This domain is found towards the C-terminal of BCAS3 and ATG18-like proteins from plants. In BCAS3, this domain seems to be important for PHAF1 interactions [].This entry includes BCAS3 from animals and AT18F/G/H from Arabidopsis. BCAS3 is a microtubule associated cell migration factor that has been linked to the development of breast cancer and angiogenesis []. It forms a complex with PHAF1 and associates with the preautophagosomal structure during both non-selective and selective autophagy [].AT18F/G/H are linked to autophagy [].
This entry includes BCAS3 from animals and AT18F/G/H from Arabidopsis. BCAS3 is a microtubule associated cell migration factor that has been linked to the development of breast cancer and angiogenesis []. It forms a complex with PHAF1 and associates with the preautophagosomal structure during both non-selective and selective autophagy [].AT18F/G/H are linked to autophagy [].
This entry includes protein broad-minded, which interacts with cell cycle-related kinase (CCRK) and together these proteins regulate ciliary membrane and axonemal growth []; and phagosome assembly factor 1 (PHAF1) and its homologues. PHAF1 and BCAS3 form a complex that affects the recruitment of several core autophagy proteins to the phagophore assembly site [].