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Search results 1 to 12 out of 12 for Brca1

Category restricted to InteractionExperiment (x)

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Category: InteractionExperiment
Type Details Score
Interaction Experiment
Description: BRCA1 suppresses osteopontin-mediated breast cancer.
Interaction Experiment
Description: BRCA1 is a negative modulator of the PRC2 complex.
Interaction Experiment
Description: The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity.
Interaction Experiment
Description: Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter.
Interaction Experiment
Description: BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
Interaction Experiment
Description: BRCA1 is a novel regulator of metabolic function in skeletal muscle.
Interaction Experiment
Description: BRCA1 regulates transforming growth factor- (TGF-1) signaling through Gadd45a by enhancing the protein stability of Smad4.
Interaction Experiment
Description: HTLV-1 Tax oncoprotein inhibits the estrogen-induced-ER -Mediated BRCA1 expression by interaction with CBP/p300 cofactors.
Interaction Experiment
Description: Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity.
Interaction Experiment
Description: BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.
Interaction Experiment
Description: E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks.
Interaction Experiment
Description: Deubiquitinase BAP1 regulates stability of BRCA1 protein and inactivates the NF-?B signaling to protect mice from sepsis-induced acute kidney injury.