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Search results 1101 to 1200 out of 1380 for a

Category restricted to InteractionExperiment (x)

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Categories

Category: InteractionExperiment
Type Details Score
Interaction Experiment
Description: A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.
Interaction Experiment
Description: A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.
Interaction Experiment
Description: A CC loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.
Interaction Experiment
Description: Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase.
Interaction Experiment
Description: Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation.
Interaction Experiment
Description: A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein.
Interaction Experiment
Description: A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis.
Interaction Experiment
Description: Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice.
Interaction Experiment
Description: A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord.
Interaction Experiment
Description: The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX.
Interaction Experiment
Description: A screen for proteins that interact with PAX6: C-terminal mutations disrupt interaction with HOMER3, DNCL1 and TRIM11.
Interaction Experiment
Description: A juxtamembrane tyrosine in the colony stimulating factor-1 receptor regulates ligand-induced Src association, receptor kinase function, and down-regulation.
Interaction Experiment
Description: A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.
Interaction Experiment
Description: A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian orthologue of Chlamydomonas PF16.
Interaction Experiment
Description: A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor.
Interaction Experiment
Description: Cloning and characterization of a novel Kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RB.
Interaction Experiment
Description: BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.
Interaction Experiment
Description: A comparative study of Eya1 and Eya4 protein function and its implication in branchio-oto-renal syndrome and DFNA10.
Interaction Experiment
Description: Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development.
Interaction Experiment
Description: E3 ubiquitin ligase Smurf1 mediates core-binding factor alpha1/Runx2 degradation and plays a specific role in osteoblast differentiation.
Interaction Experiment
Description: A novel isoform of Vinexin, Vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad.
Interaction Experiment
Description: Nectin-like molecule 1 is a protein 4.1N associated protein and recruits protein 4.1N from cytoplasm to the plasma membrane.
Interaction Experiment
Description: Interaction of heterotrimeric G protein Galphao with Purkinje cell protein-2. Evidence for a novel nucleotide exchange factor.
Interaction Experiment
Description: Molecular cloning and characterization of CRLM-2, a novel type I cytokine receptor preferentially expressed in hematopoietic cells.
Interaction Experiment
Description: Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells.
Interaction Experiment
Description: A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.
Interaction Experiment
Description: The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin.
Interaction Experiment
Description: Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptor.
Interaction Experiment
Description: Type F scavenger receptor SREC-I interacts with advillin, a member of the gelsolin/villin family, and induces neurite-like outgrowth.
Interaction Experiment
Description: A direct interaction between the N terminus of adenylyl cyclase AC8 and the catalytic subunit of protein phosphatase 2A.
Interaction Experiment
Description: KLF11 mediates a critical mechanism in TGF-beta signaling that is inactivated by Erk-MAPK in pancreatic cancer cells.
Interaction Experiment
Description: A novel conserved isoform of the ubiquitin ligase UFD2a/UBE4B is expressed exclusively in mature striated muscle cells.
Interaction Experiment
Description: Barentsz, a new component of the Staufen-containing ribonucleoprotein particles in mammalian cells, interacts with Staufen in an RNA-dependent manner.
Interaction Experiment
Description: TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1.
Interaction Experiment
Description: Identification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse Btk.
Interaction Experiment
Description: Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis.
Interaction Experiment
Description: A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.
Interaction Experiment
Description: Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain.
Interaction Experiment
Description: MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
Interaction Experiment
Description: Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity.
Interaction Experiment
Description: Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator.
Interaction Experiment
Description: p67 isoform of mouse disabled 2 protein acts as a transcriptional activator during the differentiation of F9 cells.
Interaction Experiment
Description: p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation.
Interaction Experiment
Description: A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins.
Interaction Experiment
Description: Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway.
Interaction Experiment
Description: PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice.
Interaction Experiment
Description: Binding and phosphorylation of a novel male germ cell-specific cGMP-dependent protein kinase-anchoring protein by cGMP-dependent protein kinase Ialpha.
Interaction Experiment
Description: 14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitination and cytoplasmic body formation.
Interaction Experiment
Description: LPS induces the interaction of a transcription factor, LPS-induced TNF-alpha factor, and STAT6(B) with effects on multiple cytokines.
Interaction Experiment
