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Search results 1001 to 1100 out of 1380 for a

Category restricted to InteractionExperiment (x)

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Categories

Category: InteractionExperiment
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Type Details Score
Interaction Experiment
Xiong Y (2011)
Description: A CSF-1 receptor phosphotyrosine 559 signaling pathway regulates receptor ubiquitination and tyrosine phosphorylation.
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Interaction Experiment
Gould KA (1996)
Description: Mom1 is a semi-dominant modifier of intestinal adenoma size and multiplicity in Min/+ mice.
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Interaction Experiment
Tian QB (2003)
Description: A novel ubiquitin-specific protease, synUSP, is localized at the post-synaptic density and post-synaptic lipid raft.
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Interaction Experiment
Arur S (2011)
Description: MPK-1 ERK controls membrane organization in C. elegans oogenesis via a sex-determination module.
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Interaction Experiment
Crosetto N (2008)
Description: Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner.
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Interaction Experiment
Klint P (2004)
Description: Translocated in liposarcoma (TLS) is a substrate for fibroblast growth factor receptor-1.
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Interaction Experiment
Barhite S (1998)
Description: Phosducin-like protein (PhLP), a regulator of G beta gamma function, interacts with the proteasomal protein SUG1.
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Interaction Experiment
Dragoni I (2006)
Description: The cold and menthol receptor TRPM8 contains a functionally important double cysteine motif.
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Interaction Experiment
Farhang-Fallah J (2000)
Description: Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.
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Interaction Experiment
Prag S (2004)
Description: Molecular analysis of muskelin identifies a conserved discoidin-like domain that contributes to protein self-association.
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Interaction Experiment
Graf SA (2004)
Description: Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABC-me).
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Interaction Experiment
Yoo KW (2006)
Description: Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish.
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Interaction Experiment
Rut W (2020)
Description: Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.
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Interaction Experiment
Litovchick L (2002)
Description: A selective interaction between OS-9 and the carboxyl-terminal tail of meprin beta.
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Interaction Experiment
Ashrafian H (2010)
Description: A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy.
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Interaction Experiment
Liu J (2000)
Description: A cysteine residue in the helix-loop-helix domain of Id2 is critical for homodimerization and function.
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Interaction Experiment
Zanger K (1999)
Description: A novel mechanism for cyclic adenosine 3,5-monophosphate regulation of gene expression by CREB-binding protein.
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Interaction Experiment
McLellan LK (2021)
Description: A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis.
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Interaction Experiment
Traub LM (1999)
Description: Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly.
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Interaction Experiment
Spencer JA (2000)
Description: Regulation of microtubule dynamics and myogenic differentiation by MURF, a striated muscle RING-finger protein.
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Interaction Experiment
Pan J (2005)
Description: RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis.
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Interaction Experiment
Duan W (2000)
Description: Cloning and characterization of AWP1, a novel protein that associates with serine/threonine kinase PRK1 in vivo.
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Interaction Experiment
Suto RK (2000)
Description: Crystal structure of a nucleosome core particle containing the variant histone H2A.Z.
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Interaction Experiment
Wickham L (1999)
Description: Mammalian staufen is a double-stranded-RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum.
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Interaction Experiment
Park U (2024)
Description: A humanized ACE2 mouse model recapitulating age- and sex-dependent immunopathogenesis of COVID-19.
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Interaction Experiment
Willard MD (2007)
Description: Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation.
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Interaction Experiment
Hayashi K (2008)
Description: Defective assembly of a hybrid vacuolar H(+)-ATPase containing the mouse testis-specific E1 isoform and yeast subunits.
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Interaction Experiment
Tsai CC (1999)
Description: SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.
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Interaction Experiment
Aoki T (1999)
Description: TIP120B: a novel TIP120-family protein that is expressed specifically in muscle tissues.
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Interaction Experiment
Gao Y (2000)
Description: Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide.
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Interaction Experiment
Lewitzky M (2004)
Description: Mona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix.
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Interaction Experiment
Del Prete D (2016)
Description: Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.
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Interaction Experiment
Choi E (2005)
Description: Characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor.
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Interaction Experiment
Huang N (1998)
Description: Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators.
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Interaction Experiment
Kao HY (2000)
Description: Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.
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Interaction Experiment
Tomsig JL (2003)
Description: Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.
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Interaction Experiment
Kong M (2002)
Description: Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation.
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Interaction Experiment
Vijapurkar U (1998)
Description: Mutation of a Shc binding site tyrosine residue in ErbB3/HER3 blocks heregulin-dependent activation of mitogen-activated protein kinase.
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Interaction Experiment
Lim R (2002)
Description: MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1.
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Interaction Experiment
Okabe T (2003)
Description: RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling.
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Interaction Experiment
Kurschner C (1998)
Description: CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.
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Interaction Experiment
Fiorentino L (2000)
Description: Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain.
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Interaction Experiment
Lang D (1998)
Description: The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness.
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Interaction Experiment
Howes E (2001)
Description: Interactions between mouse ZP2 glycoprotein and proacrosin; a mechanism for secondary binding of sperm to the zona pellucida during fertilization.
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Interaction Experiment
Goutebroze L (2000)
Description: Cloning and characterization of SCHIP-1, a novel protein interacting specifically with spliced isoforms and naturally occurring mutant NF2 proteins.
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Interaction Experiment
Fang S (2001)
Description: The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum.
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Interaction Experiment
Guo H (2008)
Description: Osteopontin mediates Stat1 degradation to inhibit iNOS transcription in a cecal ligation and puncture model of sepsis.
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Interaction Experiment
Dehring DA (2008)
Description: A C-terminal sequence in the guanine nucleotide exchange factor Sec7 mediates Golgi association and interaction with the Rsp5 ubiquitin ligase.
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Interaction Experiment
Cho MK (2007)
Description: Role of Galpha12 and Galpha13 as novel switches for the activity of Nrf2, a key antioxidative transcription factor.
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Interaction Experiment
