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Search results 1201 to 1300 out of 1380 for a

Category restricted to InteractionExperiment (x)

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Categories

Category: InteractionExperiment
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Type Details Score
Interaction Experiment
Leavenworth JW (2015)
Description: A p85-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells.
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Interaction Experiment
Hutchins AP (2013)
Description: Co-motif discovery identifies an Esrrb-Sox2-DNA ternary complex as a mediator of transcriptional differences between mouse embryonic and epiblast stem cells.
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Interaction Experiment
ZeRuth GT (2015)
Description: HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity.
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Interaction Experiment
Sun J (2016)
Description: The 11S Proteasome Subunit PSME3 Is a Positive Feedforward Regulator of NF-B and Important for Host Defense against Bacterial Pathogens.
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Interaction Experiment
Inoue K (2006)
Description: Cohesin protein SMC1 represses the nuclear receptor CAR-mediated synergistic activation of a human P450 gene by xenobiotics.
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Interaction Experiment
Haines BP (2006)
Description: Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development.
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Interaction Experiment
Hsieh PC (2007)
Description: p53 downstream target DDA3 is a novel microtubule-associated protein that interacts with end-binding protein EB3 and activates beta-catenin pathway.
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Interaction Experiment
Fukaya M (2011)
Description: SynArfGEF is a guanine nucleotide exchange factor for Arf6 and localizes preferentially at post-synaptic specializations of inhibitory synapses.
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Interaction Experiment
Sun J (2004)
Description: Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptor.
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Interaction Experiment
Wang X (1999)
Description: Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilin.
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Interaction Experiment
Grose JH (2015)
Description: Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.
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Interaction Experiment
Hodskinson MR (2014)
Description: Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair.
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Interaction Experiment
Alzamora R (2010)
Description: PKA regulates vacuolar H+-ATPase localization and activity via direct phosphorylation of the a subunit in kidney cells.
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Interaction Experiment
Luebben SW (2014)
Description: A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.
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Interaction Experiment
Pastuzyn ED (2017)
Description: Activity-Dependent Arc Expression and Homeostatic Synaptic Plasticity Are Altered in Neurons from a Mouse Model of Angelman Syndrome.
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Interaction Experiment
Engqvist-Goldstein AE (1999)
Description: An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles.
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Interaction Experiment
Lando D (2000)
Description: A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1alpha and the HIF-like factor.
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Interaction Experiment
Torii S (2011)
Description: Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins.
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Interaction Experiment
Lee YW (2012)
Description: A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells.
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Interaction Experiment
Hunter M (2005)
Description: NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24.
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Interaction Experiment
Stemkowski PL (2017)
Description: Identification of interleukin-1 beta as a key mediator in the upregulation of Cav3.2-USP5 interactions in the pain pathway.
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Interaction Experiment
van Ham M (2003)
Description: Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL.
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Interaction Experiment
Zeng L (1999)
Description: Protein tyrosine phosphatase alpha (PTPalpha) and contactin form a novel neuronal receptor complex linked to the intracellular tyrosine kinase fyn.
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Interaction Experiment
Chantry D (1997)
Description: p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes.
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Interaction Experiment
Zhang M (2014)
Description: Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic cells.
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Interaction Experiment
Rochira JA (2011)
Description: A small peptide modeled after the NRAGE repeat domain inhibits XIAP-TAB1-TAK1 signaling for NF-B activation and apoptosis in P19 cells.
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Interaction Experiment
Srinivasan S (2013)
Description: Identification of PDCL3 as a novel chaperone protein involved in the generation of functional VEGF receptor 2.
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Interaction Experiment
Fujita H (2018)
Description: Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization.
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Interaction Experiment
Li S (2001)
Description: Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling.
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Interaction Experiment
Maurice P (2008)
Description: A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.
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Interaction Experiment
Tamberg N (2018)
Description: Keap1-MCM3 interaction is a potential coordinator of molecular machineries of antioxidant response and genomic DNA replication in metazoa.
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Interaction Experiment
Gisler SM (2008)
Description: Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system.
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Interaction Experiment
Tanabe Y (2015)
Description: CASPR2 forms a complex with GPR37 via MUPP1 but not with GPR37(R558Q), an autism spectrum disorder-related mutation.
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Interaction Experiment
Byun SH (2017)
Description: TRBP maintains mammalian embryonic neural stem cell properties by acting as a novel transcriptional coactivator of the Notch signaling pathway.
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Interaction Experiment
Williams JC (2006)
Description: The sarcolemmal calcium pump, alpha-1 syntrophin, and neuronal nitric-oxide synthase are parts of a macromolecular protein complex.
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Interaction Experiment
Mukai J (2000)
Description: NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR.
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Interaction Experiment
Pincheira R (2009)
Description: Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowth.
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Interaction Experiment
Yang C (2020)
Description: Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers.
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Interaction Experiment
Morimura N (2006)
Description: Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins.
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Interaction Experiment
Wang X (2021)
Description: Invivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target.
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Interaction Experiment
Fan J (2017)
Description: Down-regulation of T-type Cav3.2 channels by hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1): Evidence of a signaling complex.
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Interaction Experiment
Peng H (2009)
Description: Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.
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Interaction Experiment
Shen S (2021)
Description: circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1.
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Interaction Experiment
Burgermeister E (2006)
Description: A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.
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Interaction Experiment
Sadhukhan T (2021)
Description: In a mouse model of INCL reduced S-palmitoylation of cytosolic thioesterase APT1 contributes to microglia proliferation and neuroinflammation.
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Interaction Experiment
Gupta S (2022)
Description: Fibronectin containing alternatively spliced extra domain A interacts at the central and c-terminal domain of Toll-like receptor-4.
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Interaction Experiment
Forrest MP (2023)
Description: Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.
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Interaction Experiment
Sayyad Z (2023)
Description: A glaucoma-associated OPTN polymorphism, M98K sensitizes retinal cells to endoplasmic reticulum stress and tumour necrosis factor ?.
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Interaction Experiment
Arey RN (2014)
Description: An important role for cholecystokinin, a CLOCK target gene, in the development and treatment of manic-like behaviors.
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Interaction Experiment
Slabber CF (2023)
Description: The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.
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Interaction Experiment
Li PL (2023)
Description: Targeting peroxisome proliferator-activated receptor ? proteasomal degradation by magnolol is a potential avenue for adipogenesis-mediated metabolic homeostasis.
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Interaction Experiment
Ye M (2023)
Description: TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model.
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Interaction Experiment
Ogura T (2010)
Description: Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains.
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Interaction Experiment
Lehtonen S (2004)
Description: Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin.
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Interaction Experiment
Hashiguchi M (2008)
Description: Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses.
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Interaction Experiment
Yuan W (1999)
Description: The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance.
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Interaction Experiment
Imai T (1997)
Description: ERC-55, a binding protein for the papilloma virus E6 oncoprotein, specifically interacts with vitamin D receptor among nuclear receptors.
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Interaction Experiment
Giesemann T (2003)
Description: Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system.
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Interaction Experiment
Toleman C (2004)
Description: Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities.
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Interaction Experiment
Kitano J (2003)
Description: Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein association.
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Interaction Experiment
Brasher SV (2000)
Description: The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer.
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Interaction Experiment
Salehi AH (2000)
Description: NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis.
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Interaction Experiment
Maiti B (2005)
Description: Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.
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Interaction Experiment
Baliova M (2023)
Description: A Significant Difference in Core PDZ Interactivity of SARS-CoV, SARS-CoV2 and MERS-CoV Protein E Peptide PDZ Motifs In Vitro.
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Interaction Experiment
Zhao F (2001)
Description: Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation properties.
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Interaction Experiment
Brower CS (2010)
Description: Mouse Dfa is a repressor of TATA-box promoters and interacts with the Abt1 activator of basal transcription.
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Interaction Experiment
de Silva U (2007)
Description: The crystal structure of TREX1 explains the 3 nucleotide specificity and reveals a polyproline II helix for protein partnering.
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Interaction Experiment
Lou X (2022)
Description: Structural studies of the coiled-coil domain of TRIM75 reveal a tetramer architecture facilitating its E3 ligase complex.
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Interaction Experiment
Morgan D (2002)
Description: Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle.
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Interaction Experiment
Liu L (2005)
Description: Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5.
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Interaction Experiment
Tomotsune D (1999)
Description: A novel member of murine Polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro.
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Interaction Experiment
Quilliam LA (1999)
Description: M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6.
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Interaction Experiment
Wolfrum C (2001)
Description: Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha - and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus.
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Interaction Experiment
Yang T (2002)
Description: Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
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Interaction Experiment
Rouault JP (1998)
Description: Interaction of BTG1 and p53-regulated BTG2 gene products with mCaf1, the murine homolog of a component of the yeast CCR4 transcriptional regulatory complex.
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Interaction Experiment
Helaakoski T (1995)
Description: Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit.
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Interaction Experiment
Eby MT (2000)
Description: TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death.
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Interaction Experiment
Takaesu G (2000)
Description: TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway.
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Interaction Experiment
Tu Y (1998)
Description: Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.
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Interaction Experiment
Chen HI (1995)
Description: The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.
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Interaction Experiment
Linari M (1999)
Description: The delta subunit of rod specific cyclic GMP phosphodiesterase, PDE delta, interacts with the Arf-like protein Arl3 in a GTP specific manner.
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Interaction Experiment
Zuo Y (2006)
Description: Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter.
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Interaction Experiment
Jeong BC (2004)
Description: Androgen receptor corepressor-19 kDa (ARR19), a leucine-rich protein that represses the transcriptional activity of androgen receptor through recruitment of histone deacetylase.
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Interaction Experiment
Bhalla S (2004)
Description: Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism.
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Interaction Experiment
Schoorlemmer J (1997)
Description: Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain.
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Interaction Experiment
Yokota S (2001)
Description: Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a particular subunit species concomitant with substrate binding and folding activities during the cell cycle.
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Interaction Experiment
Duyndam MC (1999)
Description: The N-terminal transactivation domain of ATF2 is a target for the co-operative activation of the c-jun promoter by p300 and 12S E1A.
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Interaction Experiment
Berruti G (2010)
Description: USP8, a regulator of endosomal sorting, is involved in mouse acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules.
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Interaction Experiment
Thompson S (2011)
Description: Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection.
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Interaction Experiment
Rucci N (2005)
Description: A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells.
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Interaction Experiment
Christova T (2010)
Description: Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription.
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Interaction Experiment
Tang B (2012)
Description: Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease.
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Interaction Experiment
Kim S (2009)
Description: An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures.
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Interaction Experiment
Yang Y (2011)
Description: A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage.
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Interaction Experiment
Sattler M (1997)
Description: The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors.
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Interaction Experiment
Ghoshal K (2005)
Description: 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal.
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Interaction Experiment
Gibb SL (2007)
Description: A caspase-3-cleaved fragment of the glial glutamate transporter EAAT2 is sumoylated and targeted to promyelocytic leukemia nuclear bodies in mutant SOD1-linked amyotrophic lateral sclerosis.
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Interaction Experiment
Scott RE (2005)
Description: P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA.
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Interaction Experiment
Lu B (2003)
Description: Mouse GGN1 and GGN3, two germ cell-specific proteins from the single gene Ggn, interact with mouse POG and play a role in spermatogenesis.
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Interaction Experiment
Nawa M (2008)
Description: A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB.
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