experiment
Description: Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation.
Interaction Experiment
Description: Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity.
Interaction Experiment
Description: The clathrin adaptor Dab2 recruits EH domain scaffold proteins to regulate integrin 1 endocytosis.
Interaction Experiment
Description: Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex.
Interaction Experiment
Description: Alix protein is substrate of Ozz-E3 ligase and modulates actin remodeling in skeletal muscle.
Interaction Experiment
Description: ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.
Interaction Experiment
Description: Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies.
Interaction Experiment
Description: Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D.
Interaction Experiment
Description: Competitive regulation of E-cadherin juxtamembrane domain degradation by p120-catenin binding and Hakai-mediated ubiquitination.
Interaction Experiment
Description: Transcription suppression of thromboxane receptor gene by peroxisome proliferator-activated receptor-gamma via an interaction with Sp1 in vascular smooth muscle cells.
Interaction Experiment
Description: Insulin stimulates the tyrosine dephosphorylation of docking protein p130cas (Crk-associated substrate), promoting the switch of the adaptor protein crk from p130cas to newly phosphorylated insulin receptor substrate-1.
Interaction Experiment
Description: Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
Interaction Experiment
Description: ATM mediates pRB function to control DNMT1 protein stability and DNA methylation
Interaction Experiment
Description: MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2.
Interaction Experiment
Description: COP1 targets C/EBP for degradation and induces acute myeloid leukemia via Trib1.
Interaction Experiment
Description: Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.
Interaction Experiment
Description: The Aurora B Kinase and the Polycomb Protein Ring1B Combine to Regulate Active Promoters in Quiescent Lymphocytes.
Interaction Experiment
Description: Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.
Interaction Experiment
Description: Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis.
Interaction Experiment
Description: Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15.
Interaction Experiment
Description: Cullin 5 destabilizes Cas to inhibit Src-dependent cell transformation.
Interaction Experiment
Description: Ligand-of-Numb protein X is an endocytic scaffold for junctional adhesion molecule 4.
Interaction Experiment
Description: Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch.
Interaction Experiment
Description: Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1
Interaction Experiment
Description: Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein.
Interaction Experiment
Description: Cytolethal Distending Toxins Require Components of the ER-Associated Degradation Pathway for Host Cell Entry.
Interaction Experiment
Description: KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy.
Interaction Experiment
Description: Regulation of mTOR and cell growth in response to energy stress by REDD1.
Interaction Experiment
Description: Grail controls Th2 cell development by targeting STAT6 for degradation.
Interaction Experiment
Description: Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.
Interaction Experiment
Description: Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.
Interaction Experiment
Description: Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair.
Interaction Experiment
Description: SUMO regulates proteasome-dependent degradation of FLASH/Casp8AP2.
Interaction Experiment
Description: Targeted disruption of neuronal 19S proteasome subunits induces the formation of ubiquitinated inclusions in the absence of cell death.
Interaction Experiment
Description: Processing body movement in Arabidopsis thaliana depends on an interaction between myosins and DCP1.
Interaction Experiment
Description: Grsf1-induced translation of the SNARE protein Use1 is required for expansion of the erythroid compartment.
Interaction Experiment
Description: Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.
Interaction Experiment
Description: Parkin regulates kainate receptors by interacting with the GluK2 subunit.
Interaction Experiment
Description: Regulation of E2F1-induced apoptosis by poly(ADP-ribosyl)ation.
Interaction Experiment
Description: Gonadotropin gene transcription is activated by menin-mediated effects on the chromatin.
Interaction Experiment
Description: Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.
Interaction Experiment
Description: The effects of WW2/WW3 domains of Smurf2 molecule on TGF- signaling and arginase I gene expression.
Interaction Experiment
Description: Control of glioblastoma tumorigenesis by feed-forward cytokine signaling.
Interaction Experiment
Description: Apolipoprotein E controls ATP-binding cassette transporters in the ischemic brain.
Interaction Experiment
Description: Phosphorylation of CHO1 by Lats1/2 regulates the centrosomal activation of LIMK1 during cytokinesis.
Interaction Experiment
Description: P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3.
Interaction Experiment
Description: Toll-like Receptor (TLR) Signaling Interacts with CREBH to Modulate High-density Lipoprotein (HDL) in Response to Bacterial Endotoxin.
Interaction Experiment
Description: Disruption of the Phosphate Transporter Pit1 in Hepatocytes Improves Glucose Metabolism and Insulin Signaling by Modulating the USP7/IRS1 Interaction.
Interaction Experiment
Description: Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response.
Interaction Experiment
Description: Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.
Interaction Experiment
Description: EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.
Interaction Experiment
Description: Serine/threonine phosphorylation of ShcA. Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling.
Interaction Experiment
Description: p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis.
Interaction Experiment
Description: Smurf2-Mediated Stabilization of DNA Topoisomerase II Controls Genomic Integrity.
Interaction Experiment
Description: USP9X counteracts differential ubiquitination of NPHP5 by MARCH7 and BBS11 to regulate ciliogenesis.
Interaction Experiment
Description: p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer.
Interaction Experiment
Description: Structural insight into the specific interaction between murine SHPS-1/SIRP alpha and its ligand CD47.
Interaction Experiment
Description: Cross-activating c-Met/1 integrin complex drives metastasis and invasive resistance in cancer.
Interaction Experiment
Description: Conserved regulation of the Jak/STAT pathway by the endosomal protein asrij maintains stem cell potency.
Interaction Experiment
Description: Specific dephosphorylation at tyr-554 of git1 by ptprz promotes its association with paxillin and hic-5.
Interaction Experiment
Description: Calsyntenin-1 docks vesicular cargo to kinesin-1.
Interaction Experiment
Description: Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock.
Interaction Experiment
Description: Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.
Interaction Experiment
Description: Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration.
Interaction Experiment
Description: APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development.
Interaction Experiment
Description: DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components.
Interaction Experiment
Description: gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins.
Interaction Experiment
Description: DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells.
Interaction Experiment
Description: Autophagy genes in myeloid cells counteract IFN?-induced TNF-mediated cell death and fatal TNF-induced shock.
Interaction Experiment
Description: CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.
Interaction Experiment
Description: Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.
Interaction Experiment
Description: ?arrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1.
Interaction Experiment
Description: Identification of transmembrane protein 168 mutation in familial Brugada syndrome.
Interaction Experiment
Description: Alternative splicing of the mouse profilin II gene generates functionally different profilin isoforms.
Interaction Experiment
Description: Overlapping binding sites for importin ?1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization.
Interaction Experiment
Description: PIAS1 and TIF1? collaborate to promote SnoN SUMOylation and suppression of epithelial-mesenchymal transition.
Interaction Experiment
Description: Cell adhesion molecule close homolog of L1 binds to the dopamine receptor D2 and inhibits the internalization of its short isoform.
Interaction Experiment
Description: Expression of mRNA and protein-protein interaction of the antiviral endoribonuclease RNase L in mouse spleen.
Interaction Experiment
Description: Probing cellular protein complexes using single-molecule pull-down.
Interaction Experiment
Description: ATM loss disrupts the autophagy-lysosomal pathway.
Interaction Experiment
Description: STUB1/CHIP promotes ubiquitination and degradation of HIV-1 Vif to restore the cellular level of APOBEC3G protein.