Cattin AL (2009)
Description: Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.
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Interaction Experiment
Fallon L (2006)
Description: A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling.
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Interaction Experiment
Nedumaran B (2009)
Description: DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression.
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Interaction Experiment
Deshpande AM (2007)
Description: PHC3, a component of the hPRC-H complex, associates with E2F6 during G0 and is lost in osteosarcoma tumors.
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Interaction Experiment
Garcia-Pedrero JM (2006)
Description: The SWI/SNF chromatin remodeling subunit BAF57 is a critical regulator of estrogen receptor function in breast cancer cells.
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Interaction Experiment
Lee J (2009)
Description: A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4.
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Interaction Experiment
Brown CO (2004)
Description: The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer.
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Interaction Experiment
Roy SK (2005)
Description: A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{beta}-dependent gene expression in response to interferon-{gamma}.
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Interaction Experiment
Bamforth SD (2001)
Description: Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator.
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Interaction Experiment
Senawong T (2005)
Description: BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression.
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Interaction Experiment
Ju BG (2004)
Description: Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway.
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Interaction Experiment
Li H (2008)
Description: The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma.
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Interaction Experiment
Polioudaki H (2001)
Description: Histones H3/H4 form a tight complex with the inner nuclear membrane protein LBR and heterochromatin protein 1.
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Interaction Experiment
Mathur M (2001)
Description: PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors.
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Interaction Experiment
Khetchoumian K (2004)
Description: TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.
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Interaction Experiment
Kaitna S (2000)
Description: Incenp and an aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis.
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Interaction Experiment
Eilers AL (1999)
Description: A 13-amino acid amphipathic alpha-helix is required for the functional interaction between the transcriptional repressor Mad1 and mSin3A.
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Interaction Experiment
Nomura T (1999)
Description: Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor.
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Interaction Experiment
Stiegler P (1998)
Description: The COOH-terminal region of pRb2/p130 binds to histone deacetylase 1 (HDAC1), enhancing transcriptional repression of the E2F-dependent cyclin A promoter.
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Interaction Experiment
Matsuda S (2004)
Description: A Conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP.
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Interaction Experiment
Kirschenbaum F (2001)
Description: Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.
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Interaction Experiment
Kawazu M (2011)
Description: Histone Demethylase JMJD2B Functions as a Co-Factor of Estrogen Receptor in Breast Cancer Proliferation and Mammary Gland Development.
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Interaction Experiment
Bagheri-Fam S (2011)
Description: Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome.
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Interaction Experiment
Sanchez C (2007)
Description: Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.
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Interaction Experiment
Miyake S (1999)
Description: Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain.
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Interaction Experiment
Kanamaluru D (2011)
Description: Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner.
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Interaction Experiment
Kao YS (2011)
Description: A novel cross-talk between endothelin-1 and cyclic AMP signaling pathways in the regulation of GLUT1 transcription in 3T3-L1 adipocytes.
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Interaction Experiment
Inouye S (2007)
Description: Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor.
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Interaction Experiment
Miller SA (2010)
Description: Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression.
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Interaction Experiment
Luo B (2011)
Description: Role of suppressor of cytokine signaling 3 in lipid metabolism: Analysis based on a phage-display human liver cDNA library.
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Interaction Experiment
Tseng LA (2011)
Description: Interaction of an intracellular pentraxin with a BTB-Kelch protein is associated with ubiquitylation, aggregation and neuronal apoptosis.
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Interaction Experiment
Yang F (2010)
Description: The ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule pathway, stabilizes Tex19.1 during spermatogenesis.
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Interaction Experiment
Scott MJ (2009)
Description: Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism.
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Interaction Experiment
Bareiss S (2010)
Description: Delta-catenin/NPRAP: A new member of the glycogen synthase kinase-3beta signaling complex that promotes beta-catenin turnover in neurons.
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Interaction Experiment
Chen BB (2009)
Description: Masking of a nuclear signal motif by monoubiquitination leads to mislocalization and degradation of the regulatory enzyme cytidylyltransferase.
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Interaction Experiment
Babon JJ (2009)
Description: The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression.
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Interaction Experiment
Tran H (2008)
Description: Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.
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Interaction Experiment
Pan JA (2011)
Description: Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranes.
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Interaction Experiment
Lin JR (2011)
Description: SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis.
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Interaction Experiment
Yuk JM (2011)
Description: The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors.
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Interaction Experiment
Tsuda H (2008)
Description: The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors.
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Interaction Experiment
Whitehouse CA (2010)
Description: Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity.
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Interaction Experiment
Gnesutta N (2001)
Description: Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1.
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Interaction Experiment
Fognani C (2000)
Description: cRel-TD kinase: a serine/threonine kinase binding in vivo and in vitro c-Rel and phosphorylating its transactivation domain.
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Interaction Experiment
Proietti CJ (2011)
Description: Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer.
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Interaction Experiment
Zearfoss NR (2008)
Description: A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus.
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Interaction Experiment
Lackovic J (2012)
Description: Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke.
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Interaction Experiment
Wei SJ (2008)
Description: Identification of a specific motif of the DSS1 protein required for proteasome interaction and p53 protein degradation.
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Interaction Experiment
Oguro H (2012)
Description: Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes.
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Interaction Experiment
Kadlec L (1997)
Description: The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation.
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Interaction Experiment
Zhang N (2012)
Description: Repression of PDGF-R- after cellular injury involves TNF-, formation of a c-Fos-YY1 complex, and negative regulation by HDAC.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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