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Search results 1301 to 1380 out of 1380 for a

Category restricted to InteractionExperiment (x)

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Category: InteractionExperiment
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Type Details Score
Interaction Experiment
Berti C (2004)
Description: Mig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubules.
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Interaction Experiment
Hill JJ (2003)
Description: Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains.
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Interaction Experiment
Fernandez E (2005)
Description: Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.
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Interaction Experiment
Maeda K (1999)
Description: A new member of the alpha4-related molecule (alpha4-b) that binds to the protein phosphatase 2A is expressed selectively in the brain and testis.
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Interaction Experiment
Koyano S (1999)
Description: A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1.
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Interaction Experiment
Mu ZM (2002)
Description: Pag, a putative tumor suppressor, interacts with the Myc Box II domain of c-Myc and selectively alters its biological function and target gene expression.
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Interaction Experiment
Sun T (2003)
Description: Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.
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Interaction Experiment
Laure L (2010)
Description: A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-B pathway in skeletal muscle.
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Interaction Experiment
Chung DH (2002)
Description: Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17.
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Interaction Experiment
Bhunia AK (2002)
Description: PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2.
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Interaction Experiment
Dul JL (1996)
Description: The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell development.
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Interaction Experiment
Song KS (1996)
Description: Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins.
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Interaction Experiment
MaCaulay SL (2003)
Description: Insulin stimulates movement of sorting nexin 9 between cellular compartments: a putative role mediating cell surface receptor expression and insulin action.
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Interaction Experiment
Korn C (2005)
Description: Interaction of DNA fragmentation factor (DFF) with DNA reveals an unprecedented mechanism for nuclease inhibition and suggests that DFF can be activated in a DNA-bound state.
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Interaction Experiment
Rosenbauer F (1999)
Description: Interferon consensus sequence binding protein and interferon regulatory factor-4/Pip form a complex that represses the expression of the interferon-stimulated gene-15 in macrophages.
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Interaction Experiment
Hsu LJ (2005)
Description: Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1.
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Interaction Experiment
Smythe GM (2003)
Description: A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes.
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Interaction Experiment
Ren XR (2001)
Description: Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.
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Interaction Experiment
Norwitz ER (2002)
Description: Direct binding of AP-1 (Fos/Jun) proteins to a SMAD binding element facilitates both gonadotropin-releasing hormone (GnRH)- and activin-mediated transcriptional activation of the mouse GnRH receptor gene.
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Interaction Experiment
Pilot-Storck F (2010)
Description: Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor.
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Interaction Experiment
Taler M (2003)
Description: Fer is a downstream effector of insulin and mediates the activation of signal transducer and activator of transcription 3 in myogenic cells.
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Interaction Experiment
Chang NS (2005)
Description: 17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo.
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Interaction Experiment
Murakami M (2006)
Description: Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.
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Interaction Experiment
Beer HD (2005)
Description: The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair.
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Interaction Experiment
Simbulan-Rosenthal CM (2003)
Description: PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase.
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Interaction Experiment
Shani G (2008)
Description: GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.
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Interaction Experiment
Yu Z (2001)
Description: mSiglec-E, a novel mouse CD33-related siglec (sialic acid-binding immunoglobulin-like lectin) that recruits Src homology 2 (SH2)-domain-containing protein tyrosine phosphatases SHP-1 and SHP-2.
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Interaction Experiment
Le Douarin B (1995)
Description: The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.
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Interaction Experiment
Doi H (2013)
Description: p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model.
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Interaction Experiment
An CI (2013)
Description: Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells.
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Interaction Experiment
Rodriguez-Ortiz CJ (2013)
Description: Neuronal-Specific Overexpression of a Mutant Valosin-Containing Protein Associated with IBMPFD Promotes Aberrant Ubiquitin and TDP-43 Accumulation and Cognitive Dysfunction in Transgenic Mice.
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Interaction Experiment
Hartman Z (2012)
Description: HER2 stabilizes EGFR and itself by altering autophosphorylation patterns in a manner that overcomes regulatory mechanisms and promotes proliferative and transformation signaling.
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Interaction Experiment
Sattler M (2001)
Description: SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL.
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Interaction Experiment
Yu ZY (2013)
Description: Physical and Functional Interaction of Rnf2 with Af9 Regulates Basal and Aldosterone-stimulated Transcription of the -ENaC Gene in a Renal Collecting Duct Cell Line.
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Interaction Experiment
Pizon V (2013)
Description: MURF2B, a Novel LC3-Binding Protein, Participates with MURF2A in the Switch between Autophagy and Ubiquitin Proteasome System during Differentiation of C2C12 Muscle Cells.
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Interaction Experiment
Madera-Salcedo IK (2013)
Description: Morphine prevents lipopolysaccharide-induced TNF secretion in mast cells blocking IB kinase activation and SNAP-23 phosphorylation: correlation with the formation of a -arrestin/TRAF6 complex.
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Interaction Experiment
Oestreich KJ (2012)
Description: Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile.
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Interaction Experiment
Cote SM (2013)
Description: Mutation of nonessential cysteines shows that the NF-B essential modulator forms a constitutive noncovalent dimer that binds IB kinase- with high affinity.
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Interaction Experiment
Murray RZ (2005)
Description: Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha.
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Interaction Experiment
Dey S (2008)
Description: Interactions between SIRT1 and AP-1 reveal a mechanistic insight into the growth promoting properties of alumina (Al2O3) nanoparticles in mouse skin epithelial cells.
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Interaction Experiment
Adler J (2010)
Description: c-Fos proteasomal degradation is activated by a default mechanism, and its regulation by NAD(P)H:quinone oxidoreductase 1 determines c-Fos serum response kinetics.
