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Search results 1 to 18 out of 18 for Sirt1

Category restricted to InteractionExperiment (x)

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Categories

Category: InteractionExperiment
Type Details Score
Interaction Experiment
Description: A nutrient-sensitive interaction between Sirt1 and HNF-1 regulates Crp expression.
Interaction Experiment
Description: Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma.
Interaction Experiment
Description: SIRT1 regulates circadian clock gene expression through PER2 deacetylation.
Interaction Experiment
Description: Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation.
Interaction Experiment
Description: Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation.
Interaction Experiment
Description: Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1.
Interaction Experiment
Description: SIRT1 Negatively Regulates the Activities, Functions, and Protein Levels of hMOF and TIP60.
Interaction Experiment
Description: SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages.
Interaction Experiment
Description: The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation.
Interaction Experiment
Description: CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage.
Interaction Experiment
Description: SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons.
Interaction Experiment
Description: BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression.
Interaction Experiment
Description: FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states.
Interaction Experiment
Description: Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.
Interaction Experiment
Description: SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.
Interaction Experiment
Description: The type III histone deacetylase Sirt1 suppresses p300- mediated histone H3 Lysine 56 acetylation at Bclaf1 promoter to inhibit T cell activation.
Interaction Experiment
Description: Interactions between SIRT1 and AP-1 reveal a mechanistic insight into the growth promoting properties of alumina (Al2O3) nanoparticles in mouse skin epithelial cells.
Interaction Experiment
Description: Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells.