Probable phospholipid-transporting ATPase IM (also known as ATP8B4) belongs to subfamily IV of the P-type ATPases family, whose members transport phospholipids across the membrane. It appears to be a component of a P4-ATPase flippase complex and can bind either CDC50A or CDC50B as its accessory protein []. ATPase IM is expressed throughout the brain and may be involved in Alzheimer's disease [].