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Interaction Experiment
Hyndman BD (2012)
Description: Mapping acetylation sites in E2A identifies a conserved lysine residue in activation domain 1 that promotes CBP/p300 recruitment and transcriptional activation.
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Interaction Experiment
Yousef AF (2010)
Description: Identification of a molecular recognition feature in the E1A oncoprotein that binds the SUMO conjugase UBC9 and likely interferes with polySUMOylation.
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Interaction Experiment
Jin Y (2002)
Description: A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK.
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Interaction Experiment
Kennell JA (2003)
Description: T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors.
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Interaction Experiment
Janoueix-Lerosey I (1995)
Description: Two-hybrid system screen with the small GTP-binding protein Rab6. Identification of a novel mouse GDP dissociation inhibitor isoform and two other potential partners of Rab6.
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Interaction Experiment
Scholzen T (2002)
Description: The Ki-67 protein interacts with members of the heterochromatin protein 1 (HP1) family: a potential role in the regulation of higher-order chromatin structure.
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Interaction Experiment
Xie J (2015)
Description: Identification of C-terminal Hsp70-interacting protein as a mediator of tumour necrosis factor action in osteoblast differentiation by targeting osterix for degradation.
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Interaction Experiment
Sirohi K (2015)
Description: A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin.
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Interaction Experiment
Czub B (2016)
Description: TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory Subunit 4, Encoded by the PSMC1 Gene.
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Interaction Experiment
Ben-Tekaya H (2010)
Description: ADP ribosylation factors 1 and 4 and group VIA phospholipase A regulate morphology and intraorganellar traffic in the endoplasmic reticulum-Golgi intermediate compartment.
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Interaction Experiment
Nour N (2005)
Description: The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.
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Interaction Experiment
Lu Z (2008)
Description: Protein encoded by the Axin(Fu) allele effectively down-regulates Wnt signaling but exerts a dominant negative effect on c-Jun N-terminal kinase signaling.
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Interaction Experiment
Canali S (2016)
Description: Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice.
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Interaction Experiment
Aykul S (2017)
Description: Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic.
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Interaction Experiment
Nakayama S (2018)
Description: Degradation of the endoplasmic reticulum-anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3.
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Interaction Experiment
OBryan JP (1996)
Description: A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.
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Interaction Experiment
Hackett RH (1997)
Description: Mapping of a cytoplasmic domain of the human growth hormone receptor that regulates rates of inactivation of Jak2 and Stat proteins.
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Interaction Experiment
Pilkinton M (2007)
Description: Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex.
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Interaction Experiment
King TR (2000)
Description: Using a phage display library to identify basic residues in A-Raf required to mediate binding to the Src homology 2 domains of the p85 subunit of phosphatidylinositol 3-kinase.
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Interaction Experiment
Kiefer H (2009)
Description: Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3 processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.
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Interaction Experiment
Evans PR (2018)
Description: Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.
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Interaction Experiment
Li Wq (2010)
Description: Downstream of tyrosine kinase/docking protein 6, as a novel substrate of tropomyosin-related kinase C receptor, is involved in neurotrophin 3-mediated neurite outgrowth in mouse cortex neurons.
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Interaction Experiment
Kim EY (2008)
Description: Nephrin binds to the COOH terminus of a large-conductance Ca2+-activated K+ channel isoform and regulates its expression on the cell surface.
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Interaction Experiment
Bergemann AD (1995)
Description: ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites.
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Interaction Experiment
Hall FL (1991)
Description: Characterization of the cytoplasmic proline-directed protein kinase in proliferative cells and tissues as a heterodimer comprised of p34cdc2 and p58cyclin A.
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Interaction Experiment
Kara E (2018)
Description: A flow cytometry-based in vitro assay reveals that formation of apolipoprotein E (ApoE)-amyloid beta complexes depends on ApoE isoform and cell type.
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Interaction Experiment
Jung KT (2022)
Description: The role of autophagy in cadmium-induced acute toxicity in glomerular mesangial cells and tracking polyubiquitination of cytoplasmic p53 as a biomarker.
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Interaction Experiment
Koochaki SHJ (2022)
Description: A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common ? chain (CSF2RB) protein stability.
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Interaction Experiment
Li X (2023)
Description: USP24-dependent stabilization of Runx2 recruits a p300/NCOA3 complex to transactivate ADAMTS genes and promote degeneration of intervertebral disc in chronic inflammation mice.
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Interaction Experiment
Loo DT (1997)
Description: Analysis of 4-1BBL and laminin binding to murine 4-1BB, a member of the tumor necrosis factor receptor superfamily, and comparison with human 4-1BB.
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Interaction Experiment
Dufourcq P (2008)
Description: Regulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation.
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Interaction Experiment
Chazot PL (1994)
Description: Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule.
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Interaction Experiment
Matsui C (2008)
Description: Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF.
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Interaction Experiment
Hata Y (1995)
Description: A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic.
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Interaction Experiment
Kudryashova E (2005)
Description: Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin.
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Interaction Experiment
Blumer JB (2003)
Description: Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha.
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Interaction Experiment
Wan KF (2001)
Description: The inhibitory gamma subunit of the type 6 retinal cyclic guanosine monophosphate phosphodiesterase is a novel intermediate regulating p42/p44 mitogen-activated protein kinase signaling in human embryonic kidney 293 cells.
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Interaction Experiment
Ehrlich AT (2013)
Description: Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G() subunits in human embryonic kidney 293T cells.
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Interaction Experiment
Moss SJ (1992)
Description: Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular domains of the beta 1, gamma 2S, and gamma 2L subunits of the gamma-aminobutyric acid type A receptor.
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