Description: A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.
Interaction Experiment
Description: Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) is a negative regulator of the mammalian target of rapamycin complex 1 (mTORC1).
Interaction Experiment
Description: A dominant-negative form of mouse SOX2 induces trophectoderm differentiation and progressive polyploidy in mouse embryonic stem cells.
Interaction Experiment
Description: A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways.
Interaction Experiment
Description: G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator.
Interaction Experiment
Description: Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1.
Interaction Experiment
Description: Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2.
Interaction Experiment
Description: Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells.
Interaction Experiment
Description: LIM kinase 1, a key regulator of actin dynamics, is widely expressed in embryonic and adult tissues.
Interaction Experiment
Description: An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles.
Interaction Experiment
Description: The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain.
Interaction Experiment
Description: Identification of a Novel Anti-apoptotic E3 Ubiquitin Ligase That Ubiquitinates Antagonists of Inhibitor of Apoptosis Proteins SMAC, HtrA2, and ARTS.
Interaction Experiment
Description: The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).
Interaction Experiment
Description: Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3.
Interaction Experiment
Description: Characterization of mouse brain-specific angiogenesis inhibitor 1 (BAI1) and phytanoyl-CoA alpha-hydroxylase-associated protein 1, a novel BAI1-binding protein.
Interaction Experiment
Description: High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis.
Interaction Experiment
Description: The protein of a new gene, Tctex4, interacts with protein kinase CK2beta subunit and is highly expressed in mouse testis.
Interaction Experiment
Description: The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos.
Interaction Experiment
Description: A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.
Interaction Experiment
Description: Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.
Interaction Experiment
Description: Promoter occupancy of MLL1 histone methyltransferase seems to specify the proliferative and apoptotic functions of E2F1 in a tumour microenvironment.
Interaction Experiment
Description: A Distinct Role of Riplet-Mediated K63-Linked Polyubiquitination of the RIG-I Repressor Domain in Human Antiviral Innate Immune Responses.
Interaction Experiment
Description: Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase.
Interaction Experiment
Description: p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation.
Interaction Experiment
Description: Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor.
Interaction Experiment
Description: Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling.
Interaction Experiment
Description: Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons.
Interaction Experiment
Description: Endoplasmic reticulum-associated ubiquitin conjugating enzyme- Ube2j1 is a novel substrate of MAPKAP kinase-2 involved in MK2-mediated TNF production.
Interaction Experiment
Description: In vivo genome-wide binding of Id2 to E2F4 target genes as part of a reversible program in mice liver.
Interaction Experiment
Description: Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.
Interaction Experiment
Description: P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP.
Interaction Experiment
Description: Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice.
Interaction Experiment
Description: A porphobilinogen deaminase (PBGD) Ran-binding protein interaction is implicated in nuclear trafficking of PBGD in differentiating glioma cells.
Interaction Experiment
Description: The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins.
Interaction Experiment
Description: Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.
Interaction Experiment
Description: CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression.
Interaction Experiment
Description: Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.
Interaction Experiment
Description: The Ubiquitin Ligase Synoviolin Up-regulates Amyloid Production by Targeting a Negative Regulator of -Secretase, Rer1, for Degradation.
Interaction Experiment
Description: HSP72 is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal Muscle.
Interaction Experiment
Description: Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl.
Interaction Experiment
Description: An initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, COP1.
Interaction Experiment
Description: Zfp819, a novel KRAB-zinc finger protein, interacts with KAP1 and functions in genomic integrity maintenance of mouse embryonic stem cells.
Interaction Experiment
Description: The Guanine nucleotide exchange factor kalirin-7 is a novel synphilin-1 interacting protein and modifies synphilin-1 aggregate transport and formation.
Interaction Experiment
Description: Ubiquitously expressed transcript is a novel interacting protein of protein inhibitor of activated signal transducer and activator of transcription 2.
Interaction Experiment
Description: SPSB1, a Novel Negative Regulator of the Transforming Growth Factor- Signaling Pathway Targeting the Type II Receptor.
Interaction Experiment
Description: The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor.
Interaction Experiment
Description: A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways.
Interaction Experiment
Description: Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1.
Interaction Experiment
Description: Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.
Interaction Experiment
Description: The Fes protein-tyrosine kinase phosphorylates a subset of macrophage proteins that are involved in cell adhesion and cell-cell signaling.
Interaction Experiment
Description: The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor.